© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | OphauB2|4717 |
| Gene name | |
| Location | Contig_32:109551..112284 |
| Strand | + |
| Gene length (bp) | 2733 |
| Transcript length (bp) | 2469 |
| Coding sequence length (bp) | 2469 |
| Protein length (aa) | 823 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF13086 | AAA_11 | AAA domain | 2.9E-23 | 289 | 655 |
| PF13087 | AAA_12 | AAA domain | 1.1E-21 | 668 | 819 |
| PF13245 | AAA_19 | AAA domain | 1.2E-08 | 294 | 654 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O74465|HRR1_SCHPO | Helicase required for RNAi-mediated heterochromatin assembly 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=hrr1 PE=1 SV=2 | 35 | 820 | 4.0E-94 |
| sp|Q9P2E3|ZNFX1_HUMAN | NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=2 SV=2 | 534 | 820 | 7.0E-43 |
| sp|Q8R151|ZNFX1_MOUSE | NFX1-type zinc finger-containing protein 1 OS=Mus musculus GN=Znfx1 PE=1 SV=3 | 534 | 820 | 1.0E-42 |
| sp|Q9P2E3|ZNFX1_HUMAN | NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=2 SV=2 | 40 | 374 | 5.0E-20 |
| sp|Q9FJR0|RENT1_ARATH | Regulator of nonsense transcripts 1 homolog OS=Arabidopsis thaliana GN=UPF1 PE=1 SV=2 | 518 | 820 | 3.0E-19 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O74465|HRR1_SCHPO | Helicase required for RNAi-mediated heterochromatin assembly 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=hrr1 PE=1 SV=2 | 35 | 820 | 4.0E-94 |
| sp|Q9P2E3|ZNFX1_HUMAN | NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=2 SV=2 | 534 | 820 | 7.0E-43 |
| sp|Q8R151|ZNFX1_MOUSE | NFX1-type zinc finger-containing protein 1 OS=Mus musculus GN=Znfx1 PE=1 SV=3 | 534 | 820 | 1.0E-42 |
| sp|Q9P2E3|ZNFX1_HUMAN | NFX1-type zinc finger-containing protein 1 OS=Homo sapiens GN=ZNFX1 PE=2 SV=2 | 40 | 374 | 5.0E-20 |
| sp|Q9FJR0|RENT1_ARATH | Regulator of nonsense transcripts 1 homolog OS=Arabidopsis thaliana GN=UPF1 PE=1 SV=2 | 518 | 820 | 3.0E-19 |
| sp|Q8R151|ZNFX1_MOUSE | NFX1-type zinc finger-containing protein 1 OS=Mus musculus GN=Znfx1 PE=1 SV=3 | 40 | 374 | 7.0E-19 |
