Fungal Genomics

at Utrecht University

General Properties

Protein ID	Ophio5\|1785
Gene name
Location	scaffold_168:20525..23853
Strand	+
Gene length (bp)	3328
Transcript length (bp)	3222
Coding sequence length (bp)	3219
Protein length (aa)	1073

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF07993	NAD_binding_4	Male sterility protein	1.9E-26	701	932
PF00501	AMP-binding	AMP-binding enzyme	5.7E-26	25	360
PF01370	Epimerase	NAD dependent epimerase/dehydratase family	8.9E-09	699	939

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q6RKB1\|CAR_NOCIO	Carboxylic acid reductase OS=Nocardia iowensis GN=car PE=1 SV=1	697	1024	9.0E-16
sp\|Q70LM4\|LGRD_BREPA	Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis GN=lgrD PE=1 SV=1	697	1041	4.0E-14
sp\|O74298\|LYS2_PENCH	L-2-aminoadipate reductase large subunit OS=Penicillium chrysogenum GN=lys2 PE=3 SV=1	387	1016	4.0E-12
sp\|Q4WAZ9\|NRP14_ASPFU	Nonribosomal peptide synthetase 14 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=NRPS14 PE=2 SV=2	698	991	2.0E-08
sp\|B2HN69\|CAR_MYCMM	Carboxylic acid reductase OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=car PE=1 SV=1	649	920	2.0E-08

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q6RKB1\|CAR_NOCIO	Carboxylic acid reductase OS=Nocardia iowensis GN=car PE=1 SV=1	697	1024	9.0E-16
sp\|Q70LM4\|LGRD_BREPA	Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis GN=lgrD PE=1 SV=1	697	1041	4.0E-14
sp\|O74298\|LYS2_PENCH	L-2-aminoadipate reductase large subunit OS=Penicillium chrysogenum GN=lys2 PE=3 SV=1	387	1016	4.0E-12
sp\|Q4WAZ9\|NRP14_ASPFU	Nonribosomal peptide synthetase 14 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=NRPS14 PE=2 SV=2	698	991	2.0E-08
sp\|B2HN69\|CAR_MYCMM	Carboxylic acid reductase OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=car PE=1 SV=1	649	920	2.0E-08
sp\|Q54TW0\|PKS18_DICDI	Probable polyketide synthase 18 OS=Dictyostelium discoideum GN=pks18 PE=2 SV=1	660	930	4.0E-07
