Fungal Genomics

at Utrecht University

General Properties

Protein ID	OphauG2\|4172
Gene name
Location	Contig_34:2187..5985
Strand	-
Gene length (bp)	3798
Transcript length (bp)	3660
Coding sequence length (bp)	3660
Protein length (aa)	1220

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00168	C2	C2 domain	7.2E-15	486	585
PF00168	C2	C2 domain	8.8E-09	671	801

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9USG8\|MU190_SCHPO	Meiotically up-regulated gene 190 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug190 PE=1 SV=1	10	1219	0.0E+00
sp\|Q9UT00\|YKH3_SCHPO	Uncharacterized protein PYUK71.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAPYUK71.03c PE=1 SV=1	242	821	1.0E-17
sp\|Q12466\|TCB1_YEAST	Tricalbin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB1 PE=1 SV=1	242	659	1.0E-15
sp\|P48231\|TCB2_YEAST	Tricalbin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB2 PE=1 SV=1	242	830	8.0E-11
sp\|B6ETT4\|SYT2_ARATH	Synaptotagmin-2 OS=Arabidopsis thaliana GN=SYT2 PE=2 SV=1	244	590	8.0E-10

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9USG8\|MU190_SCHPO	Meiotically up-regulated gene 190 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug190 PE=1 SV=1	10	1219	0.0E+00
sp\|Q9UT00\|YKH3_SCHPO	Uncharacterized protein PYUK71.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAPYUK71.03c PE=1 SV=1	242	821	1.0E-17
sp\|Q12466\|TCB1_YEAST	Tricalbin-1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB1 PE=1 SV=1	242	659	1.0E-15
sp\|P48231\|TCB2_YEAST	Tricalbin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TCB2 PE=1 SV=1	242	830	8.0E-11
sp\|B6ETT4\|SYT2_ARATH	Synaptotagmin-2 OS=Arabidopsis thaliana GN=SYT2 PE=2 SV=1	244	590	8.0E-10
sp\|Q9BSJ8\|ESYT1_HUMAN	Extended synaptotagmin-1 OS=Homo sapiens GN=ESYT1 PE=1 SV=1	242	545	8.0E-10
sp\|Q3U7R1\|ESYT1_MOUSE	Extended synaptotagmin-1 OS=Mus musculus GN=Esyt1 PE=1 SV=2	179	545	4.0E-09
