Fungal Genomics

at Utrecht University

General Properties

Protein ID	OphauB2\|4037
Gene name
Location	Contig_26:144342..147892
Strand	+
Gene length (bp)	3550
Transcript length (bp)	3201
Coding sequence length (bp)	3201
Protein length (aa)	1067

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF07993	NAD_binding_4	Male sterility protein	3.0E-25	705	942
PF00501	AMP-binding	AMP-binding enzyme	1.5E-22	43	355
PF01370	Epimerase	NAD dependent epimerase/dehydratase family	1.4E-04	701	897

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q70LM4\|LGRD_BREPA	Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis GN=lgrD PE=1 SV=1	410	994	5.0E-23
sp\|A1CLY8\|CCSA_ASPCL	Polyketide synthase-nonribosomal peptide synthetase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=ccsA PE=3 SV=1	553	991	2.0E-14
sp\|Q6FMI5\|LYS2_CANGA	L-2-aminoadipate reductase large subunit OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=LYS2 PE=3 SV=1	594	951	5.0E-10
sp\|Q55CN6\|PKS3_DICDI	Probable polyketide synthase 3 OS=Dictyostelium discoideum GN=pks3 PE=3 SV=1	701	1001	9.0E-10
sp\|O74298\|LYS2_PENCH	L-2-aminoadipate reductase large subunit OS=Penicillium chrysogenum GN=lys2 PE=3 SV=1	635	994	3.0E-09

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q70LM4\|LGRD_BREPA	Linear gramicidin synthase subunit D OS=Brevibacillus parabrevis GN=lgrD PE=1 SV=1	410	994	5.0E-23
sp\|A1CLY8\|CCSA_ASPCL	Polyketide synthase-nonribosomal peptide synthetase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=ccsA PE=3 SV=1	553	991	2.0E-14
sp\|Q6FMI5\|LYS2_CANGA	L-2-aminoadipate reductase large subunit OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=LYS2 PE=3 SV=1	594	951	5.0E-10
sp\|Q55CN6\|PKS3_DICDI	Probable polyketide synthase 3 OS=Dictyostelium discoideum GN=pks3 PE=3 SV=1	701	1001	9.0E-10
sp\|O74298\|LYS2_PENCH	L-2-aminoadipate reductase large subunit OS=Penicillium chrysogenum GN=lys2 PE=3 SV=1	635	994	3.0E-09
sp\|Q75BB3\|LYS2_ASHGO	L-2-aminoadipate reductase large subunit OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=LYS2 PE=3 SV=2	579	994	7.0E-09
