© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | OphauG2|7010 |
| Gene name | |
| Location | Contig_774:6248..8225 |
| Strand | + |
| Gene length (bp) | 1977 |
| Transcript length (bp) | 1977 |
| Coding sequence length (bp) | 1977 |
| Protein length (aa) | 659 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF03074 | GCS | Glutamate-cysteine ligase | 3.4E-176 | 198 | 587 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q8X0X0|GSH1_NEUCR | Glutamate--cysteine ligase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=gcs-1 PE=3 SV=1 | 2 | 619 | 0.0E+00 |
| sp|Q09768|GSH1_SCHPO | Glutamate--cysteine ligase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gcs1 PE=3 SV=1 | 11 | 589 | 0.0E+00 |
| sp|P97494|GSH1_MOUSE | Glutamate--cysteine ligase catalytic subunit OS=Mus musculus GN=Gclc PE=1 SV=4 | 47 | 606 | 5.0E-179 |
| sp|P19468|GSH1_RAT | Glutamate--cysteine ligase catalytic subunit OS=Rattus norvegicus GN=Gclc PE=1 SV=2 | 47 | 606 | 4.0E-178 |
| sp|P48506|GSH1_HUMAN | Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens GN=GCLC PE=1 SV=2 | 9 | 606 | 1.0E-177 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q8X0X0|GSH1_NEUCR | Glutamate--cysteine ligase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=gcs-1 PE=3 SV=1 | 2 | 619 | 0.0E+00 |
| sp|Q09768|GSH1_SCHPO | Glutamate--cysteine ligase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gcs1 PE=3 SV=1 | 11 | 589 | 0.0E+00 |
| sp|P97494|GSH1_MOUSE | Glutamate--cysteine ligase catalytic subunit OS=Mus musculus GN=Gclc PE=1 SV=4 | 47 | 606 | 5.0E-179 |
| sp|P19468|GSH1_RAT | Glutamate--cysteine ligase catalytic subunit OS=Rattus norvegicus GN=Gclc PE=1 SV=2 | 47 | 606 | 4.0E-178 |
| sp|P48506|GSH1_HUMAN | Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens GN=GCLC PE=1 SV=2 | 9 | 606 | 1.0E-177 |
| sp|Q54PC2|GSH1_DICDI | Glutamate--cysteine ligase OS=Dictyostelium discoideum GN=gcsA PE=2 SV=1 | 11 | 590 | 3.0E-164 |
| sp|Q20117|GSH1_CAEEL | Glutamate--cysteine ligase OS=Caenorhabditis elegans GN=gcs-1 PE=1 SV=2 | 6 | 645 | 4.0E-160 |
| sp|Q9NFN6|GSH1_ONCVO | Glutamate--cysteine ligase OS=Onchocerca volvulus GN=gcs-1 PE=2 SV=2 | 2 | 591 | 1.0E-153 |
| sp|Q9W3K5|GSH1_DROME | Glutamate--cysteine ligase OS=Drosophila melanogaster GN=Gclc PE=2 SV=1 | 20 | 454 | 4.0E-126 |