sp\|Q9Z1X1\|ESYT1_RAT	Extended synaptotagmin-1 OS=Rattus norvegicus GN=Esyt1 PE=1 SV=1	179	545	1.0E-08
sp\|Q7XA06\|SYT3_ARATH	Synaptotagmin-3 OS=Arabidopsis thaliana GN=SYT3 PE=2 SV=1	242	588	6.0E-08
sp\|Q9SKR2\|SYT1_ARATH	Synaptotagmin-1 OS=Arabidopsis thaliana GN=SYT1 PE=1 SV=2	191	590	1.0E-07
sp\|Q5DTI8\|ESYT3_MOUSE	Extended synaptotagmin-3 OS=Mus musculus GN=Esyt3 PE=2 SV=2	389	585	3.0E-07

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 49	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	175	192	17
2	196	213	17
3	368	390	22

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>OphauG2\|4172 MNVDEHMAPSGQHYSGSNRVPNIQEFMEQLDSEKRERDAAIDRDLNRNKRSKEAKDHRNSDAPKHKDTRTVRDPV TGKDVQIRDAQMDFCEAVDRPQLSIPNENLGKPTTVRVTSQQSGEEYRRAQDIAAPPDPIQEGATSDVPIRSEKT SVLFFKTPSVSYEPMFVSLERKANVLCIAISVAIVVVGKVFGGKLLGLVPLAGFVSAAVFLWIKDLIRQGRDTEW ASEQDRGETATVNLIPESVEWMNTAIGIFWGLINPEMFAAVADTLEDVMAASVPGVVENVRVADISQGNNPIRIL NMRALPDSHVQDIKQQIHEENEKKMDSDELAAVEQAGAFYNLEVSVAYHAKPSGQDIASKASNMGMQLVFYLGIR GLFGVPLPVWVELIGLVATARIRFQLTPDPPFLKTVTVTLMGIPKVQAGCTPMIERGVNILNLPLISNFVNWAIG AAASMYVAPKSLTLDMSKMLQGDDIKKETIGLGVMFIRIHKATGLSKQDQRGSKGGGSDPYITVSWSKFSKPQFC TRVIQDDLNPVFEETCGLIVTSDLIKADEQLSMELWDSDRSSADDVVGKVELSIQKLIQHPGKMFPQISNLRGVN ADSSMPGQLHWEVGFFGKTQFRKALRTDGHDVKLPKELAGKPEFQEEHGTVDTKDEDDVIHTPPDPLWPSGILSI VVHQIVGLELANIKGSDGNRKGKEYEPARPEAGEVKEEQSRKLPSSYCTILVNDDLVYKTRTKVVASQPIFNAGT EKFVRDWRSCIVTVAVRDSRNRQHDPIIGVVPLKLSDVLQTSSESTRWYPLDGGIGFGRVRISLLFRCVELRLPP PQLGWDIGTFEFLSETIVTTNYAPSSHVKVKLRTGGSSATIKKHFSRREETGMAIDICGGQEGHKLRLPVRYRYR SPIFMEFYPLGRRKPDAYASLWLLELTDGEEKEFDIPLFKCDMSLRLSQNYITQENYKEIPDIEIEEIGRVKFRG RFSAGTDSDHIRFVSDNDSRETIEAWEACYAEGVRQEEVDAEVPPLVQKLHDESLTHGRDVLAQADEKDKKRWLS KDGTDWSGAFGKDPRDLMAEKKTKQKQNGDGSRHEDDDYEYDEQDEEDSDESAQWDEEDDDQVPDLGIHDSHDDN YEGNVAGRERPSVDTQATWATESSHESGGSKNPIKAYKDYRTRSRDLHRKHRGLMQWRPMRNAQFAKDEAKFALK KVKKLTSLGGREPDVETEV*
