© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Ophio5|256 |
| Gene name | |
| Location | scaffold_105:33491..34976 |
| Strand | + |
| Gene length (bp) | 1485 |
| Transcript length (bp) | 1485 |
| Coding sequence length (bp) | 1482 |
| Protein length (aa) | 494 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF08491 | SE | Squalene epoxidase | 2.4E-83 | 189 | 451 |
| PF01494 | FAD_binding_3 | FAD binding domain | 7.5E-05 | 14 | 73 |
| PF01266 | DAO | FAD dependent oxidoreductase | 1.4E-07 | 16 | 46 |
| PF13450 | NAD_binding_8 | NAD(P)-binding Rossmann-like domain | 3.6E-05 | 19 | 46 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q92206|ERG1_CANAL | Squalene monooxygenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG1 PE=3 SV=1 | 16 | 494 | 4.0E-103 |
| sp|Q9C1W3|ERG1_SCHPO | Probable squalene monooxygenase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg1 PE=3 SV=1 | 26 | 491 | 8.0E-102 |
| sp|O13306|ERG1_CANGA | Squalene monooxygenase OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=ERG1 PE=3 SV=2 | 16 | 491 | 8.0E-98 |
| sp|O81000|ERG15_ARATH | Squalene epoxidase 2, mitochondrial OS=Arabidopsis thaliana GN=SQE2 PE=1 SV=1 | 4 | 448 | 8.0E-92 |
| sp|P52019|ERG1_MOUSE | Squalene monooxygenase OS=Mus musculus GN=Sqle PE=2 SV=1 | 16 | 491 | 1.0E-90 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q92206|ERG1_CANAL | Squalene monooxygenase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=ERG1 PE=3 SV=1 | 16 | 494 | 4.0E-103 |
| sp|Q9C1W3|ERG1_SCHPO | Probable squalene monooxygenase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg1 PE=3 SV=1 | 26 | 491 | 8.0E-102 |
| sp|O13306|ERG1_CANGA | Squalene monooxygenase OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=ERG1 PE=3 SV=2 | 16 | 491 | 8.0E-98 |
| sp|O81000|ERG15_ARATH | Squalene epoxidase 2, mitochondrial OS=Arabidopsis thaliana GN=SQE2 PE=1 SV=1 | 4 | 448 | 8.0E-92 |
| sp|P52019|ERG1_MOUSE | Squalene monooxygenase OS=Mus musculus GN=Sqle PE=2 SV=1 | 16 | 491 | 1.0E-90 |
| sp|P32476|ERG1_YEAST | Squalene monooxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG1 PE=1 SV=2 | 16 | 491 | 2.0E-90 |
| sp|Q14534|ERG1_HUMAN | Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=1 SV=3 | 4 | 491 | 2.0E-89 |
| sp|Q9SM02|ERG14_ARATH | Squalene epoxidase 1 OS=Arabidopsis thaliana GN=SQE1 PE=1 SV=1 | 15 | 494 | 3.0E-89 |
| sp|P52020|ERG1_RAT | Squalene monooxygenase OS=Rattus norvegicus GN=Sqle PE=2 SV=1 | 14 | 491 | 5.0E-89 |