| sp|Q9HF78|GSH1_CANAX | Glutamate--cysteine ligase OS=Candida albicans GN=GCS1 PE=3 SV=1 | 9 | 452 | 2.0E-118 |
| sp|P32477|GSH1_YEAST | Glutamate--cysteine ligase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GSH1 PE=1 SV=1 | 48 | 586 | 3.0E-117 |
| sp|Q9W3K5|GSH1_DROME | Glutamate--cysteine ligase OS=Drosophila melanogaster GN=Gclc PE=2 SV=1 | 498 | 591 | 3.0E-17 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0004357 | glutamate-cysteine ligase activity | Yes |
| GO:0006750 | glutathione biosynthetic process | Yes |
| GO:0006790 | sulfur compound metabolic process | No |
| GO:0044272 | sulfur compound biosynthetic process | No |
| GO:0016881 | acid-amino acid ligase activity | No |
| GO:1901566 | organonitrogen compound biosynthetic process | No |
| GO:0008150 | biological_process | No |
| GO:0008152 | metabolic process | No |
| GO:0009058 | biosynthetic process | No |
| GO:1901576 | organic substance biosynthetic process | No |
| GO:0016879 | ligase activity, forming carbon-nitrogen bonds | No |
| GO:0043603 | cellular amide metabolic process | No |
| GO:0016874 | ligase activity | No |
| GO:0006749 | glutathione metabolic process | No |
| GO:0009987 | cellular process | No |
| GO:0019184 | nonribosomal peptide biosynthetic process | No |
| GO:0006807 | nitrogen compound metabolic process | No |
| GO:0006518 | peptide metabolic process | No |
| GO:0071704 | organic substance metabolic process | No |
| GO:0043604 | amide biosynthetic process | No |
| GO:0044271 | cellular nitrogen compound biosynthetic process | No |
| GO:0044249 | cellular biosynthetic process | No |
| GO:0003674 | molecular_function | No |
| GO:0006575 | cellular modified amino acid metabolic process | No |
| GO:0042398 | cellular modified amino acid biosynthetic process | No |
| GO:1901564 | organonitrogen compound metabolic process | No |
| GO:0044237 | cellular metabolic process | No |
| GO:0003824 | catalytic activity | No |
| GO:0043043 | peptide biosynthetic process | No |
| GO:0034641 | cellular nitrogen compound metabolic process | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 25 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >OphauG2|7010 MYSKDDTKVLVSLRQAEILTALDADKDLNRVSEHSNGTPDKSSSLPVFHPEFGRFMLEATPGKPWGIGFKELLDV EPDMKLRRKIAKEHMLSNEYPITLTTFPRLGCQGQFTHPSYPPSGPKLRSQFVPDEIANPHIRFPTLAANIRHRR GRKVQVNVPVFHDEKTSSPWKDPTVNYDLHNWPEDDDVRNGAAPDDHIHMDAMAFGMGSCCLQITFQAKNINEGR QLYDQLSPLGPIMLALTAATPIYKGFLAKTDVRWNQISRAVDCRTPEELGEKPLKNDRWRIPKSRYASNSTYIST DSRLRREYLDPDLVIDEEIKASLVKGGMDDLLATHFAHLFIRDPIVVFEEDLLELDLGKTDHFENIQSTNWQHMR FKPPPAENNIGWRVEFRSMEIQITDFENAAFSVFMVLITRAILSFDLNFYIPIKRVDENMERAHALDAVLNQKFF FRKNPFPPRASRANTAFGGGEESRPGSAMPSRPGSPPPGPVEDEYCEMSIDEIVNGSAEGDFPGLIPIVESYLDS VNVDVETRCRLSTYLDLIGRRACGRLDTAARWIRNFVQSHPRYGRDSVVDDEIVHDLVGAVIAVGEREARGQGFA RLGINGLHRLLGPFRGGCGQPETDQDSNGAVANEAVEPGSPSRKRKSEWIDGEAVRVE* |
| Coding | >OphauG2|7010 ATGTACTCCAAGGACGACACCAAAGTTCTTGTGTCTCTGCGCCAGGCTGAGATTCTGACGGCTCTAGACGCGGAC AAGGACTTGAATCGTGTTTCGGAACACAGCAACGGAACACCTGACAAGTCGAGTTCGCTGCCAGTATTTCACCCC GAGTTTGGCCGCTTCATGCTCGAGGCGACCCCGGGCAAACCATGGGGCATTGGCTTCAAGGAGCTTCTTGACGTT GAGCCTGATATGAAGCTCCGGCGTAAGATTGCCAAGGAGCACATGTTGTCCAATGAGTATCCCATTACCCTGACG ACATTTCCTCGCTTGGGGTGCCAAGGACAATTCACCCACCCCTCCTATCCGCCATCTGGGCCCAAACTGCGCTCT CAGTTTGTGCCTGACGAAATTGCCAACCCCCATATTCGCTTCCCTACATTGGCTGCCAATATACGCCATCGGCGC GGCCGCAAGGTTCAAGTCAATGTGCCCGTCTTTCACGATGAAAAGACATCGAGTCCGTGGAAGGATCCAACAGTC AACTACGATTTGCACAACTGGCCCGAGGATGACGATGTGCGCAACGGCGCGGCCCCAGACGACCATATACACATG GACGCCATGGCTTTTGGCATGGGAAGCTGTTGCCTGCAGATTACTTTTCAGGCCAAGAATATAAACGAGGGAAGA CAGCTGTACGATCAGCTGAGCCCTCTTGGACCTATTATGCTGGCTCTCACGGCGGCCACACCCATCTACAAGGGC TTCCTGGCCAAGACGGATGTGCGGTGGAACCAAATTAGCCGCGCTGTAGACTGCAGAACGCCGGAGGAACTAGGG GAAAAGCCTCTCAAAAACGATCGATGGCGCATCCCCAAGTCGAGGTATGCCTCAAACTCGACGTACATCTCTACC GACTCGAGACTGCGACGGGAATACCTCGACCCAGACCTGGTGATTGACGAGGAAATCAAGGCCAGTCTGGTAAAA GGCGGCATGGACGACCTGCTGGCGACTCACTTTGCCCACCTCTTCATCCGTGACCCCATTGTTGTCTTTGAGGAG GACTTGTTGGAGCTAGACTTGGGCAAAACGGATCATTTTGAGAATATACAGTCAACCAATTGGCAGCACATGCGC TTCAAACCGCCGCCGGCCGAGAACAATATTGGCTGGCGAGTCGAGTTCCGGTCAATGGAGATTCAAATCACAGAC TTTGAGAATGCGGCCTTTTCAGTCTTCATGGTGCTCATTACCCGGGCCATTTTGTCCTTTGATCTCAATTTCTAC ATACCCATCAAGAGGGTGGACGAGAATATGGAAAGGGCACACGCACTCGATGCTGTACTCAATCAAAAGTTTTTC TTTCGCAAGAATCCCTTCCCGCCTCGAGCGTCGCGTGCCAATACGGCATTTGGGGGCGGAGAAGAGTCGCGGCCC GGCTCTGCCATGCCTAGCAGGCCTGGATCGCCGCCGCCGGGCCCCGTAGAGGACGAGTACTGCGAAATGTCGATT GACGAGATTGTAAATGGCAGCGCCGAGGGCGATTTCCCCGGGCTCATTCCCATTGTGGAGAGCTACCTGGACAGC