© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|8759 |
| Gene name | |
| Location | Contig_593:9885..13362 |
| Strand | + |
| Gene length (bp) | 3477 |
| Transcript length (bp) | 3270 |
| Coding sequence length (bp) | 3270 |
| Protein length (aa) | 1090 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF00172 | Zn_clus | Fungal Zn(2)-Cys(6) binuclear cluster domain | 1.1E-06 | 727 | 756 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P87234|GYP3_SCHPO | GTPase-activating protein gyp3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gyp3 PE=1 SV=1 | 537 | 663 | 8.0E-34 |
| sp|P48566|GYP3_YEAST | GTPase-activating protein GYP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSB3 PE=1 SV=1 | 540 | 665 | 2.0E-32 |
| sp|Q12317|MSB4_YEAST | GTPase-activating protein MSB4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSB4 PE=1 SV=1 | 477 | 662 | 9.0E-32 |
| sp|Q6PBU5|GRT1A_DANRE | Growth hormone-regulated TBC protein 1-A OS=Danio rerio GN=grtp1a PE=2 SV=1 | 522 | 665 | 2.0E-15 |
| sp|Q5TC63|GRTP1_HUMAN | Growth hormone-regulated TBC protein 1 OS=Homo sapiens GN=GRTP1 PE=1 SV=4 | 540 | 665 | 2.0E-14 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P87234|GYP3_SCHPO | GTPase-activating protein gyp3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=gyp3 PE=1 SV=1 | 537 | 663 | 8.0E-34 |
| sp|P48566|GYP3_YEAST | GTPase-activating protein GYP3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSB3 PE=1 SV=1 | 540 | 665 | 2.0E-32 |
| sp|Q12317|MSB4_YEAST | GTPase-activating protein MSB4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSB4 PE=1 SV=1 | 477 | 662 | 9.0E-32 |
| sp|Q6PBU5|GRT1A_DANRE | Growth hormone-regulated TBC protein 1-A OS=Danio rerio GN=grtp1a PE=2 SV=1 | 522 | 665 | 2.0E-15 |
| sp|Q5TC63|GRTP1_HUMAN | Growth hormone-regulated TBC protein 1 OS=Homo sapiens GN=GRTP1 PE=1 SV=4 | 540 | 665 | 2.0E-14 |
| sp|Q9D3N8|GRTP1_MOUSE | Growth hormone-regulated TBC protein 1 OS=Mus musculus GN=Grtp1 PE=1 SV=1 | 540 | 665 | 2.0E-12 |
