Fungal Genomics

at Utrecht University

General Properties

Protein IDOphio5|4974
Gene name
Locationscaffold_4:77398..80996
Strand+
Gene length (bp)3598
Transcript length (bp)3291
Coding sequence length (bp)3288
Protein length (aa) 1096

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PFAM Domains

PFAM Domain ID Short name Long name E-value Start End
PF18829 Importin_rep_6 Importin repeat 6 6.0E-35 769 879
PF18808 Importin_rep_4 Importin repeat 1.9E-33 275 367
PF18816 Importin_rep_5 Importin repeat 2.1E-23 1011 1062
PF13513 HEAT_EZ HEAT-like repeat 1.0E-10 383 437
PF02985 HEAT HEAT repeat 2.6E-03 411 438
PF12460 MMS19_C RNAPII transcription regulator C-terminal 1.7E-10 449 566

Swissprot hits

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Swissprot ID Swissprot Description Start End E-value
sp|O74476|IMB3_SCHPO Importin subunit beta-3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sal3 PE=3 SV=1 7 1095 0.0E+00
sp|P32337|IMB3_YEAST Importin subunit beta-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSE1 PE=1 SV=2 1 1096 0.0E+00
sp|Q8BKC5|IPO5_MOUSE Importin-5 OS=Mus musculus GN=Ipo5 PE=1 SV=3 11 1074 0.0E+00
sp|O00410|IPO5_HUMAN Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4 11 1074 0.0E+00
sp|Q8BIV3|RNBP6_MOUSE Ran-binding protein 6 OS=Mus musculus GN=Ranbp6 PE=1 SV=3 11 1071 1.0E-172
[Show all]
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Swissprot ID Swissprot Description Start End E-value
sp|O74476|IMB3_SCHPO Importin subunit beta-3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sal3 PE=3 SV=1 7 1095 0.0E+00
sp|P32337|IMB3_YEAST Importin subunit beta-3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PSE1 PE=1 SV=2 1 1096 0.0E+00
sp|Q8BKC5|IPO5_MOUSE Importin-5 OS=Mus musculus GN=Ipo5 PE=1 SV=3 11 1074 0.0E+00
sp|O00410|IPO5_HUMAN Importin-5 OS=Homo sapiens GN=IPO5 PE=1 SV=4 11 1074 0.0E+00
sp|Q8BIV3|RNBP6_MOUSE Ran-binding protein 6 OS=Mus musculus GN=Ranbp6 PE=1 SV=3 11 1071 1.0E-172
sp|O60518|RNBP6_HUMAN Ran-binding protein 6 OS=Homo sapiens GN=RANBP6 PE=1 SV=2 11 1074 4.0E-171
sp|Q54EW3|IPO5_DICDI Probable importin-5 homolog OS=Dictyostelium discoideum GN=DDB_G0291650 PE=3 SV=1 12 1066 8.0E-81
sp|P40069|IMB4_YEAST Importin subunit beta-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KAP123 PE=1 SV=1 10 632 5.0E-21
sp|O60100|IMB4_SCHPO Probable importin subunit beta-4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap123 PE=3 SV=1 4 1048 2.0E-16
sp|Q8VI75|IPO4_MOUSE Importin-4 OS=Mus musculus GN=Ipo4 PE=1 SV=1 12 626 1.0E-15
sp|Q8H0U4|TNPO1_ARATH Transportin-1 OS=Arabidopsis thaliana GN=TRN1 PE=1 SV=1 354 571 3.0E-11
sp|B8ARW2|TNPO1_ORYSI Transportin-1 OS=Oryza sativa subsp. indica GN=OsI_18044 PE=2 SV=1 89 571 2.0E-10
sp|B9FDR3|TNPO1_ORYSJ Transportin-1 OS=Oryza sativa subsp. japonica GN=TRN1 PE=3 SV=2 354 571 3.0E-10
sp|Q9FJD4|IMB1_ARATH Importin subunit beta-1 OS=Arabidopsis thaliana GN=KPNB1 PE=1 SV=1 11 551 3.0E-07
sp|O14089|IMB2_SCHPO Importin subunit beta-2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap104 PE=3 SV=1 364 630 5.0E-07
sp|O13864|IMB1_SCHPO Importin subunit beta-1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=kap95 PE=3 SV=1 21 544 2.0E-06
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GO