| sp|O76512|RENT1_CAEEL | Regulator of nonsense transcripts 1 OS=Caenorhabditis elegans GN=smg-2 PE=1 SV=1 | 595 | 820 | 4.0E-18 |
| sp|Q9HEH1|RENT1_NEUCR | Regulator of nonsense transcripts 1 homolog OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=2E4.130 PE=3 SV=1 | 547 | 820 | 8.0E-18 |
| sp|Q9VYS3|RENT1_DROME | Regulator of nonsense transcripts 1 homolog OS=Drosophila melanogaster GN=Upf1 PE=1 SV=2 | 547 | 820 | 5.0E-16 |
| sp|P30771|NAM7_YEAST | ATP-dependent helicase NAM7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAM7 PE=1 SV=1 | 576 | 820 | 1.0E-15 |
| sp|Q9EPU0|RENT1_MOUSE | Regulator of nonsense transcripts 1 OS=Mus musculus GN=Upf1 PE=1 SV=2 | 518 | 820 | 3.0E-15 |
| sp|Q92900|RENT1_HUMAN | Regulator of nonsense transcripts 1 OS=Homo sapiens GN=UPF1 PE=1 SV=2 | 518 | 820 | 3.0E-15 |
| sp|Q09820|RENT1_SCHPO | ATP-dependent helicase upf1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=upf1 PE=3 SV=2 | 550 | 818 | 1.0E-14 |
| sp|Q8CFQ3|AQR_MOUSE | Intron-binding protein aquarius OS=Mus musculus GN=Aqr PE=1 SV=2 | 560 | 820 | 4.0E-14 |
| sp|O60306|AQR_HUMAN | Intron-binding protein aquarius OS=Homo sapiens GN=AQR PE=1 SV=4 | 560 | 820 | 4.0E-14 |
| sp|Q54I89|RENT1_DICDI | Regulator of nonsense transcripts 1 OS=Dictyostelium discoideum GN=upf1 PE=3 SV=1 | 544 | 820 | 2.0E-13 |
| sp|Q57568|Y104_METJA | Uncharacterized ATP-dependent helicase MJ0104 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) GN=MJ0104 PE=3 SV=1 | 617 | 820 | 8.0E-10 |
| sp|Q0VGT4|ZGRF1_MOUSE | Protein ZGRF1 OS=Mus musculus GN=Zgrf1 PE=1 SV=2 | 593 | 820 | 2.0E-09 |
| sp|Q92355|SEN1_SCHPO | Helicase sen1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sen1 PE=1 SV=1 | 550 | 818 | 2.0E-09 |
| sp|P34243|HCS1_YEAST | DNA polymerase alpha-associated DNA helicase A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HCS1 PE=1 SV=1 | 641 | 820 | 3.0E-09 |
| sp|Q98TR3|RENT1_TAKRU | Putative regulator of nonsense transcripts 1 OS=Takifugu rubripes GN=rent1 PE=3 SV=1 | 518 | 820 | 4.0E-09 |