sp\|P07702\|LYS2_YEAST	L-2-aminoadipate reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS2 PE=1 SV=2	406	948	7.0E-09
sp\|Q558Y6\|PKS14_DICDI	Probable polyketide synthase 14 OS=Dictyostelium discoideum GN=pks14 PE=3 SV=2	699	1000	1.0E-08
sp\|Q54FC8\|PKS39_DICDI	Probable polyketide synthase 39 OS=Dictyostelium discoideum GN=pks39 PE=3 SV=1	703	1001	2.0E-08
sp\|P37693\|HETM_NOSS1	Polyketide synthase HetM OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=hetM PE=3 SV=1	590	997	5.0E-08
sp\|Q54TW0\|PKS18_DICDI	Probable polyketide synthase 18 OS=Dictyostelium discoideum GN=pks18 PE=2 SV=1	701	1001	7.0E-08
sp\|Q54FP8\|PKS32_DICDI	Probable polyketide synthase 32 OS=Dictyostelium discoideum GN=pks32 PE=3 SV=1	703	1007	1.0E-07
sp\|Q54FN2\|PKS34_DICDI	Probable polyketide synthase 34 OS=Dictyostelium discoideum GN=pks34 PE=3 SV=1	703	1001	1.0E-07
sp\|Q54FQ2\|PKS30_DICDI	Probable polyketide synthase 30 OS=Dictyostelium discoideum GN=pks30 PE=3 SV=1	703	1007	1.0E-07
sp\|Q54FD2\|PKS38_DICDI	Probable polyketide synthase 38 OS=Dictyostelium discoideum GN=pks38 PE=3 SV=1	766	1001	1.0E-07
sp\|Q960W6\|FACR3_DROME	Putative fatty acyl-CoA reductase CG8306 OS=Drosophila melanogaster GN=CG8306 PE=2 SV=1	700	942	2.0E-06

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 70	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>OphauB2\|4037 MASLPPHDYGKRLLPQVVDWYARHDAGKLYASLPRSATDLAAGFQDISMAMLAAMVNRMSWHFEAVLGRGSLESI AYLGPADIRYAVLFLAAVKAGYQMLFISPRNQSAQNQRMLVMSSCKALLYAQELCAAAEPLAARLPALVVQQAPL LDDLVATPLATQHYPYDKTFDEARDEPCLILHSSGSTGMNGLTSVCVCVFCACDPKLVTMTHGTFSVVDNDRTMA VPEGRVAQNAARFDFERGGKFYSCFPPYHLAGVHAFIDLPIFYHGATVVFGPVNLPPSGYLLSEIVKMQHLRAFY VPPFIIEQWAAEPCSMQQAPTLDFVLYGGGPLSPQTGDRLSRATSVCQMYGSLELGQIQLLVPERAEWAHMELNP HEEADMQPLGDGTYEMVLHQHEKFATRRSLWHNFPGVQTWRTGDLFLPHPSKQGLWRFHSRVDDLVVLSSSHKLR PLEMETIIQGHELVAGAIIVGQGKPEPLLIVEPREGAFNGHEPRFIDAIWTAVQEANEIAPSYAQIKRSNVLVSK PERPFIRAPKGSIVRKLTIAAYADDIEAAYAADAPPSKATMPAQGMDGFVLPGLKQMVRAHVEDELPGVTISDAD SLFARGLDSMGCARLSRSLQKTLAAQGSTDGSCALTMRMIYKYPSIEGLATVVLNIVFNRTLPDVSIGSDTKMMK SALETLTQNLPARKATRAAPTEALTIVLIGPRGSLGPHIVRQLLQSRRVAKIYSLNRGQHGRERMRALVKQRGLA LDVDDARLCFMPFELGKPHLGLSDEDYALVLRSANLVIHNAWKIDFNWTIEQYQADYLPSVRHLVDFSAESPLSP RIVFISSISSVQEWAAVFPTPVTEEPLESFQVASPLGYGQSKHVSERILTAASAISGTPVTILRVGQIAGSTTGS GGAWTPDEWVPSLASISRSLNKVPVDIPPIDWVPANLAAQAIAELALNDSCPPLRVFNIVNPKLSPWFTFVKALQ SRLGDSVQAVTLAEWVSALVGTDPKSMSDAAATSSTKLLPFFQHLAQTAAKGVALQPRFETGKAMGASETMAGMA AIDERVIDIWLQQWDI*
