Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophcf2|05636
Gene name
Location	scaffold_06:1379608..1383575
Strand	-
Gene length (bp)	3967
Transcript length (bp)	3750
Coding sequence length (bp)	3750
Protein length (aa)	1250

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF13236	CLU	Clustered mitochondria	2.7E-77	350	572
PF12807	eIF3_p135	Translation initiation factor eIF3 subunit 135	4.6E-53	708	869
PF13424	TPR_12	Tetratricopeptide repeat	4.3E-07	959	1010
PF13424	TPR_12	Tetratricopeptide repeat	3.8E-10	1028	1098
PF13424	TPR_12	Tetratricopeptide repeat	5.3E-10	1067	1139
PF15044	CLU_N	Mitochondrial function, CLU-N-term	8.7E-21	69	141
PF13374	TPR_10	Tetratricopeptide repeat	3.5E-05	982	1021
PF13374	TPR_10	Tetratricopeptide repeat	8.3E-03	1028	1065
PF13374	TPR_10	Tetratricopeptide repeat	1.2E-03	1068	1103

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 41	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in: Will et al., G3, 2020

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
Fungus	Fungus in pure culture	175.61	80.41	270.81
Alive	In ants, during behavior modification	127.80	61.09	194.52
Dead	In ants, recently dead	118.61	57.37	179.85

Differential expression

Label1	Label2	Q-value	Significant difference
Alive	Fungus	0.186742	no
Alive	Dead	0.747429	no
Dead	Fungus	0.085325	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophcf2|05636 MAGESAYQASAAASPKPDNAIEGENGKTTSSNTEEGQPGVEAGSDAPINLTILLPDAETEKIQLMVSSQEQVHEV RQSIIELPVAFRYTCFHLEYLGSRVNDFTPIVEISGMNSNPEFRLVRDPYTEKEARIHFVRVRELIGAAGDRADI SQGILPGLSLFESLCLNNQLRMGQLPVHDYDFQVPPSLTSLVPAPLDSAPKTVKSIALSPWNPPTCHLRQRGHLL YILVTTNEGEQFQITSHISGFFVNKSSNTKFDPHPRPGPKGHSAHSLLDLLHLLSPSFSESFMQLQEHNNQRDPL AIFQVTNALPAAPWAVPPPSSSLCLHLPDTTRPQEALLLAGVENLDTLRDWNEEFQSAKELPRETVQDRVFRERL LSKLFADYNDAATKGAVMVVRGELSPLNPTEGRDAQIFVYNNIFFSFGTDGVGTFTSEGGDEAARAATGKDVTGV MLVHQLDIDGLFTPATVVVDYLGRRIVGQSIVPGIFKQRDANENQIDYGAADGKDVVAADERFAPVFAQLSKALK VKQHPVWDKDGKRFDLKTSVETKGLIGTDGRKYVLDLYRITPFDILWLEEIDAAASEGDGRNYPHRMTVLRTELV ESFARFKMKQWVDGKLVRRAATGHKNDARPGSDSQASTLVASEIRDSLDIADFKFALNPDAFSGQHPQTDEEKAQ YEEDEKEVREACQYLRVQVIPDLLRELSHSEISFPMDGQSLSRLLHKRGINIRYLGMVATMATDQRLRCLRETCI QDMVARAFKHVAAAYLRSVPVPLTPACVSHLLNCLLGHDLNPKPCADVDESLRKLYPDADLSFELVAPEDVRAAI KRQILQRYRYTLDPAWYLNMRSIQLLREISLRLGLQIHAKDYIFGSSDKARSPAIGQEPRHSTEHINGGTKRKKK KTRDGSPSSMESTTANHTFSPDDIADLIPLVKHSSPRSALAEEALEAGRLSILQNQKKLGQELLLESLSLHEQIY GILHPEVAKVYNSLSMLYYQLDDKEAAIELARKAIVVAERTVGIDSAETLLNYLNLSLFLHQDGDSRGALTASKH ALMLWRIIYGPDHPDSITTINNAAVMLQHLKEYHDSRLWFQESLRVCEIVFGKQSVNSATLLFQLAQALALDHDS KGAVARMRESYNIFLSELGPEDKNTKEAENWLEQLTQNAVSIAKHAKDAQTKRIRSGIRFAAATVPSQLSASRPS QHMNPTSQIDSRSIDELIKFIEGGEQKSKSAKKRPSRGNPKRRGQSVTA*
Coding	>Ophcf2|05636 ATGGCCGGCGAATCAGCTTATCAAGCCTCTGCTGCGGCCTCTCCTAAGCCAGACAATGCCATCGAGGGGGAAAAT GGTAAAACCACCTCGTCGAATACAGAAGAAGGCCAGCCGGGCGTAGAAGCAGGATCCGATGCTCCGATAAACTTG ACTATTCTCCTTCCTGATGCGGAGACTGAAAAGATTCAGTTGATGGTTTCCTCGCAAGAACAAGTCCATGAAGTC CGTCAATCCATCATCGAGTTGCCTGTAGCTTTTCGCTACACCTGCTTTCATCTCGAATACCTTGGAAGTAGAGTC AATGACTTCACCCCGATTGTCGAGATATCAGGCATGAACTCGAATCCCGAGTTTCGCTTGGTTCGAGACCCGTAC ACCGAAAAGGAGGCGAGGATTCATTTTGTCAGAGTTCGAGAGCTGATAGGTGCGGCCGGAGATCGAGCCGACATA TCACAAGGCATCCTTCCGGGTCTTTCGCTCTTCGAAAGTCTTTGCTTAAACAATCAGCTTCGCATGGGCCAACTA CCCGTCCACGATTATGACTTCCAGGTGCCACCGTCGCTCACTAGCCTAGTTCCAGCCCCCCTAGATTCTGCACCG AAGACAGTCAAATCGATAGCACTATCGCCCTGGAATCCTCCGACATGCCATCTCAGGCAGCGGGGCCATCTTCTT TACATACTCGTGACAACTAACGAGGGCGAGCAGTTCCAAATCACCTCCCACATCTCTGGCTTTTTTGTCAACAAA TCATCAAATACCAAGTTTGATCCCCATCCGCGGCCCGGGCCCAAAGGACACTCGGCACACTCTCTGCTCGACCTC CTTCACCTCCTGTCACCTTCCTTCTCGGAGAGTTTCATGCAACTTCAGGAACACAATAATCAGAGAGATCCCCTC GCCATTTTCCAGGTTACCAACGCTCTACCAGCCGCTCCTTGGGCTGTGCCGCCACCGAGTTCTTCTCTCTGCCTT CACCTCCCCGACACAACAAGACCTCAGGAGGCTCTTCTTTTAGCTGGTGTCGAGAATTTGGACACCTTGCGTGAT TGGAACGAGGAGTTTCAATCGGCCAAGGAACTACCCAGAGAAACTGTGCAAGATCGGGTATTCCGTGAGCGTCTG CTGTCCAAACTATTCGCCGATTACAACGATGCTGCGACAAAAGGTGCAGTCATGGTGGTCCGCGGAGAGCTTTCT CCGCTGAACCCAACCGAGGGTAGAGACGCCCAGATTTTCGTGTACAACAACATTTTCTTCTCCTTCGGCACTGAT GGGGTAGGTACTTTCACATCCGAGGGCGGCGACGAGGCTGCACGAGCTGCGACAGGAAAAGACGTCACTGGCGTG ATGCTGGTCCATCAGCTCGATATCGATGGCCTCTTTACCCCTGCGACAGTGGTAGTAGACTATCTCGGGCGACGC