Coding	>OphauG2\|4172 ATGAATGTCGACGAGCACATGGCGCCTTCGGGCCAGCACTACAGCGGCAGCAACCGCGTGCCCAACATCCAGGAG TTTATGGAACAGCTTGACAGCGAGAAGCGGGAGCGAGACGCTGCCATTGATCGAGACCTTAATAGAAACAAGCGC TCCAAGGAGGCAAAGGACCACCGCAATTCAGATGCTCCCAAGCACAAGGATACGCGTACCGTTCGTGATCCCGTC ACGGGCAAGGATGTGCAGATTCGCGATGCCCAGATGGACTTTTGCGAAGCGGTCGACAGGCCCCAGCTCTCGATA CCAAACGAAAACCTGGGAAAGCCCACCACGGTAAGGGTCACGTCACAGCAATCCGGAGAGGAGTACCGCCGTGCA CAAGACATTGCAGCGCCACCCGATCCCATACAAGAAGGCGCCACCTCGGATGTGCCTATTCGAAGCGAAAAGACG TCTGTCCTCTTCTTCAAGACGCCCTCGGTCAGTTATGAGCCCATGTTTGTCTCGCTGGAACGAAAAGCAAATGTC TTGTGCATTGCCATTTCCGTTGCCATTGTAGTCGTTGGCAAGGTCTTTGGTGGAAAGCTACTCGGCCTCGTGCCT CTGGCCGGGTTCGTCTCGGCCGCCGTCTTTCTCTGGATCAAGGACTTGATCCGCCAGGGTCGCGACACTGAGTGG GCAAGCGAGCAGGACCGCGGCGAGACTGCCACGGTCAACCTGATTCCCGAGTCAGTCGAGTGGATGAATACTGCC ATTGGCATATTCTGGGGTCTCATTAATCCCGAAATGTTTGCTGCAGTCGCAGATACACTCGAAGATGTCATGGCG GCTTCAGTGCCAGGAGTGGTGGAAAATGTTCGCGTGGCCGACATTTCACAAGGGAATAATCCAATCAGGATCCTC AACATGCGTGCCCTGCCAGATTCGCACGTGCAGGACATCAAGCAACAGATTCATGAGGAGAATGAAAAGAAGATG GATTCCGACGAGCTTGCTGCCGTTGAGCAGGCTGGCGCATTCTACAATCTCGAAGTCTCGGTTGCTTATCACGCC AAACCATCGGGCCAAGACATTGCGTCAAAAGCTAGCAACATGGGCATGCAGCTCGTCTTCTATCTCGGCATCAGA GGCCTGTTTGGAGTGCCGCTGCCCGTTTGGGTCGAGCTGATTGGCCTGGTGGCTACAGCTCGCATTCGCTTCCAG CTAACTCCTGACCCTCCCTTCCTCAAAACGGTTACTGTCACTCTGATGGGCATTCCAAAGGTTCAGGCTGGTTGT ACGCCCATGATTGAAAGGGGCGTCAATATCCTGAACCTGCCTCTCATCTCAAACTTTGTCAACTGGGCCATTGGG GCAGCAGCATCCATGTACGTGGCGCCCAAGAGCCTGACGCTTGACATGAGCAAGATGCTCCAGGGAGACGACATC AAGAAGGAGACTATAGGTCTGGGCGTCATGTTTATCCGCATTCATAAGGCCACCGGGCTCAGCAAACAGGACCAG CGCGGAAGCAAAGGTGGTGGTTCCGATCCGTACATTACTGTCAGCTGGAGCAAATTCTCCAAGCCCCAGTTCTGT ACTCGCGTCATCCAAGATGACCTTAATCCCGTCTTTGAGGAGACGTGCGGTCTAATCGTGACTAGTGATCTCATC AAGGCCGATGAGCAGCTTTCAATGGAGCTCTGGGACAGTGATCGTTCCTCTGCCGATGACGTGGTGGGCAAGGTG GAGTTGAGCATTCAGAAACTCATTCAGCACCCTGGCAAAATGTTCCCCCAAATCTCCAATCTTCGAGGCGTCAAC GCCGATAGCAGCATGCCTGGCCAGCTTCATTGGGAAGTGGGATTCTTTGGCAAGACCCAGTTCCGCAAGGCTCTG