Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophcf2|04805
Gene name
Location	scaffold_05:1632014..1636253
Strand	+
Gene length (bp)	4239
Transcript length (bp)	2643
Coding sequence length (bp)	2643
Protein length (aa)	881

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00067	p450	Cytochrome P450	8.1E-27	600	864
PF01494	FAD_binding_3	FAD binding domain	1.1E-22	10	369

GO

GO Term	Description	Terminal node
GO:0004497	monooxygenase activity	Yes
GO:0071949	FAD binding	Yes
GO:0020037	heme binding	Yes
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Yes
GO:0005506	iron ion binding	Yes
GO:0003824	catalytic activity	No
GO:0097159	organic cyclic compound binding	No
GO:0043168	anion binding	No
GO:0046906	tetrapyrrole binding	No
GO:1901363	heterocyclic compound binding	No
GO:0043169	cation binding	No
GO:0005488	binding	No
GO:0016491	oxidoreductase activity	No
GO:1901265	nucleoside phosphate binding	No
GO:0043167	ion binding	No
GO:0046914	transition metal ion binding	No
GO:0046872	metal ion binding	No
GO:0003674	molecular_function	No
GO:0050660	flavin adenine dinucleotide binding	No
GO:0000166	nucleotide binding	No
GO:0036094	small molecule binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 26	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in: Will et al., G3, 2020

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
Fungus	Fungus in pure culture	0.12	0.00	0.28
Alive	In ants, during behavior modification	1760.14	229.73	3290.54
Dead	In ants, recently dead	1300.44	390.07	2210.81

Differential expression

Label1	Label2	Q-value	Significant difference
Alive	Fungus	0.000238	yes
Alive	Dead	0.328610	no
Dead	Fungus	0.000238	yes

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophcf2|04805 MASLSAKDDFKVLIIGGSIAGLTLAHCLEKLKVSYEILEQGHDISPQVGASVGILPNGAQVLDQLGIFDEVEEAI EPLTFARIRYPDGFFFHSRYPSVLRSRFGYPLAFLERRRFLEILYGKLEGKHDVHTGQRVVRIDDEGHRAVVRTA DGKEYTGDLVVGADGLHSIVRSEIWRHEAEAGTGVVTTKEKESLRIDYACVFGISSGVKGVPAGLQLSLLDHGLT IHVFNGKDTKAFWFVIIKTDRRYGYGQRPQYTNDDARKTCAAISSKVIDHGLTFGHLWDRCQVFTMTPLEEGNFS