© 2023 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Ophio5|3525 |
| Gene name | |
| Location | scaffold_28:21296..23126 |
| Strand | + |
| Gene length (bp) | 1830 |
| Transcript length (bp) | 1656 |
| Coding sequence length (bp) | 1653 |
| Protein length (aa) | 551 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF00884 | Sulfatase | Sulfatase | 8.7E-56 | 26 | 369 |
| PF12411 | Choline_sulf_C | Choline sulfatase enzyme C terminal | 3.9E-26 | 481 | 532 |
| PF01663 | Phosphodiest | Type I phosphodiesterase / nucleotide pyrophosphatase | 3.9E-08 | 31 | 314 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O69787|BETC_RHIME | Choline-sulfatase OS=Rhizobium meliloti (strain 1021) GN=betC PE=1 SV=2 | 25 | 533 | 7.0E-147 |
| sp|Q5ZK90|ARSK_CHICK | Arylsulfatase K OS=Gallus gallus GN=ARSK PE=2 SV=1 | 17 | 443 | 4.0E-35 |
| sp|Q0TUK6|SULF_CLOP1 | Arylsulfatase OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) GN=CPF_0221 PE=1 SV=1 | 25 | 442 | 7.0E-34 |
| sp|Q148F3|ARSK_BOVIN | Arylsulfatase K OS=Bos taurus GN=ARSK PE=2 SV=1 | 26 | 493 | 9.0E-34 |
| sp|Q08CJ7|ARSK_DANRE | Arylsulfatase K OS=Danio rerio GN=arsk PE=2 SV=1 | 25 | 493 | 1.0E-33 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O69787|BETC_RHIME | Choline-sulfatase OS=Rhizobium meliloti (strain 1021) GN=betC PE=1 SV=2 | 25 | 533 | 7.0E-147 |
| sp|Q5ZK90|ARSK_CHICK | Arylsulfatase K OS=Gallus gallus GN=ARSK PE=2 SV=1 | 17 | 443 | 4.0E-35 |
| sp|Q0TUK6|SULF_CLOP1 | Arylsulfatase OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) GN=CPF_0221 PE=1 SV=1 | 25 | 442 | 7.0E-34 |
| sp|Q148F3|ARSK_BOVIN | Arylsulfatase K OS=Bos taurus GN=ARSK PE=2 SV=1 | 26 | 493 | 9.0E-34 |
| sp|Q08CJ7|ARSK_DANRE | Arylsulfatase K OS=Danio rerio GN=arsk PE=2 SV=1 | 25 | 493 | 1.0E-33 |
| sp|P31447|YIDJ_ECOLI | Uncharacterized sulfatase YidJ OS=Escherichia coli (strain K12) GN=yidJ PE=3 SV=1 | 24 | 442 | 1.0E-33 |
| sp|Q32KJ2|ARSK_RAT | Arylsulfatase K OS=Rattus norvegicus GN=Arsk PE=2 SV=1 | 7 | 493 | 2.0E-33 |
| sp|Q8XNV1|SULF_CLOPE | Arylsulfatase OS=Clostridium perfringens (strain 13 / Type A) GN=CPE0231 PE=3 SV=1 | 25 | 442 | 2.0E-33 |