Coding	>OphauB2\|4037 ATGGCCTCGTTGCCGCCTCACGACTACGGCAAGCGCCTCTTGCCCCAAGTGGTCGACTGGTATGCCCGCCACGAT GCGGGAAAGCTCTACGCCAGTCTGCCCAGGTCGGCAACAGATCTGGCAGCCGGCTTCCAGGACATTTCCATGGCC ATGCTGGCCGCCATGGTGAACCGCATGTCGTGGCATTTCGAAGCTGTGCTTGGCCGGGGCAGCCTCGAGTCTATT GCCTATCTCGGCCCGGCGGATATTCGATACGCCGTCTTGTTTCTCGCGGCCGTCAAGGCGGGATACCAGATGCTC TTCATCTCCCCCCGGAACCAATCAGCACAGAACCAGCGCATGCTCGTCATGTCGTCATGCAAGGCGCTTCTTTAC GCCCAGGAGCTCTGCGCGGCTGCTGAGCCGCTCGCCGCTCGCCTCCCCGCGCTGGTGGTGCAGCAGGCGCCGCTG CTGGACGACTTGGTGGCCACGCCGCTCGCCACGCAGCATTACCCCTACGACAAGACATTTGACGAGGCTCGCGAT GAGCCTTGTCTGATTCTGCACTCGTCGGGGTCGACAGGTATGAATGGCTTGACAAGCGTGTGTGTGTGTGTGTTT TGCGCGTGTGATCCAAAGCTCGTGACAATGACGCACGGTACCTTTTCCGTGGTGGACAATGATCGCACCATGGCT GTTCCAGAGGGACGTGTGGCGCAAAATGCAGCGCGTTTCGACTTTGAGCGAGGGGGCAAGTTTTATTCTTGTTTT CCCCCCTATCATCTTGCCGGCGTCCACGCCTTCATCGACCTACCCATCTTCTACCATGGCGCCACCGTCGTCTTT GGCCCAGTCAACCTCCCCCCCAGCGGCTACCTCCTCTCTGAAATCGTCAAGATGCAGCACCTGCGCGCCTTTTAC GTCCCGCCCTTCATCATTGAGCAATGGGCCGCCGAGCCGTGCTCCATGCAGCAAGCTCCAACCCTCGACTTTGTC CTCTATGGCGGCGGGCCCCTCTCCCCCCAAACAGGCGACAGACTGAGCCGCGCCACCAGCGTCTGCCAAATGTAC GGCTCGCTTGAACTCGGCCAGATCCAGCTGCTGGTGCCGGAGCGCGCCGAGTGGGCGCACATGGAGCTGAATCCG CATGAAGAGGCCGACATGCAGCCCCTGGGCGACGGCACGTATGAAATGGTGCTGCACCAGCATGAAAAGTTTGCC ACGCGCCGCAGCCTGTGGCACAACTTCCCTGGCGTGCAGACGTGGCGCACAGGAGACTTGTTTCTGCCCCATCCG TCAAAACAGGGGCTGTGGCGCTTCCACTCGCGAGTCGACGACTTGGTGGTGCTGTCGAGCAGCCATAAGCTCCGC CCGCTCGAGATGGAGACGATTATCCAGGGCCATGAGCTTGTTGCCGGAGCTATTATTGTCGGGCAGGGCAAGCCG GAGCCGCTGCTCATTGTCGAGCCGAGAGAGGGCGCCTTCAACGGCCACGAGCCGCGCTTCATTGATGCTATTTGG ACAGCGGTGCAGGAAGCAAACGAAATTGCACCCAGCTACGCGCAGATTAAGCGCAGCAATGTCCTCGTCTCCAAG CCTGAGCGGCCCTTTATCCGCGCCCCCAAAGGCAGCATTGTTCGCAAACTCACCATTGCGGCCTATGCCGACGAC ATTGAAGCTGCCTACGCCGCCGACGCTCCGCCAAGCAAGGCGACAATGCCGGCACAGGGCATGGATGGCTTCGTC