| sp|O48651|ERG1_PANGI | Squalene monooxygenase OS=Panax ginseng PE=2 SV=1 | 14 | 494 | 4.0E-88 |
| sp|Q75F69|ERG1_ASHGO | Squalene monooxygenase OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=ERG1 PE=3 SV=1 | 16 | 491 | 1.0E-86 |
| sp|Q8VYH2|ERG16_ARATH | Squalene epoxidase 3 OS=Arabidopsis thaliana GN=SQE3 PE=1 SV=1 | 29 | 494 | 1.0E-83 |
| sp|O65727|ERG11_BRANA | Squalene monooxygenase 1,1 OS=Brassica napus GN=SQP1,1 PE=2 SV=1 | 4 | 448 | 5.0E-67 |
| sp|O65404|ERG11_ARATH | Squalene epoxidase 5 OS=Arabidopsis thaliana GN=SQE5 PE=2 SV=2 | 15 | 448 | 1.0E-65 |
| sp|O65726|ERG12_BRANA | Squalene monooxygenase 1,2 OS=Brassica napus GN=SQP1,2 PE=2 SV=1 | 5 | 448 | 3.0E-61 |
| sp|O65402|ERG12_ARATH | Squalene epoxidase 6 OS=Arabidopsis thaliana GN=SQE6 PE=2 SV=1 | 15 | 492 | 2.0E-60 |
| sp|O65403|ERG13_ARATH | Squalene epoxidase 4 OS=Arabidopsis thaliana GN=SQE4 PE=2 SV=1 | 15 | 448 | 7.0E-51 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0050660 | flavin adenine dinucleotide binding | Yes |
| GO:0016491 | oxidoreductase activity | Yes |
| GO:0016021 | integral component of membrane | Yes |
| GO:0071949 | FAD binding | Yes |
| GO:0004506 | squalene monooxygenase activity | Yes |
| GO:0004497 | monooxygenase activity | No |
| GO:0043168 | anion binding | No |
| GO:0031224 | intrinsic component of membrane | No |
| GO:0043167 | ion binding | No |
| GO:0003674 | molecular_function | No |
| GO:0110165 | cellular anatomical entity | No |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | No |
| GO:0005488 | binding | No |
| GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | No |
| GO:1901363 | heterocyclic compound binding | No |
| GO:0005575 | cellular_component | No |
| GO:0000166 | nucleotide binding | No |
| GO:0097159 | organic cyclic compound binding | No |
| GO:0036094 | small molecule binding | No |
| GO:0003824 | catalytic activity | No |
| GO:1901265 | nucleoside phosphate binding | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 35 | 0.5 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 17 | 34 | 17 |
| 2 | 435 | 457 | 22 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Ophio5|256 MSPAARLRREHHHEADVVVVGAGVFGCAMAFALANQGRSVLLLERRMAEPDRIVGELLQPGGLAALRRLGLGHCV DGIDSIPCHGYHVVYRGQPVDIPYPPVGDDGDIACKWSGAASEGKRPQGRGFHHGRFIMRLRESCLAHDNITVVE TDVTKLVRGQHVGQILGVEARTLDKESAGERRSDYFFGNLTVIADGYDSKFRRQVVEEKPLVRSKFYALELIDCP LPREQFGLVVIGEAYPMVLYQIGARETRVLIDVPVGLPAASPAAGGVRGYIRNVAIPAMPAAVRPAAELALGDGK IPRSMPNSWLPASPQSADGLVLAGDAFNMRHPLTGGGMTVALHDAILLADLLHPDRLPRGLGDAQAVRTAVHTFY WRRKNCSSIINVLAQALYTLFAADDRQLRALQRGCFEYFRLGVTDGPCALLGGILHQPSVLAYHFFSVAFLAIWL NGVAVVGKGPYAPLRMPLVLVDAVLILSRASQVFLPLIWREGFR |
