Fungal Genomics

at Utrecht University

General Properties

Protein ID	OphauB2\|4465
Gene name
Location	Contig_3:219373..223085
Strand	-
Gene length (bp)	3712
Transcript length (bp)	3558
Coding sequence length (bp)	3558
Protein length (aa)	1186

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF00168	C2	C2 domain	1.2E-12	547	652
PF00168	C2	C2 domain	1.1E-05	768	878

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9USG8\|MU190_SCHPO	Meiotically up-regulated gene 190 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug190 PE=1 SV=1	197	1080	2.0E-135
sp\|Q9BSJ8\|ESYT1_HUMAN	Extended synaptotagmin-1 OS=Homo sapiens GN=ESYT1 PE=1 SV=1	199	610	1.0E-09
sp\|Q3U7R1\|ESYT1_MOUSE	Extended synaptotagmin-1 OS=Mus musculus GN=Esyt1 PE=1 SV=2	195	610	1.0E-09
sp\|Q5M7N9\|ESYT3_XENTR	Extended synaptotagmin-3 OS=Xenopus tropicalis GN=esyt3 PE=2 SV=1	289	650	5.0E-09
sp\|Q5RAG2\|ESYT1_PONAB	Extended synaptotagmin-1 OS=Pongo abelii GN=ESYT1 PE=2 SV=2	199	610	7.0E-09

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9USG8\|MU190_SCHPO	Meiotically up-regulated gene 190 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mug190 PE=1 SV=1	197	1080	2.0E-135
sp\|Q9BSJ8\|ESYT1_HUMAN	Extended synaptotagmin-1 OS=Homo sapiens GN=ESYT1 PE=1 SV=1	199	610	1.0E-09
sp\|Q3U7R1\|ESYT1_MOUSE	Extended synaptotagmin-1 OS=Mus musculus GN=Esyt1 PE=1 SV=2	195	610	1.0E-09
sp\|Q5M7N9\|ESYT3_XENTR	Extended synaptotagmin-3 OS=Xenopus tropicalis GN=esyt3 PE=2 SV=1	289	650	5.0E-09
sp\|Q5RAG2\|ESYT1_PONAB	Extended synaptotagmin-1 OS=Pongo abelii GN=ESYT1 PE=2 SV=2	199	610	7.0E-09
sp\|Q9Z1X1\|ESYT1_RAT	Extended synaptotagmin-1 OS=Rattus norvegicus GN=Esyt1 PE=1 SV=1	195	610	2.0E-08
sp\|A0FGR8\|ESYT2_HUMAN	Extended synaptotagmin-2 OS=Homo sapiens GN=ESYT2 PE=1 SV=1	454	647	6.0E-08
sp\|Q3TZZ7\|ESYT2_MOUSE	Extended synaptotagmin-2 OS=Mus musculus GN=Esyt2 PE=1 SV=1	454	647	5.0E-07