GO Term Description Terminal node
GO:0005515 protein binding Yes
GO:0005488 binding No
GO:0003674 molecular_function No

SignalP

[Help with interpreting these statistics]
SignalP signal predicted Location
(based on Ymax)		 D score
(significance: > 0.45)
No 1 - 19 0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

Expression values

Label Description Expression (RPKM) Confidence interval (low) Confidence interval (high)
SC16a Pure fungal culture 157.43 69.17 245.68
CcL In ants, during behavior modification 106.90 50.75 163.05
CcD In ants, recently dead 141.35 64.21 218.49

Differential expression

Label1 Label2 Q-value Significant difference
SC16a CcL 0.154262 no
SC16a CcD 0.739935 no
CcL CcD 0.318749 no

Sequences

Type of sequenceSequence
Locus Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein >Ophio5|4974
MSLLSADVHTQLTQLLQALQSSDNDIRSQAEEHLQKNWTSTRPEVLLMGLVEQIQGADDNATRSFAAVIFRRISS
KTRKIETGENVDIFYSIPRNQAAVIRQKLLETLATEEDRAVRNKISDAVAEVARQYADNNDTWPELLGALFQLSQ
APEPEKRDNAFRVFTTTPSIIERQHEEAILQAFQKGFKDDAIRVRLAAMEAFASFFRTISKKVQTKYFPLISDVL
NILPPIKESQESEDLSKALLALIDLAESAPKMFKQLFHNLVQFNVSVIQDKELDSICRQNALELMATFADYAPSM
CRKDASYTNDMVTQCLSLMTDLGEDDDDAAEWLASDDLDQDESDQNHVAGEQTMDRLANKLGGQTILAPTFNWLP
RMMTSMAWRDRHAALMAISAISEGCRDLMIGELSQVLDLVVPALQDPHPRVRWAGCNALGQMSTDFAPKMQTDFF
DRVLKAIIPVLNSPAARVKSHAAAALVNFCEEAEKSVLEPYLDDLLSQLFQLLQSDKRYVQEQALSTIATIADAA
EAAFSKYYDTLMPLLVNVLQNQSEKEFRLLRSKAMECATLIALAVGRERLAADAMTLVNLLANIQTSITDADDPQ
AQYLMHCWGRMCRVLGADFMPFLDSVMPPVLELAMAKADIQLLDDDDQAEQINGEEGWEFVPLKGKMIGIRTSTM
DDKHMAIELLLVYAQTLEGSFAPFVANIMEKIALPGLAFFFHDPTRYISAKLVPYLLNSYKKAFGCPSNELAGLW
HLTVEKLLEVLTAEPSIETLAVMYQCFYESMQVIGRDCLSLEYMNRFIDAVHSTLEDYQDRVAQRAEDKEDATAD
DVEDEAEETLMAIEDDQTLLSDMNKAFHSIFRHHGAAFLPAWERLMSTYQGFLASSDSTQRQWGLCIVDDVLEYC