TWHRGRLVCVGDAVRKVTPNIGQGANMAIEDVAVLANAIWRRCRKTKPASITAAVSEIRLARTRSVCRQSEMLTR MQAHEGLLRRVLVNVPVVGPCAGLTKWVAAVRNVWAARDSIHKGYSKASRLCPSYGKSAFQIPTMTRMDVFLCDR TMTREYYSLDEEHMSFQAAMSEEFQFKYSLPGQQHDIRKIPNSVIGKALSWQRNRSNNPQDPFFADFSKEFLHGF QHEMEAFRRKQPSSSLAFFSHAAEPKAEGWMAVPCFPLALKIVARLTTKSLFGEPLCRDDYFLDLCCRFADAVPR VAMVLRCFPSFARPFVAKYLPGTRLVQKLRVFVLDEVTSRRKSRHENPIKDLLDFVMNWADEQPEDWSDLEVSDM IINVLVTHTIFELATRPEYVPELRDEIQECFQLHGQGTKAAVDAMHKVDSFIKETQRCNVLDAAALARLVLKPYT FSNGLHIPQGTYIFTPNSPLLQDERFYSDPNRFDGLRFARMRNDVKQRASCPLTATSEHSMHFGIGRNACPGRFM VADEVKLVMIHLLLNMELAMEGFGPRPRNVAFGKFMLPDMRARIWLKRASFARIE*
Coding	>Ophcf2|04805 ATGGCCTCCCTCTCGGCAAAAGACGACTTCAAGGTCCTCATCATCGGTGGTTCCATCGCCGGCCTCACCCTCGCC CATTGTCTCGAGAAGCTCAAGGTTTCGTACGAGATACTCGAGCAGGGCCACGACATAAGCCCCCAGGTCGGGGCA TCAGTCGGTATCCTCCCCAACGGGGCCCAGGTGTTGGACCAGCTGGGCATCTTCGACGAGGTCGAGGAGGCTATC GAGCCTCTGACGTTTGCCCGTATCCGTTACCCGGATGGCTTCTTCTTCCACAGCCGGTATCCTTCGGTGCTACGG TCTCGGTTCGGATACCCGCTTGCTTTTCTCGAACGGCGGCGTTTCCTCGAGATACTGTACGGGAAGCTCGAGGGC AAACATGACGTTCATACGGGGCAGCGGGTGGTGAGGATTGATGACGAGGGCCATCGGGCTGTTGTTCGTACGGCC GACGGAAAGGAGTATACGGGTGATTTGGTGGTTGGCGCCGATGGGTTGCACAGCATCGTGAGGTCTGAGATCTGG AGGCATGAGGCCGAGGCTGGGACGGGAGTCGTGACCACCAAGGAGAAAGAGAGCTTGAGAATCGACTACGCCTGC GTCTTTGGCATCTCATCCGGCGTCAAGGGCGTCCCAGCCGGTCTGCAACTCTCACTCCTAGATCACGGCTTAACA ATCCACGTCTTCAACGGCAAAGACACAAAGGCCTTTTGGTTCGTCATCATCAAGACGGACCGACGGTACGGCTAC GGTCAACGCCCGCAGTACACCAATGACGACGCCCGCAAGACATGCGCAGCCATATCCTCAAAGGTCATCGACCAT GGCCTCACCTTCGGTCACCTCTGGGATAGATGCCAGGTCTTCACCATGACGCCCCTGGAAGAAGGCAACTTCTCG ACCTGGCACCGCGGACGCCTCGTCTGCGTAGGCGACGCCGTCCGCAAGGTGACGCCCAACATAGGCCAAGGCGCC AACATGGCGATAGAAGACGTAGCCGTACTCGCAAACGCAATCTGGCGCCGATGCCGAAAGACGAAGCCGGCCTCC ATCACGGCCGCCGTCTCGGAGATCCGCCTGGCTCGCACCCGCAGCGTGTGCCGGCAGTCGGAGATGCTGACGCGG ATGCAGGCTCACGAGGGTCTTCTGAGGCGGGTGCTCGTCAATGTACCCGTCGTCGGTCCCTGCGCCGGCCTCACC AAATGGGTAGCTGCTGTTCGTAACGTCTGGGCCGCTCGTGATTCCATTCACAAGGGTTATTCCAAGGCAAGTCGG CTTTGTCCGAGTTATGGCAAGTCGGCGTTCCAGATTCCCACCATGACCCGTATGGACGTCTTTCTCTGTGACCGG ACCATGACGAGGGAGTATTACTCTCTCGACGAAGAGCACATGTCTTTCCAGGCTGCCATGTCCGAGGAATTCCAG