© 2023 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | OphauG2|7764 |
| Gene name | |
| Location | Contig_94:9125..12498 |
| Strand | + |
| Gene length (bp) | 3373 |
| Transcript length (bp) | 3189 |
| Coding sequence length (bp) | 3189 |
| Protein length (aa) | 1063 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF07993 | NAD_binding_4 | Male sterility protein | 1.7E-34 | 688 | 925 |
| PF00501 | AMP-binding | AMP-binding enzyme | 7.0E-30 | 22 | 341 |
| PF01370 | Epimerase | NAD dependent epimerase/dehydratase family | 1.8E-12 | 686 | 895 |
| PF00550 | PP-binding | Phosphopantetheine attachment site | 1.7E-09 | 568 | 628 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O74298|LYS2_PENCH | L-2-aminoadipate reductase large subunit OS=Penicillium chrysogenum GN=lys2 PE=3 SV=1 | 565 | 928 | 1.0E-23 |
| sp|P07702|LYS2_YEAST | L-2-aminoadipate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS2 PE=1 SV=2 | 582 | 931 | 3.0E-22 |
| sp|P40976|LYS2_SCHPO | L-2-aminoadipate reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lys1 PE=1 SV=3 | 554 | 927 | 1.0E-20 |
| sp|Q70LM4|LGRD_BREPA | Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis GN=lgrD PE=1 SV=1 | 586 | 1000 | 3.0E-20 |
| sp|Q6FMI5|LYS2_CANGA | L-2-aminoadipate reductase large subunit OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=LYS2 PE=3 SV=1 | 501 | 949 | 4.0E-20 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O74298|LYS2_PENCH | L-2-aminoadipate reductase large subunit OS=Penicillium chrysogenum GN=lys2 PE=3 SV=1 | 565 | 928 | 1.0E-23 |
| sp|P07702|LYS2_YEAST | L-2-aminoadipate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS2 PE=1 SV=2 | 582 | 931 | 3.0E-22 |
| sp|P40976|LYS2_SCHPO | L-2-aminoadipate reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lys1 PE=1 SV=3 | 554 | 927 | 1.0E-20 |
| sp|Q70LM4|LGRD_BREPA | Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis GN=lgrD PE=1 SV=1 | 586 | 1000 | 3.0E-20 |
| sp|Q6FMI5|LYS2_CANGA | L-2-aminoadipate reductase large subunit OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=LYS2 PE=3 SV=1 | 501 | 949 | 4.0E-20 |
| sp|Q6RKB1|CAR_NOCIO | Carboxylic acid reductase OS=Nocardia iowensis GN=car PE=1 SV=1 | 41 | 949 | 5.0E-19 |
| sp|B2HN69|CAR_MYCMM | Carboxylic acid reductase OS=Mycobacterium marinum (strain ATCC BAA-535 / M) GN=car PE=1 SV=1 | 373 | 949 | 4.0E-16 |