AGGACCGATGGACACGATGTCAAGCTGCCCAAGGAGCTTGCCGGTAAACCCGAGTTTCAAGAAGAACACGGCACC GTTGACACAAAAGATGAAGACGATGTTATACACACGCCTCCCGACCCTCTATGGCCGTCTGGTATTCTGAGTATT GTTGTCCACCAGATTGTTGGCCTGGAGCTTGCTAATATCAAGGGCTCGGATGGTAATCGCAAGGGCAAGGAGTAC GAGCCGGCAAGACCCGAGGCGGGCGAAGTCAAGGAAGAACAGAGCCGCAAGTTGCCCAGCTCATACTGCACGATT CTTGTCAATGATGATCTGGTGTACAAGACGCGGACCAAGGTGGTTGCCTCGCAGCCCATTTTTAACGCCGGGACG GAGAAGTTTGTGCGAGACTGGCGGTCTTGTATTGTGACGGTTGCCGTGCGCGACTCTCGCAATCGACAGCATGAC CCCATAATTGGCGTGGTGCCTCTCAAGCTGTCAGATGTACTGCAAACCAGCAGCGAATCGACGCGGTGGTATCCT CTTGACGGTGGAATTGGCTTTGGGCGAGTCCGCATTTCTCTGCTCTTTCGCTGCGTCGAGCTTCGATTACCGCCG CCGCAGCTTGGTTGGGACATTGGAACTTTTGAATTTCTATCAGAAACCATTGTGACGACCAATTACGCACCGTCC AGCCATGTCAAGGTGAAACTGCGGACCGGAGGATCCTCTGCCACGATCAAGAAGCATTTTTCAAGGCGGGAGGAA ACGGGAATGGCAATTGATATATGCGGCGGCCAAGAGGGCCACAAGTTGCGATTGCCTGTGCGCTATAGGTATCGC TCGCCCATATTTATGGAGTTTTATCCGTTGGGCCGGCGGAAGCCAGACGCATACGCCTCTCTCTGGCTGCTGGAG CTTACTGATGGAGAGGAAAAAGAATTTGATATTCCCTTGTTTAAATGTGACATGAGTCTTCGACTGTCTCAAAAT TATATTACGCAGGAGAACTACAAGGAGATTCCCGACATTGAAATCGAGGAAATTGGGCGTGTCAAGTTCCGCGGC CGCTTTTCTGCGGGGACCGACTCGGATCACATCCGCTTCGTGAGCGACAATGATTCACGCGAGACAATCGAGGCA TGGGAGGCTTGCTATGCCGAGGGAGTGAGGCAGGAAGAAGTCGATGCAGAGGTGCCTCCCTTGGTGCAGAAATTG CATGATGAGTCCCTGACGCATGGACGCGATGTGCTGGCCCAAGCCGACGAAAAGGACAAGAAGCGTTGGCTTTCC AAGGACGGCACGGACTGGAGCGGCGCTTTTGGAAAGGACCCGAGGGACCTCATGGCTGAGAAGAAGACGAAGCAG AAGCAGAATGGTGATGGCTCACGTCATGAAGATGACGATTACGAATATGATGAGCAAGATGAGGAAGATAGCGAC GAAAGTGCACAATGGGACGAAGAAGACGACGACCAAGTCCCGGATCTGGGAATCCATGACAGCCACGACGACAAT TATGAGGGCAATGTGGCAGGGCGAGAGCGACCATCGGTGGACACACAAGCAACGTGGGCTACCGAGTCGTCGCAT GAGAGCGGCGGCAGCAAGAATCCCATCAAGGCGTACAAGGACTACCGCACACGCAGCCGCGATCTTCATCGCAAG CATCGTGGGCTGATGCAATGGCGACCGATGCGCAACGCGCAGTTTGCCAAAGATGAAGCCAAGTTTGCTTTGAAA AAGGTCAAGAAGCTGACTTCTCTTGGAGGGCGAGAGCCCGACGTGGAGACGGAGGTCTAA