sp\|P37693\|HETM_NOSS1	Polyketide synthase HetM OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=hetM PE=3 SV=1	692	1003	2.0E-06

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 30	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	242	264	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in De Bekker et al., 2017.

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
SC16a	Pure fungal culture	0.0	0.0	0.0
CcL	In ants, during behavior modification	0.0	0.0	0.0
CcD	In ants, recently dead	0.0	0.0	0.0

Differential expression

Label1	Label2	Q-value	Significant difference
SC16a	CcL	1.0	no
SC16a	CcD	1.0	no
CcL	CcD	1.0	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophio5\|1785 MPAATEQRYSTGPAYGHRLPVNIVDEVAATDPTRPFVFAPRSNKPEDGWAPITYEQVARAVNHVAHIIAQTVKSG SEEAFPTLAYVGPNDIRYGIIMLACIKAGCKALFVAPRNSSEIQQSLLEKTACGYFWYAESFHAIVQPWLQLQER PMQVTMVPSPEKWLSSDPAPFPYSRPFDEARFDPLVTLHTSGSTGTPKPIIVRQGTVAIADEFRNLPEYQDAEFL WKGWASRSNRMFMPMPLFHTAGLTAFLVVLTIFYGVPLALGIPDQPLSADLVERCLRCSHADSAFLPPSIVEELS STEKSMDTLKKLNFVGFGGGNLSQAAGDRLVKQGVMLSNGISPTENLPYAIYWQPSPEDWQYFIFNSELMGAVWH MKDEKEGIYELIISRKDATDPRDQPVFYTFPNATEWSTGDLYRAHPYLPDHWAFHGRADDIIVFSNGEKLNPITI ENTIMGHPAVKGALVVGQDRFQPALIVEPMHDPKDDQEAKALLEDIWELIDEANRVAVRHGRIVRQLISISDPGI PFFRASKGTIQRSPTIRAYQKHIDGIYERAEATDMQDVTPLDFTSEETLGNSIIRLINDHVGVQIVETSTDLFSL GIDSLQVLRISKILGASTGAAGVALDPNVIAPHLVYSNPSPQYLASYLFSASKDVSNAKKEETERETQLLETLIS KYTKDLPASKAYDKPAPLDDDQTILLTGSTGSLGSYLLERLCTLACVKKILVLNRGQDGGKSRQGSGNEARGLST DFAKVEFLGTDLSLPDLGLGEAKYGELLVSVDRIIHNAWPVNLNIMSVMPFEPHIRGVRHLVDFSTKAVKRVPIL FISSIGTASAWQSTKYVPERALEDLSLANTGYGRSKLAASLILDSAVRYAGTAAASVRVGQIAGPRSQKGMWNKQ EYIPSMIASSLYLGMLPDNFGTGEEVDWMAIEDVTALILDVAGITTNTPVSAIDGYFHSVNPAKTTWGQLAGELL EYYSGRVRLVSFEEWVTAIEKSASTTTDISRNPAIKLLDLYKGMLQASRQGLSHVNFEMSRTMSRSRTVAQLGPI TADLLRNWCSQWGFESDAISLQA