| sp|Q75BB3|LYS2_ASHGO | L-2-aminoadipate reductase large subunit OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=LYS2 PE=3 SV=2 | 584 | 939 | 2.0E-15 |
| sp|P37693|HETM_NOSS1 | Polyketide synthase HetM OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=hetM PE=3 SV=1 | 576 | 944 | 2.0E-12 |
| sp|B0G138|PKS21_DICDI | Probable polyketide synthase 21 OS=Dictyostelium discoideum GN=pks21 PE=3 SV=1 | 664 | 863 | 6.0E-12 |
| sp|Q54T36|PKS19_DICDI | Probable polyketide synthase 19 OS=Dictyostelium discoideum GN=pks19 PE=3 SV=1 | 664 | 863 | 5.0E-11 |
| sp|Q86AE3|PKS9_DICDI | Probable polyketide synthase 9/36 OS=Dictyostelium discoideum GN=pks9 PE=2 SV=1 | 561 | 872 | 2.0E-10 |
| sp|B0G0Z9|PKS6_DICDI | Probable polyketide synthase 6 OS=Dictyostelium discoideum GN=pks6 PE=3 SV=1 | 551 | 922 | 2.0E-09 |
| sp|Q4WAZ9|NRP14_ASPFU | Nonribosomal peptide synthetase 14 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=NRPS14 PE=2 SV=2 | 417 | 910 | 5.0E-09 |
| sp|P9WQ37|FAC13_MYCTU | Long-chain-fatty-acid--CoA ligase FadD13 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=fadD13 PE=1 SV=1 | 147 | 454 | 9.0E-09 |
| sp|P9WQ36|FAC13_MYCTO | Long-chain-fatty-acid--CoA ligase FadD13 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=fadD13 PE=3 SV=1 | 147 | 454 | 9.0E-09 |
| sp|Q54TW0|PKS18_DICDI | Probable polyketide synthase 18 OS=Dictyostelium discoideum GN=pks18 PE=2 SV=1 | 674 | 911 | 1.0E-08 |
| sp|Q55CN6|PKS3_DICDI | Probable polyketide synthase 3 OS=Dictyostelium discoideum GN=pks3 PE=3 SV=1 | 680 | 863 | 6.0E-08 |
| sp|Q12572|LYS2_CANAX | L-2-aminoadipate reductase large subunit OS=Candida albicans GN=LYS2 PE=3 SV=2 | 686 | 957 | 5.0E-07 |
| sp|A1CLY8|CCSA_ASPCL | Polyketide synthase-nonribosomal peptide synthetase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=ccsA PE=3 SV=1 | 585 | 987 | 1.0E-06 |
| sp|Q8VCW8|ACSF2_MOUSE | Acyl-CoA synthetase family member 2, mitochondrial OS=Mus musculus GN=Acsf2 PE=1 SV=1 | 171 | 461 | 2.0E-06 |
| sp|Q558Y6|PKS14_DICDI | Probable polyketide synthase 14 OS=Dictyostelium discoideum GN=pks14 PE=3 SV=2 | 686 | 973 | 2.0E-06 |
| sp|Q4WF61|NRPS3_ASPFU | Nonribosomal peptide synthetase 3 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=NRPS3 PE=2 SV=2 | 10 | 605 | 6.0E-06 |