| sp|Q9D2L1|ARSK_MOUSE | Arylsulfatase K OS=Mus musculus GN=Arsk PE=2 SV=2 | 26 | 493 | 4.0E-33 |
| sp|Q0IHJ2|ARSK_XENLA | Arylsulfatase K OS=Xenopus laevis GN=arsk PE=2 SV=1 | 5 | 503 | 4.0E-33 |
| sp|Q32KH0|ARSK_CANLF | Arylsulfatase K OS=Canis lupus familiaris GN=ARSK PE=2 SV=1 | 26 | 473 | 2.0E-30 |
| sp|Q08890|IDS_MOUSE | Iduronate 2-sulfatase OS=Mus musculus GN=Ids PE=2 SV=3 | 27 | 377 | 2.0E-27 |
| sp|P50428|ARSA_MOUSE | Arylsulfatase A OS=Mus musculus GN=Arsa PE=1 SV=2 | 24 | 467 | 3.0E-27 |
| sp|Q6UWY0|ARSK_HUMAN | Arylsulfatase K OS=Homo sapiens GN=ARSK PE=1 SV=1 | 26 | 443 | 1.0E-26 |
| sp|P22304|IDS_HUMAN | Iduronate 2-sulfatase OS=Homo sapiens GN=IDS PE=1 SV=1 | 27 | 397 | 2.0E-26 |
| sp|Q32KJ6|GALNS_RAT | N-acetylgalactosamine-6-sulfatase OS=Rattus norvegicus GN=Galns PE=1 SV=1 | 26 | 387 | 4.0E-22 |
| sp|Q8BFR4|GNS_MOUSE | N-acetylglucosamine-6-sulfatase OS=Mus musculus GN=Gns PE=1 SV=1 | 25 | 404 | 5.0E-22 |
| sp|Q1LZH9|GNS_BOVIN | N-acetylglucosamine-6-sulfatase OS=Bos taurus GN=GNS PE=2 SV=1 | 25 | 444 | 1.0E-21 |
| sp|Q571E4|GALNS_MOUSE | N-acetylgalactosamine-6-sulfatase OS=Mus musculus GN=Galns PE=1 SV=2 | 26 | 387 | 2.0E-21 |
| sp|Q8WNQ7|GALNS_PIG | N-acetylgalactosamine-6-sulfatase OS=Sus scrofa GN=GALNS PE=2 SV=1 | 26 | 387 | 2.0E-21 |
| sp|P50426|GNS_CAPHI | N-acetylglucosamine-6-sulfatase OS=Capra hircus GN=GNS PE=2 SV=1 | 25 | 444 | 4.0E-21 |
| sp|P34059|GALNS_HUMAN | N-acetylgalactosamine-6-sulfatase OS=Homo sapiens GN=GALNS PE=1 SV=1 | 26 | 387 | 5.0E-21 |
| sp|Q08DD1|ARSA_BOVIN | Arylsulfatase A OS=Bos taurus GN=ARSA PE=2 SV=1 | 24 | 467 | 1.0E-20 |
| sp|Q32KH5|GALNS_CANLF | N-acetylgalactosamine-6-sulfatase OS=Canis lupus familiaris GN=GALNS PE=2 SV=1 | 26 | 413 | 2.0E-20 |
| sp|Q9VEX0|SULF1_DROME | Extracellular sulfatase SULF-1 homolog OS=Drosophila melanogaster GN=Sulf1 PE=1 SV=1 | 25 | 402 | 4.0E-20 |
| sp|P15586|GNS_HUMAN | N-acetylglucosamine-6-sulfatase OS=Homo sapiens GN=GNS PE=1 SV=3 | 25 | 404 | 5.0E-20 |
| sp|P51691|ARS_PSEAE | Arylsulfatase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=atsA PE=1 SV=3 | 25 | 443 | 9.0E-20 |