Transcript	>OphauG2\|4172 ATGAATGTCGACGAGCACATGGCGCCTTCGGGCCAGCACTACAGCGGCAGCAACCGCGTGCCCAACATCCAGGAG TTTATGGAACAGCTTGACAGCGAGAAGCGGGAGCGAGACGCTGCCATTGATCGAGACCTTAATAGAAACAAGCGC TCCAAGGAGGCAAAGGACCACCGCAATTCAGATGCTCCCAAGCACAAGGATACGCGTACCGTTCGTGATCCCGTC ACGGGCAAGGATGTGCAGATTCGCGATGCCCAGATGGACTTTTGCGAAGCGGTCGACAGGCCCCAGCTCTCGATA CCAAACGAAAACCTGGGAAAGCCCACCACGGTAAGGGTCACGTCACAGCAATCCGGAGAGGAGTACCGCCGTGCA CAAGACATTGCAGCGCCACCCGATCCCATACAAGAAGGCGCCACCTCGGATGTGCCTATTCGAAGCGAAAAGACG TCTGTCCTCTTCTTCAAGACGCCCTCGGTCAGTTATGAGCCCATGTTTGTCTCGCTGGAACGAAAAGCAAATGTC TTGTGCATTGCCATTTCCGTTGCCATTGTAGTCGTTGGCAAGGTCTTTGGTGGAAAGCTACTCGGCCTCGTGCCT CTGGCCGGGTTCGTCTCGGCCGCCGTCTTTCTCTGGATCAAGGACTTGATCCGCCAGGGTCGCGACACTGAGTGG GCAAGCGAGCAGGACCGCGGCGAGACTGCCACGGTCAACCTGATTCCCGAGTCAGTCGAGTGGATGAATACTGCC ATTGGCATATTCTGGGGTCTCATTAATCCCGAAATGTTTGCTGCAGTCGCAGATACACTCGAAGATGTCATGGCG GCTTCAGTGCCAGGAGTGGTGGAAAATGTTCGCGTGGCCGACATTTCACAAGGGAATAATCCAATCAGGATCCTC AACATGCGTGCCCTGCCAGATTCGCACGTGCAGGACATCAAGCAACAGATTCATGAGGAGAATGAAAAGAAGATG GATTCCGACGAGCTTGCTGCCGTTGAGCAGGCTGGCGCATTCTACAATCTCGAAGTCTCGGTTGCTTATCACGCC AAACCATCGGGCCAAGACATTGCGTCAAAAGCTAGCAACATGGGCATGCAGCTCGTCTTCTATCTCGGCATCAGA GGCCTGTTTGGAGTGCCGCTGCCCGTTTGGGTCGAGCTGATTGGCCTGGTGGCTACAGCTCGCATTCGCTTCCAG CTAACTCCTGACCCTCCCTTCCTCAAAACGGTTACTGTCACTCTGATGGGCATTCCAAAGGTTCAGGCTGGTTGT ACGCCCATGATTGAAAGGGGCGTCAATATCCTGAACCTGCCTCTCATCTCAAACTTTGTCAACTGGGCCATTGGG GCAGCAGCATCCATGTACGTGGCGCCCAAGAGCCTGACGCTTGACATGAGCAAGATGCTCCAGGGAGACGACATC AAGAAGGAGACTATAGGTCTGGGCGTCATGTTTATCCGCATTCATAAGGCCACCGGGCTCAGCAAACAGGACCAG CGCGGAAGCAAAGGTGGTGGTTCCGATCCGTACATTACTGTCAGCTGGAGCAAATTCTCCAAGCCCCAGTTCTGT ACTCGCGTCATCCAAGATGACCTTAATCCCGTCTTTGAGGAGACGTGCGGTCTAATCGTGACTAGTGATCTCATC AAGGCCGATGAGCAGCTTTCAATGGAGCTCTGGGACAGTGATCGTTCCTCTGCCGATGACGTGGTGGGCAAGGTG GAGTTGAGCATTCAGAAACTCATTCAGCACCCTGGCAAAATGTTCCCCCAAATCTCCAATCTTCGAGGCGTCAAC GCCGATAGCAGCATGCCTGGCCAGCTTCATTGGGAAGTGGGATTCTTTGGCAAGACCCAGTTCCGCAAGGCTCTG AGGACCGATGGACACGATGTCAAGCTGCCCAAGGAGCTTGCCGGTAAACCCGAGTTTCAAGAAGAACACGGCACC