| sp|Q54FP8|PKS32_DICDI | Probable polyketide synthase 32 OS=Dictyostelium discoideum GN=pks32 PE=3 SV=1 | 687 | 930 | 6.0E-06 |
| Gene cluster ID | Type of secondary metabolism gene |
|---|---|
| Cluster 29 | NRPS-like |
| Orthofinder run ID | 4 |
| Orthogroup | 69 |
| Change Orthofinder run |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >OphauG2|7764 MSQALGSQRLLTEIIDHLSETEPDATWLEYPKSTSDYAAGFNAITYRALANAVNGLAWHLHRNVEKTSEFQTIAY IGQNDARYALMLYACIKAGFKVFFTSPKNSVSTHLGLFSTLQCSILVTTRPTPAIVEDISSAHSMQVVFIPSLEE LLEKHYETFPCNKTFADARSEPFLVLHTSGSTSSPKALVYTHEFVSRNISALQLSTPMEFFSVYQLYLGSRYISL FPLFHMAGYWLACVATLFSRATVILPSPSSPPTGDTLYAMLHHTTANWAAVSPVTVDSIGRNPEALQFISENLER LIFAGGNPSVAMGNKVSSKIKICNLYGSSECGGCAHLIPNDNADEHSERLWSYISIQSQTNPVFEEHTPGLYELV IKRDPLCEAYQPVFEQRPELQEFRTSDLFAPHPKVPGFWQHRGRIDDTIVFLSGEKTNPLSFESFVLDHPDVSGA LVFGTNRMEAGILIELADTEQSQLLLHDKKEAIDNLWPRIDMANSSAPVYARIAESHVCFVSPKKPMLRSGKGTI RRQDTIRLYAEEIEEIYKESELLNGQSESRSIDINNIDEIAQAIRSAFAIVTKRDIPDDADFFSIGMDSVQVIRL VRQLRRVTGLADITPALVYKNPSISTLSLEIAKSASSNAKENSSVTGVERLQVLEQTIQEYKGKIAELMQATKNS HAQSSQQQSTILVTGTTGYIGSYILNSLLAHPSSPKIICLNRSADSVHVQASRNKLRDESLATHFPADRVKFLSS TDTSNAQLGLSDLEYQHLLRQVTLVIHNAWPVDFNLPLSAFRASLDGLVGIIELCKTGNYSPSLIFVSSISVAMN LQAQYISEAIIDNLEAPTPGYGESKFVAEHMLFEASRKLNFKASVVRVGQVSGAAYSPGRWNRRDWLPRMVLSSR YIGAIPKHLGVLNKIEWIPIDVLSKFVIEISTKLGFDSSFEVYHAINPHVTTWQKLLPTVIQALDTESPATEKST MDCISPTEWVERLRQSSVDFASDKDDEQIDTRNPALKLLDFFDETFQIEASEKVDWSTEVSVKMSETLRRSECIQ PEWMERWVRGLL* |
| Coding | >OphauG2|7764 ATGTCGCAAGCTCTTGGCAGCCAGAGACTCCTCACAGAAATAATCGACCACTTGTCAGAAACGGAGCCCGATGCC ACTTGGCTGGAATATCCCAAATCGACAAGCGACTACGCTGCCGGATTCAACGCTATTACATATCGCGCCCTGGCA AACGCTGTAAATGGCCTGGCTTGGCATCTCCATCGAAACGTGGAAAAGACGTCGGAATTCCAGACCATAGCTTAT ATCGGGCAAAATGACGCACGGTACGCCTTGATGCTCTACGCCTGTATCAAGGCTGGATTCAAGGTTTTCTTCACG TCGCCAAAGAACAGTGTGTCCACTCATCTTGGCTTGTTCTCTACTCTCCAATGCTCCATCTTGGTCACTACCAGG CCCACGCCGGCCATTGTCGAGGACATATCGTCCGCCCATTCGATGCAGGTTGTTTTCATTCCCAGCCTGGAAGAG TTACTCGAGAAGCACTATGAAACATTTCCGTGTAACAAGACATTTGCCGACGCGCGGAGTGAACCATTTCTTGTT CTACACACATCTGGCTCCACCTCTAGCCCCAAGGCCCTGGTATACACTCACGAGTTTGTCTCGCGGAACATTAGT GCCCTTCAACTCTCCACCCCAATGGAATTCTTTTCCGTCTACCAGTTATACTTGGGAAGCCGCTACATTTCTCTG TTTCCCCTTTTTCATATGGCTGGCTACTGGCTGGCCTGTGTTGCTACTCTTTTCAGTCGAGCAACTGTCATTCTT