| sp|Q6GLZ0|GRTP1_XENLA | Growth hormone-regulated TBC protein 1 OS=Xenopus laevis GN=grtp1 PE=2 SV=1 | 540 | 663 | 1.0E-11 |
| sp|O93870|FCR1_CANAX | Fluconazole resistance protein 1 OS=Candida albicans GN=FCR1 PE=3 SV=1 | 721 | 795 | 2.0E-11 |
| sp|Q6GL87|GRTP1_XENTR | Growth hormone-regulated TBC protein 1 OS=Xenopus tropicalis GN=grtp1 PE=2 SV=1 | 540 | 663 | 6.0E-11 |
| sp|Q5SVR0|TBC9B_MOUSE | TBC1 domain family member 9B OS=Mus musculus GN=Tbc1d9b PE=1 SV=1 | 596 | 663 | 3.0E-06 |
| sp|Q66K14|TBC9B_HUMAN | TBC1 domain family member 9B OS=Homo sapiens GN=TBC1D9B PE=1 SV=3 | 595 | 663 | 4.0E-06 |
| sp|Q9BXI6|TB10A_HUMAN | TBC1 domain family member 10A OS=Homo sapiens GN=TBC1D10A PE=1 SV=1 | 564 | 662 | 5.0E-06 |
| sp|P58802|TB10A_MOUSE | TBC1 domain family member 10A OS=Mus musculus GN=Tbc1d10a PE=1 SV=1 | 565 | 662 | 6.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | Yes |
| GO:0006355 | regulation of transcription, DNA-templated | Yes |
| GO:0008270 | zinc ion binding | Yes |
| GO:0009889 | regulation of biosynthetic process | No |
| GO:0050789 | regulation of biological process | No |
| GO:0008150 | biological_process | No |
| GO:0010468 | regulation of gene expression | No |
| GO:0005488 | binding | No |
| GO:2001141 | regulation of RNA biosynthetic process | No |
| GO:0050794 | regulation of cellular process | No |
| GO:0031323 | regulation of cellular metabolic process | No |
| GO:0019219 | regulation of nucleobase-containing compound metabolic process | No |
| GO:0051252 | regulation of RNA metabolic process | No |
| GO:0140110 | transcription regulator activity | No |
| GO:0010556 | regulation of macromolecule biosynthetic process | No |
| GO:1903506 | regulation of nucleic acid-templated transcription | No |
| GO:0019222 | regulation of metabolic process | No |
| GO:0003700 | DNA-binding transcription factor activity | No |
| GO:0031326 | regulation of cellular biosynthetic process | No |
| GO:0043169 | cation binding | No |
