Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Ophcf2|00855
Gene name
Location	scaffold_01:3294051..3298316
Strand	+
Gene length (bp)	4265
Transcript length (bp)	3405
Coding sequence length (bp)	3405
Protein length (aa)	1135

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00349	Hexokinase_1	Hexokinase	4.2E-76	593	804
PF03727	Hexokinase_2	Hexokinase	5.7E-75	814	1075
PF05631	MFS_5	Sugar-tranasporters, 12 TM	3.1E-31	86	272

GO

GO Term	Description	Terminal node
GO:0005524	ATP binding	Yes
GO:0016773	phosphotransferase activity, alcohol group as acceptor	Yes
GO:0015098	molybdate ion transmembrane transporter activity	Yes
GO:0015689	molybdate ion transport	Yes
GO:0005975	carbohydrate metabolic process	Yes
GO:0016021	integral component of membrane	Yes
GO:0022857	transmembrane transporter activity	No
GO:1901265	nucleoside phosphate binding	No
GO:0005215	transporter activity	No
GO:0015698	inorganic anion transport	No
GO:0032559	adenyl ribonucleotide binding	No
GO:0005488	binding	No
GO:0016740	transferase activity	No
GO:0031224	intrinsic component of membrane	No
GO:0015318	inorganic molecular entity transmembrane transporter activity	No
GO:0044238	primary metabolic process	No
GO:0008152	metabolic process	No
GO:1901363	heterocyclic compound binding	No
GO:0043168	anion binding	No
GO:0006810	transport	No
GO:0110165	cellular anatomical entity	No
GO:0016772	transferase activity, transferring phosphorus-containing groups	No
GO:0051234	establishment of localization	No
GO:0097159	organic cyclic compound binding	No
GO:0000166	nucleotide binding	No
GO:0008509	anion transmembrane transporter activity	No
GO:0051179	localization	No
GO:0035639	purine ribonucleoside triphosphate binding	No
GO:0097367	carbohydrate derivative binding	No
GO:0030554	adenyl nucleotide binding	No
GO:0008150	biological_process	No
GO:0043167	ion binding	No
GO:0006811	ion transport	No
GO:0036094	small molecule binding	No
GO:0003824	catalytic activity	No
GO:0032555	purine ribonucleotide binding	No
GO:0015075	ion transmembrane transporter activity	No
GO:0015103	inorganic anion transmembrane transporter activity	No
GO:0017076	purine nucleotide binding	No
GO:0032553	ribonucleotide binding	No