GPESHRYANCISQPLIDGCRDTSPAIRQAAAYGIGVAAHRGGAPWSQFLGGSVPFLFQITQVPDARNEDNVYATE
NACAALAKILHYNSGSVANVQAAITQWIDTLPVINDEEAAPYAYAYLAELIDQRHPAVMNQGSKLFVLIAQALEA
ETLQGQTATKVAVATKVLLTSANVDPMPLLQQFSQDSQRTIMGYFS
Coding >Ophio5|4974
ATGTCTTTGCTCTCTGCCGACGTCCACACCCAACTAACCCAGCTCCTCCAAGCCTTGCAGTCCTCCGATAATGAC
ATTCGCTCCCAGGCTGAGGAGCATCTCCAGAAGAACTGGACAAGCACTCGCCCCGAAGTCCTGTTGATGGGTCTT
GTCGAGCAGATCCAAGGCGCAGACGATAATGCCACTCGTTCCTTTGCTGCTGTCATATTTCGTCGCATCTCGTCC
AAAACACGAAAGATCGAGACGGGCGAGAATGTCGACATTTTCTACTCTATACCAAGAAACCAAGCCGCCGTCATT
CGTCAGAAGCTTCTTGAGACTCTTGCAACTGAGGAGGATCGTGCGGTCCGCAACAAGATCAGTGACGCCGTTGCC
GAGGTTGCGCGGCAGTACGCCGATAACAATGATACTTGGCCTGAGCTTCTTGGCGCCCTTTTCCAGCTCAGTCAA
GCGCCCGAACCCGAAAAACGCGACAACGCCTTCCGCGTCTTCACCACGACGCCGAGCATCATTGAGAGGCAGCAT
GAGGAGGCAATTCTTCAGGCGTTTCAGAAAGGCTTCAAGGACGATGCCATCAGGGTCCGTCTTGCGGCGATGGAA
GCCTTCGCTTCTTTCTTCAGAACCATCAGCAAGAAGGTGCAAACCAAATACTTCCCGTTAATCTCGGACGTGCTG
AACATTCTACCTCCGATCAAAGAGTCCCAGGAGTCGGAGGATCTGAGCAAGGCACTCTTGGCCCTCATCGATCTC
GCCGAGTCAGCGCCTAAAATGTTCAAGCAATTATTCCACAATCTCGTTCAGTTCAACGTCTCCGTCATTCAAGAC
AAGGAGCTCGACAGCATTTGCAGGCAAAATGCCCTCGAACTCATGGCTACCTTCGCCGACTACGCACCCTCAATG
TGCAGAAAGGACGCCTCTTACACGAATGACATGGTCACGCAGTGTCTTAGCTTGATGACCGACCTCGGCGAAGAC
GACGACGATGCCGCGGAGTGGCTCGCCTCTGACGATCTTGATCAAGACGAAAGCGATCAAAATCACGTGGCTGGC
GAGCAGACCATGGACCGTCTCGCCAACAAGCTCGGCGGCCAGACTATCCTGGCTCCCACATTCAACTGGCTTCCC
CGGATGATGACGTCCATGGCTTGGAGGGATCGACACGCGGCTCTGATGGCCATCTCGGCCATTTCAGAGGGATGC
CGGGACCTCATGATTGGGGAGCTCAGCCAGGTGCTGGATTTGGTTGTGCCAGCCCTGCAGGACCCGCACCCGCGC
GTTCGCTGGGCTGGATGCAACGCGCTGGGCCAGATGAGCACTGATTTCGCTCCGAAAATGCAGACTGACTTTTTC
GACAGAGTGCTCAAGGCCATCATCCCTGTCCTGAACTCTCCCGCGGCGCGCGTCAAGTCTCACGCGGCTGCGGCC
TTGGTCAACTTCTGCGAGGAAGCAGAGAAGTCCGTTCTGGAGCCATACCTGGACGATCTCCTATCTCAACTGTTT
CAGCTGCTTCAAAGCGACAAGCGCTACGTTCAGGAGCAGGCCTTGTCGACCATCGCCACCATTGCCGATGCGGCT