TTCAAGTACTCCCTGCCAGGCCAGCAACACGACATCCGCAAGATCCCAAACTCGGTAATCGGCAAGGCCCTAAGC TGGCAAAGAAACCGATCCAACAATCCCCAAGACCCCTTCTTCGCCGACTTCTCCAAAGAGTTCCTCCACGGCTTC CAGCACGAGATGGAAGCCTTCCGTCGGAAGCAGCCGTCTTCCAGCCTGGCCTTCTTCTCGCACGCGGCCGAGCCC AAGGCCGAAGGGTGGATGGCGGTGCCTTGCTTCCCGCTGGCTTTGAAGATTGTGGCTCGGCTGACGACCAAGTCT CTCTTCGGGGAGCCGCTTTGTCGCGATGATTACTTTCTTGACTTGTGTTGTCGGTTTGCGGATGCGGTGCCGAGG GTTGCCATGGTTTTGCGCTGCTTTCCTTCTTTCGCGAGGCCCTTCGTGGCCAAGTATCTTCCCGGAACGCGGCTC GTGCAGAAGCTGCGTGTCTTCGTCCTCGACGAGGTGACGTCCAGGAGAAAGTCTCGCCATGAGAATCCCATCAAG GATCTCCTCGACTTTGTCATGAACTGGGCCGATGAGCAACCGGAAGATTGGAGCGACTTGGAGGTGTCGGACATG ATCATCAACGTCTTGGTCACTCATACCATCTTCGAGCTCGCCACGCGCCCCGAATACGTGCCTGAGCTTCGCGAC GAGATACAGGAGTGTTTTCAGCTTCACGGCCAAGGCACAAAGGCGGCCGTCGACGCCATGCACAAGGTCGATAGC TTCATCAAGGAGACGCAGAGATGCAACGTTCTCGACGCCGCTGCCCTCGCAAGACTGGTGCTCAAGCCCTACACC TTCTCCAACGGACTACACATCCCACAAGGCACATACATCTTCACCCCCAACTCGCCCCTCCTCCAAGACGAGCGC TTCTACTCGGATCCAAACCGCTTCGACGGCCTCCGCTTCGCCCGAATGCGCAACGACGTCAAGCAGCGAGCCTCG TGTCCGCTGACGGCCACCAGCGAACACAGCATGCACTTTGGCATCGGCCGCAATGCCTGTCCCGGCCGCTTCATG GTCGCGGATGAGGTCAAGCTGGTCATGATTCACCTGCTGCTCAACATGGAGCTTGCTATGGAGGGGTTTGGGCCG AGGCCGAGGAACGTGGCGTTTGGCAAGTTTATGTTGCCGGATATGAGGGCTAGGATTTGGTTGAAGAGGGCGAGT TTTGCGCGGATTGAGTAG
Transcript	>Ophcf2|04805 ATGGCCTCCCTCTCGGCAAAAGACGACTTCAAGGTCCTCATCATCGGTGGTTCCATCGCCGGCCTCACCCTCGCC CATTGTCTCGAGAAGCTCAAGGTTTCGTACGAGATACTCGAGCAGGGCCACGACATAAGCCCCCAGGTCGGGGCA TCAGTCGGTATCCTCCCCAACGGGGCCCAGGTGTTGGACCAGCTGGGCATCTTCGACGAGGTCGAGGAGGCTATC GAGCCTCTGACGTTTGCCCGTATCCGTTACCCGGATGGCTTCTTCTTCCACAGCCGGTATCCTTCGGTGCTACGG TCTCGGTTCGGATACCCGCTTGCTTTTCTCGAACGGCGGCGTTTCCTCGAGATACTGTACGGGAAGCTCGAGGGC AAACATGACGTTCATACGGGGCAGCGGGTGGTGAGGATTGATGACGAGGGCCATCGGGCTGTTGTTCGTACGGCC GACGGAAAGGAGTATACGGGTGATTTGGTGGTTGGCGCCGATGGGTTGCACAGCATCGTGAGGTCTGAGATCTGG AGGCATGAGGCCGAGGCTGGGACGGGAGTCGTGACCACCAAGGAGAAAGAGAGCTTGAGAATCGACTACGCCTGC GTCTTTGGCATCTCATCCGGCGTCAAGGGCGTCCCAGCCGGTCTGCAACTCTCACTCCTAGATCACGGCTTAACA ATCCACGTCTTCAACGGCAAAGACACAAAGGCCTTTTGGTTCGTCATCATCAAGACGGACCGACGGTACGGCTAC GGTCAACGCCCGCAGTACACCAATGACGACGCCCGCAAGACATGCGCAGCCATATCCTCAAAGGTCATCGACCAT