| Coding | >Ophio5|256 ATGTCTCCCGCAGCCCGCCTCCGACGCGAGCACCACCACGAAGCCGACGTCGTCGTCGTCGGCGCCGGCGTCTTC GGCTGCGCCATGGCCTTTGCCCTCGCGAACCAGGGCCGTTCCGTTCTTCTCCTTGAGCGTCGCATGGCGGAGCCC GATCGCATCGTCGGCGAGCTGCTTCAGCCAGGTGGATTGGCGGCCCTTCGTCGTCTGGGGCTGGGCCACTGCGTC GATGGCATCGATTCGATTCCCTGTCATGGTTATCACGTCGTCTATCGTGGTCAGCCTGTTGATATCCCCTATCCG CCTGTGGGTGATGACGGAGACATCGCCTGCAAGTGGTCCGGCGCCGCCTCGGAGGGGAAGAGGCCTCAGGGAAGA GGTTTCCATCATGGTCGCTTCATCATGCGCTTGAGGGAGTCGTGTCTCGCGCATGACAATATAACTGTCGTCGAG ACGGATGTGACGAAGCTGGTGCGCGGACAACACGTCGGCCAGATCCTCGGCGTCGAGGCTCGAACATTGGATAAG GAATCGGCCGGTGAGCGTCGAAGCGATTACTTCTTTGGAAACCTCACCGTCATCGCAGACGGCTACGACTCCAAG TTCCGTCGTCAAGTGGTCGAGGAAAAGCCCCTGGTCCGCAGCAAATTCTACGCCCTCGAGCTCATCGACTGCCCC TTACCGCGCGAGCAATTCGGCCTCGTCGTCATCGGCGAAGCATACCCCATGGTCCTGTACCAGATCGGCGCCCGC GAGACGCGCGTCCTCATCGACGTGCCCGTCGGTCTTCCCGCCGCCTCTCCCGCTGCCGGCGGCGTCCGTGGCTAT ATCCGCAACGTTGCTATTCCCGCCATGCCGGCTGCTGTCCGACCGGCTGCCGAGCTCGCTCTCGGGGACGGCAAG ATCCCTCGCAGCATGCCCAATAGCTGGCTTCCCGCGTCGCCGCAGTCGGCAGACGGGCTCGTCCTCGCCGGCGAT GCCTTCAACATGCGTCATCCGCTCACCGGAGGCGGCATGACGGTCGCTCTCCACGATGCCATACTTCTCGCCGAC CTCTTGCACCCGGATCGGCTGCCCAGGGGCCTCGGCGACGCCCAAGCCGTTCGCACCGCCGTCCACACCTTCTAC TGGCGTCGCAAGAATTGCTCTTCCATCATCAACGTCCTCGCTCAAGCTCTCTACACCCTCTTCGCCGCCGATGAT CGCCAGCTGCGCGCCCTGCAGCGCGGCTGCTTCGAGTATTTCCGCCTGGGCGTGACCGACGGGCCCTGTGCCCTG CTCGGAGGCATCCTGCACCAGCCTTCCGTTCTGGCCTATCACTTTTTCAGCGTCGCCTTCCTCGCCATCTGGCTC AATGGCGTTGCCGTCGTCGGCAAGGGTCCGTATGCGCCGCTGAGGATGCCGCTTGTGCTCGTCGATGCGGTCCTG ATTCTTTCGAGGGCCAGTCAGGTCTTTCTGCCTCTCATATGGCGAGAGGGGTTCCGG |
| Transcript | >Ophio5|256 ATGTCTCCCGCAGCCCGCCTCCGACGCGAGCACCACCACGAAGCCGACGTCGTCGTCGTCGGCGCCGGCGTCTTC GGCTGCGCCATGGCCTTTGCCCTCGCGAACCAGGGCCGTTCCGTTCTTCTCCTTGAGCGTCGCATGGCGGAGCCC GATCGCATCGTCGGCGAGCTGCTTCAGCCAGGTGGATTGGCGGCCCTTCGTCGTCTGGGGCTGGGCCACTGCGTC GATGGCATCGATTCGATTCCCTGTCATGGTTATCACGTCGTCTATCGTGGTCAGCCTGTTGATATCCCCTATCCG CCTGTGGGTGATGACGGAGACATCGCCTGCAAGTGGTCCGGCGCCGCCTCGGAGGGGAAGAGGCCTCAGGGAAGA GGTTTCCATCATGGTCGCTTCATCATGCGCTTGAGGGAGTCGTGTCTCGCGCATGACAATATAACTGTCGTCGAG ACGGATGTGACGAAGCTGGTGCGCGGACAACACGTCGGCCAGATCCTCGGCGTCGAGGCTCGAACATTGGATAAG GAATCGGCCGGTGAGCGTCGAAGCGATTACTTCTTTGGAAACCTCACCGTCATCGCAGACGGCTACGACTCCAAG