| sp|P15589|STS_RAT | Steryl-sulfatase OS=Rattus norvegicus GN=Sts PE=1 SV=2 | 23 | 389 | 2.0E-19 |
| sp|Q90XB6|SULF1_COTCO | Extracellular sulfatase Sulf-1 OS=Coturnix coturnix GN=SULF1 PE=1 SV=1 | 25 | 492 | 7.0E-18 |
| sp|Q9C0V7|YHJ2_SCHPO | Uncharacterized sulfatase PB10D8.02c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBPB10D8.02c PE=3 SV=1 | 19 | 445 | 1.0E-17 |
| sp|Q8IWU6|SULF1_HUMAN | Extracellular sulfatase Sulf-1 OS=Homo sapiens GN=SULF1 PE=1 SV=1 | 25 | 386 | 4.0E-17 |
| sp|Q60HH5|ARSE_MACFA | Arylsulfatase E OS=Macaca fascicularis GN=ARSE PE=2 SV=1 | 24 | 428 | 6.0E-17 |
| sp|P50429|ARSB_MOUSE | Arylsulfatase B OS=Mus musculus GN=Arsb PE=1 SV=3 | 26 | 382 | 9.0E-17 |
| sp|Q8K007|SULF1_MOUSE | Extracellular sulfatase Sulf-1 OS=Mus musculus GN=Sulf1 PE=2 SV=1 | 25 | 386 | 5.0E-16 |
| sp|P50430|ARSB_RAT | Arylsulfatase B OS=Rattus norvegicus GN=Arsb PE=2 SV=2 | 9 | 382 | 1.0E-15 |
| sp|Q8VI60|SULF1_RAT | Extracellular sulfatase Sulf-1 OS=Rattus norvegicus GN=Sulf1 PE=1 SV=1 | 25 | 386 | 3.0E-15 |
| sp|Q32KJ9|ARSG_RAT | Arylsulfatase G OS=Rattus norvegicus GN=Arsg PE=2 SV=1 | 25 | 444 | 3.0E-15 |
| sp|Q9X759|ATSA_KLEPN | Arylsulfatase OS=Klebsiella pneumoniae GN=atsA PE=1 SV=1 | 25 | 470 | 1.0E-14 |
| sp|P50473|ARS_STRPU | Arylsulfatase OS=Strongylocentrotus purpuratus PE=2 SV=1 | 24 | 378 | 1.0E-14 |
| sp|P14000|ARS_HEMPU | Arylsulfatase OS=Hemicentrotus pulcherrimus PE=1 SV=1 | 25 | 418 | 2.0E-14 |
| sp|P15289|ARSA_HUMAN | Arylsulfatase A OS=Homo sapiens GN=ARSA PE=1 SV=3 | 26 | 126 | 8.0E-14 |
| sp|P77318|YDEN_ECOLI | Uncharacterized sulfatase YdeN OS=Escherichia coli (strain K12) GN=ydeN PE=3 SV=2 | 15 | 393 | 2.0E-13 |
| sp|P51688|SPHM_HUMAN | N-sulphoglucosamine sulphohydrolase OS=Homo sapiens GN=SGSH PE=1 SV=1 | 24 | 389 | 3.0E-13 |
| sp|P08842|STS_HUMAN | Steryl-sulfatase OS=Homo sapiens GN=STS PE=1 SV=2 | 23 | 126 | 4.0E-13 |
| sp|P15848|ARSB_HUMAN | Arylsulfatase B OS=Homo sapiens GN=ARSB PE=1 SV=1 | 17 | 382 | 5.0E-13 |
| sp|Q21376|SULF1_CAEEL | Putative extracellular sulfatase Sulf-1 homolog OS=Caenorhabditis elegans GN=sul-1 PE=3 SV=1 | 24 | 399 | 7.0E-13 |