TTGCCCGGGCTGAAGCAAATGGTGCGCGCCCACGTTGAAGACGAGCTTCCCGGCGTCACCATTTCAGACGCGGAT AGCTTGTTTGCCCGCGGCCTCGACTCCATGGGCTGCGCGCGTCTGAGCCGGAGCTTGCAAAAGACGCTGGCGGCT CAGGGCAGCACCGACGGAAGCTGTGCCTTGACGATGCGCATGATTTACAAGTATCCCTCCATAGAGGGCCTGGCA ACGGTGGTGCTAAACATTGTCTTTAACCGCACGCTGCCCGACGTGTCGATTGGAAGCGACACCAAGATGATGAAG AGCGCGCTCGAGACGCTCACGCAGAACCTGCCCGCCAGAAAAGCAACACGTGCTGCTCCTACCGAGGCCCTGACT ATTGTCTTGATTGGGCCGCGTGGGTCGCTGGGGCCTCATATTGTGCGCCAGCTGCTGCAGAGTCGTCGAGTGGCC AAGATTTACAGTCTGAATAGGGGGCAGCATGGCCGAGAGAGGATGCGCGCCCTCGTCAAGCAGCGAGGCTTGGCT CTCGACGTGGACGATGCTCGTCTGTGTTTTATGCCGTTTGAGCTTGGCAAACCCCATCTCGGTCTCAGTGACGAG GATTACGCTCTCGTGCTGCGCAGCGCCAACCTCGTCATTCACAATGCGTGGAAAATCGACTTCAACTGGACCATT GAGCAGTACCAGGCCGACTATCTGCCCAGCGTGCGCCATCTCGTCGACTTTTCCGCCGAGAGCCCTCTCTCGCCT CGCATCGTCTTCATCTCTTCCATTTCTTCTGTTCAGGAATGGGCCGCTGTTTTCCCCACCCCCGTGACTGAAGAG CCTCTTGAATCCTTCCAGGTCGCCTCGCCTCTGGGCTACGGCCAGTCCAAGCACGTTTCTGAGCGCATCCTCACG GCAGCGAGTGCCATTTCCGGCACCCCAGTCACCATTCTCCGCGTCGGCCAGATTGCCGGCTCGACTACGGGAAGC GGCGGCGCCTGGACTCCTGATGAATGGGTTCCCTCGCTCGCCTCCATTTCTCGCTCCCTCAACAAAGTCCCCGTC GATATTCCGCCCATTGACTGGGTTCCCGCCAATCTCGCCGCCCAAGCCATTGCTGAGCTCGCTCTCAACGACTCT TGTCCTCCTCTCCGCGTTTTCAACATTGTCAATCCAAAGCTCTCTCCTTGGTTTACCTTTGTTAAAGCCCTGCAG AGCCGTCTGGGAGACTCTGTGCAGGCGGTTACGCTGGCAGAATGGGTATCTGCCCTTGTGGGCACAGATCCAAAG TCCATGTCGGATGCGGCTGCCACGTCTTCGACCAAGCTGCTTCCCTTTTTCCAGCACTTGGCGCAGACGGCGGCA AAGGGCGTTGCGCTGCAGCCGAGGTTTGAGACGGGCAAGGCCATGGGGGCTAGTGAGACCATGGCTGGCATGGCG GCCATTGATGAGCGTGTTATTGACATTTGGCTTCAGCAGTGGGATATTTGA
Transcript	>OphauB2\|4037 ATGGCCTCGTTGCCGCCTCACGACTACGGCAAGCGCCTCTTGCCCCAAGTGGTCGACTGGTATGCCCGCCACGAT GCGGGAAAGCTCTACGCCAGTCTGCCCAGGTCGGCAACAGATCTGGCAGCCGGCTTCCAGGACATTTCCATGGCC ATGCTGGCCGCCATGGTGAACCGCATGTCGTGGCATTTCGAAGCTGTGCTTGGCCGGGGCAGCCTCGAGTCTATT GCCTATCTCGGCCCGGCGGATATTCGATACGCCGTCTTGTTTCTCGCGGCCGTCAAGGCGGGATACCAGATGCTC TTCATCTCCCCCCGGAACCAATCAGCACAGAACCAGCGCATGCTCGTCATGTCGTCATGCAAGGCGCTTCTTTAC GCCCAGGAGCTCTGCGCGGCTGCTGAGCCGCTCGCCGCTCGCCTCCCCGCGCTGGTGGTGCAGCAGGCGCCGCTG CTGGACGACTTGGTGGCCACGCCGCTCGCCACGCAGCATTACCCCTACGACAAGACATTTGACGAGGCTCGCGAT GAGCCTTGTCTGATTCTGCACTCGTCGGGGTCGACAGGTATGAATGGCTTGACAAGCGTGTGTGTGTGTGTGTTT