| GO:0065007 | biological regulation | No |
| GO:0043167 | ion binding | No |
| GO:0046872 | metal ion binding | No |
| GO:0051171 | regulation of nitrogen compound metabolic process | No |
| GO:0060255 | regulation of macromolecule metabolic process | No |
| GO:0003674 | molecular_function | No |
| GO:0046914 | transition metal ion binding | No |
| GO:0080090 | regulation of primary metabolic process | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 52 | 0.45 |
| Transcription Factor Class (based on PFAM domains) |
|---|
| Fungal Specific TF |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|8759 MAVSQFDDGAVERQRSVRNRQCSVYASRIRPAIAPLNLDAASAPGRVAPVPEVPPMPVSPRWDSLSNGSHLINHS PTSSPGHPLDDSWSELPYRPFVASPARPVFEQPSSAAADGAESPGKSPSKAASAWAASKPRTFRSDVRSSDGVAV ENFSRPRKQSIRQPVIPEQCAPEPAVPRLANLSPTDLLYEIGSTASPQTPPWPAPRRPSASSCKSASPFSSPLGP PPPVELPEPRPPFAAGQRVDGNSASSPMAGSGAPPPWMADDELRSSFRSQLTASSAYGTALTERSSVLTKDSSVT SLYANADEPSLEDVMCMYEKGFADDDDDDDDDDVEEDDEDTDFDEGPAADPHNRHHHHHHHHHHYHHAGNPSASP ARAADAARHLEPAAASDQGRPVTAMSAPEPGDQSADVDLMPPLPPPARSALDAEIRQSKMIFTSPAFTASVPALS AHVDLDVIAEKRDSGKSLDSEPSVSSDPASAANEGKKATATPLTSTPTSILSTSSTTTTKTTVSPPAIPPSPSSA AFRAAMEPEDPGSRDRYGFKKQNQFITREQYDSWNKGYTQYLARRHKKWATYLKECGLMTDRPIRFPPPNAKTKR FVRKGIPPDWRGAAWFYYAGGPAILAKHSGLYEKLLDREAKPIDVEAIERDLHRTFPDNIQFQPSPPAEDSKTTL SRKNTTSSTSSKSVKSTSRVSKRANSTAAATVHHDHVAHGVGMDGRHKRVWKACERCRMKKTKCDGEFPCKRCKD DGMVCTAGVRKKVEYKQLPKGYAEVLENTQFALIATVHKLYSMVRSAQPWELGEPELNDRGQPVIHNIAQRLGCI RPNSDIDLPVHSVFPEDEAGMAELARQLEEQQQQRQAQAQAHHHHQQLMQQQQQQQQQPHHHHHQHHHQQHHPPP PSDAAFSSHDTLDSASAKLSRTERGSSSELDQSDSELDYRPVPAGFRRAPPAFHAVSPPSFASTRASTGTTADFD FSPPHAPAAAAEQHLDTASLFASTHSPAVPSGAAFPGWAVPPKVGHPQPGDEMTLHFMDHDGLPALGLNQTLVES DFAALKADHLLPQPELNVMMGMGDPMICSAFVDGETMRL* |