GTCAATGTCGACGTGGAGACGCGCTGCCGCCTATCGACATATCTCGATTTGATTGGGCGCCGTGCTTGTGGCCGG CTGGATACGGCGGCGCGGTGGATCCGCAACTTTGTACAGTCGCACCCACGGTACGGGCGCGACAGCGTCGTCGAT GACGAGATTGTGCACGACCTAGTGGGTGCCGTTATTGCCGTTGGCGAGCGCGAGGCCCGGGGCCAGGGGTTTGCC CGTCTTGGAATTAACGGGCTTCATCGGTTGCTGGGACCATTTCGCGGCGGATGTGGCCAGCCTGAGACAGACCAG GACAGCAACGGCGCCGTGGCAAACGAGGCAGTCGAGCCCGGGTCGCCGTCGCGGAAACGCAAAAGCGAATGGATC GACGGCGAGGCGGTCAGGGTGGAGTGA |
| Transcript | >OphauG2|7010 ATGTACTCCAAGGACGACACCAAAGTTCTTGTGTCTCTGCGCCAGGCTGAGATTCTGACGGCTCTAGACGCGGAC AAGGACTTGAATCGTGTTTCGGAACACAGCAACGGAACACCTGACAAGTCGAGTTCGCTGCCAGTATTTCACCCC GAGTTTGGCCGCTTCATGCTCGAGGCGACCCCGGGCAAACCATGGGGCATTGGCTTCAAGGAGCTTCTTGACGTT GAGCCTGATATGAAGCTCCGGCGTAAGATTGCCAAGGAGCACATGTTGTCCAATGAGTATCCCATTACCCTGACG ACATTTCCTCGCTTGGGGTGCCAAGGACAATTCACCCACCCCTCCTATCCGCCATCTGGGCCCAAACTGCGCTCT CAGTTTGTGCCTGACGAAATTGCCAACCCCCATATTCGCTTCCCTACATTGGCTGCCAATATACGCCATCGGCGC GGCCGCAAGGTTCAAGTCAATGTGCCCGTCTTTCACGATGAAAAGACATCGAGTCCGTGGAAGGATCCAACAGTC AACTACGATTTGCACAACTGGCCCGAGGATGACGATGTGCGCAACGGCGCGGCCCCAGACGACCATATACACATG GACGCCATGGCTTTTGGCATGGGAAGCTGTTGCCTGCAGATTACTTTTCAGGCCAAGAATATAAACGAGGGAAGA CAGCTGTACGATCAGCTGAGCCCTCTTGGACCTATTATGCTGGCTCTCACGGCGGCCACACCCATCTACAAGGGC TTCCTGGCCAAGACGGATGTGCGGTGGAACCAAATTAGCCGCGCTGTAGACTGCAGAACGCCGGAGGAACTAGGG GAAAAGCCTCTCAAAAACGATCGATGGCGCATCCCCAAGTCGAGGTATGCCTCAAACTCGACGTACATCTCTACC GACTCGAGACTGCGACGGGAATACCTCGACCCAGACCTGGTGATTGACGAGGAAATCAAGGCCAGTCTGGTAAAA GGCGGCATGGACGACCTGCTGGCGACTCACTTTGCCCACCTCTTCATCCGTGACCCCATTGTTGTCTTTGAGGAG GACTTGTTGGAGCTAGACTTGGGCAAAACGGATCATTTTGAGAATATACAGTCAACCAATTGGCAGCACATGCGC TTCAAACCGCCGCCGGCCGAGAACAATATTGGCTGGCGAGTCGAGTTCCGGTCAATGGAGATTCAAATCACAGAC TTTGAGAATGCGGCCTTTTCAGTCTTCATGGTGCTCATTACCCGGGCCATTTTGTCCTTTGATCTCAATTTCTAC ATACCCATCAAGAGGGTGGACGAGAATATGGAAAGGGCACACGCACTCGATGCTGTACTCAATCAAAAGTTTTTC TTTCGCAAGAATCCCTTCCCGCCTCGAGCGTCGCGTGCCAATACGGCATTTGGGGGCGGAGAAGAGTCGCGGCCC GGCTCTGCCATGCCTAGCAGGCCTGGATCGCCGCCGCCGGGCCCCGTAGAGGACGAGTACTGCGAAATGTCGATT GACGAGATTGTAAATGGCAGCGCCGAGGGCGATTTCCCCGGGCTCATTCCCATTGTGGAGAGCTACCTGGACAGC GTCAATGTCGACGTGGAGACGCGCTGCCGCCTATCGACATATCTCGATTTGATTGGGCGCCGTGCTTGTGGCCGG CTGGATACGGCGGCGCGGTGGATCCGCAACTTTGTACAGTCGCACCCACGGTACGGGCGCGACAGCGTCGTCGAT GACGAGATTGTGCACGACCTAGTGGGTGCCGTTATTGCCGTTGGCGAGCGCGAGGCCCGGGGCCAGGGGTTTGCC CGTCTTGGAATTAACGGGCTTCATCGGTTGCTGGGACCATTTCGCGGCGGATGTGGCCAGCCTGAGACAGACCAG GACAGCAACGGCGCCGTGGCAAACGAGGCAGTCGAGCCCGGGTCGCCGTCGCGGAAACGCAAAAGCGAATGGATC GACGGCGAGGCGGTCAGGGTGGAGTGA |