sp\|Q7ZWU7\|EST2B_XENLA	Extended synaptotagmin-2-B OS=Xenopus laevis GN=esyt2-b PE=2 SV=1	289	647	2.0E-06
sp\|Q5FWL4\|EST2A_XENLA	Extended synaptotagmin-2-A OS=Xenopus laevis GN=esyt2-a PE=2 SV=1	456	647	4.0E-06
sp\|Q9R0N6\|SYT8_MOUSE	Synaptotagmin-8 OS=Mus musculus GN=Syt8 PE=1 SV=1	546	651	5.0E-06

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 54	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	216	235	19
2	240	262	22

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>OphauB2\|4465 MSAKDDADDVKRYQAPYSAQRPIPTISRYREIKAARRREAAFRRQEDGDDDDQTALLPSWAQNNQPLGRSRSQSR TSLQSQTDVPTADTKSELSTLEDTSQVDAAATDVKQRRKRLKSSSRHKERAQREVTDPVTHLPVTIQDFTDEALE ALDYNHAAPGSTPETATGRDAKLKTTEQLFTEQQSLQRNHNALRSRFPPPDMAAMGQELVSLHRRIAIVAVSVAA LVALAASFVVRCSNLTAWLGLAVAAVALIAGVQDYASDQVLSTFKDEIWESQRRQVESRSSSYEVEPTVWLNSLL GSVWPLINPDLFVSLSDTLEDVMQASLPRLVRMVSVEDIGQGSEAIRILGIRWLPTGAAAKTVTRDGKLSSDESY DNDVDQEKPRSEEEKDAEKAFAGMRAEEGDFVNMEVAFAYRSRPRSHRIKDRTKSMHLYLAFYLPGNVKIPVWVD LRGIVGVLRVRLQLTPDPPFFSLCTLTLLGQPKVDLSCIPLSQRGLNIMDVPLISNFVQSAVDAAVADYVAPKSL TLDLKDMLAGDDFKKDTVSTGVLMVNIKRGYDFKMGDTAIPLIRDGSSDPYVSVGWAKFGKVLWSTRVLECEMEP YWDETCFVLVTPEELNIDERLRVQLWDSDRFTADDDLGRIEVPLAELLTDHRSRAKMWERVDGFRALSAGDNMPG KLEWSVGYFAKTALQQCQLDLQTHDCKVRTMQQLQVKVDKSCERKLREIVVKQGHEEDDEAEVERQRALELKTEQ DAIIISAPPPDGYPSGLLSLQIHNITGLELDKLSKRQVEDEEEASDEEEAGDSLPSAYCTVIINHSKTFKTRIKP QNAKPFFNAGCERFIRDWRDCEVFVSVRDARLHEENPLLGIVHLPLSHVLRERSQVMGFWPLSGGIGHGRIRLSL VWRSINLQVPRNMLGWSYGTLDVEPVATSSDCPAQLSSCQLKLKTNISMGKLYAHQGGEGKAEWRTKREQNVSLA VKKRYSSCMSVSFRNKKGLFGDKVASFCVMWLKDIADEEEQELELPIWKGDFERATACCLKECGERVGTLKLKVT FLAGMGNAHARWASRNQDLRDVIEVIETARDNLDGDEMEKAAGIGDEDASSDSDSSSGEKDEADGKSLKEKQSTL EQIRDYRRRDKALHRQHRGIMQWKIPRTAKWVKNKWGRVEDGVTGFFEHGSRQAGIETEV*