Coding	>Ophio5\|1785 ATGCCTGCTGCAACGGAACAACGATACTCGACCGGACCTGCCTATGGGCATCGGTTGCCTGTCAACATTGTCGAC GAGGTTGCTGCAACGGACCCTACTCGTCCCTTCGTATTCGCCCCCCGATCTAATAAGCCTGAGGACGGCTGGGCG CCGATTACATATGAGCAGGTCGCCAGGGCAGTCAACCACGTAGCTCATATCATCGCGCAAACAGTGAAATCGGGT TCGGAAGAGGCATTCCCTACGTTGGCTTACGTTGGCCCAAATGACATCCGCTACGGAATCATCATGCTCGCTTGT ATCAAGGCAGGGTGCAAAGCCTTGTTCGTTGCACCTCGGAACAGTTCAGAGATTCAGCAGAGCCTATTGGAGAAG ACAGCCTGTGGCTACTTCTGGTATGCCGAGTCATTTCATGCCATCGTTCAGCCATGGCTTCAGCTCCAGGAGCGA CCGATGCAAGTCACTATGGTGCCGTCTCCGGAGAAATGGCTCAGCTCGGATCCGGCCCCGTTTCCTTACTCCCGG CCGTTCGACGAGGCCCGATTCGATCCGTTGGTGACCCTGCACACCAGCGGCTCGACAGGCACCCCGAAGCCGATC ATCGTGCGCCAGGGAACTGTTGCCATCGCAGACGAATTTCGAAACCTACCTGAATATCAGGATGCTGAGTTCCTG TGGAAAGGATGGGCATCTCGTTCCAACCGAATGTTCATGCCCATGCCGCTCTTCCACACCGCTGGCCTCACAGCC TTCCTCGTGGTCCTTACTATATTTTACGGGGTGCCACTCGCGTTGGGCATACCAGACCAGCCCCTCTCCGCTGAC TTGGTGGAGAGGTGCCTACGTTGTTCTCATGCCGACTCGGCATTCCTTCCGCCCTCGATTGTGGAGGAACTGAGC TCGACGGAGAAGAGCATGGATACACTCAAGAAGCTCAACTTTGTTGGCTTCGGTGGCGGAAACCTATCCCAGGCG GCCGGTGATAGACTTGTGAAGCAGGGGGTCATGCTTTCTAATGGCATCTCGCCAACAGAAAACCTTCCCTATGCC ATTTACTGGCAGCCTAGTCCCGAGGACTGGCAATACTTCATCTTCAATAGCGAGCTTATGGGGGCGGTTTGGCAC ATGAAAGACGAGAAAGAAGGCATTTACGAGCTGATCATCTCTCGAAAAGACGCGACGGATCCTCGAGATCAGCCG GTATTTTACACGTTTCCCAACGCCACCGAGTGGTCAACCGGAGATCTTTACAGAGCCCACCCTTATCTGCCCGAT CATTGGGCTTTCCACGGCCGGGCCGATGATATCATTGTCTTCTCGAATGGAGAGAAACTTAATCCAATCACAATC GAAAACACCATCATGGGGCATCCTGCTGTCAAAGGAGCCTTGGTTGTTGGGCAGGATAGGTTTCAACCCGCACTC ATCGTCGAGCCAATGCATGACCCAAAAGACGACCAAGAGGCAAAGGCATTGCTTGAAGATATATGGGAGCTGATT GATGAGGCAAACCGGGTGGCGGTCAGGCATGGCCGCATCGTTCGCCAGCTAATTTCCATCTCAGATCCTGGCATC CCATTCTTTCGGGCGTCAAAGGGTACTATACAGCGAAGTCCAACGATACGAGCCTACCAGAAGCATATTGATGGG ATTTACGAGCGCGCTGAAGCAACTGACATGCAAGATGTGACGCCACTGGACTTTACCAGCGAAGAAACACTAGGG AATTCCATCATTCGACTGATAAACGATCATGTTGGGGTGCAGATTGTTGAAACGAGCACAGACTTGTTCTCTCTC GGCATCGACTCGCTTCAGGTCTTACGGATATCAAAGATACTTGGTGCGAGCACCGGCGCCGCTGGAGTGGCATTG GATCCCAATGTAATTGCACCTCACTTGGTTTACTCGAACCCGTCACCGCAGTATCTCGCCTCTTACCTCTTCTCG GCATCCAAGGATGTAAGCAACGCAAAGAAGGAAGAGACTGAGCGGGAGACACAACTACTCGAGACTCTCATATCC AAGTACACCAAGGATCTCCCCGCCTCAAAGGCATACGATAAGCCCGCACCCCTTGACGATGACCAGACAATTCTT