CCCTCTCCGAGCTCACCACCCACAGGCGACACTCTCTATGCCATGCTTCACCACACTACGGCGAACTGGGCCGCT GTGTCTCCAGTCACTGTAGACAGCATTGGACGTAACCCGGAAGCCCTACAATTTATTTCAGAGAATCTTGAGAGG CTCATTTTCGCCGGTGGCAATCCATCTGTTGCCATGGGAAACAAAGTCTCGTCCAAGATTAAGATTTGTAATCTA TATGGTTCCAGCGAATGTGGAGGGTGCGCGCACCTAATCCCCAATGATAATGCCGATGAGCACAGCGAGAGGCTC TGGAGCTATATCAGCATTCAGTCTCAGACCAATCCCGTCTTTGAAGAGCATACCCCTGGCTTATATGAGCTGGTT ATCAAGCGCGATCCTCTTTGCGAGGCATATCAACCCGTTTTTGAGCAGCGGCCCGAACTCCAAGAATTCAGAACA AGCGACCTATTTGCTCCTCATCCCAAGGTACCGGGATTTTGGCAGCACAGGGGAAGAATCGATGACACGATTGTA TTTCTCAGCGGCGAGAAGACTAATCCACTCAGTTTTGAATCTTTTGTGCTAGACCATCCAGACGTTTCGGGGGCA CTCGTCTTTGGCACCAATCGCATGGAGGCCGGCATCTTGATTGAACTCGCAGATACCGAGCAAAGTCAACTATTG CTACATGATAAAAAGGAAGCAATCGACAATCTTTGGCCTAGAATAGACATGGCAAATTCTTCCGCCCCGGTCTAT GCGCGCATCGCCGAGTCTCACGTCTGCTTTGTGTCTCCAAAGAAGCCAATGTTGAGAAGTGGAAAGGGCACAATA AGACGCCAAGATACGATTCGTTTATATGCCGAGGAAATTGAAGAAATATACAAAGAGTCAGAGCTGCTGAATGGC CAATCTGAATCAAGATCCATTGACATCAATAACATCGACGAAATCGCTCAAGCCATACGTTCTGCCTTTGCCATC GTCACGAAGCGCGATATTCCGGATGATGCCGACTTTTTCAGTATTGGGATGGATTCCGTACAAGTCATCCGGCTG GTTCGACAGCTACGCAGAGTGACAGGGCTCGCAGACATTACGCCCGCACTAGTCTACAAGAATCCGTCTATTTCT ACACTGAGTTTGGAGATTGCAAAAAGTGCCTCCAGTAATGCCAAGGAAAATTCATCCGTTACGGGAGTTGAAAGA TTACAAGTATTAGAGCAGACTATACAAGAATATAAAGGCAAAATCGCCGAGTTGATGCAGGCAACGAAAAACAGC CATGCGCAAAGCTCGCAGCAGCAGTCCACAATTCTCGTCACTGGTACAACTGGCTACATAGGATCCTATATCCTA AATTCGCTCTTGGCTCACCCGTCGTCTCCAAAAATCATCTGCCTTAACCGCTCGGCAGATTCCGTGCATGTTCAG GCATCTCGAAACAAGCTGCGAGACGAGTCCCTGGCCACGCACTTTCCTGCCGACCGGGTCAAGTTTTTGTCTTCC ACGGACACGTCCAACGCTCAATTAGGTCTCTCTGATCTTGAGTATCAGCACTTGCTGCGGCAAGTGACGTTGGTT ATTCACAATGCCTGGCCGGTCGATTTTAATCTCCCTCTCTCCGCCTTTAGGGCTTCCCTTGACGGCCTTGTCGGC ATTATTGAGCTTTGCAAAACTGGAAATTACTCACCCTCCTTGATCTTTGTGTCATCAATAAGCGTAGCTATGAAT TTACAGGCTCAGTATATATCCGAAGCAATTATTGATAATCTAGAAGCGCCAACTCCGGGTTATGGCGAGAGCAAG TTTGTCGCTGAACACATGCTATTCGAAGCCTCTCGAAAGCTCAACTTCAAAGCGAGTGTCGTGCGCGTTGGCCAG GTCTCAGGCGCTGCATATTCCCCAGGGCGATGGAATCGCAGGGACTGGCTGCCTCGCATGGTGCTGAGCTCTAGA TATATCGGAGCGATTCCCAAGCACCTCGGAGTTCTCAACAAGATTGAATGGATTCCCATCGATGTTTTATCAAAA TTTGTGATCGAAATTTCCACAAAACTAGGCTTCGATTCGTCATTCGAGGTTTATCACGCAATAAATCCGCATGTC ACAACTTGGCAAAAACTGTTGCCCACCGTCATCCAAGCTCTCGATACGGAGAGCCCGGCTACTGAAAAGTCTACA ATGGACTGTATTTCGCCTACAGAATGGGTGGAGAGACTACGCCAGAGTTCGGTTGACTTTGCATCCGACAAGGAT GATGAACAAATTGATACTCGCAACCCTGCACTAAAGCTCCTCGATTTTTTTGACGAGACATTCCAGATAGAAGCT TCTGAAAAAGTTGATTGGAGTACAGAAGTTTCCGTCAAGATGAGTGAGACCCTACGCAGGTCAGAGTGTATACAG CCAGAGTGGATGGAGCGCTGGGTTCGGGGATTATTGTAA |
