© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | OphauB2|1842 |
| Gene name | |
| Location | Contig_152:570..2064 |
| Strand | - |
| Gene length (bp) | 1494 |
| Transcript length (bp) | 1368 |
| Coding sequence length (bp) | 1368 |
| Protein length (aa) | 456 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF00067 | p450 | Cytochrome P450 | 2.0E-11 | 62 | 425 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P22680|CP7A1_HUMAN | Cholesterol 7-alpha-monooxygenase OS=Homo sapiens GN=CYP7A1 PE=1 SV=2 | 29 | 445 | 2.0E-13 |
| sp|P18125|CP7A1_RAT | Cholesterol 7-alpha-monooxygenase OS=Rattus norvegicus GN=Cyp7a1 PE=1 SV=1 | 29 | 429 | 5.0E-12 |
| sp|O46491|CP7A1_PIG | Cholesterol 7-alpha-monooxygenase OS=Sus scrofa GN=CYP7A1 PE=3 SV=1 | 29 | 445 | 7.0E-12 |
| sp|O75881|CP7B1_HUMAN | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Homo sapiens GN=CYP7B1 PE=1 SV=2 | 20 | 443 | 1.0E-11 |
| sp|Q64505|CP7A1_MOUSE | Cholesterol 7-alpha-monooxygenase OS=Mus musculus GN=Cyp7a1 PE=2 SV=2 | 29 | 443 | 2.0E-11 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P22680|CP7A1_HUMAN | Cholesterol 7-alpha-monooxygenase OS=Homo sapiens GN=CYP7A1 PE=1 SV=2 | 29 | 445 | 2.0E-13 |
| sp|P18125|CP7A1_RAT | Cholesterol 7-alpha-monooxygenase OS=Rattus norvegicus GN=Cyp7a1 PE=1 SV=1 | 29 | 429 | 5.0E-12 |
| sp|O46491|CP7A1_PIG | Cholesterol 7-alpha-monooxygenase OS=Sus scrofa GN=CYP7A1 PE=3 SV=1 | 29 | 445 | 7.0E-12 |
| sp|O75881|CP7B1_HUMAN | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Homo sapiens GN=CYP7B1 PE=1 SV=2 | 20 | 443 | 1.0E-11 |
| sp|Q64505|CP7A1_MOUSE | Cholesterol 7-alpha-monooxygenase OS=Mus musculus GN=Cyp7a1 PE=2 SV=2 | 29 | 443 | 2.0E-11 |
| sp|P46634|CP7A1_CRIGR | Cholesterol 7-alpha-monooxygenase OS=Cricetulus griseus GN=CYP7A1 PE=3 SV=1 | 29 | 445 | 5.0E-11 |
| sp|P51542|CP7A1_RABIT | Cholesterol 7-alpha-monooxygenase OS=Oryctolagus cuniculus GN=CYP7A1 PE=1 SV=1 | 29 | 445 | 7.0E-11 |
| sp|Q63688|CP7B1_RAT | 25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) OS=Rattus norvegicus GN=Cyp7b1 PE=1 SV=1 | 121 | 443 | 7.0E-11 |
| sp|Q60991|CP7B1_MOUSE | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Mus musculus GN=Cyp7b1 PE=2 SV=2 | 183 | 443 | 2.0E-10 |