GAGGCAGCCTTTTCCAAGTATTACGACACGTTGATGCCTCTCCTCGTCAACGTGCTCCAGAACCAAAGCGAAAAG
GAATTTCGGCTTTTGCGCTCCAAGGCCATGGAATGTGCTACTCTCATCGCCCTGGCCGTCGGACGGGAACGGCTC
GCAGCCGATGCCATGACGCTCGTCAACCTCCTCGCCAACATACAGACCAGTATCACCGATGCCGATGACCCGCAG
GCGCAATATCTGATGCATTGCTGGGGCCGAATGTGCCGCGTGCTCGGCGCTGACTTCATGCCGTTTCTGGACAGC
GTCATGCCTCCCGTGCTGGAACTGGCCATGGCCAAAGCCGATATACAGTTGCTCGACGATGACGACCAAGCCGAG
CAGATCAATGGTGAGGAGGGCTGGGAGTTCGTCCCGCTCAAGGGCAAAATGATTGGTATTCGGACAAGTACCATG
GATGACAAGCACATGGCCATTGAGCTCTTGCTCGTCTATGCTCAGACCCTCGAGGGTTCGTTTGCGCCGTTTGTG
GCCAACATCATGGAGAAAATTGCCCTCCCTGGCCTTGCCTTCTTCTTCCACGATCCTACCCGTTACATCTCTGCG
AAACTGGTCCCCTACCTCTTGAACTCGTACAAGAAGGCTTTCGGTTGCCCCTCCAACGAACTTGCCGGTCTCTGG
CACTTGACTGTGGAGAAGCTGTTGGAGGTCTTGACGGCTGAGCCATCGATCGAGACGCTCGCGGTCATGTACCAA
TGCTTCTACGAGTCCATGCAGGTGATTGGCAGAGACTGCCTCAGCCTTGAATACATGAACCGGTTCATCGACGCG
GTTCATTCCACACTGGAGGACTACCAGGACAGGGTCGCCCAGCGTGCCGAGGATAAGGAGGATGCGACGGCTGAC
GATGTCGAAGACGAGGCCGAGGAGACTCTGATGGCCATCGAAGACGATCAAACTCTCTTATCGGACATGAATAAG
GCATTTCATTCCATTTTTAGGCATCACGGCGCGGCTTTCCTACCGGCTTGGGAGCGGCTCATGTCGACATATCAA
GGGTTTCTAGCGTCCTCTGACTCGACTCAGCGACAATGGGGGCTCTGCATCGTGGATGACGTGCTGGAGTACTGC
GGGCCCGAGAGCCATCGGTATGCCAACTGCATTTCGCAACCTCTCATCGACGGCTGCAGGGACACGTCACCCGCC
ATCAGGCAGGCCGCTGCTTATGGTATCGGCGTTGCGGCTCATCGCGGCGGAGCACCCTGGTCTCAGTTCCTGGGA
GGGTCAGTGCCGTTTCTGTTCCAGATAACACAGGTGCCCGATGCCAGAAACGAGGACAACGTCTACGCTACGGAG
AACGCATGCGCTGCCTTGGCGAAAATTTTGCACTACAATTCTGGCAGCGTTGCAAACGTCCAAGCTGCGATTACG
CAGTGGATAGACACGTTACCGGTGATCAACGATGAAGAGGCGGCGCCGTATGCCTATGCCTATCTGGCCGAGCTT
ATTGATCAACGCCACCCTGCGGTCATGAACCAAGGCAGCAAGCTGTTCGTGTTGATCGCCCAGGCTCTCGAAGCC
GAGACTCTTCAGGGGCAGACAGCCACGAAAGTGGCAGTAGCCACGAAAGTGCTACTCACAAGTGCCAACGTGGAC
CCGATGCCGCTGCTCCAGCAGTTCTCGCAAGACTCGCAGCGAACAATTATGGGGTACTTCAGC