Coding	>OphauB2\|4465 ATGTCGGCCAAGGATGACGCCGACGATGTGAAGCGGTACCAAGCCCCCTACAGTGCCCAGCGGCCCATTCCCACC ATTTCCCGCTACCGAGAGATCAAGGCAGCACGCCGACGCGAGGCTGCATTCCGGCGGCAAGAGGATGGCGACGAC GACGACCAAACAGCACTGCTGCCTTCTTGGGCCCAGAATAATCAGCCTCTAGGCCGCTCCCGGAGCCAGTCTCGG ACAAGTCTGCAATCACAGACGGACGTGCCCACAGCCGACACCAAGAGTGAGCTCTCGACACTTGAGGATACGTCG CAGGTCGACGCCGCAGCAACAGATGTCAAGCAGAGGCGCAAGCGGCTCAAGTCGAGCTCCAGACACAAGGAGCGT GCCCAGCGCGAGGTTACCGATCCCGTCACCCATTTGCCCGTCACCATTCAAGACTTCACCGACGAGGCCCTCGAG GCTCTCGACTATAACCATGCGGCCCCCGGCTCCACGCCAGAAACCGCCACGGGTCGCGATGCCAAGCTCAAGACG ACTGAGCAACTCTTTACCGAGCAGCAATCCCTACAGCGGAACCACAATGCCTTGCGCAGCCGCTTTCCGCCGCCC GACATGGCTGCCATGGGCCAGGAGCTTGTTTCTCTGCACAGACGCATCGCCATTGTCGCTGTCTCTGTCGCTGCC CTTGTAGCCTTGGCCGCCAGCTTTGTCGTTCGCTGCTCCAACCTGACGGCCTGGCTTGGGCTTGCCGTGGCTGCC GTGGCACTCATTGCTGGTGTTCAAGACTACGCCTCGGATCAAGTCCTTTCTACCTTTAAAGACGAGATTTGGGAG TCTCAGCGTCGACAGGTAGAGTCAAGGTCGAGCAGCTACGAGGTTGAGCCGACGGTTTGGCTCAATTCCCTCCTT GGCTCCGTCTGGCCGCTAATCAACCCAGACCTCTTTGTGAGCCTCTCGGACACGCTCGAGGATGTTATGCAGGCC TCTCTTCCTCGCCTCGTCCGCATGGTTAGCGTCGAGGACATTGGCCAGGGCAGCGAGGCCATTCGCATCCTTGGC ATTCGCTGGCTGCCCACTGGCGCCGCCGCAAAGACGGTTACGCGCGACGGCAAGCTATCGTCTGACGAGAGCTAC GACAATGATGTGGACCAGGAAAAGCCCAGGTCAGAAGAGGAAAAGGATGCAGAAAAGGCCTTTGCTGGCATGCGA GCAGAAGAAGGCGACTTTGTCAATATGGAAGTGGCTTTTGCCTACCGCTCTCGCCCTCGGTCACACCGTATCAAG GACCGCACCAAGAGCATGCACCTATATCTTGCCTTTTACTTGCCTGGAAACGTCAAGATTCCCGTATGGGTCGAT CTCAGGGGCATTGTGGGCGTCTTGAGGGTGCGGCTCCAGCTGACGCCCGATCCGCCCTTCTTCTCCCTCTGCACA TTGACCCTTCTCGGCCAGCCCAAGGTGGATCTGAGCTGCATCCCCCTCAGCCAGCGCGGCCTCAACATCATGGAC GTGCCCCTGATTAGTAACTTTGTGCAGTCGGCCGTCGATGCCGCTGTTGCCGACTATGTGGCTCCCAAGAGCCTC ACGCTCGATCTCAAGGACATGCTCGCTGGCGATGACTTCAAAAAGGACACAGTGTCGACGGGCGTCCTCATGGTC AATATCAAGCGCGGCTACGACTTCAAAATGGGCGACACTGCTATTCCCCTTATTAGAGACGGCAGCTCTGATCCC TATGTCTCTGTTGGCTGGGCCAAGTTTGGCAAGGTGCTTTGGAGCACGCGGGTGCTGGAATGCGAAATGGAGCCC TACTGGGACGAAACCTGCTTTGTCCTTGTCACGCCCGAAGAGCTCAACATTGATGAGCGCTTGCGGGTACAGCTC