| sp|Q09820|RENT1_SCHPO | ATP-dependent helicase upf1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=upf1 PE=3 SV=2 | 229 | 380 | 4.0E-09 |
| sp|Q9HEH1|RENT1_NEUCR | Regulator of nonsense transcripts 1 homolog OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=2E4.130 PE=3 SV=1 | 243 | 420 | 1.0E-08 |
| sp|Q86YA3|ZGRF1_HUMAN | Protein ZGRF1 OS=Homo sapiens GN=ZGRF1 PE=2 SV=3 | 593 | 820 | 1.0E-08 |
| sp|Q86AS0|Y4399_DICDI | Probable helicase DDB_G0274399 OS=Dictyostelium discoideum GN=DDB_G0274399 PE=3 SV=1 | 617 | 818 | 7.0E-08 |
| sp|Q9EQN5|SMBP2_RAT | DNA-binding protein SMUBP-2 OS=Rattus norvegicus GN=Ighmbp2 PE=1 SV=1 | 533 | 820 | 2.0E-07 |
| sp|O94247|HCS1_SCHPO | DNA polymerase alpha-associated DNA helicase A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=hcs1 PE=3 SV=1 | 574 | 820 | 3.0E-07 |
| sp|P30771|NAM7_YEAST | ATP-dependent helicase NAM7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAM7 PE=1 SV=1 | 285 | 440 | 4.0E-07 |
| sp|Q60560|SMBP2_MESAU | DNA-binding protein SMUBP-2 OS=Mesocricetus auratus GN=IGHMBP2 PE=1 SV=1 | 617 | 820 | 4.0E-07 |
| sp|P40694|SMBP2_MOUSE | DNA-binding protein SMUBP-2 OS=Mus musculus GN=Ighmbp2 PE=1 SV=1 | 617 | 820 | 1.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0004386 | helicase activity | Yes |
| GO:0003824 | catalytic activity | No |
| GO:0140657 | ATP-dependent activity | No |
| GO:0003674 | molecular_function | No |
| GO:0140640 | catalytic activity, acting on a nucleic acid | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 20 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >OphauB2|4717 MPFVAVQAGLVSRSSPTSSQLFLSRRFSSSALNMASTTTAWKEMPEIPTAEELLSPHNSALPQILEHGAMTKEEY LEAQYLLHRHEATASLRAAVQQIRHGDLALGSEDANIYTKVRVLGFRPTKSGVAWRIVWKPNSPGHLMSISQPDC LPSGTLVILSPKADSFRTQCLVATVAQKHPDEVQTARESSSCEIIWARCEDAILDPDVELIMLEPESGYFEPSRH IMKGLKLAASASSRYDKYLFKTKNGASEKNEPVTFDEPVKSHVSADFLRLASKREPVASPAAVQLDSSQLEAVQQ ATKQELAMIQGPPGTGKTFTSVVTIDSHLRTMEACHPTNDAPPPIIVVAETNHALDQLLTQCMSAGLRSILRLGH NVQEDSVIYNKSLLKLLMRSRVKLPEKKADAKYKQAVKVLTSDLNQVFMDKAFYEAQALHDAELISPKQYLSLIE