| Coding | >Hirsu2|8759 ATGGCCGTCTCCCAGTTCGACGACGGCGCCGTCGAGCGCCAGCGGAGTGTCCGCAACCGCCAGTGTTCCGTCTAT GCATCCCGCATCAGGCCCGCCATCGCACCCCTGAACCTCGACGCCGCCTCGGCCCCGGGCCGCGTGGCCCCGGTG CCCGAGGTGCCGCCCATGCCCGTCTCGCCGCGCTGGGATTCGCTGTCGAACGGATCCCACCTCATCAACCACAGC CCGACGTCGTCGCCCGGCCACCCGCTCGACGACTCGTGGTCGGAGCTGCCGTACCGGCCCTTTGTCGCGTCGCCC GCCCGGCCCGTCTTCGAGCAGCCGTCGAGCGCCGCCGCCGACGGGGCCGAGTCGCCCGGCAAATCGCCGTCCAAG GCGGCCAGTGCCTGGGCGGCCAGCAAGCCGCGCACTTTTCGCTCCGACGTGCGCTCGTCGGACGGTGTGGCCGTG GAGAATTTCTCGCGCCCGCGCAAGCAGAGCATCCGCCAGCCTGTCATCCCGGAACAATGTGCTCCGGAGCCGGCC GTGCCGCGACTAGCCAACCTGTCGCCCACGGACCTCCTGTACGAGATTGGCTCGACCGCATCCCCCCAAACACCC CCCTGGCCGGCTCCCAGACGGCCATCTGCCTCATCCTGCAAATCCGCGTCCCCCTTCTCCTCGCCCCTCGGCCCT CCACCGCCCGTCGAACTGCCCGAACCAAGGCCCCCATTTGCCGCTGGCCAACGCGTCGACGGTAACAGCGCCTCG TCGCCCATGGCCGGCAGTGGGGCCCCGCCGCCCTGGATGGCCGACGACGAGTTGCGGTCCAGTTTCAGGTCCCAA CTCACCGCGTCGTCGGCCTACGGCACCGCCCTGACGGAGCGCAGCAGCGTCCTGACAAAGGACAGCTCCGTCACC TCGCTCTACGCCAACGCCGACGAGCCCAGCCTCGAGGATGTTATGTGCATGTACGAGAAGGGCTTCGCTGACGAC GACGACGACGACGACGACGACGACGTAGAAGAAGACGACGAAGACACCGACTTCGACGAAGGTCCCGCCGCCGAC CCGCACAACCGTCACCACCACCACCACCACCATCACCACCACTACCACCACGCCGGCAACCCGTCGGCCAGCCCA GCCCGCGCCGCCGACGCCGCCCGCCATCTCGAGCCCGCCGCCGCCTCGGATCAGGGCCGCCCCGTCACGGCCATG TCGGCGCCCGAACCGGGCGACCAGTCTGCCGACGTCGACCTGATGCCGCCGCTGCCCCCCCCGGCCCGGTCTGCG TTGGACGCCGAGATCCGCCAGTCCAAGATGATCTTCACCAGCCCCGCCTTCACCGCCTCCGTCCCGGCCCTGTCG GCTCACGTCGACCTGGACGTCATCGCCGAGAAGCGCGACTCGGGCAAGTCGCTCGACTCGGAGCCCTCCGTCTCG TCCGATCCCGCCTCGGCGGCCAATGAGGGCAAGAAGGCGACGGCGACGCCGCTGACGTCGACGCCGACATCGATA TTGTCGACGTCGTCGACGACGACGACGAAGACGACGGTCTCGCCCCCCGCCATCCCGCCCTCACCCTCGTCGGCG GCGTTCCGCGCGGCCATGGAGCCCGAGGACCCGGGCTCCCGCGACCGGTACGGCTTCAAGAAGCAGAACCAGTTC ATCACGAGGGAGCAGTATGACTCGTGGAACAAGGGGTACACGCAGTACCTGGCCCGCAGGCACAAGAAGTGGGCC ACGTACCTCAAGGAGTGCGGCCTGATGACGGACAGGCCTATACGTTTCCCGCCGCCCAACGCCAAGACGAAGCGG TTCGTGCGCAAGGGCATCCCCCCGGACTGGCGAGGCGCCGCCTGGTTCTACTACGCCGGCGGTCCCGCCATCCTG GCCAAGCACTCGGGCCTGTACGAGAAGCTGCTGGACCGCGAGGCCAAGCCGATCGACGTCGAGGCCATCGAGCGG GACCTGCACCGGACGTTCCCCGACAACATCCAGTTCCAGCCGTCGCCGCCGGCCGAGGACAGCAAGACGACGCTG TCGCGCAAGAACACGACGAGCTCGACGAGCTCCAAGTCGGTCAAGTCGACCAGCCGGGTCTCCAAGCGGGCCAAC TCGACGGCCGCCGCCACCGTACACCACGACCACGTCGCCCATGGCGTCGGCATGGACGGCCGCCACAAGCGGGTG TGGAAGGCGTGCGAGCGGTGTCGGATGAAGAAGACCAAGTGTGACGGCGAGTTTCCCTGCAAGCGATGCAAAGAC