CTGACGGGCAGTACTGGCTCACTCGGTTCCTACCTTCTCGAAAGACTTTGCACATTGGCGTGCGTCAAGAAGATA CTTGTTCTCAATCGCGGTCAAGATGGCGGCAAGTCACGTCAAGGCTCTGGCAACGAGGCTCGAGGTTTGAGCACA GACTTTGCCAAGGTCGAGTTTCTCGGCACCGACCTTTCACTTCCAGATCTAGGTCTCGGTGAGGCAAAGTATGGA GAGCTTCTCGTGTCGGTGGATCGAATTATCCATAACGCATGGCCCGTCAACCTCAACATCATGAGCGTCATGCCC TTTGAACCACATATTCGCGGCGTGCGACACTTGGTCGACTTTTCAACCAAGGCCGTTAAGCGCGTCCCTATCCTC TTCATCTCCAGCATCGGCACAGCAAGCGCTTGGCAATCGACCAAATATGTCCCCGAACGTGCCCTTGAAGACTTG TCTCTCGCCAATACGGGCTACGGCCGCTCCAAGCTGGCTGCAAGTCTCATTCTGGACTCGGCAGTGCGATACGCC GGAACCGCTGCCGCGTCGGTCCGAGTGGGACAGATTGCCGGGCCACGAAGCCAGAAGGGCATGTGGAACAAGCAA GAGTATATACCGAGCATGATTGCCAGCTCTCTCTACCTTGGCATGCTGCCAGACAACTTTGGTACGGGTGAGGAG GTTGACTGGATGGCCATCGAAGACGTCACCGCTCTCATTCTCGACGTGGCCGGCATAACCACCAACACTCCCGTC TCAGCCATCGACGGCTACTTCCACAGCGTCAACCCGGCCAAGACAACATGGGGCCAGCTCGCAGGTGAGCTCCTA GAATACTACTCCGGAAGGGTACGGCTGGTCAGCTTCGAGGAATGGGTTACTGCCATTGAAAAGAGCGCGAGCACC ACTACGGATATATCGAGAAATCCTGCCATCAAGCTCCTCGACCTGTACAAGGGGATGCTGCAAGCCTCTCGCCAA GGGCTCAGTCACGTCAATTTCGAAATGTCGAGGACTATGAGCCGCAGCAGGACAGTGGCTCAGCTGGGCCCCATC ACTGCCGATCTGCTGAGGAATTGGTGCTCTCAGTGGGGGTTTGAGTCCGATGCGATCAGTTTGCAGGCC
Transcript	>Ophio5\|1785 ATGCCTGCTGCAACGGAACAACGATACTCGACCGGACCTGCCTATGGGCATCGGTTGCCTGTCAACATTGTCGAC GAGGTTGCTGCAACGGACCCTACTCGTCCCTTCGTATTCGCCCCCCGATCTAATAAGCCTGAGGACGGCTGGGCG CCGATTACATATGAGCAGGTCGCCAGGGCAGTCAACCACGTAGCTCATATCATCGCGCAAACAGTGAAATCGGGT TCGGAAGAGGCATTCCCTACGTTGGCTTACGTTGGCCCAAATGACATCCGCTACGGAATCATCATGCTCGCTTGT ATCAAGGCAGGGTGCAAAGCCTTGTTCGTTGCACCTCGGAACAGTTCAGAGATTCAGCAGAGCCTATTGGAGAAG ACAGCCTGTGGCTACTTCTGGTATGCCGAGTCATTTCATGCCATCGTTCAGCCATGGCTTCAGCTCCAGGAGCGA CCGATGCAAGTCACTATGGTGCCGTCTCCGGAGAAATGGCTCAGCTCGGATCCGGCCCCGTTTCCTTACTCCCGG CCGTTCGACGAGGCCCGATTCGATCCGTTGGTGACCCTGCACACCAGCGGCTCGACAGGCACCCCGAAGCCGATC ATCGTGCGCCAGGGAACTGTTGCCATCGCAGACGAATTTCGAAACCTACCTGAATATCAGGATGCTGAGTTCCTG TGGAAAGGATGGGCATCTCGTTCCAACCGAATGTTCATGCCCATGCCGCTCTTCCACACCGCTGGCCTCACAGCC TTCCTCGTGGTCCTTACTATATTTTACGGGGTGCCACTCGCGTTGGGCATACCAGACCAGCCCCTCTCCGCTGAC