DDGWETADAQDKRGPVAKWLNHSSVQSQCDPQQPVNNTIPHEGVFPNYIPFGVSTARGLLRSVERDGINDWAIRA VRLLECSSDLYQIPLWQRRHIYCLLHKQMQERSIQNLLQAIKVFDIECEDFKKARSVNDAAVIRGEDIRIIGCTT TGLAKYRRLLEILKPRILLVEEAAEVREGSIVAGLMPCIEQLVLVGDHQQLIPSVDVWELSRSPHRIDISLFERM VKLEVPFCSLRVQRRMAPALRRVMQSFYPHIQDHASVKELPLVPGMSSRRLWWFDHQWEQSQTVGCSFVNTEEAD MIVGFVGYLIQHGMSPSRITVLAYYSGQVALIQRKLKSHPNLARFDFERSVRTIDGFQGEENDVILLSLLWQ* |
| Coding | >OphauB2|4717 ATGCCTTTTGTCGCCGTACAAGCCGGTCTTGTTTCTAGATCCTCTCCAACCTCGTCTCAACTCTTCTTGTCTCGT CGCTTTTCAAGCTCTGCACTCAACATGGCGAGCACCACGACGGCTTGGAAGGAAATGCCCGAAATCCCCACGGCA GAAGAACTGCTATCGCCTCATAACTCGGCACTGCCCCAGATTTTGGAGCATGGAGCAATGACCAAGGAGGAGTAT CTGGAGGCTCAGTACCTCCTCCATCGCCACGAGGCCACGGCATCGCTTCGCGCCGCGGTGCAACAGATCCGCCAC GGAGATCTGGCCTTGGGCTCTGAAGACGCAAACATCTATACCAAAGTACGCGTGTTGGGCTTTCGCCCCACCAAA TCGGGCGTGGCGTGGCGCATCGTCTGGAAGCCGAACTCGCCTGGGCATTTGATGTCAATCAGTCAACCAGATTGC CTGCCATCCGGCACTCTAGTAATCCTGAGCCCCAAGGCCGATTCTTTCCGTACCCAGTGCTTAGTGGCGACAGTA GCCCAAAAACACCCGGACGAAGTCCAAACAGCAAGGGAATCTTCCTCTTGTGAGATTATTTGGGCCCGGTGCGAG GATGCTATCTTGGACCCAGATGTTGAGTTGATCATGCTGGAGCCCGAGAGCGGCTATTTTGAACCGTCTCGGCAC ATCATGAAGGGCCTCAAACTTGCCGCGTCGGCCAGCTCTCGATACGACAAGTACCTATTCAAGACTAAGAATGGT GCTTCCGAAAAGAATGAGCCCGTCACATTCGATGAGCCCGTAAAATCTCACGTTTCTGCAGATTTTCTTCGTTTG GCATCCAAAAGAGAGCCTGTGGCTTCTCCAGCCGCTGTCCAGTTAGACTCTTCACAATTGGAAGCTGTTCAGCAA GCCACCAAGCAAGAGCTCGCCATGATTCAGGGCCCTCCAGGAACGGGCAAGACTTTTACCTCTGTGGTGACGATT GACAGTCATTTGAGAACCATGGAGGCTTGTCATCCCACAAATGACGCTCCACCACCCATCATAGTGGTGGCTGAA ACAAACCATGCATTGGACCAGCTCCTGACTCAATGTATGAGCGCAGGACTCAGGTCCATACTACGTCTTGGCCAC AATGTCCAAGAAGACTCTGTGATCTACAACAAGTCTCTCTTGAAACTTCTCATGCGGTCAAGGGTGAAGCTGCCA GAAAAGAAAGCCGATGCCAAGTACAAGCAAGCAGTCAAGGTGCTCACGTCTGACTTGAACCAAGTTTTCATGGAT AAAGCCTTCTATGAGGCACAAGCGCTGCATGACGCTGAGCTCATTTCGCCGAAACAATACTTGTCGTTGATAGAA GACGACGGCTGGGAGACTGCCGACGCCCAAGATAAACGAGGCCCTGTGGCAAAGTGGCTCAATCACTCCTCTGTT CAAAGCCAATGCGACCCACAACAGCCCGTGAACAACACGATCCCACATGAGGGCGTTTTCCCAAACTATATCCCC TTTGGAGTATCTACGGCCAGAGGCCTATTGCGAAGCGTTGAGCGCGACGGAATAAATGACTGGGCGATCAGGGCT GTTCGCCTATTGGAATGCTCTTCTGATCTTTATCAGATTCCCCTGTGGCAGAGACGACATATCTACTGCCTTCTT