| Gene | >OphauG2|7010 ATGTACTCCAAGGACGACACCAAAGTTCTTGTGTCTCTGCGCCAGGCTGAGATTCTGACGGCTCTAGACGCGGAC AAGGACTTGAATCGTGTTTCGGAACACAGCAACGGAACACCTGACAAGTCGAGTTCGCTGCCAGTATTTCACCCC GAGTTTGGCCGCTTCATGCTCGAGGCGACCCCGGGCAAACCATGGGGCATTGGCTTCAAGGAGCTTCTTGACGTT GAGCCTGATATGAAGCTCCGGCGTAAGATTGCCAAGGAGCACATGTTGTCCAATGAGTATCCCATTACCCTGACG ACATTTCCTCGCTTGGGGTGCCAAGGACAATTCACCCACCCCTCCTATCCGCCATCTGGGCCCAAACTGCGCTCT CAGTTTGTGCCTGACGAAATTGCCAACCCCCATATTCGCTTCCCTACATTGGCTGCCAATATACGCCATCGGCGC GGCCGCAAGGTTCAAGTCAATGTGCCCGTCTTTCACGATGAAAAGACATCGAGTCCGTGGAAGGATCCAACAGTC AACTACGATTTGCACAACTGGCCCGAGGATGACGATGTGCGCAACGGCGCGGCCCCAGACGACCATATACACATG GACGCCATGGCTTTTGGCATGGGAAGCTGTTGCCTGCAGATTACTTTTCAGGCCAAGAATATAAACGAGGGAAGA CAGCTGTACGATCAGCTGAGCCCTCTTGGACCTATTATGCTGGCTCTCACGGCGGCCACACCCATCTACAAGGGC TTCCTGGCCAAGACGGATGTGCGGTGGAACCAAATTAGCCGCGCTGTAGACTGCAGAACGCCGGAGGAACTAGGG GAAAAGCCTCTCAAAAACGATCGATGGCGCATCCCCAAGTCGAGGTATGCCTCAAACTCGACGTACATCTCTACC GACTCGAGACTGCGACGGGAATACCTCGACCCAGACCTGGTGATTGACGAGGAAATCAAGGCCAGTCTGGTAAAA GGCGGCATGGACGACCTGCTGGCGACTCACTTTGCCCACCTCTTCATCCGTGACCCCATTGTTGTCTTTGAGGAG GACTTGTTGGAGCTAGACTTGGGCAAAACGGATCATTTTGAGAATATACAGTCAACCAATTGGCAGCACATGCGC TTCAAACCGCCGCCGGCCGAGAACAATATTGGCTGGCGAGTCGAGTTCCGGTCAATGGAGATTCAAATCACAGAC TTTGAGAATGCGGCCTTTTCAGTCTTCATGGTGCTCATTACCCGGGCCATTTTGTCCTTTGATCTCAATTTCTAC ATACCCATCAAGAGGGTGGACGAGAATATGGAAAGGGCACACGCACTCGATGCTGTACTCAATCAAAAGTTTTTC TTTCGCAAGAATCCCTTCCCGCCTCGAGCGTCGCGTGCCAATACGGCATTTGGGGGCGGAGAAGAGTCGCGGCCC GGCTCTGCCATGCCTAGCAGGCCTGGATCGCCGCCGCCGGGCCCCGTAGAGGACGAGTACTGCGAAATGTCGATT GACGAGATTGTAAATGGCAGCGCCGAGGGCGATTTCCCCGGGCTCATTCCCATTGTGGAGAGCTACCTGGACAGC GTCAATGTCGACGTGGAGACGCGCTGCCGCCTATCGACATATCTCGATTTGATTGGGCGCCGTGCTTGTGGCCGG CTGGATACGGCGGCGCGGTGGATCCGCAACTTTGTACAGTCGCACCCACGGTACGGGCGCGACAGCGTCGTCGAT GACGAGATTGTGCACGACCTAGTGGGTGCCGTTATTGCCGTTGGCGAGCGCGAGGCCCGGGGCCAGGGGTTTGCC CGTCTTGGAATTAACGGGCTTCATCGGTTGCTGGGACCATTTCGCGGCGGATGTGGCCAGCCTGAGACAGACCAG GACAGCAACGGCGCCGTGGCAAACGAGGCAGTCGAGCCCGGGTCGCCGTCGCGGAAACGCAAAAGCGAATGGATC GACGGCGAGGCGGTCAGGGTGGAGTGA |