ATTGTGGGCCAAAGCATAGTTCCTGGTATCTTCAAGCAGCGTGATGCAAACGAGAACCAGATAGACTACGGAGCG GCGGACGGTAAGGACGTGGTTGCAGCAGACGAGCGATTTGCTCCCGTATTTGCGCAGCTCTCCAAAGCCCTGAAG GTCAAGCAACATCCAGTCTGGGATAAGGACGGAAAGAGATTCGATCTGAAGACTAGTGTTGAAACCAAGGGTTTG ATAGGCACGGACGGACGGAAGTACGTCCTTGACCTCTACAGAATCACGCCTTTTGACATACTCTGGCTCGAAGAA ATAGATGCCGCCGCAAGCGAAGGTGACGGCAGAAACTATCCTCATCGGATGACAGTGCTACGGACGGAGCTCGTG GAGTCCTTTGCGCGGTTCAAGATGAAGCAATGGGTAGACGGAAAGCTGGTGCGTCGGGCAGCTACAGGCCACAAG AACGACGCACGCCCAGGTAGCGACAGCCAGGCCTCCACCCTTGTTGCGTCTGAGATCAGGGATTCACTCGATATA GCCGACTTCAAGTTTGCCCTCAATCCCGACGCATTCAGCGGTCAGCATCCTCAGACAGATGAAGAGAAGGCTCAG TACGAAGAGGACGAGAAGGAGGTCCGCGAAGCCTGCCAATATCTACGTGTTCAGGTCATCCCGGATCTGCTTCGC GAGCTCTCTCATTCCGAAATCAGCTTTCCCATGGATGGTCAATCTCTCAGCCGCCTCTTACACAAACGTGGCATC AATATTAGGTATCTTGGCATGGTAGCTACAATGGCCACGGATCAACGTCTTAGGTGTCTGCGGGAGACATGCATT CAGGACATGGTGGCGCGTGCGTTCAAGCATGTTGCTGCGGCCTATCTTCGCTCTGTCCCTGTTCCTCTCACGCCG GCTTGCGTGTCTCACCTGCTGAATTGTCTTCTTGGTCATGATCTTAATCCCAAGCCATGCGCTGACGTCGATGAA TCTTTGCGCAAACTGTACCCCGACGCCGACTTGTCATTTGAGCTTGTCGCCCCCGAGGACGTCAGGGCGGCTATC AAGCGGCAAATTCTCCAACGATACAGATACACACTGGATCCCGCATGGTATTTGAATATGCGTAGTATACAGCTG CTGCGCGAAATTAGCTTGAGACTCGGCCTTCAGATACATGCGAAAGACTATATTTTCGGGAGCTCAGATAAGGCA AGAAGTCCTGCGATCGGGCAAGAACCACGCCATTCAACTGAGCACATCAACGGAGGGACAAAGAGAAAGAAGAAG AAGACGCGTGACGGTTCCCCATCGTCAATGGAGTCGACGACGGCCAATCACACCTTCAGCCCTGATGATATTGCT GACTTAATTCCGCTTGTGAAGCATTCGAGCCCTCGAAGCGCGCTCGCAGAGGAAGCACTCGAGGCTGGTCGGCTC TCGATCCTCCAGAATCAGAAGAAGCTGGGTCAGGAACTTTTGCTGGAATCTTTATCGCTACACGAGCAAATCTAC GGGATCTTGCACCCCGAGGTGGCCAAGGTCTACAATAGTCTTTCGATGTTGTATTACCAGTTGGATGATAAAGAA GCGGCCATCGAGCTGGCAAGAAAAGCGATTGTTGTCGCCGAACGCACTGTCGGGATCGACTCGGCCGAGACATTA CTGAACTACTTGAACCTTAGCCTGTTTCTCCATCAAGATGGTGACAGCAGAGGTGCCCTCACCGCGTCCAAGCAC GCATTAATGCTGTGGAGGATCATTTATGGGCCTGATCATCCTGATTCCATCACTACCATCAACAACGCTGCGGTG ATGTTGCAGCACCTAAAGGAATACCACGACTCGAGGCTGTGGTTTCAGGAATCGCTCCGTGTGTGCGAAATCGTC TTCGGAAAACAGTCTGTCAACTCGGCCACTCTGCTTTTTCAACTAGCCCAGGCTCTGGCGCTGGATCACGATTCG AAAGGGGCAGTCGCCCGCATGCGCGAATCCTACAATATCTTCCTTAGCGAGCTTGGACCCGAAGACAAGAACACC