| sp|Q3TYD4|ARSG_MOUSE | Arylsulfatase G OS=Mus musculus GN=Arsg PE=2 SV=1 | 25 | 434 | 2.0E-12 |
| sp|Q96EG1|ARSG_HUMAN | Arylsulfatase G OS=Homo sapiens GN=ARSG PE=1 SV=1 | 23 | 444 | 2.0E-12 |
| sp|P33727|ARSB_FELCA | Arylsulfatase B OS=Felis catus GN=ARSB PE=2 SV=1 | 26 | 382 | 8.0E-12 |
| sp|Q5FYA8|ARSH_HUMAN | Arylsulfatase H OS=Homo sapiens GN=ARSH PE=2 SV=1 | 24 | 126 | 3.0E-11 |
| sp|P15289|ARSA_HUMAN | Arylsulfatase A OS=Homo sapiens GN=ARSA PE=1 SV=3 | 272 | 453 | 4.0E-11 |
| sp|P51690|ARSE_HUMAN | Arylsulfatase E OS=Homo sapiens GN=ARSE PE=1 SV=2 | 15 | 126 | 4.0E-11 |
| sp|P20713|ATSA_ENTAE | Arylsulfatase OS=Enterobacter aerogenes GN=atsA PE=1 SV=1 | 25 | 382 | 6.0E-11 |
| sp|Q32KI9|ARSI_MOUSE | Arylsulfatase I OS=Mus musculus GN=Arsi PE=2 SV=1 | 9 | 386 | 8.0E-11 |
| sp|Q32KH8|ARSH_CANLF | Arylsulfatase H OS=Canis lupus familiaris GN=ARSH PE=2 SV=1 | 24 | 125 | 2.0E-10 |
| sp|Q32KJ8|ARSI_RAT | Arylsulfatase I OS=Rattus norvegicus GN=Arsi PE=2 SV=1 | 27 | 386 | 4.0E-10 |
| sp|P51689|ARSD_HUMAN | Arylsulfatase D OS=Homo sapiens GN=ARSD PE=1 SV=2 | 18 | 125 | 6.0E-10 |
| sp|Q32KH7|ARSI_CANLF | Arylsulfatase I OS=Canis lupus familiaris GN=ARSI PE=2 SV=2 | 27 | 386 | 8.0E-10 |
| sp|P50427|STS_MOUSE | Steryl-sulfatase OS=Mus musculus GN=Sts PE=1 SV=1 | 27 | 126 | 1.0E-09 |
| sp|P50427|STS_MOUSE | Steryl-sulfatase OS=Mus musculus GN=Sts PE=1 SV=1 | 272 | 388 | 2.0E-09 |
| sp|Q5FYB1|ARSI_HUMAN | Arylsulfatase I OS=Homo sapiens GN=ARSI PE=1 SV=1 | 27 | 386 | 2.0E-09 |
| sp|P54793|ARSF_HUMAN | Arylsulfatase F OS=Homo sapiens GN=ARSF PE=1 SV=4 | 25 | 125 | 9.0E-09 |
| sp|Q32KH9|ARSG_CANLF | Arylsulfatase G OS=Canis lupus familiaris GN=ARSG PE=2 SV=1 | 23 | 126 | 6.0E-08 |
| sp|P54793|ARSF_HUMAN | Arylsulfatase F OS=Homo sapiens GN=ARSF PE=1 SV=4 | 248 | 402 | 1.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0008484 | sulfuric ester hydrolase activity | Yes |
| GO:0016787 | hydrolase activity | No |
| GO:0003824 | catalytic activity | No |
| GO:0003674 | molecular_function | No |
| GO:0016788 | hydrolase activity, acting on ester bonds | No |