CATAAGCAGATGCAGGAACGCTCCATACAAAACCTTTTACAGGCCATCAAGGTATTTGATATTGAGTGCGAAGAT TTCAAAAAGGCCAGATCGGTCAATGATGCGGCCGTTATTCGTGGAGAAGACATTCGCATCATTGGCTGCACTACT ACTGGCTTGGCCAAGTATCGCCGTCTCCTTGAAATCCTGAAGCCTCGAATTTTGTTGGTGGAAGAGGCGGCAGAG GTGCGCGAAGGCAGTATCGTGGCAGGATTGATGCCTTGCATCGAGCAACTTGTCTTGGTTGGAGACCACCAACAA TTGATACCTAGCGTTGACGTTTGGGAGCTCAGCAGAAGCCCACATCGAATCGACATTTCCCTATTTGAGAGAATG GTCAAGCTCGAGGTGCCTTTTTGCTCGTTGCGCGTCCAACGACGCATGGCTCCGGCTCTCCGGCGGGTGATGCAG TCTTTCTATCCTCATATCCAAGACCATGCTAGCGTCAAGGAGCTACCTCTGGTGCCGGGCATGAGTTCGAGACGC CTCTGGTGGTTTGATCACCAATGGGAACAGAGTCAGACAGTTGGGTGTTCGTTTGTAAACACGGAGGAAGCCGAC ATGATTGTTGGCTTCGTCGGTTACTTGATTCAGCATGGCATGTCGCCAAGCCGCATCACGGTGCTGGCATACTAC AGTGGTCAAGTTGCCCTGATACAGAGGAAGCTCAAGAGCCACCCAAACCTTGCCCGTTTTGACTTTGAGCGTTCG GTTCGCACCATTGATGGATTTCAGGGGGAAGAAAACGATGTCATTTTGCTCTCGCTTTTGTGGCAATGA |
| Transcript | >OphauB2|4717 ATGCCTTTTGTCGCCGTACAAGCCGGTCTTGTTTCTAGATCCTCTCCAACCTCGTCTCAACTCTTCTTGTCTCGT CGCTTTTCAAGCTCTGCACTCAACATGGCGAGCACCACGACGGCTTGGAAGGAAATGCCCGAAATCCCCACGGCA GAAGAACTGCTATCGCCTCATAACTCGGCACTGCCCCAGATTTTGGAGCATGGAGCAATGACCAAGGAGGAGTAT CTGGAGGCTCAGTACCTCCTCCATCGCCACGAGGCCACGGCATCGCTTCGCGCCGCGGTGCAACAGATCCGCCAC GGAGATCTGGCCTTGGGCTCTGAAGACGCAAACATCTATACCAAAGTACGCGTGTTGGGCTTTCGCCCCACCAAA TCGGGCGTGGCGTGGCGCATCGTCTGGAAGCCGAACTCGCCTGGGCATTTGATGTCAATCAGTCAACCAGATTGC CTGCCATCCGGCACTCTAGTAATCCTGAGCCCCAAGGCCGATTCTTTCCGTACCCAGTGCTTAGTGGCGACAGTA GCCCAAAAACACCCGGACGAAGTCCAAACAGCAAGGGAATCTTCCTCTTGTGAGATTATTTGGGCCCGGTGCGAG GATGCTATCTTGGACCCAGATGTTGAGTTGATCATGCTGGAGCCCGAGAGCGGCTATTTTGAACCGTCTCGGCAC ATCATGAAGGGCCTCAAACTTGCCGCGTCGGCCAGCTCTCGATACGACAAGTACCTATTCAAGACTAAGAATGGT GCTTCCGAAAAGAATGAGCCCGTCACATTCGATGAGCCCGTAAAATCTCACGTTTCTGCAGATTTTCTTCGTTTG GCATCCAAAAGAGAGCCTGTGGCTTCTCCAGCCGCTGTCCAGTTAGACTCTTCACAATTGGAAGCTGTTCAGCAA GCCACCAAGCAAGAGCTCGCCATGATTCAGGGCCCTCCAGGAACGGGCAAGACTTTTACCTCTGTGGTGACGATT GACAGTCATTTGAGAACCATGGAGGCTTGTCATCCCACAAATGACGCTCCACCACCCATCATAGTGGTGGCTGAA ACAAACCATGCATTGGACCAGCTCCTGACTCAATGTATGAGCGCAGGACTCAGGTCCATACTACGTCTTGGCCAC AATGTCCAAGAAGACTCTGTGATCTACAACAAGTCTCTCTTGAAACTTCTCATGCGGTCAAGGGTGAAGCTGCCA