TTGGTGGAGAGGTGCCTACGTTGTTCTCATGCCGACTCGGCATTCCTTCCGCCCTCGATTGTGGAGGAACTGAGC TCGACGGAGAAGAGCATGGATACACTCAAGAAGCTCAACTTTGTTGGCTTCGGTGGCGGAAACCTATCCCAGGCG GCCGGTGATAGACTTGTGAAGCAGGGGGTCATGCTTTCTAATGGCATCTCGCCAACAGAAAACCTTCCCTATGCC ATTTACTGGCAGCCTAGTCCCGAGGACTGGCAATACTTCATCTTCAATAGCGAGCTTATGGGGGCGGTTTGGCAC ATGAAAGACGAGAAAGAAGGCATTTACGAGCTGATCATCTCTCGAAAAGACGCGACGGATCCTCGAGATCAGCCG GTATTTTACACGTTTCCCAACGCCACCGAGTGGTCAACCGGAGATCTTTACAGAGCCCACCCTTATCTGCCCGAT CATTGGGCTTTCCACGGCCGGGCCGATGATATCATTGTCTTCTCGAATGGAGAGAAACTTAATCCAATCACAATC GAAAACACCATCATGGGGCATCCTGCTGTCAAAGGAGCCTTGGTTGTTGGGCAGGATAGGTTTCAACCCGCACTC ATCGTCGAGCCAATGCATGACCCAAAAGACGACCAAGAGGCAAAGGCATTGCTTGAAGATATATGGGAGCTGATT GATGAGGCAAACCGGGTGGCGGTCAGGCATGGCCGCATCGTTCGCCAGCTAATTTCCATCTCAGATCCTGGCATC CCATTCTTTCGGGCGTCAAAGGGTACTATACAGCGAAGTCCAACGATACGAGCCTACCAGAAGCATATTGATGGG ATTTACGAGCGCGCTGAAGCAACTGACATGCAAGATGTGACGCCACTGGACTTTACCAGCGAAGAAACACTAGGG AATTCCATCATTCGACTGATAAACGATCATGTTGGGGTGCAGATTGTTGAAACGAGCACAGACTTGTTCTCTCTC GGCATCGACTCGCTTCAGGTCTTACGGATATCAAAGATACTTGGTGCGAGCACCGGCGCCGCTGGAGTGGCATTG GATCCCAATGTAATTGCACCTCACTTGGTTTACTCGAACCCGTCACCGCAGTATCTCGCCTCTTACCTCTTCTCG GCATCCAAGGATGTAAGCAACGCAAAGAAGGAAGAGACTGAGCGGGAGACACAACTACTCGAGACTCTCATATCC AAGTACACCAAGGATCTCCCCGCCTCAAAGGCATACGATAAGCCCGCACCCCTTGACGATGACCAGACAATTCTT CTGACGGGCAGTACTGGCTCACTCGGTTCCTACCTTCTCGAAAGACTTTGCACATTGGCGTGCGTCAAGAAGATA CTTGTTCTCAATCGCGGTCAAGATGGCGGCAAGTCACGTCAAGGCTCTGGCAACGAGGCTCGAGGTTTGAGCACA GACTTTGCCAAGGTCGAGTTTCTCGGCACCGACCTTTCACTTCCAGATCTAGGTCTCGGTGAGGCAAAGTATGGA GAGCTTCTCGTGTCGGTGGATCGAATTATCCATAACGCATGGCCCGTCAACCTCAACATCATGAGCGTCATGCCC TTTGAACCACATATTCGCGGCGTGCGACACTTGGTCGACTTTTCAACCAAGGCCGTTAAGCGCGTCCCTATCCTC TTCATCTCCAGCATCGGCACAGCAAGCGCTTGGCAATCGACCAAATATGTCCCCGAACGTGCCCTTGAAGACTTG TCTCTCGCCAATACGGGCTACGGCCGCTCCAAGCTGGCTGCAAGTCTCATTCTGGACTCGGCAGTGCGATACGCC GGAACCGCTGCCGCGTCGGTCCGAGTGGGACAGATTGCCGGGCCACGAAGCCAGAAGGGCATGTGGAACAAGCAA GAGTATATACCGAGCATGATTGCCAGCTCTCTCTACCTTGGCATGCTGCCAGACAACTTTGGTACGGGTGAGGAG