Transcript >Ophio5|4974
ATGTCTTTGCTCTCTGCCGACGTCCACACCCAACTAACCCAGCTCCTCCAAGCCTTGCAGTCCTCCGATAATGAC
ATTCGCTCCCAGGCTGAGGAGCATCTCCAGAAGAACTGGACAAGCACTCGCCCCGAAGTCCTGTTGATGGGTCTT
GTCGAGCAGATCCAAGGCGCAGACGATAATGCCACTCGTTCCTTTGCTGCTGTCATATTTCGTCGCATCTCGTCC
AAAACACGAAAGATCGAGACGGGCGAGAATGTCGACATTTTCTACTCTATACCAAGAAACCAAGCCGCCGTCATT
CGTCAGAAGCTTCTTGAGACTCTTGCAACTGAGGAGGATCGTGCGGTCCGCAACAAGATCAGTGACGCCGTTGCC
GAGGTTGCGCGGCAGTACGCCGATAACAATGATACTTGGCCTGAGCTTCTTGGCGCCCTTTTCCAGCTCAGTCAA
GCGCCCGAACCCGAAAAACGCGACAACGCCTTCCGCGTCTTCACCACGACGCCGAGCATCATTGAGAGGCAGCAT
GAGGAGGCAATTCTTCAGGCGTTTCAGAAAGGCTTCAAGGACGATGCCATCAGGGTCCGTCTTGCGGCGATGGAA
GCCTTCGCTTCTTTCTTCAGAACCATCAGCAAGAAGGTGCAAACCAAATACTTCCCGTTAATCTCGGACGTGCTG
AACATTCTACCTCCGATCAAAGAGTCCCAGGAGTCGGAGGATCTGAGCAAGGCACTCTTGGCCCTCATCGATCTC
GCCGAGTCAGCGCCTAAAATGTTCAAGCAATTATTCCACAATCTCGTTCAGTTCAACGTCTCCGTCATTCAAGAC
AAGGAGCTCGACAGCATTTGCAGGCAAAATGCCCTCGAACTCATGGCTACCTTCGCCGACTACGCACCCTCAATG
TGCAGAAAGGACGCCTCTTACACGAATGACATGGTCACGCAGTGTCTTAGCTTGATGACCGACCTCGGCGAAGAC
GACGACGATGCCGCGGAGTGGCTCGCCTCTGACGATCTTGATCAAGACGAAAGCGATCAAAATCACGTGGCTGGC
GAGCAGACCATGGACCGTCTCGCCAACAAGCTCGGCGGCCAGACTATCCTGGCTCCCACATTCAACTGGCTTCCC
CGGATGATGACGTCCATGGCTTGGAGGGATCGACACGCGGCTCTGATGGCCATCTCGGCCATTTCAGAGGGATGC
CGGGACCTCATGATTGGGGAGCTCAGCCAGGTGCTGGATTTGGTTGTGCCAGCCCTGCAGGACCCGCACCCGCGC
GTTCGCTGGGCTGGATGCAACGCGCTGGGCCAGATGAGCACTGATTTCGCTCCGAAAATGCAGACTGACTTTTTC
GACAGAGTGCTCAAGGCCATCATCCCTGTCCTGAACTCTCCCGCGGCGCGCGTCAAGTCTCACGCGGCTGCGGCC
TTGGTCAACTTCTGCGAGGAAGCAGAGAAGTCCGTTCTGGAGCCATACCTGGACGATCTCCTATCTCAACTGTTT
CAGCTGCTTCAAAGCGACAAGCGCTACGTTCAGGAGCAGGCCTTGTCGACCATCGCCACCATTGCCGATGCGGCT
GAGGCAGCCTTTTCCAAGTATTACGACACGTTGATGCCTCTCCTCGTCAACGTGCTCCAGAACCAAAGCGAAAAG
GAATTTCGGCTTTTGCGCTCCAAGGCCATGGAATGTGCTACTCTCATCGCCCTGGCCGTCGGACGGGAACGGCTC