GO:0003674	molecular_function	No
GO:0006820	anion transport	No
GO:0005575	cellular_component	No
GO:0071704	organic substance metabolic process	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 11	0.5

Transmembrane Domains

Domain #	Start	End	Length
1	4	21	17
2	86	108	22
3	155	177	22
4	210	232	22
5	247	269	22
6	302	324	22
7	1108	1130	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Expression analysis during behavioral modification. Published in: Will et al., G3, 2020

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Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Ophcf2|00855 MSFYAANLAALCAINAFLLYRRYRHRRPQMTPISAARLETAQRFQRRFLAPYALAVAADWLQASLGSQQDVVARL YATGFVSAAALLGRVSGGIATTLLFSAFESWMISDYHLLELDDSVLSLKTVLENMALVNSAVAMVSGVAGDVLVE ASGLRAAPFVAASLCCLIAAPLLLMSWRENTRGGPVVKGRWRDYRLGIVTVVKSRSVSALAIATCCFEGAMYLFV FFWTAALNSARLKAGIETEPPLGLIFSSFMCAMMAGSLVSTPVMAPSRQSATTDLCLTMAIGSSSLSCAVLFDDE RIVFWAFCVLEATVGAYFPVMGFLKSELVDDDRRGHVYSALRLPLNLFVLVAHSLDEEGDKHRVRVFLTLAGLLP AASVLKQDYRRVIVSVGRSGSGGSYSGGFVGADRQSADRQSAVAGPIPTPEDGSGEDCLRTKDDPPKGQPRSRSR SRSRSRSRSRSRSRSRSRSRSRSRSNCSETTLDEGRVTLRNRQPSTNESHRQPPPPTTVTTSSHASWRHGLLSAL VLAATATFILGDAKLLLLQPVIFLFRASHHLIFHLSSEPAPVCLNPASFATLPPVSRPLAMALADETTRVVSQFD FSDADVNRHVAEFLQQMNDGLEKEDTSISQIPTYVTGVPNGTEKGLYLAVDLGGTNFRVCSITLNGDTTFNLTYS KVAIPKKLMVADTARELFAFLAKQIELFLREHHAEHFESHVRRRNTSSTPLGYRDEHIFRLGFTFSFPVKQLGIN KGRLIRWTKGFDIPDAIGKDVCALLQQEIDVLRLPVKVAALVNDTVGTLMARSYTSNGKHRSILGGIFGTGTNGA YIEKTTNIKKRIEGDFDTSTGEMVVNTEWGSFDNQLNVLPSTPWDTKLDAQSVNPGFQMFEKRVSGMFLGELVRL ATIDMMKNDATSLFKDVNSSFNDWGTTTNISSQSGMLKAWGLDSAIMSVAASDNSPELSTLRQELENVLQVYNPS LEDAQAFKAVCGAVARRAARLSAVAIGAVALKSGKIDDPDEDVIDIGVDGSLVEHYPFFRDMIYEALLAVDGIGP EGVKKIRIGIAKDGSGVGAALIALVAQRMEKPGDFLADLRMDIRRSMEAMSKAEEETALPAVAYVAAGILGIAAV AAIWWNRRR*
Coding	>Ophcf2|00855 ATGAGCTTTTACGCCGCAAACCTCGCCGCGCTATGTGCCATCAACGCCTTCCTCCTCTATCGAAGATATCGACAT CGACGTCCTCAGATGACGCCCATCAGTGCCGCGCGCCTGGAGACGGCTCAAAGGTTCCAGCGACGCTTCCTCGCG CCATATGCTCTCGCCGTCGCCGCCGACTGGTTGCAGGCCAGTCTTGGCTCGCAGCAGGACGTCGTCGCGCGCCTC TACGCCACCGGCTTTGTGTCCGCCGCTGCGTTGCTCGGCCGCGTTTCGGGCGGTATCGCGACCACTCTTCTCTTC AGCGCCTTCGAATCTTGGATGATCTCGGACTACCACCTGTTGGAGCTTGATGATTCGGTCCTGTCGCTCAAGACA