| sp|Q6Z5I7|C76M6_ORYSJ | Oryzalexin E synthase OS=Oryza sativa subsp. japonica GN=CYP76M6 PE=1 SV=1 | 198 | 410 | 2.0E-09 |
| sp|O65790|C81F1_ARATH | Cytochrome P450 81F1 OS=Arabidopsis thaliana GN=CYP81F1 PE=2 SV=2 | 194 | 443 | 2.0E-08 |
| sp|Q7KR10|CCD1D_DROME | Probable cytochrome P450 12d1 distal, mitochondrial OS=Drosophila melanogaster GN=Cyp12d1-d PE=2 SV=1 | 203 | 416 | 3.0E-08 |
| sp|Q6YTF1|C76M8_ORYSJ | Oryzalexin D synthase OS=Oryza sativa subsp. japonica GN=CYP76M8 PE=1 SV=1 | 197 | 413 | 7.0E-08 |
| sp|P82712|CCD1P_DROME | Probable cytochrome P450 12d1 proximal, mitochondrial OS=Drosophila melanogaster GN=Cyp12d1-p PE=2 SV=3 | 203 | 416 | 8.0E-08 |
| sp|Q69X58|C76M7_ORYSJ | Ent-cassadiene C11-alpha-hydroxylase 1 OS=Oryza sativa subsp. japonica GN=CYP76M7 PE=1 SV=1 | 230 | 410 | 5.0E-07 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0004497 | monooxygenase activity | Yes |
| GO:0020037 | heme binding | Yes |
| GO:0005506 | iron ion binding | Yes |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Yes |
| GO:0003824 | catalytic activity | No |
| GO:0046872 | metal ion binding | No |
| GO:0046906 | tetrapyrrole binding | No |
| GO:0003674 | molecular_function | No |
| GO:0005488 | binding | No |
| GO:1901363 | heterocyclic compound binding | No |
| GO:0016491 | oxidoreductase activity | No |
| GO:0097159 | organic cyclic compound binding | No |
| GO:0043167 | ion binding | No |
| GO:0046914 | transition metal ion binding | No |
| GO:0043169 | cation binding | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 19 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >OphauB2|1842 MYIYVLKYFLGIPEPALSVYRADDSGPLSKAYPHSNVEPQNRVDHIIHHQYFRAYSGPGLDPTVKRFKHSLDRRI EGMHWDDNWTQEGNIESLFQHVAAASVIECIFGPALLRLNPNFVQDVWKFDDFVPWFPRAIPAFFMPESYRLRER LRGQLQRWYQYARLHFQESDINEDGDGDAFWGSELMRERQRTLRQVPHHDDYVLASMDMGFAWGTVGNTIPVSML ATIHVYKDPSLLERVRRSIAETLGQRSLMDLDPRELADIPLLSSIYTEVLRVYVNNYFVVSSPHQDVELGQWRLP KGQIGLLNSNISQMDKTFWNTKDGLYPVETFWADRFIIDPADASSGPILPALRKTSLRAEQSGDGKPYFSTEGIE GSWFPYGGGYSICPGRFLAKRAGVFTCAYLVHGYDVEVGQEEIHLDTCRFGLGIGALKKPIPFRIRKRRLESEAA CVKTE* |