TGGGATTCGGACCGCTTCACCGCCGACGATGACTTGGGCCGCATCGAGGTGCCCTTGGCTGAGCTCTTGACGGAC CATCGCTCACGGGCCAAGATGTGGGAGCGTGTGGATGGCTTCCGCGCCCTCAGTGCAGGAGACAATATGCCTGGC AAGCTGGAGTGGAGTGTTGGCTATTTTGCAAAGACGGCCTTGCAGCAGTGCCAGCTGGACCTTCAGACGCATGAT TGCAAGGTGCGGACCATGCAACAGCTGCAGGTCAAGGTGGACAAGAGCTGTGAGCGGAAACTACGGGAAATAGTA GTCAAGCAGGGCCACGAAGAGGATGACGAGGCCGAAGTGGAGCGTCAGAGAGCCCTGGAGCTCAAGACAGAACAA GACGCCATCATCATTTCTGCGCCGCCGCCGGATGGCTACCCCAGCGGACTGCTTAGTCTGCAGATTCACAACATC ACGGGGCTCGAGCTTGACAAGTTGAGCAAGCGCCAGGTGGAAGACGAGGAAGAGGCCAGCGACGAAGAGGAGGCC GGGGACAGTTTGCCGAGTGCATACTGCACCGTGATTATCAACCACAGCAAGACGTTCAAGACTCGCATCAAGCCG CAGAATGCCAAGCCCTTTTTCAATGCTGGCTGCGAACGCTTCATCCGCGACTGGCGTGACTGCGAGGTGTTTGTC TCGGTGCGGGATGCCAGGCTGCATGAGGAGAATCCCTTGCTTGGCATTGTGCATCTACCGCTGAGCCACGTGCTC CGGGAGCGCTCACAGGTGATGGGGTTTTGGCCCCTGTCGGGCGGCATCGGGCACGGGCGCATCAGGCTGTCCCTG GTGTGGCGCAGCATCAATCTACAGGTGCCGCGCAACATGCTGGGCTGGAGTTATGGGACTTTGGACGTGGAGCCT GTGGCGACGAGCTCCGACTGCCCAGCGCAGCTCTCGTCGTGCCAGCTTAAGCTCAAGACGAATATCAGCATGGGC AAACTTTACGCGCACCAAGGCGGCGAGGGCAAGGCGGAGTGGAGGACCAAGCGGGAGCAGAATGTCAGTCTGGCT GTCAAGAAGCGCTATAGCAGCTGCATGTCTGTGTCGTTTCGGAACAAGAAGGGGCTTTTTGGAGACAAGGTTGCG TCGTTTTGCGTCATGTGGCTCAAGGACATTGCGGATGAGGAAGAGCAGGAGCTTGAGCTACCCATTTGGAAGGGA GATTTTGAGCGGGCCACGGCTTGCTGTCTGAAGGAGTGTGGCGAGCGAGTGGGCACACTGAAGCTCAAGGTGACC TTTTTGGCTGGCATGGGAAATGCCCACGCACGCTGGGCCTCTCGCAACCAAGACTTGCGCGATGTGATTGAGGTG ATTGAAACGGCACGAGACAACCTAGACGGAGACGAGATGGAAAAAGCGGCGGGCATTGGCGATGAGGATGCTTCG AGCGACAGCGACAGCTCGAGCGGCGAAAAGGACGAGGCGGATGGCAAGAGCCTCAAGGAAAAGCAGAGCACATTG GAGCAGATTCGCGACTATCGTCGCCGAGACAAGGCGCTGCATCGGCAACATCGGGGCATTATGCAGTGGAAGATT CCTCGAACAGCCAAATGGGTCAAGAACAAGTGGGGGCGGGTAGAAGACGGCGTGACGGGATTTTTCGAGCATGGC TCCCGACAGGCGGGCATTGAGACGGAGGTGTAG