| Transcript | >OphauG2|7764 ATGTCGCAAGCTCTTGGCAGCCAGAGACTCCTCACAGAAATAATCGACCACTTGTCAGAAACGGAGCCCGATGCC ACTTGGCTGGAATATCCCAAATCGACAAGCGACTACGCTGCCGGATTCAACGCTATTACATATCGCGCCCTGGCA AACGCTGTAAATGGCCTGGCTTGGCATCTCCATCGAAACGTGGAAAAGACGTCGGAATTCCAGACCATAGCTTAT ATCGGGCAAAATGACGCACGGTACGCCTTGATGCTCTACGCCTGTATCAAGGCTGGATTCAAGGTTTTCTTCACG TCGCCAAAGAACAGTGTGTCCACTCATCTTGGCTTGTTCTCTACTCTCCAATGCTCCATCTTGGTCACTACCAGG CCCACGCCGGCCATTGTCGAGGACATATCGTCCGCCCATTCGATGCAGGTTGTTTTCATTCCCAGCCTGGAAGAG TTACTCGAGAAGCACTATGAAACATTTCCGTGTAACAAGACATTTGCCGACGCGCGGAGTGAACCATTTCTTGTT CTACACACATCTGGCTCCACCTCTAGCCCCAAGGCCCTGGTATACACTCACGAGTTTGTCTCGCGGAACATTAGT GCCCTTCAACTCTCCACCCCAATGGAATTCTTTTCCGTCTACCAGTTATACTTGGGAAGCCGCTACATTTCTCTG TTTCCCCTTTTTCATATGGCTGGCTACTGGCTGGCCTGTGTTGCTACTCTTTTCAGTCGAGCAACTGTCATTCTT CCCTCTCCGAGCTCACCACCCACAGGCGACACTCTCTATGCCATGCTTCACCACACTACGGCGAACTGGGCCGCT GTGTCTCCAGTCACTGTAGACAGCATTGGACGTAACCCGGAAGCCCTACAATTTATTTCAGAGAATCTTGAGAGG CTCATTTTCGCCGGTGGCAATCCATCTGTTGCCATGGGAAACAAAGTCTCGTCCAAGATTAAGATTTGTAATCTA TATGGTTCCAGCGAATGTGGAGGGTGCGCGCACCTAATCCCCAATGATAATGCCGATGAGCACAGCGAGAGGCTC TGGAGCTATATCAGCATTCAGTCTCAGACCAATCCCGTCTTTGAAGAGCATACCCCTGGCTTATATGAGCTGGTT ATCAAGCGCGATCCTCTTTGCGAGGCATATCAACCCGTTTTTGAGCAGCGGCCCGAACTCCAAGAATTCAGAACA AGCGACCTATTTGCTCCTCATCCCAAGGTACCGGGATTTTGGCAGCACAGGGGAAGAATCGATGACACGATTGTA TTTCTCAGCGGCGAGAAGACTAATCCACTCAGTTTTGAATCTTTTGTGCTAGACCATCCAGACGTTTCGGGGGCA CTCGTCTTTGGCACCAATCGCATGGAGGCCGGCATCTTGATTGAACTCGCAGATACCGAGCAAAGTCAACTATTG CTACATGATAAAAAGGAAGCAATCGACAATCTTTGGCCTAGAATAGACATGGCAAATTCTTCCGCCCCGGTCTAT GCGCGCATCGCCGAGTCTCACGTCTGCTTTGTGTCTCCAAAGAAGCCAATGTTGAGAAGTGGAAAGGGCACAATA AGACGCCAAGATACGATTCGTTTATATGCCGAGGAAATTGAAGAAATATACAAAGAGTCAGAGCTGCTGAATGGC CAATCTGAATCAAGATCCATTGACATCAATAACATCGACGAAATCGCTCAAGCCATACGTTCTGCCTTTGCCATC GTCACGAAGCGCGATATTCCGGATGATGCCGACTTTTTCAGTATTGGGATGGATTCCGTACAAGTCATCCGGCTG GTTCGACAGCTACGCAGAGTGACAGGGCTCGCAGACATTACGCCCGCACTAGTCTACAAGAATCCGTCTATTTCT ACACTGAGTTTGGAGATTGCAAAAAGTGCCTCCAGTAATGCCAAGGAAAATTCATCCGTTACGGGAGTTGAAAGA TTACAAGTATTAGAGCAGACTATACAAGAATATAAAGGCAAAATCGCCGAGTTGATGCAGGCAACGAAAAACAGC CATGCGCAAAGCTCGCAGCAGCAGTCCACAATTCTCGTCACTGGTACAACTGGCTACATAGGATCCTATATCCTA