GCAGCCGATGCCATGACGCTCGTCAACCTCCTCGCCAACATACAGACCAGTATCACCGATGCCGATGACCCGCAG
GCGCAATATCTGATGCATTGCTGGGGCCGAATGTGCCGCGTGCTCGGCGCTGACTTCATGCCGTTTCTGGACAGC
GTCATGCCTCCCGTGCTGGAACTGGCCATGGCCAAAGCCGATATACAGTTGCTCGACGATGACGACCAAGCCGAG
CAGATCAATGGTGAGGAGGGCTGGGAGTTCGTCCCGCTCAAGGGCAAAATGATTGGTATTCGGACAAGTACCATG
GATGACAAGCACATGGCCATTGAGCTCTTGCTCGTCTATGCTCAGACCCTCGAGGGTTCGTTTGCGCCGTTTGTG
GCCAACATCATGGAGAAAATTGCCCTCCCTGGCCTTGCCTTCTTCTTCCACGATCCTACCCGTTACATCTCTGCG
AAACTGGTCCCCTACCTCTTGAACTCGTACAAGAAGGCTTTCGGTTGCCCCTCCAACGAACTTGCCGGTCTCTGG
CACTTGACTGTGGAGAAGCTGTTGGAGGTCTTGACGGCTGAGCCATCGATCGAGACGCTCGCGGTCATGTACCAA
TGCTTCTACGAGTCCATGCAGGTGATTGGCAGAGACTGCCTCAGCCTTGAATACATGAACCGGTTCATCGACGCG
GTTCATTCCACACTGGAGGACTACCAGGACAGGGTCGCCCAGCGTGCCGAGGATAAGGAGGATGCGACGGCTGAC
GATGTCGAAGACGAGGCCGAGGAGACTCTGATGGCCATCGAAGACGATCAAACTCTCTTATCGGACATGAATAAG
GCATTTCATTCCATTTTTAGGCATCACGGCGCGGCTTTCCTACCGGCTTGGGAGCGGCTCATGTCGACATATCAA
GGGTTTCTAGCGTCCTCTGACTCGACTCAGCGACAATGGGGGCTCTGCATCGTGGATGACGTGCTGGAGTACTGC
GGGCCCGAGAGCCATCGGTATGCCAACTGCATTTCGCAACCTCTCATCGACGGCTGCAGGGACACGTCACCCGCC
ATCAGGCAGGCCGCTGCTTATGGTATCGGCGTTGCGGCTCATCGCGGCGGAGCACCCTGGTCTCAGTTCCTGGGA
GGGTCAGTGCCGTTTCTGTTCCAGATAACACAGGTGCCCGATGCCAGAAACGAGGACAACGTCTACGCTACGGAG
AACGCATGCGCTGCCTTGGCGAAAATTTTGCACTACAATTCTGGCAGCGTTGCAAACGTCCAAGCTGCGATTACG
CAGTGGATAGACACGTTACCGGTGATCAACGATGAAGAGGCGGCGCCGTATGCCTATGCCTATCTGGCCGAGCTT
ATTGATCAACGCCACCCTGCGGTCATGAACCAAGGCAGCAAGCTGTTCGTGTTGATCGCCCAGGCTCTCGAAGCC
GAGACTCTTCAGGGGCAGACAGCCACGAAAGTGGCAGTAGCCACGAAAGTGCTACTCACAAGTGCCAACGTGGAC
CCGATGCCGCTGCTCCAGCAGTTCTCGCAAGACTCGCAGCGAACAATTATGGGGTACTTCAGCTAG
Gene >Ophio5|4974
ATGTCTTTGCTCTCTGCCGACGTCCACACCCAACTAACCCAGCTCCTCCAAGCCTTGCAGTCCTCCGATAATGAC
ATTCGCTCCCAGGCTGAGGAGCATCTCCAGAAGAACTGGACAAGCACTCGCCCCGAAGTCCTGTTGATGGGTCTT