GTTGACACAAAAGATGAAGACGATGTTATACACACGCCTCCCGACCCTCTATGGCCGTCTGGTATTCTGAGTATT GTTGTCCACCAGATTGTTGGCCTGGAGCTTGCTAATATCAAGGGCTCGGATGGTAATCGCAAGGGCAAGGAGTAC GAGCCGGCAAGACCCGAGGCGGGCGAAGTCAAGGAAGAACAGAGCCGCAAGTTGCCCAGCTCATACTGCACGATT CTTGTCAATGATGATCTGGTGTACAAGACGCGGACCAAGGTGGTTGCCTCGCAGCCCATTTTTAACGCCGGGACG GAGAAGTTTGTGCGAGACTGGCGGTCTTGTATTGTGACGGTTGCCGTGCGCGACTCTCGCAATCGACAGCATGAC CCCATAATTGGCGTGGTGCCTCTCAAGCTGTCAGATGTACTGCAAACCAGCAGCGAATCGACGCGGTGGTATCCT CTTGACGGTGGAATTGGCTTTGGGCGAGTCCGCATTTCTCTGCTCTTTCGCTGCGTCGAGCTTCGATTACCGCCG CCGCAGCTTGGTTGGGACATTGGAACTTTTGAATTTCTATCAGAAACCATTGTGACGACCAATTACGCACCGTCC AGCCATGTCAAGGTGAAACTGCGGACCGGAGGATCCTCTGCCACGATCAAGAAGCATTTTTCAAGGCGGGAGGAA ACGGGAATGGCAATTGATATATGCGGCGGCCAAGAGGGCCACAAGTTGCGATTGCCTGTGCGCTATAGGTATCGC TCGCCCATATTTATGGAGTTTTATCCGTTGGGCCGGCGGAAGCCAGACGCATACGCCTCTCTCTGGCTGCTGGAG CTTACTGATGGAGAGGAAAAAGAATTTGATATTCCCTTGTTTAAATGTGACATGAGTCTTCGACTGTCTCAAAAT TATATTACGCAGGAGAACTACAAGGAGATTCCCGACATTGAAATCGAGGAAATTGGGCGTGTCAAGTTCCGCGGC CGCTTTTCTGCGGGGACCGACTCGGATCACATCCGCTTCGTGAGCGACAATGATTCACGCGAGACAATCGAGGCA TGGGAGGCTTGCTATGCCGAGGGAGTGAGGCAGGAAGAAGTCGATGCAGAGGTGCCTCCCTTGGTGCAGAAATTG CATGATGAGTCCCTGACGCATGGACGCGATGTGCTGGCCCAAGCCGACGAAAAGGACAAGAAGCGTTGGCTTTCC AAGGACGGCACGGACTGGAGCGGCGCTTTTGGAAAGGACCCGAGGGACCTCATGGCTGAGAAGAAGACGAAGCAG AAGCAGAATGGTGATGGCTCACGTCATGAAGATGACGATTACGAATATGATGAGCAAGATGAGGAAGATAGCGAC GAAAGTGCACAATGGGACGAAGAAGACGACGACCAAGTCCCGGATCTGGGAATCCATGACAGCCACGACGACAAT TATGAGGGCAATGTGGCAGGGCGAGAGCGACCATCGGTGGACACACAAGCAACGTGGGCTACCGAGTCGTCGCAT GAGAGCGGCGGCAGCAAGAATCCCATCAAGGCGTACAAGGACTACCGCACACGCAGCCGCGATCTTCATCGCAAG CATCGTGGGCTGATGCAATGGCGACCGATGCGCAACGCGCAGTTTGCCAAAGATGAAGCCAAGTTTGCTTTGAAA AAGGTCAAGAAGCTGACTTCTCTTGGAGGGCGAGAGCCCGACGTGGAGACGGAGGTCTAA