GGCCTCACCTTCGGTCACCTCTGGGATAGATGCCAGGTCTTCACCATGACGCCCCTGGAAGAAGGCAACTTCTCG ACCTGGCACCGCGGACGCCTCGTCTGCGTAGGCGACGCCGTCCGCAAGGTGACGCCCAACATAGGCCAAGGCGCC AACATGGCGATAGAAGACGTAGCCGTACTCGCAAACGCAATCTGGCGCCGATGCCGAAAGACGAAGCCGGCCTCC ATCACGGCCGCCGTCTCGGAGATCCGCCTGGCTCGCACCCGCAGCGTGTGCCGGCAGTCGGAGATGCTGACGCGG ATGCAGGCTCACGAGGGTCTTCTGAGGCGGGTGCTCGTCAATGTACCCGTCGTCGGTCCCTGCGCCGGCCTCACC AAATGGGTAGCTGCTGTTCGTAACGTCTGGGCCGCTCGTGATTCCATTCACAAGGGTTATTCCAAGGCAAGTCGG CTTTGTCCGAGTTATGGCAAGTCGGCGTTCCAGATTCCCACCATGACCCGTATGGACGTCTTTCTCTGTGACCGG ACCATGACGAGGGAGTATTACTCTCTCGACGAAGAGCACATGTCTTTCCAGGCTGCCATGTCCGAGGAATTCCAG TTCAAGTACTCCCTGCCAGGCCAGCAACACGACATCCGCAAGATCCCAAACTCGGTAATCGGCAAGGCCCTAAGC TGGCAAAGAAACCGATCCAACAATCCCCAAGACCCCTTCTTCGCCGACTTCTCCAAAGAGTTCCTCCACGGCTTC CAGCACGAGATGGAAGCCTTCCGTCGGAAGCAGCCGTCTTCCAGCCTGGCCTTCTTCTCGCACGCGGCCGAGCCC AAGGCCGAAGGGTGGATGGCGGTGCCTTGCTTCCCGCTGGCTTTGAAGATTGTGGCTCGGCTGACGACCAAGTCT CTCTTCGGGGAGCCGCTTTGTCGCGATGATTACTTTCTTGACTTGTGTTGTCGGTTTGCGGATGCGGTGCCGAGG GTTGCCATGGTTTTGCGCTGCTTTCCTTCTTTCGCGAGGCCCTTCGTGGCCAAGTATCTTCCCGGAACGCGGCTC GTGCAGAAGCTGCGTGTCTTCGTCCTCGACGAGGTGACGTCCAGGAGAAAGTCTCGCCATGAGAATCCCATCAAG GATCTCCTCGACTTTGTCATGAACTGGGCCGATGAGCAACCGGAAGATTGGAGCGACTTGGAGGTGTCGGACATG ATCATCAACGTCTTGGTCACTCATACCATCTTCGAGCTCGCCACGCGCCCCGAATACGTGCCTGAGCTTCGCGAC GAGATACAGGAGTGTTTTCAGCTTCACGGCCAAGGCACAAAGGCGGCCGTCGACGCCATGCACAAGGTCGATAGC TTCATCAAGGAGACGCAGAGATGCAACGTTCTCGACGCCGCTGCCCTCGCAAGACTGGTGCTCAAGCCCTACACC TTCTCCAACGGACTACACATCCCACAAGGCACATACATCTTCACCCCCAACTCGCCCCTCCTCCAAGACGAGCGC TTCTACTCGGATCCAAACCGCTTCGACGGCCTCCGCTTCGCCCGAATGCGCAACGACGTCAAGCAGCGAGCCTCG TGTCCGCTGACGGCCACCAGCGAACACAGCATGCACTTTGGCATCGGCCGCAATGCCTGTCCCGGCCGCTTCATG GTCGCGGATGAGGTCAAGCTGGTCATGATTCACCTGCTGCTCAACATGGAGCTTGCTATGGAGGGGTTTGGGCCG AGGCCGAGGAACGTGGCGTTTGGCAAGTTTATGTTGCCGGATATGAGGGCTAGGATTTGGTTGAAGAGGGCGAGT TTTGCGCGGATTGAGTAG