| Localizations | Signals | Cytoplasm | Nucleus | Extracellular | Cell membrane | Mitochondrion | Plastid | Endoplasmic reticulum | Lysosome vacuole | Golgi apparatus | Peroxisome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytoplasm | Nuclear export signal | 0.7018 | 0.3847 | 0.0818 | 0.1627 | 0.3078 | 0.0395 | 0.0883 | 0.1739 | 0.1856 | 0.0032 |
| Orthofinder run ID | 4 |
| Orthogroup | 2433 |
| Change Orthofinder run |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Ophio5|3525 MSPDLNSLPASAPLLSPPKGPDGSRPNILYIMADQLAAPQLAMYNSESQIKTPNLDRLAAGSVQFDSAYCPSPLC APSRMSMITGLLPMKIGAFDNAAQISSEIPTYAHYLRSRGYHTALAGKMHFVGDQLHGYEQRLTSDIYPADFGWA VNWDEPDARLEWYHNASSILQAGPCGRSNQLDYDEEVMFRSTQYLWDHVRQGPGKRPFALTVSLTHPHDPYTITK KYWDLYEGVDIALPKARIPKEKLDSHSKRLMHVSDLWDHDLTDDQIRRAKRAYYGSVSYVDDCIGRLLETLRDAG LTEDTVVIFSGDHGDMLGERGLWYKMSYFESSVRVPLLVNYPRWFEPRHVSQNVSTLDLLPTICDLIGVKPAPYL PMDGLSMLPHLMGRDGGHDTVLAEYTGEGTVRPIMMIRRGPWKYITCPADEPQLYNLDDDPLELDNLARLRNVAP QTPAQAAAKAIFAQYDAEAKARWDFDAITAEVLQSQRRRRLVWDALKQGTFTSWDFDPIDDGRTKYIRSTIPLDT LERRARYPFVDSKSYPCNKTVDSTRG |
| Coding | >Ophio5|3525 ATGTCTCCCGATCTCAACTCGCTGCCGGCTTCGGCGCCTCTCCTCAGCCCTCCCAAGGGCCCAGACGGCTCGCGG CCCAACATCCTCTACATCATGGCCGATCAACTGGCGGCGCCGCAGCTGGCCATGTACAACAGCGAGTCGCAGATC AAGACGCCGAATCTGGACCGTCTGGCGGCCGGGTCGGTGCAGTTTGATTCGGCATACTGCCCTTCGCCGCTCTGC GCTCCCTCTCGCATGAGCATGATTACCGGACTGCTTCCTATGAAGATCGGCGCCTTTGACAACGCGGCCCAGATC AGCTCCGAGATCCCGACGTATGCGCACTATTTGCGCTCTCGCGGTTATCATACCGCTCTCGCCGGCAAGATGCAC TTTGTCGGCGACCAGCTGCACGGCTACGAGCAGCGACTCACCAGCGACATCTATCCGGCTGACTTTGGCTGGGCG GTCAATTGGGACGAGCCCGATGCCCGGCTGGAGTGGTATCACAACGCCAGCTCTATCCTGCAGGCTGGTCCCTGT GGCCGCAGCAATCAGCTCGACTACGATGAGGAGGTCATGTTCCGCAGCACCCAGTATCTGTGGGACCATGTGCGT CAGGGGCCGGGGAAGCGGCCCTTTGCCCTGACGGTCTCCCTCACGCACCCTCACGACCCCTACACCATCACCAAA AAGTACTGGGACCTCTACGAAGGCGTCGACATCGCCCTGCCCAAGGCCCGCATCCCCAAGGAAAAGCTCGACTCG CACAGCAAGCGATTGATGCACGTCTCCGACCTCTGGGACCACGATCTGACCGACGACCAGATCCGACGGGCCAAG CGGGCCTACTACGGCTCCGTCAGCTACGTCGACGACTGCATCGGCCGTTTGCTCGAGACGCTGCGTGACGCCGGC CTGACGGAAGACACCGTCGTCATCTTCAGCGGCGACCACGGCGATATGCTCGGTGAGCGCGGGCTCTGGTACAAG ATGAGCTACTTCGAGTCGTCGGTGCGCGTGCCGCTGCTCGTCAACTATCCGCGCTGGTTCGAGCCCCGTCACGTG