Transcript	>OphauB2\|4465 ATGTCGGCCAAGGATGACGCCGACGATGTGAAGCGGTACCAAGCCCCCTACAGTGCCCAGCGGCCCATTCCCACC ATTTCCCGCTACCGAGAGATCAAGGCAGCACGCCGACGCGAGGCTGCATTCCGGCGGCAAGAGGATGGCGACGAC GACGACCAAACAGCACTGCTGCCTTCTTGGGCCCAGAATAATCAGCCTCTAGGCCGCTCCCGGAGCCAGTCTCGG ACAAGTCTGCAATCACAGACGGACGTGCCCACAGCCGACACCAAGAGTGAGCTCTCGACACTTGAGGATACGTCG CAGGTCGACGCCGCAGCAACAGATGTCAAGCAGAGGCGCAAGCGGCTCAAGTCGAGCTCCAGACACAAGGAGCGT GCCCAGCGCGAGGTTACCGATCCCGTCACCCATTTGCCCGTCACCATTCAAGACTTCACCGACGAGGCCCTCGAG GCTCTCGACTATAACCATGCGGCCCCCGGCTCCACGCCAGAAACCGCCACGGGTCGCGATGCCAAGCTCAAGACG ACTGAGCAACTCTTTACCGAGCAGCAATCCCTACAGCGGAACCACAATGCCTTGCGCAGCCGCTTTCCGCCGCCC GACATGGCTGCCATGGGCCAGGAGCTTGTTTCTCTGCACAGACGCATCGCCATTGTCGCTGTCTCTGTCGCTGCC CTTGTAGCCTTGGCCGCCAGCTTTGTCGTTCGCTGCTCCAACCTGACGGCCTGGCTTGGGCTTGCCGTGGCTGCC GTGGCACTCATTGCTGGTGTTCAAGACTACGCCTCGGATCAAGTCCTTTCTACCTTTAAAGACGAGATTTGGGAG TCTCAGCGTCGACAGGTAGAGTCAAGGTCGAGCAGCTACGAGGTTGAGCCGACGGTTTGGCTCAATTCCCTCCTT GGCTCCGTCTGGCCGCTAATCAACCCAGACCTCTTTGTGAGCCTCTCGGACACGCTCGAGGATGTTATGCAGGCC TCTCTTCCTCGCCTCGTCCGCATGGTTAGCGTCGAGGACATTGGCCAGGGCAGCGAGGCCATTCGCATCCTTGGC ATTCGCTGGCTGCCCACTGGCGCCGCCGCAAAGACGGTTACGCGCGACGGCAAGCTATCGTCTGACGAGAGCTAC GACAATGATGTGGACCAGGAAAAGCCCAGGTCAGAAGAGGAAAAGGATGCAGAAAAGGCCTTTGCTGGCATGCGA GCAGAAGAAGGCGACTTTGTCAATATGGAAGTGGCTTTTGCCTACCGCTCTCGCCCTCGGTCACACCGTATCAAG GACCGCACCAAGAGCATGCACCTATATCTTGCCTTTTACTTGCCTGGAAACGTCAAGATTCCCGTATGGGTCGAT CTCAGGGGCATTGTGGGCGTCTTGAGGGTGCGGCTCCAGCTGACGCCCGATCCGCCCTTCTTCTCCCTCTGCACA TTGACCCTTCTCGGCCAGCCCAAGGTGGATCTGAGCTGCATCCCCCTCAGCCAGCGCGGCCTCAACATCATGGAC GTGCCCCTGATTAGTAACTTTGTGCAGTCGGCCGTCGATGCCGCTGTTGCCGACTATGTGGCTCCCAAGAGCCTC ACGCTCGATCTCAAGGACATGCTCGCTGGCGATGACTTCAAAAAGGACACAGTGTCGACGGGCGTCCTCATGGTC AATATCAAGCGCGGCTACGACTTCAAAATGGGCGACACTGCTATTCCCCTTATTAGAGACGGCAGCTCTGATCCC TATGTCTCTGTTGGCTGGGCCAAGTTTGGCAAGGTGCTTTGGAGCACGCGGGTGCTGGAATGCGAAATGGAGCCC TACTGGGACGAAACCTGCTTTGTCCTTGTCACGCCCGAAGAGCTCAACATTGATGAGCGCTTGCGGGTACAGCTC