GACGGCATGGTCTGCACGGCCGGCGTGAGGAAAAAGGTCGAATACAAGCAATTACCAAAGGGATACGCCGAGGTG CTGGAGAACACGCAGTTCGCGCTCATCGCGACCGTCCACAAGCTGTACTCGATGGTGCGCAGCGCGCAGCCTTGG GAGCTGGGCGAGCCCGAGCTCAACGACCGCGGGCAGCCGGTGATCCACAACATCGCGCAGCGGCTGGGCTGCATC CGGCCCAACAGCGACATCGACCTGCCCGTCCACTCCGTCTTCCCCGAGGACGAGGCCGGCATGGCCGAGCTGGCG CGGCAGCTGGAGGAGCAGCAGCAGCAGCGGCAGGCGCAGGCGCAGGCGCACCACCACCACCAGCAGCTGATGCAG CAGCAGCAGCAGCAGCAGCAGCAGCCGCATCATCACCACCACCAGCACCACCACCAGCAGCACCACCCGCCGCCG CCGAGCGACGCCGCCTTCAGCAGCCACGACACGCTCGACTCGGCCTCGGCCAAGCTCAGCCGCACCGAGCGCGGC TCCTCGTCCGAGCTGGACCAGTCCGACAGCGAGCTCGACTACCGCCCGGTGCCGGCCGGCTTCCGGCGCGCCCCG CCGGCCTTCCACGCCGTGTCGCCGCCCAGCTTCGCCAGCACGCGCGCCAGCACCGGCACCACGGCCGACTTCGAC TTCAGCCCGCCGCACGCGCCCGCCGCCGCCGCCGAGCAGCACCTCGACACGGCCTCGCTCTTCGCCTCGACGCAC TCGCCCGCCGTGCCCTCCGGCGCCGCCTTCCCCGGCTGGGCCGTGCCGCCCAAGGTCGGCCACCCGCAGCCGGGC GACGAGATGACGCTGCACTTTATGGACCACGACGGCCTGCCCGCCCTCGGCCTCAACCAGACGCTCGTCGAGTCC GACTTCGCCGCCCTCAAGGCCGACCACCTGCTGCCCCAGCCGGAGCTCAACGTCATGATGGGCATGGGCGACCCC ATGATCTGCTCCGCCTTTGTCGACGGCGAGACCATGCGCCTCTAA |
| Transcript | >Hirsu2|8759 ATGGCCGTCTCCCAGTTCGACGACGGCGCCGTCGAGCGCCAGCGGAGTGTCCGCAACCGCCAGTGTTCCGTCTAT GCATCCCGCATCAGGCCCGCCATCGCACCCCTGAACCTCGACGCCGCCTCGGCCCCGGGCCGCGTGGCCCCGGTG CCCGAGGTGCCGCCCATGCCCGTCTCGCCGCGCTGGGATTCGCTGTCGAACGGATCCCACCTCATCAACCACAGC CCGACGTCGTCGCCCGGCCACCCGCTCGACGACTCGTGGTCGGAGCTGCCGTACCGGCCCTTTGTCGCGTCGCCC GCCCGGCCCGTCTTCGAGCAGCCGTCGAGCGCCGCCGCCGACGGGGCCGAGTCGCCCGGCAAATCGCCGTCCAAG GCGGCCAGTGCCTGGGCGGCCAGCAAGCCGCGCACTTTTCGCTCCGACGTGCGCTCGTCGGACGGTGTGGCCGTG GAGAATTTCTCGCGCCCGCGCAAGCAGAGCATCCGCCAGCCTGTCATCCCGGAACAATGTGCTCCGGAGCCGGCC GTGCCGCGACTAGCCAACCTGTCGCCCACGGACCTCCTGTACGAGATTGGCTCGACCGCATCCCCCCAAACACCC CCCTGGCCGGCTCCCAGACGGCCATCTGCCTCATCCTGCAAATCCGCGTCCCCCTTCTCCTCGCCCCTCGGCCCT CCACCGCCCGTCGAACTGCCCGAACCAAGGCCCCCATTTGCCGCTGGCCAACGCGTCGACGGTAACAGCGCCTCG TCGCCCATGGCCGGCAGTGGGGCCCCGCCGCCCTGGATGGCCGACGACGAGTTGCGGTCCAGTTTCAGGTCCCAA CTCACCGCGTCGTCGGCCTACGGCACCGCCCTGACGGAGCGCAGCAGCGTCCTGACAAAGGACAGCTCCGTCACC