TGCGCGTGTGATCCAAAGCTCGTGACAATGACGCACGGTACCTTTTCCGTGGTGGACAATGATCGCACCATGGCT GTTCCAGAGGGACGTGTGGCGCAAAATGCAGCGCGTTTCGACTTTGAGCGAGGGGGCAAGTTTTATTCTTGTTTT CCCCCCTATCATCTTGCCGGCGTCCACGCCTTCATCGACCTACCCATCTTCTACCATGGCGCCACCGTCGTCTTT GGCCCAGTCAACCTCCCCCCCAGCGGCTACCTCCTCTCTGAAATCGTCAAGATGCAGCACCTGCGCGCCTTTTAC GTCCCGCCCTTCATCATTGAGCAATGGGCCGCCGAGCCGTGCTCCATGCAGCAAGCTCCAACCCTCGACTTTGTC CTCTATGGCGGCGGGCCCCTCTCCCCCCAAACAGGCGACAGACTGAGCCGCGCCACCAGCGTCTGCCAAATGTAC GGCTCGCTTGAACTCGGCCAGATCCAGCTGCTGGTGCCGGAGCGCGCCGAGTGGGCGCACATGGAGCTGAATCCG CATGAAGAGGCCGACATGCAGCCCCTGGGCGACGGCACGTATGAAATGGTGCTGCACCAGCATGAAAAGTTTGCC ACGCGCCGCAGCCTGTGGCACAACTTCCCTGGCGTGCAGACGTGGCGCACAGGAGACTTGTTTCTGCCCCATCCG TCAAAACAGGGGCTGTGGCGCTTCCACTCGCGAGTCGACGACTTGGTGGTGCTGTCGAGCAGCCATAAGCTCCGC CCGCTCGAGATGGAGACGATTATCCAGGGCCATGAGCTTGTTGCCGGAGCTATTATTGTCGGGCAGGGCAAGCCG GAGCCGCTGCTCATTGTCGAGCCGAGAGAGGGCGCCTTCAACGGCCACGAGCCGCGCTTCATTGATGCTATTTGG ACAGCGGTGCAGGAAGCAAACGAAATTGCACCCAGCTACGCGCAGATTAAGCGCAGCAATGTCCTCGTCTCCAAG CCTGAGCGGCCCTTTATCCGCGCCCCCAAAGGCAGCATTGTTCGCAAACTCACCATTGCGGCCTATGCCGACGAC ATTGAAGCTGCCTACGCCGCCGACGCTCCGCCAAGCAAGGCGACAATGCCGGCACAGGGCATGGATGGCTTCGTC TTGCCCGGGCTGAAGCAAATGGTGCGCGCCCACGTTGAAGACGAGCTTCCCGGCGTCACCATTTCAGACGCGGAT AGCTTGTTTGCCCGCGGCCTCGACTCCATGGGCTGCGCGCGTCTGAGCCGGAGCTTGCAAAAGACGCTGGCGGCT CAGGGCAGCACCGACGGAAGCTGTGCCTTGACGATGCGCATGATTTACAAGTATCCCTCCATAGAGGGCCTGGCA ACGGTGGTGCTAAACATTGTCTTTAACCGCACGCTGCCCGACGTGTCGATTGGAAGCGACACCAAGATGATGAAG AGCGCGCTCGAGACGCTCACGCAGAACCTGCCCGCCAGAAAAGCAACACGTGCTGCTCCTACCGAGGCCCTGACT ATTGTCTTGATTGGGCCGCGTGGGTCGCTGGGGCCTCATATTGTGCGCCAGCTGCTGCAGAGTCGTCGAGTGGCC AAGATTTACAGTCTGAATAGGGGGCAGCATGGCCGAGAGAGGATGCGCGCCCTCGTCAAGCAGCGAGGCTTGGCT CTCGACGTGGACGATGCTCGTCTGTGTTTTATGCCGTTTGAGCTTGGCAAACCCCATCTCGGTCTCAGTGACGAG GATTACGCTCTCGTGCTGCGCAGCGCCAACCTCGTCATTCACAATGCGTGGAAAATCGACTTCAACTGGACCATT GAGCAGTACCAGGCCGACTATCTGCCCAGCGTGCGCCATCTCGTCGACTTTTCCGCCGAGAGCCCTCTCTCGCCT CGCATCGTCTTCATCTCTTCCATTTCTTCTGTTCAGGAATGGGCCGCTGTTTTCCCCACCCCCGTGACTGAAGAG CCTCTTGAATCCTTCCAGGTCGCCTCGCCTCTGGGCTACGGCCAGTCCAAGCACGTTTCTGAGCGCATCCTCACG GCAGCGAGTGCCATTTCCGGCACCCCAGTCACCATTCTCCGCGTCGGCCAGATTGCCGGCTCGACTACGGGAAGC