GTCGAGCAGATCCAAGGCGCAGACGATAATGCCGTGAGAGCCCTTTCCTCTTCGTCCTTTTCATTTGGTCATCTG
CGTTCTTCCAGTCGAGCTAACGCGTCGACTACAGACTCGTTCCTTTGCTGCTGTCATATTTCGTCGCATCTCGTC
CAAAACACGAAAGATCGAGACGGGCGAGAATGTCGACATTTTCTACTCTATACCAAGAAACCAAGCCGCCGTCAT
TCGTCAGAAGCTTCTTGAGACTCTTGCAACTGAGGAGGATCGTGCGGTCCGCAACAAGATCAGTGACGCCGTTGC
CGAGGTTGCGCGGCAGTACGCCGATAACAGTCAGTCGTTGATATCTCCCATCTTCTCGGCGTTGCTAATTCTTGC
ATCTCTTAAGATGATACTTGGCCTGAGCTTCTTGGCGCCCTTTTCCAGCTCAGTCAAGCGCCCGAACCCGAAAAA
CGCGACAACGCCTTCCGCGTCTTCACCACGACGCCGAGCATCATTGAGAGGCAGCATGAGGAGGCAATTCTTCAG
GCGTTTCAGAAAGGCTTCAAGGACGATGCCATCAGGGTACGTACATTAATTGTCACTGTCTGTACACGTGTGCCA
TTCGCTAAGCGGCCTCTCCAGGTCCGTCTTGCGGCGATGGAAGCCTTCGCTTCTTTCTTCAGAACCATCAGCAAG
AAGGTGCAAACCAAATACTTCCCGTTAATCTCGGACGTGCTGAACATTCTACCTCCGATCAAAGAGTCCCAGGAG
TCGGAGGATCTGAGCAAGGCACTCTTGGCCCTCATCGATCTCGCCGAGTCAGCGCCTAAAATGTTCAAGCAATTA
TTCCACAATCTCGTTCAGTTCAACGTCTCCGTCATTCAAGACAAGGAGCTCGACAGCATTTGCAGGCAAAATGCC
CTCGAACTCATGGCTACCTTCGCCGACTACGCACCCTCAATGTGCAGAAAGGACGCCTCTTACACGAATGACATG
GTCACGCAGTGTCTTAGCTTGATGACCGACCTCGGCGAAGACGACGACGATGCCGCGGAGTGGCTCGCCTCTGAC
GATGTGAGTACATGACCAAGCCGTCACTGCAGAATACTACTCACACGTCTGTAGCTTGATCAAGACGAAAGCGAT
CAAAATCACGTGGCTGGCGAGCAGACCATGGACCGTCTCGCCAACAAGCTCGGCGGCCAGACTATCCTGGCTCCC
ACATTCAACTGGCTTCCCCGGATGATGACGTCCATGGCTTGGAGGGATCGACACGCGGCTCTGATGGCCATCTCG
GCCATTTCAGAGGGATGCCGGGACCTCATGATTGGGGAGCTCAGCCAGGTGCTGGATTTGGTTGTGCCAGCCCTG
CAGGACCCGCACCCGCGCGTTCGCTGGGCTGGATGCAACGCGCTGGGCCAGATGAGCACTGATTTCGCTCCGAAA
ATGCAGACTGACTTTTTCGACAGAGTGCTCAAGGCCATCATCCCTGTCCTGAACTCTCCCGCGGCGCGCGTCAAG
TCTCACGCGGCTGCGGCCTTGGTCAACTTCTGCGAGGAAGCAGAGAAGTCCGTTCTGGAGCCATACCTGGACGAT
CTCCTATCTCAACTGTTTCAGCTGCTTCAAAGCGACAAGCGCTACGTTCAGGAGCAGGCCTTGTCGACCATCGCC
ACCATTGCCGATGCGGCTGAGGCAGCCTTTTCCAAGTATTACGACACGTTGATGCCTCTCCTCGTCAACGTGCTC