TCGCTCTACGCCAACGCCGACGAGCCCAGCCTCGAGGATGTTATGTGCATGTACGAGAAGGGCTTCGCTGACGAC GACGACGACGACGACGACGACGACGTAGAAGAAGACGACGAAGACACCGACTTCGACGAAGGTCCCGCCGCCGAC CCGCACAACCGTCACCACCACCACCACCACCATCACCACCACTACCACCACGCCGGCAACCCGTCGGCCAGCCCA GCCCGCGCCGCCGACGCCGCCCGCCATCTCGAGCCCGCCGCCGCCTCGGATCAGGGCCGCCCCGTCACGGCCATG TCGGCGCCCGAACCGGGCGACCAGTCTGCCGACGTCGACCTGATGCCGCCGCTGCCCCCCCCGGCCCGGTCTGCG TTGGACGCCGAGATCCGCCAGTCCAAGATGATCTTCACCAGCCCCGCCTTCACCGCCTCCGTCCCGGCCCTGTCG GCTCACGTCGACCTGGACGTCATCGCCGAGAAGCGCGACTCGGGCAAGTCGCTCGACTCGGAGCCCTCCGTCTCG TCCGATCCCGCCTCGGCGGCCAATGAGGGCAAGAAGGCGACGGCGACGCCGCTGACGTCGACGCCGACATCGATA TTGTCGACGTCGTCGACGACGACGACGAAGACGACGGTCTCGCCCCCCGCCATCCCGCCCTCACCCTCGTCGGCG GCGTTCCGCGCGGCCATGGAGCCCGAGGACCCGGGCTCCCGCGACCGGTACGGCTTCAAGAAGCAGAACCAGTTC ATCACGAGGGAGCAGTATGACTCGTGGAACAAGGGGTACACGCAGTACCTGGCCCGCAGGCACAAGAAGTGGGCC ACGTACCTCAAGGAGTGCGGCCTGATGACGGACAGGCCTATACGTTTCCCGCCGCCCAACGCCAAGACGAAGCGG TTCGTGCGCAAGGGCATCCCCCCGGACTGGCGAGGCGCCGCCTGGTTCTACTACGCCGGCGGTCCCGCCATCCTG GCCAAGCACTCGGGCCTGTACGAGAAGCTGCTGGACCGCGAGGCCAAGCCGATCGACGTCGAGGCCATCGAGCGG GACCTGCACCGGACGTTCCCCGACAACATCCAGTTCCAGCCGTCGCCGCCGGCCGAGGACAGCAAGACGACGCTG TCGCGCAAGAACACGACGAGCTCGACGAGCTCCAAGTCGGTCAAGTCGACCAGCCGGGTCTCCAAGCGGGCCAAC TCGACGGCCGCCGCCACCGTACACCACGACCACGTCGCCCATGGCGTCGGCATGGACGGCCGCCACAAGCGGGTG TGGAAGGCGTGCGAGCGGTGTCGGATGAAGAAGACCAAGTGTGACGGCGAGTTTCCCTGCAAGCGATGCAAAGAC GACGGCATGGTCTGCACGGCCGGCGTGAGGAAAAAGGTCGAATACAAGCAATTACCAAAGGGATACGCCGAGGTG CTGGAGAACACGCAGTTCGCGCTCATCGCGACCGTCCACAAGCTGTACTCGATGGTGCGCAGCGCGCAGCCTTGG GAGCTGGGCGAGCCCGAGCTCAACGACCGCGGGCAGCCGGTGATCCACAACATCGCGCAGCGGCTGGGCTGCATC CGGCCCAACAGCGACATCGACCTGCCCGTCCACTCCGTCTTCCCCGAGGACGAGGCCGGCATGGCCGAGCTGGCG CGGCAGCTGGAGGAGCAGCAGCAGCAGCGGCAGGCGCAGGCGCAGGCGCACCACCACCACCAGCAGCTGATGCAG CAGCAGCAGCAGCAGCAGCAGCAGCCGCATCATCACCACCACCAGCACCACCACCAGCAGCACCACCCGCCGCCG CCGAGCGACGCCGCCTTCAGCAGCCACGACACGCTCGACTCGGCCTCGGCCAAGCTCAGCCGCACCGAGCGCGGC TCCTCGTCCGAGCTGGACCAGTCCGACAGCGAGCTCGACTACCGCCCGGTGCCGGCCGGCTTCCGGCGCGCCCCG