AAAGAGGCCGAAAACTGGCTCGAGCAACTAACTCAGAACGCCGTTTCCATAGCGAAGCATGCCAAGGACGCACAG ACAAAGCGCATTCGATCAGGCATCCGTTTCGCAGCAGCAACAGTCCCGTCGCAACTGTCGGCCTCCAGACCTTCC CAACACATGAACCCAACCTCACAAATTGATTCTCGCAGCATTGACGAGCTCATCAAGTTCATCGAGGGCGGAGAA CAAAAGTCCAAGTCGGCCAAGAAAAGGCCCAGCCGCGGCAACCCCAAGAGGCGAGGGCAGAGCGTCACGGCATAA
Transcript	>Ophcf2|05636 ATGGCCGGCGAATCAGCTTATCAAGCCTCTGCTGCGGCCTCTCCTAAGCCAGACAATGCCATCGAGGGGGAAAAT GGTAAAACCACCTCGTCGAATACAGAAGAAGGCCAGCCGGGCGTAGAAGCAGGATCCGATGCTCCGATAAACTTG ACTATTCTCCTTCCTGATGCGGAGACTGAAAAGATTCAGTTGATGGTTTCCTCGCAAGAACAAGTCCATGAAGTC CGTCAATCCATCATCGAGTTGCCTGTAGCTTTTCGCTACACCTGCTTTCATCTCGAATACCTTGGAAGTAGAGTC AATGACTTCACCCCGATTGTCGAGATATCAGGCATGAACTCGAATCCCGAGTTTCGCTTGGTTCGAGACCCGTAC ACCGAAAAGGAGGCGAGGATTCATTTTGTCAGAGTTCGAGAGCTGATAGGTGCGGCCGGAGATCGAGCCGACATA TCACAAGGCATCCTTCCGGGTCTTTCGCTCTTCGAAAGTCTTTGCTTAAACAATCAGCTTCGCATGGGCCAACTA CCCGTCCACGATTATGACTTCCAGGTGCCACCGTCGCTCACTAGCCTAGTTCCAGCCCCCCTAGATTCTGCACCG AAGACAGTCAAATCGATAGCACTATCGCCCTGGAATCCTCCGACATGCCATCTCAGGCAGCGGGGCCATCTTCTT TACATACTCGTGACAACTAACGAGGGCGAGCAGTTCCAAATCACCTCCCACATCTCTGGCTTTTTTGTCAACAAA TCATCAAATACCAAGTTTGATCCCCATCCGCGGCCCGGGCCCAAAGGACACTCGGCACACTCTCTGCTCGACCTC CTTCACCTCCTGTCACCTTCCTTCTCGGAGAGTTTCATGCAACTTCAGGAACACAATAATCAGAGAGATCCCCTC GCCATTTTCCAGGTTACCAACGCTCTACCAGCCGCTCCTTGGGCTGTGCCGCCACCGAGTTCTTCTCTCTGCCTT CACCTCCCCGACACAACAAGACCTCAGGAGGCTCTTCTTTTAGCTGGTGTCGAGAATTTGGACACCTTGCGTGAT TGGAACGAGGAGTTTCAATCGGCCAAGGAACTACCCAGAGAAACTGTGCAAGATCGGGTATTCCGTGAGCGTCTG CTGTCCAAACTATTCGCCGATTACAACGATGCTGCGACAAAAGGTGCAGTCATGGTGGTCCGCGGAGAGCTTTCT CCGCTGAACCCAACCGAGGGTAGAGACGCCCAGATTTTCGTGTACAACAACATTTTCTTCTCCTTCGGCACTGAT GGGGTAGGTACTTTCACATCCGAGGGCGGCGACGAGGCTGCACGAGCTGCGACAGGAAAAGACGTCACTGGCGTG ATGCTGGTCCATCAGCTCGATATCGATGGCCTCTTTACCCCTGCGACAGTGGTAGTAGACTATCTCGGGCGACGC ATTGTGGGCCAAAGCATAGTTCCTGGTATCTTCAAGCAGCGTGATGCAAACGAGAACCAGATAGACTACGGAGCG GCGGACGGTAAGGACGTGGTTGCAGCAGACGAGCGATTTGCTCCCGTATTTGCGCAGCTCTCCAAAGCCCTGAAG GTCAAGCAACATCCAGTCTGGGATAAGGACGGAAAGAGATTCGATCTGAAGACTAGTGTTGAAACCAAGGGTTTG