Gene	>Ophcf2|04805 ATGGCCTCCCTCTCGGCAAAAGACGACTTCAAGGTCCTCATCATCGGTGGTTCCATCGCCGGCCTCACCCTCGCC CATTGTCTCGAGAAGCTCAAGGTTTCGTACGAGATACTCGAGCAGGGCCACGACATAAGCCCCCAGGTCGGGGCA TCAGTCGGTATCCTCCCCAACGGGGCCCAGGTGTTGGACCAGCTGGGCATCTTCGACGAGGTCGAGGAGGCTATC GAGCCTCTGACGTTTGCCCGTATCCGTTACCCGGATGGCTTCTTCTTCCACAGCCGGTATCCTTCGGTGCTACGG TCTCGGTGCGTCATGGTAACTTTGTTGACGTTGATGGGCGGGGCTGATTGAAAGGGGGGCCAGGTTCGGATACCC GCTTGCTTTTCTCGAACGGCGGCGTTTCCTCGAGATACTGTACGGGAAGCTCGAGGGCAAACATGACGTTCATAC GGGGCAGCGGGTGGTGAGGATTGATGACGAGGGCCATCGGGCTGTTGTTCGTACGGCCGACGGAAAGGAGTATAC GGGTGATTTGGTGGTTGGCGCCGATGGGTTGCACAGCATCGTGAGGTCTGAGATCTGGAGGCATGAGGCCGAGGC TGGGACGGGAGTCGTGACCACCAAGGAGAAAGAGAGTAAGTTAGACATCTGGTGAAGAAGAGACGGGAGAAAAGA ATACGATTAATACTGACAACCACGTCACAACCTCAAGGCTTGAGAATCGACTACGCCTGCGTCTTTGGCATCTCA TCCGGCGTCAAGGGCGTCCCAGCCGGTCTGCAACTCTCACTCCTAGATCACGGCTTAACAATCCACGTCTTCAAC GGCAAAGACACAAAGGCCTTTTGGTTCGTCATCATCAAGACGGACCGACGGTACGGCTACGGTCAACGCCCGCAG TACACCAATGACGACGCCCGCAAGACATGCGCAGCCATATCCTCAAAGGTCATCGACCATGGCCTCACCTTCGGT CACCTCTGGGATAGATGCCAGGTCTTCACCATGACGCCCCTGGAAGAAGGCAACTTCTCGACCTGGCACCGCGGA CGCCTCGTCTGCGTAGGCGACGCCGTCCGCAAGGTGACGCCCAACATAGGCCAAGGCGCCAACATGGCGATAGAA GACGTAGCCGTACTCGCAAACGCAATCTGGCGCCGATGCCGAAAGACGAAGCCGGCCTCCATCACGGCCGCCGTC TCGGAGATCCGCCTGGCTCGCACCCGCAGCGTGTGCCGGCAGTCGGAGATGCTGACGCGGATGCAGGCTCACGAG GGTCTTCTGAGGCGGGTGCTCGTCAGGAGGATTCTTCCCGCGCTGCACGATATCCCTGCTGGCTCTTCGGCTGTC GTTTTGGGGGGGGCTCAGAGCTTGGCTTTTGCGCCGAGGCCGGGGAGGGCCGGGAAAGGGGTTCGGCTTGGACTT TTGTCTGGACGGTTGGGAGGGCTTTTGCGCCGAAGCCGGTGGTTGTCTTGGTTGTCTTCCTTGTTGGGACGGTTG CCTGGGCGGTTGTGTGGGCGGTTGTGCGGCTCGATATGTTCAAGTTGTCTGCAGATTGATACATGTAAGTGCATG GGCACGGAGCAACGGCATGTTGAGTTTCTGAGGGGTGTTGATGGATAAGAAACAAGGGCATGTTGGTATACGTCA TGTCTCTTTAGGTAAACGATCTATAGGTTTGGCTACGTTCTCCCTTTTACAGTGACATGGAAGTGCATGTAACAA CATACGTCGAACATACATGTAGATAGACATCAATGATGCCTCATGGTGCGTACATACATACATACATGTGGTATC TGCAGCCGTGCAGTGTCCGTATAAGCCCTGGCCGGGAGATGACTGCATGACGACGTACCAGCTGCAGGCAAACGA ATCGTTGTCACGCCAGCGTACGTATCCGTAGGTTGAAGCGCGTAGAGACTCGTCTTCATGTGAGAGACATGAGAA TATTGAAGTCTGTGCGTAACTGACATGACCTAGCTGAGAGTCCAACACGTTCCCTGACATTGATTCCTCCCTCTC GTTCCATTCCCCTCTCCCCTTTCAACCCCCCCCCAGCATCTCACAGCCCGTCCGCAATGCTCAAGGAATTCACTC TGGCCAGCTTCGAGCCAGCATGGCCGCAAGCTACGGCTGCCGCGGCCCTCATCCTCGCTCTCATCTTCATCAGAC