CCGGCCTTCCACGCCGTGTCGCCGCCCAGCTTCGCCAGCACGCGCGCCAGCACCGGCACCACGGCCGACTTCGAC TTCAGCCCGCCGCACGCGCCCGCCGCCGCCGCCGAGCAGCACCTCGACACGGCCTCGCTCTTCGCCTCGACGCAC TCGCCCGCCGTGCCCTCCGGCGCCGCCTTCCCCGGCTGGGCCGTGCCGCCCAAGGTCGGCCACCCGCAGCCGGGC GACGAGATGACGCTGCACTTTATGGACCACGACGGCCTGCCCGCCCTCGGCCTCAACCAGACGCTCGTCGAGTCC GACTTCGCCGCCCTCAAGGCCGACCACCTGCTGCCCCAGCCGGAGCTCAACGTCATGATGGGCATGGGCGACCCC ATGATCTGCTCCGCCTTTGTCGACGGCGAGACCATGCGCCTCTAA |
| Gene | >Hirsu2|8759 ATGGCCGTCTCCCAGTTCGACGACGGCGCCGTCGAGCGCCAGCGGAGTGTCCGCAACCGCCAGTGTTCCGTCTAT GCATCCCGCATCAGGCCCGCCATCGCACCCCTGAACCTCGACGCCGCCTCGGCCCCGGGCCGCGTGGCCCCGGTG CCCGAGGTGCCGCCCATGCCCGTCTCGCCGCGCTGGGATTCGCTGTCGAACGGATCCCACCTCATCAACCACAGC CCGACGTCGTCGCCCGGCCACCCGCTCGACGACTCGTGGTCGGAGCTGCCGTACCGGCCCTTTGTCGCGTCGCCC GCCCGGCCCGTCTTCGAGCAGCCGTCGAGCGCCGCCGCCGACGGGGCCGAGTCGCCCGGCAAATCGCCGTCCAAG GCGGCCAGTGCCTGGGCGGCCAGCAAGCCGCGCACTTTTCGCTCCGACGTGCGCTCGTCGGACGGTGTGGCCGTG GAGAATTTCTCGCGCCCGCGCAAGCAGAGCATCCGCCAGCCTGTCATCCCGGAACAATGTGCTCCGGAGCCGGCC GTGCCGCGACTAGCCAACCTGTCGCCCACGGACCTCCTGTACGAGATTGGCTCGACCGCATCCCCCCAAACACCC CCCTGGCCGGCTCCCAGACGGCCATCTGCCTCATCCTGCAAATCCGCGTCCCCCTTCTCCTCGCCCCTCGGCCCT CCACCGCCCGTCGAACTGCCCGAACCAAGGTTTGCCCGTATCCGGAATGCCGCCGGCCCGCCCCTAACGGCCGCC AGGCCCCCATTTGCCGCTGGCCAACGCGTCGACGGTAACAGCGCCTCGTCGCCCATGGCCGGCAGTGGGGCCCCG CCGCCCTGGATGGCCGACGACGAGTTGCGGTCCAGTTTCAGGTCCCAACTCACCGCGTCGTCGGCCTACGGCACC GCCCTGACGGAGCGCAGCAGCGTCCTGACAAAGGACAGCTCCGTCACCTCGCTCTACGCCAACGCCGACGAGCCC AGCCTCGAGGATGTTATGTGCATGTACGAGAAGGGCTTCGCTGACGACGACGACGACGACGACGACGACGACGTA GAAGAAGACGACGAAGACACCGACTTCGACGAAGGTCCCGCCGCCGACCCGCACAACCGTCACCACCACCACCAC CACCATCACCACCACTACCACCACGCCGGCAACCCGTCGGCCAGCCCAGCCCGCGCCGCCGACGCCGCCCGCCAT CTCGAGCCCGCCGCCGCCTCGGATCAGGGCCGCCCCGTCACGGCCATGTCGGCGCCCGAACCGGGCGACCAGTCT GCCGACGTCGACCTGATGCCGCCGCTGCCCCCCCCGGCCCGGTCTGCGTTGGACGCCGAGATCCGCCAGTCCAAG ATGATCTTCACCAGCCCCGCCTTCACCGCCTCCGTCCCGGCCCTGTCGGCTCACGTCGACCTGGACGTCATCGCC GAGAAGCGCGACTCGGGCAAGTCGCTCGACTCGGAGCCCTCCGTCTCGTCCGATCCCGCCTCGGCGGCCAATGAG