ATAGGCACGGACGGACGGAAGTACGTCCTTGACCTCTACAGAATCACGCCTTTTGACATACTCTGGCTCGAAGAA ATAGATGCCGCCGCAAGCGAAGGTGACGGCAGAAACTATCCTCATCGGATGACAGTGCTACGGACGGAGCTCGTG GAGTCCTTTGCGCGGTTCAAGATGAAGCAATGGGTAGACGGAAAGCTGGTGCGTCGGGCAGCTACAGGCCACAAG AACGACGCACGCCCAGGTAGCGACAGCCAGGCCTCCACCCTTGTTGCGTCTGAGATCAGGGATTCACTCGATATA GCCGACTTCAAGTTTGCCCTCAATCCCGACGCATTCAGCGGTCAGCATCCTCAGACAGATGAAGAGAAGGCTCAG TACGAAGAGGACGAGAAGGAGGTCCGCGAAGCCTGCCAATATCTACGTGTTCAGGTCATCCCGGATCTGCTTCGC GAGCTCTCTCATTCCGAAATCAGCTTTCCCATGGATGGTCAATCTCTCAGCCGCCTCTTACACAAACGTGGCATC AATATTAGGTATCTTGGCATGGTAGCTACAATGGCCACGGATCAACGTCTTAGGTGTCTGCGGGAGACATGCATT CAGGACATGGTGGCGCGTGCGTTCAAGCATGTTGCTGCGGCCTATCTTCGCTCTGTCCCTGTTCCTCTCACGCCG GCTTGCGTGTCTCACCTGCTGAATTGTCTTCTTGGTCATGATCTTAATCCCAAGCCATGCGCTGACGTCGATGAA TCTTTGCGCAAACTGTACCCCGACGCCGACTTGTCATTTGAGCTTGTCGCCCCCGAGGACGTCAGGGCGGCTATC AAGCGGCAAATTCTCCAACGATACAGATACACACTGGATCCCGCATGGTATTTGAATATGCGTAGTATACAGCTG CTGCGCGAAATTAGCTTGAGACTCGGCCTTCAGATACATGCGAAAGACTATATTTTCGGGAGCTCAGATAAGGCA AGAAGTCCTGCGATCGGGCAAGAACCACGCCATTCAACTGAGCACATCAACGGAGGGACAAAGAGAAAGAAGAAG AAGACGCGTGACGGTTCCCCATCGTCAATGGAGTCGACGACGGCCAATCACACCTTCAGCCCTGATGATATTGCT GACTTAATTCCGCTTGTGAAGCATTCGAGCCCTCGAAGCGCGCTCGCAGAGGAAGCACTCGAGGCTGGTCGGCTC TCGATCCTCCAGAATCAGAAGAAGCTGGGTCAGGAACTTTTGCTGGAATCTTTATCGCTACACGAGCAAATCTAC GGGATCTTGCACCCCGAGGTGGCCAAGGTCTACAATAGTCTTTCGATGTTGTATTACCAGTTGGATGATAAAGAA GCGGCCATCGAGCTGGCAAGAAAAGCGATTGTTGTCGCCGAACGCACTGTCGGGATCGACTCGGCCGAGACATTA CTGAACTACTTGAACCTTAGCCTGTTTCTCCATCAAGATGGTGACAGCAGAGGTGCCCTCACCGCGTCCAAGCAC GCATTAATGCTGTGGAGGATCATTTATGGGCCTGATCATCCTGATTCCATCACTACCATCAACAACGCTGCGGTG ATGTTGCAGCACCTAAAGGAATACCACGACTCGAGGCTGTGGTTTCAGGAATCGCTCCGTGTGTGCGAAATCGTC TTCGGAAAACAGTCTGTCAACTCGGCCACTCTGCTTTTTCAACTAGCCCAGGCTCTGGCGCTGGATCACGATTCG AAAGGGGCAGTCGCCCGCATGCGCGAATCCTACAATATCTTCCTTAGCGAGCTTGGACCCGAAGACAAGAACACC AAAGAGGCCGAAAACTGGCTCGAGCAACTAACTCAGAACGCCGTTTCCATAGCGAAGCATGCCAAGGACGCACAG ACAAAGCGCATTCGATCAGGCATCCGTTTCGCAGCAGCAACAGTCCCGTCGCAACTGTCGGCCTCCAGACCTTCC CAACACATGAACCCAACCTCACAAATTGATTCTCGCAGCATTGACGAGCTCATCAAGTTCATCGAGGGCGGAGAA CAAAAGTCCAAGTCGGCCAAGAAAAGGCCCAGCCGCGGCAACCCCAAGAGGCGAGGGCAGAGCGTCACGGCATAA