| Coding | >OphauB2|1842 ATGTACATTTACGTATTGAAATATTTCTTGGGCATCCCGGAACCAGCCTTGTCAGTCTATCGAGCCGATGATTCA GGTCCGCTCTCCAAAGCGTACCCGCATAGCAATGTTGAGCCGCAGAACCGCGTCGATCATATTATCCATCATCAA TATTTCCGGGCGTATAGCGGCCCTGGACTGGATCCAACAGTGAAGCGTTTCAAACACTCGCTCGACAGGAGGATA GAGGGCATGCACTGGGACGACAATTGGACACAAGAGGGCAATATCGAGTCCCTTTTCCAACACGTTGCAGCTGCG TCAGTGATTGAGTGCATCTTTGGGCCCGCCTTGCTTCGTCTGAATCCCAATTTTGTGCAAGATGTATGGAAGTTT GACGACTTTGTTCCGTGGTTCCCTCGAGCTATTCCAGCCTTTTTCATGCCCGAGTCGTATAGGCTGCGGGAGCGA CTCAGAGGTCAGTTACAGCGGTGGTATCAATACGCGAGACTGCACTTTCAGGAATCCGACATTAATGAGGATGGT GACGGCGATGCCTTTTGGGGATCAGAGTTGATGAGAGAGCGACAAAGGACGTTGCGGCAGGTGCCACACCATGAC GACTATGTCCTTGCTTCCATGGACATGGGTTTCGCCTGGGGTACGGTGGGGAATACTATTCCTGTCTCGATGCTT GCGACGATACACGTATACAAGGATCCGAGTCTCCTTGAGCGTGTGCGGAGAAGCATTGCCGAGACTCTGGGCCAA CGCTCTCTCATGGACTTGGATCCTCGAGAACTGGCCGATATTCCGCTTCTATCATCCATATATACAGAGGTACTT CGTGTATACGTCAACAATTACTTTGTCGTTAGTTCGCCGCATCAAGATGTTGAGCTAGGGCAATGGCGGCTGCCC AAGGGCCAGATTGGCCTCCTCAATTCGAATATTTCCCAAATGGACAAGACCTTTTGGAACACCAAAGATGGCTTG TACCCAGTCGAAACCTTTTGGGCTGACCGCTTCATAATCGACCCGGCGGATGCATCGAGCGGACCCATCCTACCG GCGCTGAGGAAGACGTCACTGCGTGCCGAGCAGAGCGGCGACGGGAAGCCGTACTTTTCAACCGAGGGCATTGAG GGGTCCTGGTTTCCATATGGCGGTGGCTACTCCATTTGTCCTGGTAGGTTCCTGGCAAAGCGGGCTGGTGTCTTT ACCTGTGCCTATTTAGTGCACGGATACGATGTTGAAGTTGGGCAAGAGGAGATTCATCTCGACACTTGCAGGTTT GGACTGGGGATTGGAGCTTTGAAAAAGCCGATTCCCTTTCGGATTAGAAAGAGAAGGCTCGAGTCTGAAGCTGCA TGTGTCAAGACGGAATGA |
| Transcript | >OphauB2|1842 ATGTACATTTACGTATTGAAATATTTCTTGGGCATCCCGGAACCAGCCTTGTCAGTCTATCGAGCCGATGATTCA GGTCCGCTCTCCAAAGCGTACCCGCATAGCAATGTTGAGCCGCAGAACCGCGTCGATCATATTATCCATCATCAA TATTTCCGGGCGTATAGCGGCCCTGGACTGGATCCAACAGTGAAGCGTTTCAAACACTCGCTCGACAGGAGGATA GAGGGCATGCACTGGGACGACAATTGGACACAAGAGGGCAATATCGAGTCCCTTTTCCAACACGTTGCAGCTGCG TCAGTGATTGAGTGCATCTTTGGGCCCGCCTTGCTTCGTCTGAATCCCAATTTTGTGCAAGATGTATGGAAGTTT GACGACTTTGTTCCGTGGTTCCCTCGAGCTATTCCAGCCTTTTTCATGCCCGAGTCGTATAGGCTGCGGGAGCGA CTCAGAGGTCAGTTACAGCGGTGGTATCAATACGCGAGACTGCACTTTCAGGAATCCGACATTAATGAGGATGGT GACGGCGATGCCTTTTGGGGATCAGAGTTGATGAGAGAGCGACAAAGGACGTTGCGGCAGGTGCCACACCATGAC GACTATGTCCTTGCTTCCATGGACATGGGTTTCGCCTGGGGTACGGTGGGGAATACTATTCCTGTCTCGATGCTT GCGACGATACACGTATACAAGGATCCGAGTCTCCTTGAGCGTGTGCGGAGAAGCATTGCCGAGACTCTGGGCCAA