GGCAAGAAGGCGACGGCGACGCCGCTGACGTCGACGCCGACATCGATATTGTCGACGTCGTCGACGACGACGACG AAGACGACGGTCTCGCCCCCCGCCATCCCGCCCTCACCCTCGTCGGCGGCGTTCCGCGCGGCCATGGAGCCCGAG GACCCGGGCTCCCGCGACCGGTACGGCTTCAAGAAGCAGAACCAGTTCATCACGAGGGAGCAGTATGACTCGTGG AACAAGGGGTACACGCAGTACCTGGCCCGCAGGCACAAGAAGTGGGCCACGTACCTCAAGGAGTGCGGCCTGATG ACGGACAGGCCTATACGTTTCCCGCCGCCCAACGCCAAGACGAAGCGGTTCGTGCGCAAGGGCATCCCCCCGGAC TGGCGAGGCGCCGCCTGGTTCTACTACGCCGGCGGTCCCGCCATCCTGGCCAAGCACTCGGGCCTGTACGAGAAG CTGCTGGACCGCGAGGCCAAGCCGATCGACGTCGAGGCCATCGAGCGGGACCTGCACCGGACGTTCCCCGACAAC ATCCAGTTCCAGCCGTCGCCGCCGGCCGAGGACAGCAAGACGACGCTGTCGCGCAAGAACACGACGAGCTCGACG AGCTCCAAGTCGGTCAAGTCGACCAGCCGGGTCTCCAAGCGGGCCAACTCGACGGCCGCCGCCACCGTACACCAC GACCACGTCGCCCATGGCGTCGGCATGGACGGCCGCCACAAGCGGGTGTGGAAGGCGTGCGAGCGGTGTCGGATG AAGAAGACCAAGGTTCGTCCACTTGCTCGCGAGAGAGAGAGAGAGAGAAGCAGGACAGGGAGGGGCTGACTCTGG GCCGCAGTGTGACGGCGAGTTTCCCTGCAAGCGATGCAAAGACGACGGCATGGTCTGCACGGCCGGCGTGAGGAA AAAGGTCGAATACAAGCAATTACCAAAGGGGTATGTCTCGTCGCTTTCCCGTCTCTTCGTGCCCGCATACCAGAC TCGCTCGTTCCCAACGCTGACCGGCGCCGCCTCCGCTTCTGCAGATACGCCGAGGTGCTGGAGAACACGCAGTTC GCGCTCATCGCGACCGTCCACAAGCTGTACTCGATGGTGCGCAGCGCGCAGCCTTGGGAGCTGGGCGAGCCCGAG CTCAACGACCGCGGGCAGCCGGTGATCCACAACATCGCGCAGCGGCTGGGCTGCATCCGGCCCAACAGCGACATC GACCTGCCCGTCCACTCCGTCTTCCCCGAGGACGAGGCCGGCATGGCCGAGCTGGCGCGGCAGCTGGAGGAGCAG CAGCAGCAGCGGCAGGCGCAGGCGCAGGCGCACCACCACCACCAGCAGCTGATGCAGCAGCAGCAGCAGCAGCAG CAGCAGCCGCATCATCACCACCACCAGCACCACCACCAGCAGCACCACCCGCCGCCGCCGAGCGACGCCGCCTTC AGCAGCCACGACACGCTCGACTCGGCCTCGGCCAAGCTCAGCCGCACCGAGCGCGGCTCCTCGTCCGAGCTGGAC CAGTCCGACAGCGAGCTCGACTACCGCCCGGTGCCGGCCGGCTTCCGGCGCGCCCCGCCGGCCTTCCACGCCGTG TCGCCGCCCAGCTTCGCCAGCACGCGCGCCAGCACCGGCACCACGGCCGACTTCGACTTCAGCCCGCCGCACGCG CCCGCCGCCGCCGCCGAGCAGCACCTCGACACGGCCTCGCTCTTCGCCTCGACGCACTCGCCCGCCGTGCCCTCC GGCGCCGCCTTCCCCGGCTGGGCCGTGCCGCCCAAGGTCGGCCACCCGCAGCCGGGCGACGAGATGACGCTGCAC TTTATGGACCACGACGGCCTGCCCGCCCTCGGCCTCAACCAGACGCTCGTCGAGTCCGACTTCGCCGCCCTCAAG GCCGACCACCTGCTGCCCCAGCCGGAGCTCAACGTCATGATGGGCATGGGCGACCCCATGATCTGCTCCGCCTTT GTCGACGGCGAGACCATGCGCCTCTAA |