AATTCGCTCTTGGCTCACCCGTCGTCTCCAAAAATCATCTGCCTTAACCGCTCGGCAGATTCCGTGCATGTTCAG GCATCTCGAAACAAGCTGCGAGACGAGTCCCTGGCCACGCACTTTCCTGCCGACCGGGTCAAGTTTTTGTCTTCC ACGGACACGTCCAACGCTCAATTAGGTCTCTCTGATCTTGAGTATCAGCACTTGCTGCGGCAAGTGACGTTGGTT ATTCACAATGCCTGGCCGGTCGATTTTAATCTCCCTCTCTCCGCCTTTAGGGCTTCCCTTGACGGCCTTGTCGGC ATTATTGAGCTTTGCAAAACTGGAAATTACTCACCCTCCTTGATCTTTGTGTCATCAATAAGCGTAGCTATGAAT TTACAGGCTCAGTATATATCCGAAGCAATTATTGATAATCTAGAAGCGCCAACTCCGGGTTATGGCGAGAGCAAG TTTGTCGCTGAACACATGCTATTCGAAGCCTCTCGAAAGCTCAACTTCAAAGCGAGTGTCGTGCGCGTTGGCCAG GTCTCAGGCGCTGCATATTCCCCAGGGCGATGGAATCGCAGGGACTGGCTGCCTCGCATGGTGCTGAGCTCTAGA TATATCGGAGCGATTCCCAAGCACCTCGGAGTTCTCAACAAGATTGAATGGATTCCCATCGATGTTTTATCAAAA TTTGTGATCGAAATTTCCACAAAACTAGGCTTCGATTCGTCATTCGAGGTTTATCACGCAATAAATCCGCATGTC ACAACTTGGCAAAAACTGTTGCCCACCGTCATCCAAGCTCTCGATACGGAGAGCCCGGCTACTGAAAAGTCTACA ATGGACTGTATTTCGCCTACAGAATGGGTGGAGAGACTACGCCAGAGTTCGGTTGACTTTGCATCCGACAAGGAT GATGAACAAATTGATACTCGCAACCCTGCACTAAAGCTCCTCGATTTTTTTGACGAGACATTCCAGATAGAAGCT TCTGAAAAAGTTGATTGGAGTACAGAAGTTTCCGTCAAGATGAGTGAGACCCTACGCAGGTCAGAGTGTATACAG CCAGAGTGGATGGAGCGCTGGGTTCGGGGATTATTGTAA |
| Gene | >OphauG2|7764 ATGTCGCAAGCTCTTGGCAGCCAGAGACTCCTCACAGAAATAATCGACCACTTGTCAGAAACGGAGCCCGATGCC ACTTGGCTGGAATATCCCAAATCGACAAGCGACTACGCTGCCGGATTCAACGCTATTACATATCGCGCCCTGGCA AACGCTGTAAATGGCCTGGCTTGGCATCTCCATCGAAACGTGGAAAAGACGTCGGAATTCCAGACCATAGCTTAT ATCGGGCAAAATGACGCACGGTACGCCTTGATGCTCTACGCCTGTATCAAGGCTGGATTCAAGGTGAACCCATGC TCCAGCTCACGGCTTTTATAGTCTGTTGCTGATAAGAATCATAATCAGGTTTTCTTCACGTCGCCAAAGAACAGT GTGTCCACTCATCTTGGCTTGTTCTCTACTCTCCAATGCTCCATCTTGGTCACTACCAGGCCCACGCCGGCCATT GTCGAGGACATATCGTCCGCCCATTCGATGCAGGTTGTTTTCATTCCCAGCCTGGAAGAGTTACTCGAGAAGCAC TATGAAACATTTCCGTGTAACAAGACATTTGCCGACGCGCGGAGTGAACCATTTCTTGTTCTACACACATCTGGC TCCACCTGTAAGCTCCAGGACTACAAAAGCCATTGAATATTGAAGCTCTGACTCATTTTAATGATTGTTTTAGCT AGCCCCAAGGCCCTGGTATACACTCACGAGTTTGTCTCGCGGAACATTAGTGCCCTTCAACTCTCCACCCCAATG GAATTCTTTTCCGTCTACCAGTTATACTTGGGAAGCCGCTACATTTCTCTGTTTCCCCTTTTTCATGTAAGTCTT GTTGGCGCTTCATAGTCTGACCCGCGGCGATTAACGTTGGCGATTGTAGATGGCTGGCTACTGGCTGGCCTGTGT TGCTACTCTTTTCAGTCGAGCAACTGTCATTCTTCCCTCTCCGAGCTCACCACCCACAGGCGACACTCTCTATGC CATGCTTCACCACACTACGGCGAACTGGGCCGCTGTGTCTCCAGTCACTGTAGACAGCATTGGACGTAACCCGGA AGCCCTACAATTTATTTCAGAGAATCTTGAGAGGCTCATTTTCGCCGGTGGCAATCCATCTGTTGCCATGGGAAA