GTTCTTGAGAATATGGCGCTCGTCAACAGCGCCGTCGCCATGGTTTCGGGCGTTGCGGGCGATGTCCTCGTCGAG GCGTCTGGGTTGCGAGCCGCGCCATTTGTAGCCGCCAGTCTTTGCTGTCTGATTGCTGCTCCCCTGCTGCTGATG TCATGGCGCGAGAACACACGCGGCGGCCCCGTCGTCAAGGGCCGATGGAGGGACTATCGGCTCGGCATCGTGACG GTCGTGAAGAGCAGGAGTGTCTCGGCTCTGGCCATTGCCACATGTTGCTTCGAAGGGGCCATGTACCTCTTCGTC TTTTTCTGGACCGCGGCTCTCAATAGTGCTCGTCTCAAAGCCGGCATCGAGACGGAGCCACCGTTAGGACTCATC TTCTCGAGCTTCATGTGCGCCATGATGGCCGGTTCCCTGGTCTCGACGCCAGTCATGGCCCCCTCGCGACAGAGC GCGACTACGGATCTGTGCCTGACCATGGCCATCGGCAGCAGCAGCCTATCTTGCGCCGTGCTCTTTGACGACGAA CGGATCGTCTTCTGGGCATTTTGCGTCCTCGAGGCTACCGTCGGCGCATACTTTCCCGTCATGGGCTTTCTGAAG AGCGAACTCGTCGACGACGATAGGCGAGGCCATGTGTACAGCGCTCTCCGTCTTCCTCTGAACCTGTTCGTCCTG GTGGCGCATAGCCTGGACGAGGAGGGTGACAAGCACCGTGTCCGGGTGTTTCTGACGCTCGCCGGGCTTTTGCCG GCAGCATCCGTATTGAAGCAGGACTATCGCCGTGTCATCGTTTCCGTCGGCCGCTCCGGGTCCGGCGGTAGCTAC AGTGGGGGCTTCGTCGGCGCCGACCGTCAATCCGCCGACCGTCAATCCGCCGTTGCCGGCCCGATTCCGACGCCG GAGGATGGCTCGGGAGAGGACTGCTTGCGAACGAAGGACGACCCACCAAAGGGGCAGCCCAGAAGCAGGAGCAGG AGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGC AACTGCAGCGAGACGACGTTAGATGAAGGCCGCGTTACGCTGCGAAATCGTCAACCATCGACAAACGAGTCACAC CGTCAACCACCACCGCCAACCACCGTCACGACGTCTTCCCACGCTTCGTGGCGGCACGGCCTGCTCTCGGCCTTG GTGCTGGCGGCGACGGCGACGTTCATCCTCGGCGACGCCAAGCTGCTCCTCCTCCAGCCCGTGATCTTCCTCTTC CGCGCCTCACATCATCTCATCTTTCATCTGTCATCGGAGCCGGCGCCCGTTTGCCTCAACCCCGCATCCTTTGCG ACGCTGCCTCCCGTCTCGCGCCCTCTCGCCATGGCGCTGGCCGACGAGACGACCCGAGTCGTCTCTCAGTTTGAT TTCTCCGACGCAGATGTCAATCGTCACGTGGCAGAGTTTCTACAGCAGATGAATGATGGACTGGAAAAGGAAGAC ACCAGCATCAGCCAGATTCCGACATATGTTACGGGTGTCCCCAATGGCACCGAAAAGGGCCTCTACTTGGCCGTC GACCTGGGCGGCACCAATTTCCGAGTCTGCTCCATCACGCTCAACGGAGACACCACCTTCAACCTGACGTATAGC AAGGTGGCCATACCCAAGAAGCTCATGGTGGCCGACACTGCCAGAGAGCTGTTCGCCTTCCTCGCCAAGCAGATC GAGCTCTTCCTCCGTGAGCATCACGCCGAGCACTTTGAGAGCCACGTGCGTCGGCGCAACACGTCGAGCACACCC CTGGGCTACCGCGACGAACACATCTTCCGCCTCGGCTTCACCTTTAGCTTCCCCGTCAAGCAGCTCGGCATCAAC AAGGGACGGCTCATAAGATGGACAAAGGGCTTCGACATTCCCGACGCCATCGGCAAGGACGTCTGCGCCCTACTG CAGCAGGAGATTGACGTGCTCCGACTCCCCGTCAAGGTGGCGGCCCTCGTCAACGACACCGTCGGAACCCTGATG GCGCGCTCCTATACGTCCAACGGTAAGCATCGATCCATTCTAGGCGGCATCTTTGGCACCGGCACCAATGGCGCC TACATTGAGAAGACGACCAACATCAAGAAGCGCATCGAGGGCGACTTCGACACGTCAACGGGCGAGATGGTCGTC