GGCGGCGCCTGGACTCCTGATGAATGGGTTCCCTCGCTCGCCTCCATTTCTCGCTCCCTCAACAAAGTCCCCGTC GATATTCCGCCCATTGACTGGGTTCCCGCCAATCTCGCCGCCCAAGCCATTGCTGAGCTCGCTCTCAACGACTCT TGTCCTCCTCTCCGCGTTTTCAACATTGTCAATCCAAAGCTCTCTCCTTGGTTTACCTTTGTTAAAGCCCTGCAG AGCCGTCTGGGAGACTCTGTGCAGGCGGTTACGCTGGCAGAATGGGTATCTGCCCTTGTGGGCACAGATCCAAAG TCCATGTCGGATGCGGCTGCCACGTCTTCGACCAAGCTGCTTCCCTTTTTCCAGCACTTGGCGCAGACGGCGGCA AAGGGCGTTGCGCTGCAGCCGAGGTTTGAGACGGGCAAGGCCATGGGGGCTAGTGAGACCATGGCTGGCATGGCG GCCATTGATGAGCGTGTTATTGACATTTGGCTTCAGCAGTGGGATATTTGA
Gene	>OphauB2\|4037 ATGGCCTCGTTGCCGCCTCACGACTACGGCAAGCGCCTCTTGCCCCAAGTGGTCGACTGGTATGCCCGCCACGAT GCGGGAAAGCTCTACGCCAGTCTGCCCAGGTCGGCAACAGATCTGGCAGCCGGCTTCCAGGACATTTCCATGGCC ATGCTGGCCGCCATGGTGAACCGCATGTCGTGGCATTTCGAAGCTGTGCTTGGCCGGGGCAGCCTCGAGTCTATT GCCTATCTCGGCCCGGCGGATATTCGATACGCCGTCTTGTTTCTCGCGGCCGTCAAGGCGGGATACCAGGCACGT AGTCTCGTCATGTTTTTACCCCCCCCCCTGAAGAGAGCCTCATGATGTACAATCATCTACAAACCTGAAAGAAGG AAATCATTATTAAAAAAAAATAGATGAAACGAATAAAGACAAAAGAGACAAAAAGGGTGACGAGGGAAAAAAAAA AAAAAATCTCCGACTAACCTCGTCTCCTTAGATGCTCTTCATCTCCCCCCGGAACCAATCAGCACAGAACCAGCG CATGCTCGTCATGTCGTCATGCAAGGCGCTTCTTTACGCCCAGGAGCTCTGCGCGGCTGCTGAGCCGCTCGCCGC TCGCCTCCCCGCGCTGGTGGTGCAGCAGGCGCCGCTGCTGGACGACTTGGTGGCCACGCCGCTCGCCACGCAGCA TTACCCCTACGACAAGACATTTGACGAGGCTCGCGATGAGCCTTGTCTGATTCTGCACTCGTCGGGGTCGACAGG TATGAATGGCTTGACAAGCGTGTGTGTGTGTGTGTTTTGCGCGTGTGAGTGGGTTGTAGATGGGGCCTTTTTGTC TAATAGCCCTTGTGCCGCGCGTCTCAGGTGATCCAAAGCTCGTGACAATGACGCACGGTACCTTTTCCGTGGTGG ACAATGATCGCACCATGGCTGTTCCAGAGGGACGTGTGGCGCAAAATGCAGCGCGTTTCGACTTTGAGCGAGGGG GCAAGTTTTATTCTTGTTTTCCCCCCTATCATGTAAGTTTTGCCTAGCAGTCACTTCTTGTCTTTTCGTCGAGTC TTGCTTCAACTCTTGTCTTTTCTTCCTCTTCACCTCTTGCATATTGTCTGACAATCTATAGCTTGCCGGCGTCCA CGCCTTCATCGACCTACCCATCTTCTACCATGGCGCCACCGTCGTCTTTGGCCCAGTCAACCTCCCCCCCAGCGG CTACCTCCTCTCTGAAATCGTCAAGATGCAGCACCTGCGCGCCTTTTACGTCCCGCCCTTCATCATTGAGCAATG GGCCGCCGAGCCGTGCTCCATGCAGCAAGCTCCAACCCTCGACTTTGTCCTCTATGGCGGCGGGCCCCTCTCCCC CCAAACAGGCGACAGACTGAGCCGCGCCACCAGCGTCTGCCAAATGTACGGCTCGCTTGAACTCGGCCAGATCCA GCTGCTGGTGCCGGAGCGCGCCGAGTGGGCGCACATGGAGCTGAATCCGCATGAAGAGGCCGACATGCAGCCCCT