GTTGACTGGATGGCCATCGAAGACGTCACCGCTCTCATTCTCGACGTGGCCGGCATAACCACCAACACTCCCGTC TCAGCCATCGACGGCTACTTCCACAGCGTCAACCCGGCCAAGACAACATGGGGCCAGCTCGCAGGTGAGCTCCTA GAATACTACTCCGGAAGGGTACGGCTGGTCAGCTTCGAGGAATGGGTTACTGCCATTGAAAAGAGCGCGAGCACC ACTACGGATATATCGAGAAATCCTGCCATCAAGCTCCTCGACCTGTACAAGGGGATGCTGCAAGCCTCTCGCCAA GGGCTCAGTCACGTCAATTTCGAAATGTCGAGGACTATGAGCCGCAGCAGGACAGTGGCTCAGCTGGGCCCCATC ACTGCCGATCTGCTGAGGAATTGGTGCTCTCAGTGGGGGTTTGAGTCCGATGCGATCAGTTTGCAGGCCTGA
Gene	>Ophio5\|1785 ATGCCTGCTGCAACGGAACAACGATACTCGACCGGACCTGCCTATGGGCATCGGTTGCCTGTCAACATTGTCGAC GAGGTTGCTGCAACGGACCCTACTCGTCCCTTCGTATTCGCCCCCCGATCTAATAAGCCTGAGGACGGCTGGGCG CCGATTACATATGAGCAGGTCGCCAGGGCAGTCAACCACGTAGCTCATATCATCGCGCAAACAGTGAAATCGGGT TCGGAAGAGGCATTCCCTACGTTGGCTTACGTTGGCCCAAATGACATCCGCTACGGAATCATCATGCTCGCTTGT ATCAAGGCAGGGTGCAAAGCCTTGTTCGTTGCACCTCGGAACAGTTCAGAGATTCAGCAGAGCCTATTGGAGAAG ACAGCCTGTGGCTACTTCTGGTATGCCGAGTCATTTCATGCCATCGTTCAGCCATGGCTTCAGCTCCAGGAGCGA CCGATGCAAGTCACTATGGTGCCGTCTCCGGAGAAATGGCTCAGCTCGGATCCGGCCCCGTTTCCTTACTCCCGG CCGTTCGACGAGGCCCGATTCGATCCGTTGGTGACCCTGCACACCAGCGGCTCGACAGGCACCCCGAAGCCGATC ATCGTGCGCCAGGGAACTGTTGCCATCGCAGACGAATTTCGAAACCTACCTGAATATCAGGATGCTGAGTTCCTG TGGAAAGGATGGGCATCTCGTTCCAACCGAATGTTCATGCCCATGCCGCTCTTCCACACCGCTGGCCTCACAGCC TTCCTCGTGGTCCTTACTATATTTTACGGGGTGCCACTCGCGTTGGGCATACCAGACCAGCCCCTCTCCGCTGAC TTGGTGGAGAGGTGCCTACGTTGTTCTCATGCCGACTCGGCATTCCTTCCGCCCTCGATTGTGGAGGAACTGAGC TCGACGGAGAAGAGCATGGATACACTCAAGAAGCTCAACTTTGTTGGCTTCGGTGGCGGTAGGTACCATCAGACG TAGATTCCGACATTGGCTGAGGAAAACTGCGCAGGAAACCTATCCCAGGCGGCCGGTGATAGACTTGTGAAGCAG GGGGTCATGCTTTCTAATGGCATCTCGCCAACAGAGTAAGTACATTGCGAGAAGGCCGCGGACCGTCTAATTGAT GATGTGTTTCGCCAGAAACCTTCCCTATGCCATTTACTGGCAGCCTAGTCCCGAGGACTGGCAATACTTCATCTT CAATAGCGAGCTTATGGGGGCGGTTTGGCACATGAAAGACGAGAAAGAAGGCATTTACGAGCTGATCATCTCTCG AAAAGACGCGACGGATCCTCGAGATCAGCCGGTATTTTACACGTTTCCCAACGCCACCGAGTGGTCAACCGGAGA TCTTTACAGAGCCCACCCTTATCTGCCCGATCATTGGGCTTTCCACGGCCGGGCCGATGATATCATTGTCTTCTC