TTCCGTCGTCAAGTGGTCGAGGAAAAGCCCCTGGTCCGCAGCAAATTCTACGCCCTCGAGCTCATCGACTGCCCC TTACCGCGCGAGCAATTCGGCCTCGTCGTCATCGGCGAAGCATACCCCATGGTCCTGTACCAGATCGGCGCCCGC GAGACGCGCGTCCTCATCGACGTGCCCGTCGGTCTTCCCGCCGCCTCTCCCGCTGCCGGCGGCGTCCGTGGCTAT ATCCGCAACGTTGCTATTCCCGCCATGCCGGCTGCTGTCCGACCGGCTGCCGAGCTCGCTCTCGGGGACGGCAAG ATCCCTCGCAGCATGCCCAATAGCTGGCTTCCCGCGTCGCCGCAGTCGGCAGACGGGCTCGTCCTCGCCGGCGAT GCCTTCAACATGCGTCATCCGCTCACCGGAGGCGGCATGACGGTCGCTCTCCACGATGCCATACTTCTCGCCGAC CTCTTGCACCCGGATCGGCTGCCCAGGGGCCTCGGCGACGCCCAAGCCGTTCGCACCGCCGTCCACACCTTCTAC TGGCGTCGCAAGAATTGCTCTTCCATCATCAACGTCCTCGCTCAAGCTCTCTACACCCTCTTCGCCGCCGATGAT CGCCAGCTGCGCGCCCTGCAGCGCGGCTGCTTCGAGTATTTCCGCCTGGGCGTGACCGACGGGCCCTGTGCCCTG CTCGGAGGCATCCTGCACCAGCCTTCCGTTCTGGCCTATCACTTTTTCAGCGTCGCCTTCCTCGCCATCTGGCTC AATGGCGTTGCCGTCGTCGGCAAGGGTCCGTATGCGCCGCTGAGGATGCCGCTTGTGCTCGTCGATGCGGTCCTG ATTCTTTCGAGGGCCAGTCAGGTCTTTCTGCCTCTCATATGGCGAGAGGGGTTCCGGTGA |
| Gene | >Ophio5|256 ATGTCTCCCGCAGCCCGCCTCCGACGCGAGCACCACCACGAAGCCGACGTCGTCGTCGTCGGCGCCGGCGTCTTC GGCTGCGCCATGGCCTTTGCCCTCGCGAACCAGGGCCGTTCCGTTCTTCTCCTTGAGCGTCGCATGGCGGAGCCC GATCGCATCGTCGGCGAGCTGCTTCAGCCAGGTGGATTGGCGGCCCTTCGTCGTCTGGGGCTGGGCCACTGCGTC GATGGCATCGATTCGATTCCCTGTCATGGTTATCACGTCGTCTATCGTGGTCAGCCTGTTGATATCCCCTATCCG CCTGTGGGTGATGACGGAGACATCGCCTGCAAGTGGTCCGGCGCCGCCTCGGAGGGGAAGAGGCCTCAGGGAAGA GGTTTCCATCATGGTCGCTTCATCATGCGCTTGAGGGAGTCGTGTCTCGCGCATGACAATATAACTGTCGTCGAG ACGGATGTGACGAAGCTGGTGCGCGGACAACACGTCGGCCAGATCCTCGGCGTCGAGGCTCGAACATTGGATAAG GAATCGGCCGGTGAGCGTCGAAGCGATTACTTCTTTGGAAACCTCACCGTCATCGCAGACGGCTACGACTCCAAG TTCCGTCGTCAAGTGGTCGAGGAAAAGCCCCTGGTCCGCAGCAAATTCTACGCCCTCGAGCTCATCGACTGCCCC TTACCGCGCGAGCAATTCGGCCTCGTCGTCATCGGCGAAGCATACCCCATGGTCCTGTACCAGATCGGCGCCCGC GAGACGCGCGTCCTCATCGACGTGCCCGTCGGTCTTCCCGCCGCCTCTCCCGCTGCCGGCGGCGTCCGTGGCTAT ATCCGCAACGTTGCTATTCCCGCCATGCCGGCTGCTGTCCGACCGGCTGCCGAGCTCGCTCTCGGGGACGGCAAG ATCCCTCGCAGCATGCCCAATAGCTGGCTTCCCGCGTCGCCGCAGTCGGCAGACGGGCTCGTCCTCGCCGGCGAT GCCTTCAACATGCGTCATCCGCTCACCGGAGGCGGCATGACGGTCGCTCTCCACGATGCCATACTTCTCGCCGAC CTCTTGCACCCGGATCGGCTGCCCAGGGGCCTCGGCGACGCCCAAGCCGTTCGCACCGCCGTCCACACCTTCTAC TGGCGTCGCAAGAATTGCTCTTCCATCATCAACGTCCTCGCTCAAGCTCTCTACACCCTCTTCGCCGCCGATGAT CGCCAGCTGCGCGCCCTGCAGCGCGGCTGCTTCGAGTATTTCCGCCTGGGCGTGACCGACGGGCCCTGTGCCCTG CTCGGAGGCATCCTGCACCAGCCTTCCGTTCTGGCCTATCACTTTTTCAGCGTCGCCTTCCTCGCCATCTGGCTC AATGGCGTTGCCGTCGTCGGCAAGGGTCCGTATGCGCCGCTGAGGATGCCGCTTGTGCTCGTCGATGCGGTCCTG ATTCTTTCGAGGGCCAGTCAGGTCTTTCTGCCTCTCATATGGCGAGAGGGGTTCCGGTGA |