TGGGATTCGGACCGCTTCACCGCCGACGATGACTTGGGCCGCATCGAGGTGCCCTTGGCTGAGCTCTTGACGGAC CATCGCTCACGGGCCAAGATGTGGGAGCGTGTGGATGGCTTCCGCGCCCTCAGTGCAGGAGACAATATGCCTGGC AAGCTGGAGTGGAGTGTTGGCTATTTTGCAAAGACGGCCTTGCAGCAGTGCCAGCTGGACCTTCAGACGCATGAT TGCAAGGTGCGGACCATGCAACAGCTGCAGGTCAAGGTGGACAAGAGCTGTGAGCGGAAACTACGGGAAATAGTA GTCAAGCAGGGCCACGAAGAGGATGACGAGGCCGAAGTGGAGCGTCAGAGAGCCCTGGAGCTCAAGACAGAACAA GACGCCATCATCATTTCTGCGCCGCCGCCGGATGGCTACCCCAGCGGACTGCTTAGTCTGCAGATTCACAACATC ACGGGGCTCGAGCTTGACAAGTTGAGCAAGCGCCAGGTGGAAGACGAGGAAGAGGCCAGCGACGAAGAGGAGGCC GGGGACAGTTTGCCGAGTGCATACTGCACCGTGATTATCAACCACAGCAAGACGTTCAAGACTCGCATCAAGCCG CAGAATGCCAAGCCCTTTTTCAATGCTGGCTGCGAACGCTTCATCCGCGACTGGCGTGACTGCGAGGTGTTTGTC TCGGTGCGGGATGCCAGGCTGCATGAGGAGAATCCCTTGCTTGGCATTGTGCATCTACCGCTGAGCCACGTGCTC CGGGAGCGCTCACAGGTGATGGGGTTTTGGCCCCTGTCGGGCGGCATCGGGCACGGGCGCATCAGGCTGTCCCTG GTGTGGCGCAGCATCAATCTACAGGTGCCGCGCAACATGCTGGGCTGGAGTTATGGGACTTTGGACGTGGAGCCT GTGGCGACGAGCTCCGACTGCCCAGCGCAGCTCTCGTCGTGCCAGCTTAAGCTCAAGACGAATATCAGCATGGGC AAACTTTACGCGCACCAAGGCGGCGAGGGCAAGGCGGAGTGGAGGACCAAGCGGGAGCAGAATGTCAGTCTGGCT GTCAAGAAGCGCTATAGCAGCTGCATGTCTGTGTCGTTTCGGAACAAGAAGGGGCTTTTTGGAGACAAGGTTGCG TCGTTTTGCGTCATGTGGCTCAAGGACATTGCGGATGAGGAAGAGCAGGAGCTTGAGCTACCCATTTGGAAGGGA GATTTTGAGCGGGCCACGGCTTGCTGTCTGAAGGAGTGTGGCGAGCGAGTGGGCACACTGAAGCTCAAGGTGACC TTTTTGGCTGGCATGGGAAATGCCCACGCACGCTGGGCCTCTCGCAACCAAGACTTGCGCGATGTGATTGAGGTG ATTGAAACGGCACGAGACAACCTAGACGGAGACGAGATGGAAAAAGCGGCGGGCATTGGCGATGAGGATGCTTCG AGCGACAGCGACAGCTCGAGCGGCGAAAAGGACGAGGCGGATGGCAAGAGCCTCAAGGAAAAGCAGAGCACATTG GAGCAGATTCGCGACTATCGTCGCCGAGACAAGGCGCTGCATCGGCAACATCGGGGCATTATGCAGTGGAAGATT CCTCGAACAGCCAAATGGGTCAAGAACAAGTGGGGGCGGGTAGAAGACGGCGTGACGGGATTTTTCGAGCATGGC TCCCGACAGGCGGGCATTGAGACGGAGGTGTAG