GAATGGAGAGAAACTTAATCCAATCACAATCGAAAACACCATCATGGGGCATCCTGCTGTCAAAGGAGCCTTGGT TGTTGGGCAGGATAGGTTTCAACCCGCACTCATCGTCGAGCCAATGCATGACCCAAAAGACGACCAAGAGGCAAA GGCATTGCTTGAAGATATATGGGAGCTGATTGATGAGGCAAACCGGGTGGCGGTCAGGCATGGCCGCATCGTTCG CCAGCTAATTTCCATCTCAGATCCTGGCATCCCATTCTTTCGGGCGTCAAAGGGTACTATACAGCGAAGTCCAAC GATACGAGCCTACCAGAAGCATATTGATGGGATTTACGAGCGCGCTGAAGCAACTGACATGCAAGATGTGACGCC ACTGGACTTTACCAGCGAAGAAACACTAGGGAATTCCATCATTCGACTGATAAACGATCATGTTGGGGTGCAGAT TGTTGAAACGAGCACAGACTTGTTCTCTCTCGGCATCGACTCGCTTCAGGTCTTACGGATATCAAAGATACTTGG TGCGAGCACCGGCGCCGCTGGAGTGGCATTGGATCCCAATGTAATTGCACCTCACTTGGTTTACTCGAACCCGTC ACCGCAGTATCTCGCCTCTTACCTCTTCTCGGCATCCAAGGATGTAAGCAACGCAAAGAAGGAAGAGACTGAGCG GGAGACACAACTACTCGAGACTCTCATATCCAAGTACACCAAGGATCTCCCCGCCTCAAAGGCATACGATAAGCC CGCACCCCTTGACGATGACCAGACAATTCTTCTGACGGGCAGTACTGGCTCACTCGGTTCCTACCTTCTCGAAAG ACTTTGCACATTGGCGTGCGTCAAGAAGATACTTGTTCTCAATCGCGGTCAAGATGGCGGCAAGTCACGTCAAGG CTCTGGCAACGAGGCTCGAGGTTTGAGCACAGACTTTGCCAAGGTCGAGTTTCTCGGCACCGACCTTTCACTTCC AGATCTAGGTCTCGGTGAGGCAAAGTATGGAGAGCTTCTCGTGTCGGTGGATCGAATTATCCATAACGCATGGCC CGTCAACCTCAACATCATGAGCGTCATGCCCTTTGAACCACATATTCGCGGCGTGCGACACTTGGTCGACTTTTC AACCAAGGCCGTTAAGCGCGTCCCTATCCTCTTCATCTCCAGCATCGGCACAGCAAGCGCTTGGCAATCGACCAA ATATGTCCCCGAACGTGCCCTTGAAGACTTGTCTCTCGCCAATACGGGCTACGGCCGCTCCAAGCTGGCTGCAAG TCTCATTCTGGACTCGGCAGTGCGATACGCCGGAACCGCTGCCGCGTCGGTCCGAGTGGGACAGATTGCCGGGCC ACGAAGCCAGAAGGGCATGTGGAACAAGCAAGAGTATATACCGAGCATGATTGCCAGCTCTCTCTACCTTGGCAT GCTGCCAGACAACTTTGGTACGGGTGAGGAGGTTGACTGGATGGCCATCGAAGACGTCACCGCTCTCATTCTCGA CGTGGCCGGCATAACCACCAACACTCCCGTCTCAGCCATCGACGGCTACTTCCACAGCGTCAACCCGGCCAAGAC AACATGGGGCCAGCTCGCAGGTGAGCTCCTAGAATACTACTCCGGAAGGGTACGGCTGGTCAGCTTCGAGGAATG GGTTACTGCCATTGAAAAGAGCGCGAGCACCACTACGGATATATCGAGAAATCCTGCCATCAAGCTCCTCGACCT GTACAAGGGGATGCTGCAAGCCTCTCGCCAAGGGCTCAGTCACGTCAATTTCGAAATGTCGAGGACTATGAGCCG CAGCAGGACAGTGGCTCAGCTGGGCCCCATCACTGCCGATCTGCTGAGGAATTGGTGCTCTCAGTGGGGGTTTGA GTCCGATGCGATCAGTTTGCAGGCCTGA

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