GAAAAGAAAGCCGATGCCAAGTACAAGCAAGCAGTCAAGGTGCTCACGTCTGACTTGAACCAAGTTTTCATGGAT AAAGCCTTCTATGAGGCACAAGCGCTGCATGACGCTGAGCTCATTTCGCCGAAACAATACTTGTCGTTGATAGAA GACGACGGCTGGGAGACTGCCGACGCCCAAGATAAACGAGGCCCTGTGGCAAAGTGGCTCAATCACTCCTCTGTT CAAAGCCAATGCGACCCACAACAGCCCGTGAACAACACGATCCCACATGAGGGCGTTTTCCCAAACTATATCCCC TTTGGAGTATCTACGGCCAGAGGCCTATTGCGAAGCGTTGAGCGCGACGGAATAAATGACTGGGCGATCAGGGCT GTTCGCCTATTGGAATGCTCTTCTGATCTTTATCAGATTCCCCTGTGGCAGAGACGACATATCTACTGCCTTCTT CATAAGCAGATGCAGGAACGCTCCATACAAAACCTTTTACAGGCCATCAAGGTATTTGATATTGAGTGCGAAGAT TTCAAAAAGGCCAGATCGGTCAATGATGCGGCCGTTATTCGTGGAGAAGACATTCGCATCATTGGCTGCACTACT ACTGGCTTGGCCAAGTATCGCCGTCTCCTTGAAATCCTGAAGCCTCGAATTTTGTTGGTGGAAGAGGCGGCAGAG GTGCGCGAAGGCAGTATCGTGGCAGGATTGATGCCTTGCATCGAGCAACTTGTCTTGGTTGGAGACCACCAACAA TTGATACCTAGCGTTGACGTTTGGGAGCTCAGCAGAAGCCCACATCGAATCGACATTTCCCTATTTGAGAGAATG GTCAAGCTCGAGGTGCCTTTTTGCTCGTTGCGCGTCCAACGACGCATGGCTCCGGCTCTCCGGCGGGTGATGCAG TCTTTCTATCCTCATATCCAAGACCATGCTAGCGTCAAGGAGCTACCTCTGGTGCCGGGCATGAGTTCGAGACGC CTCTGGTGGTTTGATCACCAATGGGAACAGAGTCAGACAGTTGGGTGTTCGTTTGTAAACACGGAGGAAGCCGAC ATGATTGTTGGCTTCGTCGGTTACTTGATTCAGCATGGCATGTCGCCAAGCCGCATCACGGTGCTGGCATACTAC AGTGGTCAAGTTGCCCTGATACAGAGGAAGCTCAAGAGCCACCCAAACCTTGCCCGTTTTGACTTTGAGCGTTCG GTTCGCACCATTGATGGATTTCAGGGGGAAGAAAACGATGTCATTTTGCTCTCGCTTTTGTGGCAATGA |
| Gene | >OphauB2|4717 ATGCCTTTTGTCGCCGTACAAGCCGGTCTTGTTTCTAGATCCTCTCCAACCTCGTCTCAACTCTTCTTGTCTCGT CGCTTTTCAAGCTCTGGTGCGTATTCCCTGGCTGCCTTTTGTGTTTGCAGCGCTCATTTTCATCGTCGGTTGCTG ATGGCTTTGGCAAGCACTCAACATGGCGAGCACCACGACGGCTTGGAAGGAAATGCCCGAAATCCCCACGGCAGA AGAACTGCTATCGCCTCATAACTCGGCACTGCCCCAGATTTTGGAGCATGGAGCAATGACCAAGGAGGAGTATCT GGAGGCTCAGTACCTCCTCCATCGCCACGAGGCCACGGCATCGCTTCGCGCCGCGGTGCAACAGATCCGCCACGG AGATCTGGCCTTGGGCTCTGAAGACGCAAACATCTATACCAAAGTATATGCTTTGTTGATGCCTTTATTGGCCTT GTGTTTTACTCATTCTTTGTATAGGTACGCGTGTTGGGCTTTCGCCCCACCAAATCGGGCGTGGCGTGGCGCATC GTCTGGAAGCCGAACTCGCCTGGGCATTTGATGTCAATCAGTCAACCAGATTGCCTGCCATCCGGCACTCTAGTA ATCCTGAGCCCCAAGGCCGATTCTTTCCGTACCCAGTGCTTAGTGGCGACAGTAGCCCAAAAACACCCGGACGAA