GGGCGACGGCACGTATGAAATGGTGCTGCACCAGCATGAAAAGTTTGCCACGCGCCGCAGCCTGTGGCACAACTT CCCTGGCGTGCAGACGTGGCGCACAGGAGACTTGTTTCTGCCCCATCCGTCAAAACAGGGGCTGTGGCGCTTCCA CTCGCGAGTCGACGACTTGGTGGTGCTGTCGAGCAGCCATAAGCTCCGCCCGCTCGAGATGGAGACGATTATCCA GGGCCATGAGCTTGTTGCCGGAGCTATTATTGTCGGGCAGGGCAAGCCGGAGCCGCTGCTCATTGTCGAGCCGAG AGAGGGCGCCTTCAACGGCCACGAGCCGCGCTTCATTGATGCTATTTGGACAGCGGTGCAGGAAGCAAACGAAAT TGCACCCAGCTACGCGCAGATTAAGCGCAGCAATGTCCTCGTCTCCAAGCCTGAGCGGCCCTTTATCCGCGCCCC CAAAGGCAGCATTGTTCGCAAACTCACCATTGCGGCCTATGCCGACGACATTGAAGCTGCCTACGCCGCCGACGC TCCGCCAAGCAAGGCGACAATGCCGGCACAGGGCATGGATGGCTTCGTCTTGCCCGGGCTGAAGCAAATGGTGCG CGCCCACGTTGAAGACGAGCTTCCCGGCGTCACCATTTCAGACGCGGATAGCTTGTTTGCCCGCGGCCTCGACTC CATGGGCTGCGCGCGTCTGAGCCGGAGCTTGCAAAAGACGCTGGCGGCTCAGGGCAGCACCGACGGAAGCTGTGC CTTGACGATGCGCATGATTTACAAGTATCCCTCCATAGAGGGCCTGGCAACGGTGGTGCTAAACATTGTCTTTAA CCGCACGCTGCCCGACGTGTCGATTGGAAGCGACACCAAGATGATGAAGAGCGCGCTCGAGACGCTCACGCAGAA CCTGCCCGCCAGAAAAGCAACACGTGCTGCTCCTACCGAGGCCCTGACTATTGTCTTGATTGGGCCGCGTGGGTC GCTGGGGCCTCATATTGTGCGCCAGCTGCTGCAGAGTCGTCGAGTGGCCAAGATTTACAGTCTGAATAGGGGGCA GCATGGCCGAGAGAGGATGCGCGCCCTCGTCAAGCAGCGAGGCTTGGCTCTCGACGTGGACGATGCTCGTCTGTG TTTTATGCCGTTTGAGCTTGGCAAACCCCATCTCGGTCTCAGTGACGAGGATTACGCTCTCGTGCTGCGCAGCGC CAACCTCGTCATTCACAATGCGTGGAAAATCGACTTCAACTGGACCATTGAGCAGTACCAGGCCGACTATCTGCC CAGCGTGCGCCATCTCGTCGACTTTTCCGCCGAGAGCCCTCTCTCGCCTCGCATCGTCTTCATCTCTTCCATTTC TTCTGTTCAGGAATGGGCCGCTGTTTTCCCCACCCCCGTGACTGAAGAGCCTCTTGAATCCTTCCAGGTCGCCTC GCCTCTGGGCTACGGCCAGTCCAAGCACGTTTCTGAGCGCATCCTCACGGCAGCGAGTGCCATTTCCGGCACCCC AGTCACCATTCTCCGCGTCGGCCAGATTGCCGGCTCGACTACGGGAAGCGGCGGCGCCTGGACTCCTGATGAATG GGTTCCCTCGCTCGCCTCCATTTCTCGCTCCCTCAACAAAGTCCCCGTCGATATTCCGCCCATTGACTGGGTTCC CGCCAATCTCGCCGCCCAAGCCATTGCTGAGCTCGCTCTCAACGACTCTTGTCCTCCTCTCCGCGTTTTCAACAT TGTCAATCCAAAGCTCTCTCCTTGGTTTACCTTTGTTAAAGCCCTGCAGAGCCGTCTGGGAGACTCTGTGCAGGC GGTTACGCTGGCAGAATGGGTATCTGCCCTTGTGGGCACAGATCCAAAGTCCATGTCGGATGCGGCTGCCACGTC TTCGACCAAGCTGCTTCCCTTTTTCCAGCACTTGGCGCAGACGGCGGCAAAGGGCGTTGCGCTGCAGCCGAGGTT TGAGACGGGCAAGGCCATGGGGGCTAGTGAGACCATGGCTGGCATGGCGGCCATTGATGAGCGTGTTATTGACAT TTGGCTTCAGCAGTGGGATATTTGA

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