AACACGGAATGGGGCTCCTTTGACAATCAGCTCAACGTGCTGCCGTCGACGCCGTGGGACACGAAGCTCGACGCC CAGAGCGTTAACCCGGGCTTCCAGATGTTCGAGAAGCGCGTGTCGGGCATGTTTCTAGGCGAGCTCGTGCGGTTG GCCACGATTGACATGATGAAGAATGACGCCACCTCGCTTTTCAAGGACGTCAACTCGAGCTTCAACGATTGGGGC ACGACGACAAACATCAGTTCACAGTCGGGCATGCTCAAGGCCTGGGGCCTCGACAGCGCCATCATGTCCGTGGCC GCGTCGGACAACAGCCCCGAGCTGTCGACGCTGCGGCAGGAGCTCGAGAACGTGCTCCAGGTCTACAACCCGTCG CTCGAGGACGCCCAGGCCTTCAAGGCCGTCTGCGGAGCCGTCGCTCGACGGGCAGCAAGGCTATCGGCGGTTGCC ATTGGCGCCGTCGCCCTCAAGTCGGGAAAGATTGACGACCCGGACGAGGACGTCATCGATATCGGCGTCGACGGC AGCCTCGTCGAGCACTACCCGTTTTTCCGCGACATGATCTACGAAGCCCTGCTCGCCGTCGACGGCATCGGACCT GAGGGCGTCAAGAAGATTCGTATCGGCATCGCCAAGGACGGCAGCGGCGTCGGCGCCGCCCTCATCGCCCTCGTC GCGCAGCGGATGGAGAAGCCGGGGGATTTCCTCGCCGATCTGAGGATGGACATTCGGCGCAGTATGGAGGCCATG TCCAAGGCTGAGGAGGAAACGGCGCTGCCGGCAGTGGCATACGTGGCGGCTGGCATCCTCGGCATTGCTGCTGTA GCGGCCATCTGGTGGAACAGACGACGATAG
Transcript	>Ophcf2|00855 ATGAGCTTTTACGCCGCAAACCTCGCCGCGCTATGTGCCATCAACGCCTTCCTCCTCTATCGAAGATATCGACAT CGACGTCCTCAGATGACGCCCATCAGTGCCGCGCGCCTGGAGACGGCTCAAAGGTTCCAGCGACGCTTCCTCGCG CCATATGCTCTCGCCGTCGCCGCCGACTGGTTGCAGGCCAGTCTTGGCTCGCAGCAGGACGTCGTCGCGCGCCTC TACGCCACCGGCTTTGTGTCCGCCGCTGCGTTGCTCGGCCGCGTTTCGGGCGGTATCGCGACCACTCTTCTCTTC AGCGCCTTCGAATCTTGGATGATCTCGGACTACCACCTGTTGGAGCTTGATGATTCGGTCCTGTCGCTCAAGACA GTTCTTGAGAATATGGCGCTCGTCAACAGCGCCGTCGCCATGGTTTCGGGCGTTGCGGGCGATGTCCTCGTCGAG GCGTCTGGGTTGCGAGCCGCGCCATTTGTAGCCGCCAGTCTTTGCTGTCTGATTGCTGCTCCCCTGCTGCTGATG TCATGGCGCGAGAACACACGCGGCGGCCCCGTCGTCAAGGGCCGATGGAGGGACTATCGGCTCGGCATCGTGACG GTCGTGAAGAGCAGGAGTGTCTCGGCTCTGGCCATTGCCACATGTTGCTTCGAAGGGGCCATGTACCTCTTCGTC TTTTTCTGGACCGCGGCTCTCAATAGTGCTCGTCTCAAAGCCGGCATCGAGACGGAGCCACCGTTAGGACTCATC TTCTCGAGCTTCATGTGCGCCATGATGGCCGGTTCCCTGGTCTCGACGCCAGTCATGGCCCCCTCGCGACAGAGC GCGACTACGGATCTGTGCCTGACCATGGCCATCGGCAGCAGCAGCCTATCTTGCGCCGTGCTCTTTGACGACGAA CGGATCGTCTTCTGGGCATTTTGCGTCCTCGAGGCTACCGTCGGCGCATACTTTCCCGTCATGGGCTTTCTGAAG AGCGAACTCGTCGACGACGATAGGCGAGGCCATGTGTACAGCGCTCTCCGTCTTCCTCTGAACCTGTTCGTCCTG GTGGCGCATAGCCTGGACGAGGAGGGTGACAAGCACCGTGTCCGGGTGTTTCTGACGCTCGCCGGGCTTTTGCCG GCAGCATCCGTATTGAAGCAGGACTATCGCCGTGTCATCGTTTCCGTCGGCCGCTCCGGGTCCGGCGGTAGCTAC AGTGGGGGCTTCGTCGGCGCCGACCGTCAATCCGCCGACCGTCAATCCGCCGTTGCCGGCCCGATTCCGACGCCG