CAGAACCAAAGCGAAAAGGAATTTCGGCTTTTGCGCTCCAAGGCCATGGAATGTGCTACTCTCATCGCCCTGGCC
GTCGGACGGGAACGGCTCGCAGCCGATGCCATGACGCTCGTCAACCTCCTCGCCAACATACAGACCAGTATCACC
GATGCCGATGACCCGCAGGCGCAATATCTGATGCATTGCTGGGGCCGAATGTGCCGCGTGCTCGGCGCTGACTTC
ATGCCGTTTCTGGACAGCGTCATGCCTCCCGTGCTGGAACTGGCCATGGCCAAAGCCGATATACAGTTGCTCGAC
GATGACGACCAAGCCGAGCAGATCAATGGTGAGGAGGGCTGGGAGTTCGTCCCGCTCAAGGGCAAAATGATTGGT
ATTCGGACAAGTACCATGGATGACAAGCACATGGCCATTGAGCTCTTGCTCGTCTATGCTCAGACCCTCGAGGGT
TCGTTTGCGCCGTTTGTGGCCAACATCATGGAGAAAATTGCCCTCCCTGGCCTTGCCTTCTTCTTCCACGATCCT
ACCCGTTACATCTCTGCGAAACTGGTCCCCTACCTCTTGAACTCGTACAAGAAGGCTTTCGGTTGCCCCTCCAAC
GAACTTGCCGGTCTCTGGCACTTGACTGTGGAGAAGCTGTTGGAGGTCTTGACGGCTGAGCCATCGATCGAGACG
CTCGCGGTCATGTACCAATGCTTCTACGAGTCCATGCAGGTGATTGGCAGAGACTGCCTCAGCCTTGAATACATG
AACCGGTTCATCGACGCGGTTCATTCCACACTGGAGGACTACCAGGACAGGGTCGCCCAGCGTGCCGAGGATAAG
GAGGATGCGACGGCTGACGATGTCGAAGACGAGGCCGAGGAGACTCTGATGGCCATCGAAGACGATCAAACTCTC
TTATCGGACATGAATAAGGCATTTCATTCCATTTTTAGGCATCACGGCGCGGCTTTCCTACCGGCTTGGGAGCGG
CTCATGTCGACATATCAAGGGTTTCTAGCGTCCTCTGACTCGACTCAGCGACAATGGGGGCTCTGCATCGTGGAT
GACGTGCTGGAGTACTGCGGGCCCGAGAGCCATCGGTATGCCAACTGCATTTCGCAACCTCTCATCGACGGCTGC
AGGGACACGTCACCCGCCATCAGGCAGGCCGCTGCTTATGGTATCGGCGTTGCGGCTCATCGCGGCGGAGCACCC
TGGTCTCAGTTCCTGGGAGGGTCAGTGCCGTTTCTGTTCCAGATAACACAGGTGCCCGATGCCAGAAACGAGGAC
AACGTCTACGCTACGGAGAACGCATGCGCTGCCTTGGCGAAAATTTTGCACTACAATTCTGGCAGCGTTGCAAAC
GTCCAAGCTGCGATTACGCAGTGGATAGACACGTTACCGGTGATCAACGATGAAGAGGCGGCGCCGTATGCCTAT
GCCTATCTGGCCGAGCTTATTGATCAGTGAGTGTTGGAGACATTGCCCCAACCCCGTGAGCGGAGGAAATCAGCT
AACTCGTGATATCAGACGCCACCCTGCGGTCATGAACCAAGGCAGCAAGCTGTTCGTGTTGATCGCCCAGGCTCT
CGAAGCCGAGACTCTTCAGGGGCAGACAGCCACGAAAGTGGCAGTAGCCACGAAAGTGCTACTCACAAGTGCCAA
CGTGGACCCGATGCCGCTGCTCCAGCAGTTCTCGCAAGACTCGCAGCGAACAATTATGGGGTACTTCAGCTAG

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