Gene	>OphauB2\|4465 ATGTCGGCCAAGGATGACGCCGACGATGTGAAGCGGTACCAAGCCCCCTACAGTGCCCAGCGGCCCATTCCCACC ATTTCCCGCTACCGAGAGATCAAGGCAGCACGCCGACGCGAGGCTGCATTCCGGCGGCAAGAGGATGGCGACGAC GACGACCAAACAGCACTGCTGCCTTCTTGGGCCCAGAATAATCAGCCTCTAGGCCGCTCCCGGAGCCAGTCTCGG ACAAGTCTGCAATCACAGACGGACGTGCCCACAGCCGACACCAAGAGTGAGCTCTCGACACTTGAGGATACGTCG CAGGTCGACGCCGCAGCAACAGATGTCAAGCAGAGGCGCAAGCGGCTCAAGTCGAGCTCCAGACACAAGGAGCGT GCCCAGCGCGAGGTTACCGATCCCGTCACCCATTTGCCCGTCACCATTCAAGACTTCACCGACGAGGCCCTCGAG GCTCTCGACTATAACCATGCGGCCCCCGGCTCCACGCCAGAAACCGCCACGGGTCGCGATGCCAAGCTCAAGACG ACTGAGCAACTCTTTACCGAGCAGCAATCCCTACAGCGGAACCACAATGCCTTGCGCAGCCGCTTTCCGCCGCCC GACATGGCTGCCATGGGCCAGGAGCTTGTTTCTCTGCACAGACGCATCGCCATTGTCGCTGTCTCTGTCGCTGCC CTTGTAGCCTTGGCCGCCAGCTTTGTCGTTCGCTGCTCCAACCTGACGGCCTGGCTTGGGCTTGCCGTGGCTGCC GTGGCACTCATTGCTGGTGTTCAAGACTACGCCTCGGATCAAGTCCTTTCTACCTTTAAAGACGAGATTTGGGAG TCTCAGCGTCGACAGGTAGAGTCAAGGTCGAGCAGCTACGAGGTTGAGCCGACGGTTTGGCTCAATTCCCTCCTT GGCTCCGTCTGGCCGCTAATCAACCCAGACCTCTTTGTGAGCCTCTCGGACACGCTCGAGGATGTTATGCAGGCC TCTCTTCCTCGCCTCGTCCGCATGGTTAGCGTCGAGGACATTGGCCAGGGCAGCGAGGCCATTCGCATCCTTGGC ATTCGCTGGCTGCCCACTGGCGCCGCCGCAAAGACGGTTACGCGCGACGGCAAGCTATCGTCTGACGAGAGCTAC GACAATGATGTGGACCAGGAAAAGCCCAGGTCAGAAGAGGAAAAGGATGCAGAAAAGGCCTTTGCTGGCATGCGA GCAGAAGAAGGCGACTTTGTCAATATGGAAGTGGCTTTTGCCTACCGCTCTCGCCCTCGGTCACACCGTATCAAG GACCGCACCAAGAGCATGCACCTATATCTTGCCTTTTACTTGCCTGGAAACGTCAAGATTCCCGTATGGGTCGAT CTCAGGGGCATTGTGGGCGTCTTGAGGGTGCGGCTCCAGCTGACGCCCGATCCGCCCTTCTTCTCCCTCTGCACA TTGACCCTTCTCGGCCAGCCCAAGGTGGATCTGAGCTGCATCCCCCTCAGCCAGCGCGGCCTCAACATCATGGAC GTGCCCCTGATTAGTAACTTTGTGCAGTCGGCCGTCGATGCCGCTGTTGCCGACTATGTGGCTCCCAAGAGCCTC ACGCTCGATCTCAAGGACATGCTCGCTGGCGATGACTTCAAAAAGGACACAGTGTCGACGGGCGTCCTCATGGTC AATATCAAGCGCGGCTACGACTTCAAAATGGGCGACACTGCTATTCCCCTTATTAGAGACGGCAGCTCTGATCCC TATGTCTCTGTTGGCTGGGCCAAGTTTGGCAAGGTGCTTTGGAGCACGCGGGTGCTGGAATGCGAAATGGAGCCC TACTGGGACGAAACCTGCTTTGTCCTTGTCACGCCCGAAGAGCTCAACATTGATGAGCGCTTGCGGGTACAGCTC TGGGATTCGGACCGCTTCACCGCCGACGATGACTTGGGCCGCATCGAGGTGCCCTTGGCTGAGCTCTTGACGGAC