GAGGATGGCTCGGGAGAGGACTGCTTGCGAACGAAGGACGACCCACCAAAGGGGCAGCCCAGAAGCAGGAGCAGG AGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGC AACTGCAGCGAGACGACGTTAGATGAAGGCCGCGTTACGCTGCGAAATCGTCAACCATCGACAAACGAGTCACAC CGTCAACCACCACCGCCAACCACCGTCACGACGTCTTCCCACGCTTCGTGGCGGCACGGCCTGCTCTCGGCCTTG GTGCTGGCGGCGACGGCGACGTTCATCCTCGGCGACGCCAAGCTGCTCCTCCTCCAGCCCGTGATCTTCCTCTTC CGCGCCTCACATCATCTCATCTTTCATCTGTCATCGGAGCCGGCGCCCGTTTGCCTCAACCCCGCATCCTTTGCG ACGCTGCCTCCCGTCTCGCGCCCTCTCGCCATGGCGCTGGCCGACGAGACGACCCGAGTCGTCTCTCAGTTTGAT TTCTCCGACGCAGATGTCAATCGTCACGTGGCAGAGTTTCTACAGCAGATGAATGATGGACTGGAAAAGGAAGAC ACCAGCATCAGCCAGATTCCGACATATGTTACGGGTGTCCCCAATGGCACCGAAAAGGGCCTCTACTTGGCCGTC GACCTGGGCGGCACCAATTTCCGAGTCTGCTCCATCACGCTCAACGGAGACACCACCTTCAACCTGACGTATAGC AAGGTGGCCATACCCAAGAAGCTCATGGTGGCCGACACTGCCAGAGAGCTGTTCGCCTTCCTCGCCAAGCAGATC GAGCTCTTCCTCCGTGAGCATCACGCCGAGCACTTTGAGAGCCACGTGCGTCGGCGCAACACGTCGAGCACACCC CTGGGCTACCGCGACGAACACATCTTCCGCCTCGGCTTCACCTTTAGCTTCCCCGTCAAGCAGCTCGGCATCAAC AAGGGACGGCTCATAAGATGGACAAAGGGCTTCGACATTCCCGACGCCATCGGCAAGGACGTCTGCGCCCTACTG CAGCAGGAGATTGACGTGCTCCGACTCCCCGTCAAGGTGGCGGCCCTCGTCAACGACACCGTCGGAACCCTGATG GCGCGCTCCTATACGTCCAACGGTAAGCATCGATCCATTCTAGGCGGCATCTTTGGCACCGGCACCAATGGCGCC TACATTGAGAAGACGACCAACATCAAGAAGCGCATCGAGGGCGACTTCGACACGTCAACGGGCGAGATGGTCGTC AACACGGAATGGGGCTCCTTTGACAATCAGCTCAACGTGCTGCCGTCGACGCCGTGGGACACGAAGCTCGACGCC CAGAGCGTTAACCCGGGCTTCCAGATGTTCGAGAAGCGCGTGTCGGGCATGTTTCTAGGCGAGCTCGTGCGGTTG GCCACGATTGACATGATGAAGAATGACGCCACCTCGCTTTTCAAGGACGTCAACTCGAGCTTCAACGATTGGGGC ACGACGACAAACATCAGTTCACAGTCGGGCATGCTCAAGGCCTGGGGCCTCGACAGCGCCATCATGTCCGTGGCC GCGTCGGACAACAGCCCCGAGCTGTCGACGCTGCGGCAGGAGCTCGAGAACGTGCTCCAGGTCTACAACCCGTCG CTCGAGGACGCCCAGGCCTTCAAGGCCGTCTGCGGAGCCGTCGCTCGACGGGCAGCAAGGCTATCGGCGGTTGCC ATTGGCGCCGTCGCCCTCAAGTCGGGAAAGATTGACGACCCGGACGAGGACGTCATCGATATCGGCGTCGACGGC AGCCTCGTCGAGCACTACCCGTTTTTCCGCGACATGATCTACGAAGCCCTGCTCGCCGTCGACGGCATCGGACCT GAGGGCGTCAAGAAGATTCGTATCGGCATCGCCAAGGACGGCAGCGGCGTCGGCGCCGCCCTCATCGCCCTCGTC GCGCAGCGGATGGAGAAGCCGGGGGATTTCCTCGCCGATCTGAGGATGGACATTCGGCGCAGTATGGAGGCCATG TCCAAGGCTGAGGAGGAAACGGCGCTGCCGGCAGTGGCATACGTGGCGGCTGGCATCCTCGGCATTGCTGCTGTA GCGGCCATCTGGTGGAACAGACGACGATAG