ACCTTGACTACGAAAAGACGGTTCGAGCTCTGCTTTCCATCGCCGCGAGATGGCTGCTGATGAGAGACGGGAAAG GTCAATGTACCCGTCGTCGGTCCCTGCGCCGGCCTCACCAAATGGGTAGCTGCTGTTCGTAACGTCTGGGCCGCT CGTGATTCCATTCACAAGGGTTATTCCAAGGCAAGTCGGCTTTGTCCGAGTGTTTGTCCCGTCCTCAAACTATCT CACTGACGCGGCTTGTCATACATAGTATGGCAAGTCGGCGTTCCAGATTCCCACCATGACCCGTATGGACGTCTT TCTCTGTGACCGGACCATGACGAGGGAGTATTACTCTCTCGACGAAGAGCACATGTCTTTCCAGGCTGCCATGTC CGAGGTATCAGCTCCCCCCCTTTTTTGAAGTGAAGCTTCACTACATTACAAAGAATGAGACTGAGGGAGCCGGAC TTCAACAGGAATTCCAGTTCAAGTACTCCCTGCCAGGCCAGCAACACGACATCCGCAAGATCCCAAACTCGGTAA TCGGCAAGGCCCTAAGCTGGCAAAGAAACCGATCCAACAATCCCCAAGACCCCTTCTTCGCCGACTTCTCCAAAG AGTTCCTCCACGGCTTCCAGCACGAGATGGAAGCCTTCCGTCGGAAGCAGCCGTCTTCCAGCCTGGCCTTCTTCT CGCACGCGGCCGAGCCCAAGGCCGAAGGGTGGATGGCGGTGCCTTGCTTCCCGCTGGCTTTGAAGATTGTGGCTC GGCTGACGACCAAGTCTCTCTTCGGGGAGCCGCTTTGTCGCGATGATTACTTTCTTGACTTGTGTTGTCGGTTTG CGGATGCGGTGCCGAGGGTTGCCATGGTTTTGCGCTGCTTTCCTTCTTTCGCGAGGCCGTGAGTTGTCTTTTTCA TGTTGTTGTCTTCGGCATGTTATCAGTTGGGGTTGAAGTTGTGGGCTGATGATTGGAGGTGACAGCTTCGTGGCC AAGTATCTTCCCGGAACGCGGCTCGTGCAGAAGCTGCGTGTCTTCGTCCTCGACGAGGTGACGTCCAGGAGAAAG TCTCGCCATGAGAATCCCATCAAGGTGAGACTCAGCCATGCCTGAAACCAGTCTTATACGGGAGAATACAAGTAC ATGAACTGACCAGCTCGGCAGGATCTCCTCGACTTTGTCATGAACTGGGCCGATGAGCAACCGGAAGATTGGAGC GACTTGGAGGTGTCGGACATGATCATCAACGTCGTCTTTGCCGCTCTGCACACTTCAAGCCAGGCGAGTTGACCA TGTTTGACCTCTCAGCAACAACATGATGGGACAGAAATCGTCAATAGTTCAAGGCTGACTATGTATTAAACCTAC TCAGTTGGTCACTCATACCATCTTCGAGCTCGCCACGCGCCCCGAATACGTGCCTGAGCTTCGCGACGAGATACA GGAGTGTTTTCAGCTTCACGGCCAAGGCACAAAGGCGGCCGTCGACGCCATGCACAAGGTCGATAGCTTCATCAA GGAGACGCAGAGATGCAACGTTCTCGACGCCGGTACGTCTCGAGTCTCCTTGTCATTGATGATACATGCAAACAT ACATGTAGTGTAAGTCTTTGACGAAGCTGACGATGCATCAACGTTTCAAATGACTCTCCAGCTGCCCTCGCAAGA CTGGTGCTCAAGCCCTACACCTTCTCCAACGGACTACACATCCCACAAGGCACATACATCTTCACCCCCAACTCG CCCCTCCTCCAAGACGAGCGCTTCTACTCGGATCCAAACCGCTTCGACGGCCTCCGCTTCGCCCGAATGCGCAAC GACGTCAAGCAGCGAGCCTCGTGTCCGCTGACGGCCACCAGCGAACACAGCATGCACTTTGGCATCGGCCGCAAT GCCTGTCCCGGCCGCTTCATGGTCGCGGATGAGGTCAAGCTGGTCATGATTCACCTGCTGCTCAACATGGAGCTT GCTATGGAGGGGTTTGGGCCGAGGCCGAGGAACGTGGCGTTTGGCAAGTTTATGTTGCCGGATATGAGGGCTAGG ATTTGGTTGAAGAGGGCGAGTTTTGCGCGGATTGAGTAG