CAAAGTCTCGTCCAAGATTAAGATTTGTAATCTATATGGTTCCAGCGAATGTGGAGGGTGCGCGCACCTAATCCC CAATGATAATGCCGATGAGCACAGCGAGAGGCTCTGGAGCTATATCAGCATTCAGTCTCAGACCAATCCCGTCTT TGAAGAGCATACCCCTGGCTTATATGAGCTGGTTATCAAGCGCGATCCTCTTTGCGAGGCATATCAACCCGTTTT TGAGCAGCGGCCCGAACTCCAAGAATTCAGAACAAGCGACCTATTTGCTCCTCATCCCAAGGTACCGGGATTTTG GCAGCACAGGGGAAGAATCGATGACACGATTGTATTTCTCAGCGGCGAGAAGACTAATCCACTCAGTTTTGAATC TTTTGTGCTAGACCATCCAGACGTTTCGGGGGCACTCGTCTTTGGCACCAATCGCATGGAGGCCGGCATCTTGAT TGAACTCGCAGATACCGAGCAAAGTCAACTATTGCTACATGATAAAAAGGAAGCAATCGACAATCTTTGGCCTAG AATAGACATGGCAAATTCTTCCGCCCCGGTCTATGCGCGCATCGCCGAGTCTCACGTCTGCTTTGTGTCTCCAAA GAAGCCAATGTTGAGAAGTGGAAAGGGCACAATAAGACGCCAAGATACGATTCGTTTATATGCCGAGGAAATTGA AGAAATATACAAAGAGTCAGAGCTGCTGAATGGCCAATCTGAATCAAGATCCATTGACATCAATAACATCGACGA AATCGCTCAAGCCATACGTTCTGCCTTTGCCATCGTCACGAAGCGCGATATTCCGGATGATGCCGACTTTTTCAG TATTGGGATGGATTCCGTACAAGTCATCCGGCTGGTTCGACAGCTACGCAGAGTGACAGGGCTCGCAGACATTAC GCCCGCACTAGTCTACAAGAATCCGTCTATTTCTACACTGAGTTTGGAGATTGCAAAAAGTGCCTCCAGTAATGC CAAGGAAAATTCATCCGTTACGGGAGTTGAAAGATTACAAGTATTAGAGCAGACTATACAAGAATATAAAGGCAA AATCGCCGAGTTGATGCAGGCAACGAAAAACAGCCATGCGCAAAGCTCGCAGCAGCAGTCCACAATTCTCGTCAC TGGTACAACTGGCTACATAGGATCCTATATCCTAAATTCGCTCTTGGCTCACCCGTCGTCTCCAAAAATCATCTG CCTTAACCGCTCGGCAGATTCCGTGCATGTTCAGGCATCTCGAAACAAGCTGCGAGACGAGTCCCTGGCCACGCA CTTTCCTGCCGACCGGGTCAAGTTTTTGTCTTCCACGGACACGTCCAACGCTCAATTAGGTCTCTCTGATCTTGA GTATCAGCACTTGCTGCGGCAAGTGACGTTGGTTATTCACAATGCCTGGCCGGTCGATTTTAATCTCCCTCTCTC CGCCTTTAGGGCTTCCCTTGACGGCCTTGTCGGCATTATTGAGCTTTGCAAAACTGGAAATTACTCACCCTCCTT GATCTTTGTGTCATCAATAAGCGTAGCTATGAATTTACAGGCTCAGTATATATCCGAAGCAATTATTGATAATCT AGAAGCGCCAACTCCGGGTTATGGCGAGAGCAAGTTTGTCGCTGAACACATGCTATTCGAAGCCTCTCGAAAGCT CAACTTCAAAGCGAGTGTCGTGCGCGTTGGCCAGGTCTCAGGCGCTGCATATTCCCCAGGGCGATGGAATCGCAG GGACTGGCTGCCTCGCATGGTGCTGAGCTCTAGATATATCGGAGCGATTCCCAAGCACCTCGGAGTTCTCAACAA GATTGAATGGATTCCCATCGATGTTTTATCAAAATTTGTGATCGAAATTTCCACAAAACTAGGCTTCGATTCGTC ATTCGAGGTTTATCACGCAATAAATCCGCATGTCACAACTTGGCAAAAACTGTTGCCCACCGTCATCCAAGCTCT CGATACGGAGAGCCCGGCTACTGAAAAGTCTACAATGGACTGTATTTCGCCTACAGAATGGGTGGAGAGACTACG CCAGAGTTCGGTTGACTTTGCATCCGACAAGGATGATGAACAAATTGATACTCGCAACCCTGCACTAAAGCTCCT CGATTTTTTTGACGAGACATTCCAGATAGAAGCTTCTGAAAAAGTTGATTGGAGTACAGAAGTTTCCGTCAAGAT GAGTGAGACCCTACGCAGGTCAGAGTGTATACAGCCAGAGTGGATGGAGCGCTGGGTTCGGGGATTATTGTAA |