TCGCAGAACGTCTCGACGCTCGACCTGCTGCCCACCATCTGCGACCTCATCGGCGTCAAGCCGGCCCCCTACCTG CCCATGGACGGACTCAGCATGCTGCCCCATCTCATGGGCCGCGACGGAGGCCACGACACCGTCCTGGCCGAGTAT ACGGGCGAGGGCACAGTCCGTCCCATCATGATGATCCGCCGAGGTCCCTGGAAGTACATTACCTGTCCGGCCGAC GAGCCCCAGCTGTACAACCTCGACGACGATCCGCTCGAGCTCGACAACTTGGCGCGCCTGCGAAACGTCGCGCCT CAGACCCCCGCCCAGGCCGCCGCCAAAGCCATCTTCGCCCAGTACGACGCCGAGGCCAAGGCCCGGTGGGACTTT GACGCCATCACCGCCGAGGTGCTGCAGTCGCAGCGCCGCCGTCGCCTGGTGTGGGACGCTCTGAAGCAGGGTACC TTTACCAGCTGGGACTTTGACCCCATCGACGACGGCCGGACAAAATACATTCGCTCCACGATCCCCCTCGACACG CTCGAGCGCCGCGCGCGCTACCCGTTTGTCGACTCCAAGTCGTACCCGTGCAACAAGACGGTCGACTCGACCCGC GGA |
| Transcript | >Ophio5|3525 ATGTCTCCCGATCTCAACTCGCTGCCGGCTTCGGCGCCTCTCCTCAGCCCTCCCAAGGGCCCAGACGGCTCGCGG CCCAACATCCTCTACATCATGGCCGATCAACTGGCGGCGCCGCAGCTGGCCATGTACAACAGCGAGTCGCAGATC AAGACGCCGAATCTGGACCGTCTGGCGGCCGGGTCGGTGCAGTTTGATTCGGCATACTGCCCTTCGCCGCTCTGC GCTCCCTCTCGCATGAGCATGATTACCGGACTGCTTCCTATGAAGATCGGCGCCTTTGACAACGCGGCCCAGATC AGCTCCGAGATCCCGACGTATGCGCACTATTTGCGCTCTCGCGGTTATCATACCGCTCTCGCCGGCAAGATGCAC TTTGTCGGCGACCAGCTGCACGGCTACGAGCAGCGACTCACCAGCGACATCTATCCGGCTGACTTTGGCTGGGCG GTCAATTGGGACGAGCCCGATGCCCGGCTGGAGTGGTATCACAACGCCAGCTCTATCCTGCAGGCTGGTCCCTGT GGCCGCAGCAATCAGCTCGACTACGATGAGGAGGTCATGTTCCGCAGCACCCAGTATCTGTGGGACCATGTGCGT CAGGGGCCGGGGAAGCGGCCCTTTGCCCTGACGGTCTCCCTCACGCACCCTCACGACCCCTACACCATCACCAAA AAGTACTGGGACCTCTACGAAGGCGTCGACATCGCCCTGCCCAAGGCCCGCATCCCCAAGGAAAAGCTCGACTCG CACAGCAAGCGATTGATGCACGTCTCCGACCTCTGGGACCACGATCTGACCGACGACCAGATCCGACGGGCCAAG CGGGCCTACTACGGCTCCGTCAGCTACGTCGACGACTGCATCGGCCGTTTGCTCGAGACGCTGCGTGACGCCGGC CTGACGGAAGACACCGTCGTCATCTTCAGCGGCGACCACGGCGATATGCTCGGTGAGCGCGGGCTCTGGTACAAG ATGAGCTACTTCGAGTCGTCGGTGCGCGTGCCGCTGCTCGTCAACTATCCGCGCTGGTTCGAGCCCCGTCACGTG TCGCAGAACGTCTCGACGCTCGACCTGCTGCCCACCATCTGCGACCTCATCGGCGTCAAGCCGGCCCCCTACCTG CCCATGGACGGACTCAGCATGCTGCCCCATCTCATGGGCCGCGACGGAGGCCACGACACCGTCCTGGCCGAGTAT ACGGGCGAGGGCACAGTCCGTCCCATCATGATGATCCGCCGAGGTCCCTGGAAGTACATTACCTGTCCGGCCGAC GAGCCCCAGCTGTACAACCTCGACGACGATCCGCTCGAGCTCGACAACTTGGCGCGCCTGCGAAACGTCGCGCCT CAGACCCCCGCCCAGGCCGCCGCCAAAGCCATCTTCGCCCAGTACGACGCCGAGGCCAAGGCCCGGTGGGACTTT GACGCCATCACCGCCGAGGTGCTGCAGTCGCAGCGCCGCCGTCGCCTGGTGTGGGACGCTCTGAAGCAGGGTACC TTTACCAGCTGGGACTTTGACCCCATCGACGACGGCCGGACAAAATACATTCGCTCCACGATCCCCCTCGACACG CTCGAGCGCCGCGCGCGCTACCCGTTTGTCGACTCCAAGTCGTACCCGTGCAACAAGACGGTCGACTCGACCCGC GGATGA |