Gene	>Ophcf2|05636 ATGGCCGGCGAATCAGCTTATCAAGCCTCTGCTGCGGCCTCTCCTAAGCCAGGTAAAATCTCACTCTCTCCGCCA AGAGTCGGAACATCGAGAGATCAAGGTTCTTCTGGGTCTGAATCTGTGGCTAAACTACATTGCGTGTTGCACCTA GACAATGCCATCGAGGGGGAAAATGGTAAAACCACCTCGTCGAATACAGAAGAAGGCCAGCCGGGCGTAGAAGCA GGATCCGATGGTGAGCTGATTTCGCTCGTGTATGCAATCCCCCAGGTCTTTGCCATTGTCTTACTGCGCATCTAG CTCCGATAAACTTGACTATTCTCCTTCCTGATGCGGAGACTGAAAAGATTCAGTTGATGGTTAGACAATCAACAT TTCGACCTTCAGGACATATACTCATTCGGCAAGTTAGGTTTCCTCGCAAGAACAAGTCCATGAAGTCCGTCAATC CATCATCGAGTTGCCTGTAGCTTTTCGCTACACCTGCTTTCATCTCGAATACCTTGGAAGTAGAGTCAATGACTT CACCCCGATTGTCGAGATATCAGGCATGAACTCGAATCCCGAGTTTCGCTTGGTTCGAGACCCGTACACCGAAAA GGAGGCGAGGATTCATTTTGTCAGAGTTCGAGAGCTGATAGGTGCGGCCGGAGATCGAGCCGACATATCACAAGG CATCCTTCCGGGTCTTTCGCTCTTCGAAAGTCTTTGCTTAAACAATCAGCTTCGCATGGGCCAACTACCCGTCCA CGATTATGACTTCCAGGTGCCACCGTCGCTCACTAGCCTAGTTCCAGCCCCCCTAGATTCTGCACCGAAGACAGT CAAATCGATAGCACTATCGCCCTGGAATCCTCCGACATGCCATCTCAGGCAGCGGGGCCATCTTCTTTACATACT CGTGACAACTAACGAGGGCGAGCAGTTCCAAATCACCTCCCACATCTCTGGCTTTTTTGTCAACAAATCATCAAA TACCAAGTTTGATCCCCATCCGCGGCCCGGGCCCAAAGGACACTCGGCACACTCTCTGCTCGACCTCCTTCACCT CCTGTCACCTTCCTTCTCGGAGAGTTTCATGCAACTTCAGGAACACAATAATCAGAGAGATCCCCTCGCCATTTT CCAGGTTACCAACGCTCTACCAGCCGCTCCTTGGGCTGTGCCGCCACCGAGTTCTTCTCTCTGCCTTCACCTCCC CGACACAACAAGACCTCAGGAGGCTCTTCTTTTAGCTGGTGTCGAGAATTTGGACACCTTGCGTGATTGGAACGA GGAGTTTCAATCGGCCAAGGAACTACCCAGAGAAACTGTGCAAGATCGGGTATTCCGTGAGCGTCTGCTGTCCAA ACTATTCGCCGATTACAACGATGCTGCGACAAAAGGTGCAGTCATGGTGGTCCGCGGAGAGCTTTCTCCGCTGAA CCCAACCGAGGGTAGAGACGCCCAGATTTTCGTGTACAACAACATTTTCTTCTCCTTCGGCACTGATGGGGTAGG TACTTTCACATCCGAGGGCGGCGACGAGGCTGCACGAGCTGCGACAGGAAAAGACGTCACTGGCGTGATGCTGGT CCATCAGCTCGATATCGATGGCCTCTTTACCCCTGCGACAGTGGTAGTAGACTATCTCGGGCGACGCATTGTGGG CCAAAGCATAGTTCCTGGTATCTTCAAGCAGCGTGATGCAAACGAGAACCAGATAGACTACGGAGCGGCGGACGG TAAGGACGTGGTTGCAGCAGACGAGCGATTTGCTCCCGTATTTGCGCAGCTCTCCAAAGCCCTGAAGGTCAAGCA ACATCCAGTCTGGGATAAGGACGGAAAGAGATTCGATCTGAAGACTAGTGTTGAAACCAAGGGTTTGATAGGCAC GGACGGACGGAAGTACGTCCTTGACCTCTACAGAATCACGCCTTTTGACATACTCTGGCTCGAAGAAATAGATGC