GTCCAAACAGCAAGGGAATCTTCCTCTTGTGAGATTATTTGGGCCCGGTGCGAGGATGCTATCTTGGACCCAGAT GTTGAGTTGATCATGCTGGAGCCCGAGAGCGGCTATTTTGAACCGTCTCGGCACATCATGAAGGGCCTCAAACTT GCCGCGTCGGCCAGGTATGTTTTTTTAACTGATTAAAGTCTCTTTATTTCTTGCAAACAAGGCTAACATAACAAT CCACAAGCTCTCGATACGACAAGTACCTATTCAAGACTAAGAATGGTGCTTCCGAAAAGAATGAGCCCGTCACAT TCGATGAGCCCGTAAAATCTCACGTTTCTGCAGATTTTCTTCGTTTGGCATCCAAAAGAGAGCCTGTGGCTTCTC CAGCCGCTGTCCAGTTAGACTCTTCACAATTGGAAGCTGTTCAGCAAGCCACCAAGCAAGAGCTCGCCATGATTC AGGGCCCTCCAGGAACGGGCAAGACTTTTACCTCTGTGGTGACGATTGACAGTCATTTGAGAACCATGGAGGCTT GTCATCCCACAAATGACGCTCCACCACCCATCATAGTGGTGGCTGAAACAAACCATGCATTGGACCAGCTCCTGA CTCAATGTATGAGCGCAGGACTCAGGTCCATACTACGTCTTGGCCACAATGTCCAAGAAGACTCTGTGATCTACA ACAAGTCTCTCTTGAAACTTCTCATGCGGTCAAGGGTGAAGCTGCCAGAAAAGAAAGCCGATGCCAAGTACAAGC AAGCAGTCAAGGTGCTCACGTCTGACTTGAACCAAGTTTTCATGGATAAAGCCTTCTATGAGGCACAAGCGCTGC ATGACGCTGAGCTCATTTCGCCGAAACAATACTTGTCGTTGATAGAAGACGACGGCTGGGAGACTGCCGACGCCC AAGATAAACGAGGCCCTGTGGCAAAGTGGCTCAATCACTCCTCTGTTCAAAGCCAATGCGACCCACAACAGCCCG TGAACAACACGATCCCACATGAGGGCGTTTTCCCAAACTATATCCCCTTTGGAGTATCTACGGCCAGAGGCCTAT TGCGAAGCGTTGAGCGCGACGGAATAAATGACTGGGCGATCAGGGCTGTTCGCCTATTGGAATGCTCTTCTGATC TTTATCAGATTCCCCTGTGGCAGAGACGACATATCTACTGCCTTCTTCATAAGCAGATGCAGGAACGCTCCATAC AAAACCTTTTACAGGCCATCAAGGTATTTGATATTGAGTGCGAAGATTTCAAAAAGGCCAGATCGGTCAATGATG CGGCCGTTATTCGTGGAGAAGACATTCGCATCATTGGCTGCACTACTACTGGCTTGGCCAAGTATCGCCGTCTCC TTGAAATCCTGAAGCCTCGAATTTTGTTGGTGGAAGAGGCGGCAGAGGTGCGCGAAGGCAGTATCGTGGCAGGAT TGATGCCTTGCATCGAGCAACTTGTCTTGGTTGGAGACCACCAACAATTGATACCTAGCGTTGACGTTTGGGAGC TCAGCAGAAGCCCACATCGAATCGACATTTCCCTATTTGAGAGAATGGTCAAGCTCGAGGTGCCTTTTTGCTCGT TGCGCGTCCAACGACGCATGGCTCCGGCTCTCCGGCGGGTGATGCAGTCTTTCTATCCTCATATCCAAGACCATG CTAGCGTCAAGGAGCTACCTCTGGTGCCGGGCATGAGTTCGAGACGCCTCTGGTGGTTTGATCACCAATGGGAAC AGAGTCAGACAGTTGGGTGTTCGTTTGTAAACACGGAGGAAGCCGACATGATTGTTGGCTTCGTCGGTTACTTGA TTCAGCATGGCATGTCGCCAAGCCGCATCACGGTGCTGGCATACTACAGTGGTCAAGTTGCCCTGATACAGAGGA AGCTCAAGAGCCACCCAAACCTTGCCCGTTTTGACTTTGAGCGTTCGGTTCGCACCATTGATGGATTTCAGGGGG AAGAAAACGATGTCATTTTGCTCTCGCTTGTGCGAGGCCCCGGAAGCGACGGCGGTCGGGGCAGGGTTGGGTTTT TGGCTGACGAGAACCGAGCAGTTGTGGCAATGA |