| Gene | >Ophio5|3525 ATGTCTCCCGATCTCAACTCGCTGCCGGCTTCGGCGCCTCTCCTCAGCCCTCCCAAGGGCCCAGACGGCTCGCGG CCCAACATCCTCTACATCATGGCCGATCAACTGGCGGCGCCGCAGCTGGCCATGTACAACAGCGAGTCGCAGATC AAGACGCCGAATCTGGACCGTCTGGCGGCCGGGTCGGTGCAGTTTGATTCGGCATACTGCCCTTCGCCGCTCTGC GCTCCCTCTCGCATGAGCATGATTACCGGACTGCTTCCTATGAAGATCGGCGCCTTTGACAACGCGGCCCAGATC AGCTCCGAGATCCCGACGTATGCGCACTATTTGCGCTCTCGCGGTTATCATACCGCTCTCGCCGGCAAGATGCAC TTTGTCGGCGACCAGCTGCACGGCTACGAGCAGCGACTCACCAGCGACATCTATCCGGCTGACTTTGGCTGGGCG GTCAATTGGGACGAGCCCGATGCCCGGCTGGAGTGGTATCACAACGCCAGCTCTATCCTGCAGGCTGGTCCCTGT GGCCGCAGCAATCAGCTCGACTACGATGAGGAGGTCATGTTCCGCAGCACCCAGTATCTGTGGGACCATGTGCGT CAGGGGCCGGGGAAGCGGCCCTTTGCCCTGACGGTAGGACTCGACGTCGAGAGAGAGAGACGGAGACGGAGAGAA AGACGGAGAGAGACAGAGAGGAGAGAGATGGAATTGCTGACGCCCTTTTCCTCAGGTCTCCCTCACGCACCCTCA CGACCCCTACACCATCACCAAAAAGTACTGGGACCTCTACGAAGGCGTCGACATCGCCCTGCCCAAGGCCCGCAT CCCCAAGGAAAAGCTCGACTCGCACAGCAAGCGATTGATGCACGTCTCCGACCTCTGGGACCACGATCTGACCGA CGACCAGATCCGACGGGCCAAGCGGGCCTACTACGGCTCCGTCAGCTACGTCGACGACTGCATCGGCCGTTTGCT CGAGACGCTGCGTGACGCCGGCCTGACGGAAGACACCGTCGTCATCTTCAGCGGCGACCACGGCGATATGCTCGG TGAGCGCGGGCTCTGGTACAAGATGAGCTACTTCGAGTCGTCGGTGCGCGTGCCGCTGCTCGTCAACTATCCGCG CTGGTTCGAGCCCCGTCACGTGTCGCAGAACGTCTCGACGCTCGACCTGCTGCCCACCATCTGCGACCTCATCGG CGTCAAGCCGGCCCCCTACCTGCCCATGGACGGACTCAGCATGCTGCCCCATCTCATGGGCCGCGACGGAGGCCA CGACACCGTCCTGGCCGAGTATACGGGCGAGGGCACAGTCCGTCCCATCATGATGATCCGCCGAGGTCCCTGGAA GTACATTACCTGTCCGGCCGACGAGCCCCAGCTGTACAACCTCGACGACGATCCGCTCGAGCTCGACAACTTGGC GCGCCTGCGAAACGTCGCGCCTCAGACCCCCGCCCAGGCCGCCGCCAAAGCCATCTTCGCCCAGTACGACGCCGA GGCCAAGGCCCGGTGGGACTTTGACGCCATCACCGCCGAGGTGCTGCAGTCGCAGCGCCGCCGTCGCCTGGTGTG GGACGCTCTGAAGCAGGGTACCTTTACCAGCTGGGACTTTGACCCCATCGACGACGGCCGGACAAAGTAACTTCT TTTTGCCTTGCTTGTTGATGGTAGAGTGGGAGAGACGACCAATGGGCGCGGGCTGACACTACTTGCAGATACATT CGCTCCACGATCCCCCTCGACACGCTCGAGCGCCGCGCGCGCTACCCGTTTGTCGACTCCAAGTCGTACCCGTGC AACAAGACGGTCGACTCGACCCGCGGATGA |