CGCCGCAAGCGAAGGTGACGGCAGAAACTATCCTCATCGGATGACAGTGCTACGGACGGAGCTCGTGGAGTCCTT TGCGCGGTTCAAGATGAAGCAATGGGTAGACGGAAAGCTGGTGCGTCGGGCAGCTACAGGCCACAAGAACGACGC ACGCCCAGGTAGCGACAGCCAGGCCTCCACCCTTGTTGCGTCTGAGATCAGGGATTCACTCGATATAGCCGACTT CAAGTTTGCCCTCAATCCCGACGCATTCAGCGGTCAGCATCCTCAGACAGATGAAGAGAAGGCTCAGTACGAAGA GGACGAGAAGGAGGTCCGCGAAGCCTGCCAATATCTACGTGTTCAGGTCATCCCGGATCTGCTTCGCGAGCTCTC TCATTCCGAAATCAGCTTTCCCATGGATGGTCAATCTCTCAGCCGCCTCTTACACAAACGTGGCATCAATATTAG GTATCTTGGCATGGTAGCTACAATGGCCACGGATCAACGTCTTAGGTGTCTGCGGGAGACATGCATTCAGGACAT GGTGGCGCGTGCGTTCAAGCATGTTGCTGCGGCCTATCTTCGCTCTGTCCCTGTTCCTCTCACGCCGGCTTGCGT GTCTCACCTGCTGAATTGTCTTCTTGGTCATGATCTTAATCCCAAGCCATGCGCTGACGTCGATGAATCTTTGCG CAAACTGTACCCCGACGCCGACTTGTCATTTGAGCTTGTCGCCCCCGAGGACGTCAGGGCGGCTATCAAGCGGCA AATTCTCCAACGATACAGATACACACTGGATCCCGCATGGTATTTGAATATGCGTAGTATACAGCTGCTGCGCGA AATTAGCTTGAGACTCGGCCTTCAGATACATGCGAAAGACTATATTTTCGGGAGCTCAGATAAGGCAAGAAGTCC TGCGATCGGGCAAGAACCACGCCATTCAACTGAGCACATCAACGGAGGGACAAAGAGAAAGAAGAAGAAGACGCG TGACGGTTCCCCATCGTCAATGGAGTCGACGACGGCCAATCACACCTTCAGCCCTGATGATATTGCTGACTTAAT TCCGCTTGTGAAGCATTCGAGCCCTCGAAGCGCGCTCGCAGAGGAAGCACTCGAGGCTGGTCGGCTCTCGATCCT CCAGAATCAGAAGAAGCTGGGTCAGGAACTTTTGCTGGAATCTTTATCGCTACACGAGCAAATCTACGGGATCTT GCACCCCGAGGTGGCCAAGGTCTACAATAGTCTTTCGATGTTGTATTACCAGTTGGATGATAAAGAAGCGGCCAT CGAGCTGGCAAGAAAAGCGATTGTTGTCGCCGAACGCACTGTCGGGATCGACTCGGCCGAGACATTACTGAACTA CTTGAACCTTAGCCTGTTTCTCCATCAAGATGGTGACAGCAGAGGTGCCCTCACCGCGTCCAAGCACGCATTAAT GCTGTGGAGGATCATTTATGGGCCTGATCATCCTGATTCCATCACTACCATCAACAACGCTGCGGTGATGTTGCA GCACCTAAAGGAATACCACGACTCGAGGCTGTGGTTTCAGGAATCGCTCCGTGTGTGCGAAATCGTCTTCGGAAA ACAGTCTGTCAACTCGGCCACTCTGCTTTTTCAACTAGCCCAGGCTCTGGCGCTGGATCACGATTCGAAAGGGGC AGTCGCCCGCATGCGCGAATCCTACAATATCTTCCTTAGCGAGCTTGGACCCGAAGACAAGAACACCAAAGAGGC CGAAAACTGGCTCGAGCAACTAACTCAGAACGCCGTTTCCATAGCGAAGCATGCCAAGGACGCACAGACAAAGCG CATTCGATCAGGCATCCGTTTCGCAGCAGCAACAGTCCCGTCGCAACTGTCGGCCTCCAGACCTTCCCAACACAT GAACCCAACCTCACAAATTGATTCTCGCAGCATTGACGAGCTCATCAAGTTCATCGAGGGCGGAGAACAAAAGTC CAAGTCGGCCAAGAAAAGGCCCAGCCGCGGCAACCCCAAGAGGCGAGGGCAGAGCGTCACGGCATAA