Gene	>Ophcf2|00855 ATGAGCTTTTACGCCGCAAACCTCGCCGCGCTATGTGCCATCAACGCCTTCCTCCTCTATCGAAGATATCGACAT CGACGTCCTCAGATGACGCCCATCAGTGCCGCGCGCCTGGAGACGGCTCAAAGGTTCCAGCGACGCTTCCTCGCG CCATATGCTCTCGCCGTCGCCGCCGACTGGTTGCAGGCCAGTCTTGGCTCGCAGCGTCGGTAGACTCTCGACTGA CGCGAGCGCCTCCAGGGTCCGCACCTGTACGCATTGTATAGGACTGACAAGCAGCTGCCAGAGGACGTCGTCGCG CGCCTCTACGCCACCGGCTTTGTGTCCGCCGCTGCGTGTGCCGTTGTCGCTGGACGGCTGGTAGACAGCCTCGGC AGACGTTCCGCATGTCTACTTTATTGCATTCTAAGTGGCCTTGCCTGTGGCTTGATGCTTTGCAGAAGCATGCCG CTCCTAGTGCTCGGCCGCGTTTCGGGCGGTATCGCGACCACTCTTCTCTTCAGCGCCTTCGAATCTTGGATGATC TCGGACTACCACCTGTTGGAGCTTGATGATTCGGTCCTGTCGCTCAAGACAGTTCTTGAGAATATGGCGCTCGTC AACAGCGCCGTCGCCATGGTTTCGGGCGTTGCGGGCGATGTCCTCGTCGAGGCGTCTGGGTTGCGAGCCGCGCCA TTTGTAGCCGCCAGTCTTTGCTGTCTGATTGCTGCTCCCCTGCTGCTGATGTCATGGCGCGAGAACACACGCGGC GGCCCCGTCGTCAAGGGCCGATGGAGGGACTATCGGCTCGGCATCGTGACGGTCGTGAAGAGCAGGAGTGTCTCG GCTCTGGCCATTGCCACATGTTGCTTCGAAGGGGCCATGTACCTCTTCGTCTTTTTCTGGACCGCGGCTCTCAAT AGTGCTCGTCTCAAAGCCGGCATCGAGACGGAGCCACCGTTAGGACTCATCTTCTCGAGCTTCATGTGCGCCATG ATGGCCGGTTCCCTGGTCTCGACGCCAGTCATGGCCCCCTCGCGACAGAGCGCGACTACGGATCTGTGCCTGACC ATGGCCATCGGCAGCAGCAGCCTATCTTGCGCCGTGCTCTTTGACGACGAACGGATCGTCTTCTGGGCATTTTGC GTCCTCGAGGCTACCGTCGGCGCATACTTTCCCGTCATGGGCTTTCTGAAGAGCGAACTCGTCGACGACGATAGG CGAGGCCATGTGTACAGCGCTCTCCGTCTTCCTCTGAACCTGTTCGTCCTGGTGGCGCATAGCCTGGACGAGGAG GGTAGGTGACGGAAGACGTGCTCTGGACGAACCCTTGGACCTGCGAGGCTGACTCGAGGCTGAGCAGGTGACAAG CACCGTGTCCGGGTGTTTCTGACGCTCGCCGGGCTTTTGGTAGCGGCTTCGATAGTAGTCAAACGAGGCCTGACC TGAAGCGGCGGAGACTGACAGATGACTGGCCATCTGCGAGGGGCGGAAGAAGTGAAGGGAAATGTTAGTGAGCTA TTGCGGCGCGTATCTCGTCTGCGGCTAGTCATTAGAGCCGCCCACAGAAGCCATTGAGACTGTCTCGCCTTCCTT TTGCTTCTACGAATACGAATGCCTGTCATTGCTTGGACCTACCTCTCCTCTTTCTCCTCTTATATCAAAGAACAG CCGGCAGCATCCGTATTGAAGCAGGACTATCGCCGTGTCATCGTTTCCGTCGGCCGCTCCGGGTCCGGCGGTAGC TACAGTGGGGGCTTCGTCGGCGCCGACCGTCAATCCGCCGACCGTCAATCCGCCGTTGCCGGCCCGATTCCGACG CCGGAGGATGGCTCGGGAGAGGACTGCTTGCGAACGAAGGACGACCCACCAAAGGGGCAGCCCAGAAGCAGGAGC AGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGGAGCAGAAGCAGGAGCAGG AGCAACTGCAGCGAGACGACGTTAGATGAAGGCCGCGTTACGCTGCGAAATCGTCAACCATCGACAAACGAGTCA CACCGTCAACCACCACCGCCAACCACCGTCACGACGTCTTCCCACGCTTCGTGGCGGCACGGCCTGCTCTCGGCC