Gene	>OphauG2\|4172 ATGAATGTCGACGAGCACATGGCGCCTTCGGGCCAGCACTACAGCGGCAGCAACCGCGTGCCCAACATCCAGGAG TTTATGGAACAGCTTGACAGCGAGAAGCGGGAGCGAGACGCTGCCATTGATCGAGACCTTAATAGAAACAAGCGC TCCAAGGAGGCAAAGGACCACCGCAATTCAGATGCTCCCAAGCACAAGGATACGCGTACCGTTCGTGATCCCGTC ACGGGCAAGGATGTGCAGATTCGCGATGCCCAGATGGACTTTTGCGAAGCGGTCGACAGGCCCCAGGTCAGTTGA ATGCTACTGCCTCGCTACTCCTTGACTCCATTTCCTTGTCAGAGCTAACATCAAGCTTGCCAAGCTCTCGATACC AAACGAAAACCTGGGAAAGCCCACCACGGTAAGGGTCACGTCACAGCAATCCGGAGAGGAGTACCGCCGTGCACA AGACATTGCAGCGCCACCCGATCCCATACAAGAAGGCGCCACCTCGGATGTGCCTATTCGAAGCGAAAAGACGTC TGTCCTCTTCTTCAAGACGCCCTCGGTCAGTTATGAGCCCATGTTTGTCTCGCTGGAACGAAAAGCAAATGTCTT GTGCATTGCCATTTCCGTTGCCATTGTAGTCGTTGGCAAGGTCTTTGGTGGAAAGCTACTCGGCCTCGTGCCTCT GGCCGGGTTCGTCTCGGCCGCCGTCTTTCTCTGGATCAAGGACTTGATCCGCCAGGGTCGCGACACTGAGTGGGC AAGCGAGCAGGACCGCGGCGAGACTGCCACGGTCAACCTGATTCCCGAGTCAGTCGAGTGGATGAATACTGCCAT TGGCATATTCTGGGGTCTCATTAATCCCGAAATGTTTGCTGCAGTCGCAGATACGTGAGTGCAAACCACAGCCCG TCTCCGTCTCTTGTACACATGAGCTGACTGGGGCTTGGAAATAGACTCGAAGATGTCATGGCGGCTTCAGTGCCA GGAGTGGTGGAAAATGTTCGCGTGGCCGACATTTCACAAGGGAATAATCCAATCAGGATCCTCAACATGCGTGCC CTGCCAGATTCGCACGTGCAGGACATCAAGCAACAGATTCATGAGGAGAATGAAAAGAAGATGGATTCCGACGAG CTTGCTGCCGTTGAGCAGGCTGGCGCATTCTACAATCTCGAAGTCTCGGTTGCTTATCACGCCAAACCATCGGGC CAAGACATTGCGTCAAAAGCTAGCAACATGGGCATGCAGCTCGTCTTCTATCTCGGCATCAGAGGCCTGTTTGGA GTGCCGCTGCCCGTTTGGGTCGAGCTGATTGGCCTGGTGGCTACAGCTCGCATTCGCTTCCAGCTAACTCCTGAC CCTCCCTTCCTCAAAACGGTTACTGTCACTCTGATGGGCATTCCAAAGGTTCAGGCTGGTTGTACGCCCATGATT GAAAGGGGCGTCAATATCCTGAACCTGCCTCTCATCTCAAACTTTGTCAACTGGGCCATTGGGGCAGCAGCATCC ATGTACGTGGCGCCCAAGAGCCTGACGCTTGACATGAGCAAGATGCTCCAGGGAGACGACATCAAGAAGGAGACT ATAGGTCTGGGCGTCATGTTTATCCGCATTCATAAGGCCACCGGGCTCAGCAAACAGGACCAGCGCGGAAGCAAA GGTGGTGGTTCCGATCCGTACATTACTGTCAGCTGGAGCAAATTCTCCAAGCCCCAGTTCTGTACTCGCGTCATC CAAGATGACCTTAATCCCGTCTTTGAGGAGACGTGCGGTCTAATCGTGACTAGTGATCTCATCAAGGCCGATGAG CAGCTTTCAATGGAGCTCTGGGACAGTGATCGTTCCTCTGCCGATGACGTGGTGGGCAAGGTGGAGTTGAGCATT CAGAAACTCATTCAGCACCCTGGCAAAATGTTCCCCCAAATCTCCAATCTTCGAGGCGTCAACGCCGATAGCAGC