CGCTCTCTCATGGACTTGGATCCTCGAGAACTGGCCGATATTCCGCTTCTATCATCCATATATACAGAGGTACTT CGTGTATACGTCAACAATTACTTTGTCGTTAGTTCGCCGCATCAAGATGTTGAGCTAGGGCAATGGCGGCTGCCC AAGGGCCAGATTGGCCTCCTCAATTCGAATATTTCCCAAATGGACAAGACCTTTTGGAACACCAAAGATGGCTTG TACCCAGTCGAAACCTTTTGGGCTGACCGCTTCATAATCGACCCGGCGGATGCATCGAGCGGACCCATCCTACCG GCGCTGAGGAAGACGTCACTGCGTGCCGAGCAGAGCGGCGACGGGAAGCCGTACTTTTCAACCGAGGGCATTGAG GGGTCCTGGTTTCCATATGGCGGTGGCTACTCCATTTGTCCTGGTAGGTTCCTGGCAAAGCGGGCTGGTGTCTTT ACCTGTGCCTATTTAGTGCACGGATACGATGTTGAAGTTGGGCAAGAGGAGATTCATCTCGACACTTGCAGGTTT GGACTGGGGATTGGAGCTTTGAAAAAGCCGATTCCCTTTCGGATTAGAAAGAGAAGGCTCGAGTCTGAAGCTGCA TGTGTCAAGACGGAATGA |
| Gene | >OphauB2|1842 ATGTACATTTACGTATTGAAATATTTCTTGGGCATCCCGGAACCAGCCTTGTCAGTCTATCGAGCCGATGATTCA GGTCCGCTCTCCAAAGCGTACCCGCATAGCAATGTTGAGCCGCAGAACCGCGTCGATCATATTATCCATCATCAA TATTTCCGGGCGTATAGCGGCCCTGGACTGGATCCAACAGTGAAGCGTTTCAAACACTCGCTCGACAGGAGGATA GAGGGCATGCACTGGGACGACAATTGGACACAAGAGGGCAATATCGAGTCCCTTTTCCAACACGTTGCAGCTGCG TCAGTGATTGAGTGCATCTTTGGGCCCGCCTTGCTTCGTCTGAATCCCAATTTTGTGCAAGATGTATGGAAGTTT GACGACTTTGTTCCGTGGTTCCCTCGAGCTATTCCAGCCTTTTTCATGCCCGAGTCGTATAGGCTGCGGGAGCGA CTCAGAGGTCAGTTACAGCGGTGGTATCAATACGCGAGACTGCACTTTCAGGAATCCGACATTAATGAGGATGGT GACGGCGATGCCTTTTGGGGATCAGAGTTGATGAGAGAGCGACAAAGGACGTTGCGGCAGGTGCCACACCATGAC GACTATGTCCTTGCTTCCATGGACATGGGTTTCGCCTGGGGGTAGGAATGGCGCCAAGCCATGTTTACTATACGA ACCAAGGCTAATGTTTCCATAGTACGGTGGGGAATACTATTCCTGTCTCGATGCTTGCGACGATACACGTATACA AGGATCCGAGTCTCCTTGAGCGTGTGCGGAGAAGCATTGCCGAGACTCTGGGCCAACGCTCTCTCATGGACTTGG ATCCTCGAGAACTGGCCGATATTCCGCTTCTATCATCCATATATACAGAGGTACTTCGTGTATACGTCAACAATT ACTTTGTCGTTAGTTCGCCGCATCAAGATGTTGAGCTAGGGCAATGGCGGCTGCCCAAGGGCCAGATTGGCCTCC TCAATTCGAATATTTCCCAAATGGACAAGACCTTTTGGAACACCAAAGATGGCTTGTACCCAGTCGAAACCTTTT GGGCTGACCGCTTCATAATCGACCCGGCGGATGCATCGAGCGGACCCATCCTACCGGCGCTGAGGAAGACGTCAC TGCGTGCCGAGCAGAGCGGCGACGGGAAGCCGTACTTTTCAACCGAGGGCATTGAGGGGTCCTGGTTTCCATATG GCGGTAGGTTTTACCCTTGGCGTGAAGAGTTGATTCGCCCAACGCAGTAATGTGTTGACTGATGAATGTAAAGGT GGCTACTCCATTTGTCCTGGTAGGTTCCTGGCAAAGCGGGCTGGTGTCTTTACCTGTGCCTATTTAGTGCACGGA TACGATGTTGAAGTTGGGCAAGAGGAGATTCATCTCGACACTTGCAGGTTTGGACTGGGGATTGGAGCTTTGAAA AAGCCGATTCCCTTTCGGATTAGAAAGAGAAGGCTCGAGTCTGAAGCTGCATGTGTCAAGACGGAATGA |