TTGGTGCTGGCGGCGACGGCGACGGTGAGTTTGGCACTTTTTTTTTTTTTTTTTTTTCGCGCCCTCTTCCCACTT TCTTTCTCAAAATGAAGAAACCGTTGGAAACCCCCGCATGGGGCCCCATGATCCTGGCAATGTGCAAGGCGCGTC GCACAAACACTGTGCTAACTTGCGGCAGTTCATCCTCGGCGACGCCAAGCTGCTCCTCCTCCAGCCCGTGATCTT CCTCTTCCGCGCCTCACATCATCTCATCTTTCATCTGTCATCGGAGCCGGCGCCCGTTTGCCTCAACCCCGCATC CTTTGCGACGCTGCCTCCCGTCTCGCGCCCTCTCGCCATGGCGCTGGCCGACGAGACGACCCGAGTCGTCTCTCA GTTTGATTTCTCCGACGCAGATGTCAATCGTCACGTGGCAGAGTTTCTACAGCAGATGAGTGAGTCTCTTTCTCT CTCCCTTGCTGCTTCTGGTCCGCCTGCTCTTACACGCCTAGATGATGGACTGGAAAAGGAAGACACCAGCATCAG CCAGATTCCGACATATGTTACGGGTGTCCCCAATGGCACCGAAAAGGTCGCCCTCCTCGTCCATCTCCACGATTC ATAGCGACGCTGACTCTCTTGAAAAAAGGGCCTCTACTTGGCCGTCGACCTGGGCGGCACCAATTTCCGAGTCTG CTCCATCACGCTCAACGGAGACACCACCTTCAACCTGACGTATAGCAAGGTGGCCATACCCAAGAAGCTCATGGT GGCCGACACTGCCAGAGAGCTGTTCGCCTTCCTCGCCAAGCAGATCGAGCTCTTCCTCCGTGAGCATCACGCCGA GCACTTTGAGAGCCACGTGCGTCGGCGCAACACGTCGAGCACACCCCTGGGCTACCGCGACGAACACATCTTCCG CCTCGGCTTCACCTTTAGCTTCCCCGTCAAGCAGCTCGGCATCAACAAGGGACGGCTCATAAGATGGACAAAGGG CTTCGACATTCCCGACGCCATCGGCAAGGACGTCTGCGCCCTACTGCAGCAGGAGATTGACGTGCTCCGACTCCC CGTCAAGGTGGCGGCCCTCGTCAACGACACCGTCGGAACCCTGATGGCGCGCTCCTATACGTCCAACGGTAAGCA TCGATCCATTCTAGGCGGCATCTTTGGCACCGGCACCAATGGCGCCTACATTGAGAAGACGACCAACATCAAGAA GCGCATCGAGGGCGACTTCGACACGTCAACGGGCGAGATGGTCGTCAACACGGAATGGGGCTCCTTTGACAATCA GCTCAACGTGCTGCCGTCGACGCCGTGGGACACGAAGCTCGACGCCCAGAGCGTTAACCCGGGCTTCCAGATGTT CGAGAAGCGCGTGTCGGGCATGTTTCTAGGCGAGCTCGTGCGGTTGGCCACGATTGACATGATGAAGAATGACGC CACCTCGCTTTTCAAGGACGTCAACTCGAGCTTCAACGATTGGGGCACGACGACAAACATCAGTTCACAGTCGGG CATGCTCAAGGCCTGGGGCCTCGACAGCGCCATCATGTCCGTGGCCGCGTCGGACAACAGCCCCGAGCTGTCGAC GCTGCGGCAGGAGCTCGAGAACGTGCTCCAGGTCTACAACCCGTCGCTCGAGGACGCCCAGGCCTTCAAGGCCGT CTGCGGAGCCGTCGCTCGACGGGCAGCAAGGCTATCGGCGGTTGCCATTGGCGCCGTCGCCCTCAAGTCGGGAAA GATTGACGACCCGGACGAGGACGTCATCGATATCGGCGTCGACGGCAGCCTCGTCGAGCACTACCCGTTTTTCCG CGACATGATCTACGAAGCCCTGCTCGCCGTCGACGGCATCGGACCTGAGGGCGTCAAGAAGATTCGTATCGGCAT CGCCAAGGACGGCAGCGGCGTCGGCGCCGCCCTCATCGCCCTCGTCGCGCAGCGGATGGAGAAGCCGGGGGATTT CCTCGCCGATCTGAGGATGGACATTCGGCGCAGTATGGAGGCCATGTCCAAGGCTGGTGCGTATCCCTTGAGTCG GACGTCTATTCATCTCACAATGTCCTCCGTGCTGACTTCACCCAGAGGAGGAAACGGCGCTGCCGGCAGTGGCAT ACGTGGCGGCTGGCATCCTCGGCATTGCTGCTGTAGCGGCCATCTGGTGGAACAGACGACGATAG