ATGCCTGGCCAGCTTCATTGGGAAGTGGGATTCTTTGGCAAGACCCAGTTCCGCAAGGCTCTGAGGACCGATGGA CACGATGTCAAGCTGCCCAAGGAGCTTGCCGGTAAACCCGAGTTTCAAGAAGAACACGGCACCGTTGACACAAAA GATGAAGACGATGTTATACACACGCCTCCCGACCCTCTATGGCCGTCTGGTATTCTGAGTATTGTTGTCCACCAG ATTGTTGGCCTGGAGCTTGCTAATATCAAGGGCTCGGATGGTAATCGCAAGGGCAAGGAGTACGAGCCGGCAAGA CCCGAGGCGGGCGAAGTCAAGGAAGAACAGAGCCGCAAGTTGCCCAGCTCATACTGCACGATTCTTGTCAATGAT GATCTGGTGTACAAGACGCGGACCAAGGTGGTTGCCTCGCAGCCCATTTTTAACGCCGGGACGGAGAAGTTTGTG CGAGACTGGCGGTCTTGTATTGTGACGGTTGCCGTGCGCGACTCTCGCAATCGACAGCATGACCCCATAATTGGC GTGGTGCCTCTCAAGCTGTCAGATGTACTGCAAACCAGCAGCGAATCGACGCGGTGGTATCCTCTTGACGGTGGA ATTGGCTTTGGGCGAGTCCGCATTTCTCTGCTCTTTCGCTGCGTCGAGCTTCGATTACCGCCGCCGCAGCTTGGT TGGGACATTGGAACTTTTGAATTTCTATCAGAAACCATTGTGACGACCAATTACGCACCGTCCAGCCATGTCAAG GTGAAACTGCGGACCGGAGGATCCTCTGCCACGATCAAGAAGCATTTTTCAAGGCGGGAGGAAACGGGAATGGCA ATTGATATATGCGGCGGCCAAGAGGGCCACAAGTTGCGATTGCCTGTGCGCTATAGGTATCGCTCGCCCATATTT ATGGAGTTTTATCCGTTGGGCCGGCGGAAGCCAGACGCATACGCCTCTCTCTGGCTGCTGGAGCTTACTGATGGA GAGGAAAAAGAATTTGATATTCCCTTGTTTAAATGTGACATGAGTCTTCGACTGTCTCAAAATTATATTACGCAG GAGAACTACAAGGAGATTCCCGACATTGAAATCGAGGAAATTGGGCGTGTCAAGTTCCGCGGCCGCTTTTCTGCG GGGACCGACTCGGATCACATCCGCTTCGTGAGCGACAATGATTCACGCGAGACAATCGAGGCATGGGAGGCTTGC TATGCCGAGGGAGTGAGGCAGGAAGAAGTCGATGCAGAGGTGCCTCCCTTGGTGCAGAAATTGCATGATGAGTCC CTGACGCATGGACGCGATGTGCTGGCCCAAGCCGACGAAAAGGACAAGAAGCGTTGGCTTTCCAAGGACGGCACG GACTGGAGCGGCGCTTTTGGAAAGGACCCGAGGGACCTCATGGCTGAGAAGAAGACGAAGCAGAAGCAGAATGGT GATGGCTCACGTCATGAAGATGACGATTACGAATATGATGAGCAAGATGAGGAAGATAGCGACGAAAGTGCACAA TGGGACGAAGAAGACGACGACCAAGTCCCGGATCTGGGAATCCATGACAGCCACGACGACAATTATGAGGGCAAT GTGGCAGGGCGAGAGCGACCATCGGTGGACACACAAGCAACGTGGGCTACCGAGTCGTCGCATGAGAGCGGCGGC AGCAAGAATCCCATCAAGGCGTACAAGGACTACCGCACACGCAGCCGCGATCTTCATCGCAAGCATCGTGGGCTG ATGCAATGGCGACCGATGCGCAACGCGCAGTTTGCCAAAGATGAAGCCAAGTTTGCTTTGAAAAAGGTCAAGAAG CTGACTTCTCTTGGAGGGCGAGAGCCCGACGTGGAGACGGAGGTCTAA

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