CATCGCTCACGGGCCAAGATGTGGGAGCGTGTGGATGGCTTCCGCGCCCTCAGTGCAGGAGACAATATGCCTGGC AAGCTGGAGTGGAGTGTTGGCTATTTTGCAAAGACGGCCTTGCAGCAGTGCCAGCTGGACCTTCAGACGCATGAT TGCAAGGTGCGGACCATGCAACAGCTGCAGGTCAAGGTGGACAAGAGCTGTGAGCGGAAACTACGGGAAATAGTA GTCAAGCAGGGCCACGAAGAGGATGACGAGGCCGAAGTGGAGCGTCAGAGAGCCCTGGAGCTCAAGACAGAACAA GACGCCATCATCATTTCTGCGCCGCCGCCGGATGGCTACCCCAGCGGACTGCTTAGTCTGCAGATTCACAACATC ACGGGGCTCGAGCTTGACAAGTTGAGCAAGCGCCAGGTGGAAGACGAGGAAGAGGCCAGCGACGAAGAGGAGGCC GGGGACAGTTTGCCGAGTGCATACTGCACCGTGATTATCAACCACAGCAAGACGTTCAAGACTCGCATCAAGCCG CAGAATGCCAAGCCCTTTTTCAATGCTGGCTGCGAACGCTTCATCCGCGACTGGCGTGACTGCGAGGTGTTTGTC TCGGTGCGGGATGCCAGGCTGCATGAGGAGAATCCCTTGCTTGGCATTGTGCATCTACCGCTGAGCCACGTGCTC CGGGAGCGCTCACAGGTGATGGGGTTTTGGCCCCTGTCGGGCGGCATCGGGCACGGGCGCATCAGGCTGTCCCTG GTGTGGCGCAGCATCAATCTACAGGTGCCGCGCAACATGCTGGGCTGGAGTTATGGGACTTTGGACGTGGAGCCT GTGGCGACGAGCTCCGACTGCCCAGCGCAGCTCTCGTCGTGCCAGCTTAAGCTCAAGACGAATATCAGCATGGGC AAACTTTACGCGCACCAAGGCGGCGAGGGCAAGGCGGAGTGGAGGACCAAGCGGGAGCAGAATGTCAGTCTGGCT GTCAAGAAGCGCTATAGCAGCTGCATGTCTGTGTCGTTTCGGAACAAGAAGGGGCTTTTTGGAGACAAGGTTGCG TCGTTTTGCGTCATGTGGCTCAAGGACATTGCGGATGAGGAAGAGCAGGAGCTTGAGCTACCCATTTGGAAGGGA GATTTTGAGCGGGCCACGGCTTGCTGTCTGAAGGAGTGTGGCGAGCGAGTGGGCACACTGAAGCTCAAGGTGACC TTTTTGGCTGGCATGGTGAGTTTTGTGTGTAGTCTTGACGAGGGTGCAGGCAACATGGCAAGCGGGCTAACGAGG GCTTTGTGTTTTTTGTGCAAAGGGAAATGCCCACGCACGCTGGGCCTCTCGCAACCAAGACTTGCGCGATGTGAT TGAGGTGATTGAAACGGCACGAGACAACCTAGACGGAGACGAGATGGAAAAAGCGGCGGGCATTGGCGATGAGGA TGCTTCGAGCGACAGCGACAGCTCGAGCGGCGAAAAGGACGAGGCGGATGGCAAGAGCCTCAAGGAAAAGCAGAG CACATTGGAGCAGATTCGCGACTATCGTCGCCGAGACAAGGCGCTGCATCGGCAACATCGGGGCATTATGCAGTG GAAGGTGAGGGAGAAGCATTTTTGATTGGGAGCTGTTTTGTCTCGACAAGGCGTCTCGACTGACGCATTGCTGCA GATTCCTCGAACAGCCAAATGGGTCAAGAACAAGTGGGGGCGGGTAGAAGACGGCGTGACGGGATTTTTCGAGCA TGGCTCCCGACAGGCGGGCATTGAGACGGAGGTGTAG

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