© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|8514 |
| Gene name | |
| Location | Contig_560:6770..7655 |
| Strand | - |
| Gene length (bp) | 885 |
| Transcript length (bp) | 885 |
| Coding sequence length (bp) | 885 |
| Protein length (aa) | 295 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF04140 | ICMT | Isoprenylcysteine carboxyl methyltransferase (ICMT) family | 8.4E-27 | 180 | 272 |
| PF04191 | PEMT | Phospholipid methyltransferase | 1.2E-10 | 176 | 277 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P32584|STE14_YEAST | Protein-S-isoprenylcysteine O-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE14 PE=1 SV=1 | 106 | 293 | 8.0E-51 |
| sp|O12947|ICMT_XENLA | Protein-S-isoprenylcysteine O-methyltransferase OS=Xenopus laevis GN=icmt PE=2 SV=1 | 68 | 294 | 2.0E-47 |
| sp|Q9EQK7|ICMT_MOUSE | Protein-S-isoprenylcysteine O-methyltransferase OS=Mus musculus GN=Icmt PE=2 SV=2 | 71 | 294 | 5.0E-47 |
| sp|Q9WVM4|ICMT_RAT | Protein-S-isoprenylcysteine O-methyltransferase (Fragment) OS=Rattus norvegicus GN=Icmt PE=1 SV=1 | 71 | 294 | 1.0E-46 |
| sp|O60725|ICMT_HUMAN | Protein-S-isoprenylcysteine O-methyltransferase OS=Homo sapiens GN=ICMT PE=1 SV=1 | 71 | 294 | 2.0E-45 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P32584|STE14_YEAST | Protein-S-isoprenylcysteine O-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE14 PE=1 SV=1 | 106 | 293 | 8.0E-51 |
| sp|O12947|ICMT_XENLA | Protein-S-isoprenylcysteine O-methyltransferase OS=Xenopus laevis GN=icmt PE=2 SV=1 | 68 | 294 | 2.0E-47 |
| sp|Q9EQK7|ICMT_MOUSE | Protein-S-isoprenylcysteine O-methyltransferase OS=Mus musculus GN=Icmt PE=2 SV=2 | 71 | 294 | 5.0E-47 |
| sp|Q9WVM4|ICMT_RAT | Protein-S-isoprenylcysteine O-methyltransferase (Fragment) OS=Rattus norvegicus GN=Icmt PE=1 SV=1 | 71 | 294 | 1.0E-46 |
| sp|O60725|ICMT_HUMAN | Protein-S-isoprenylcysteine O-methyltransferase OS=Homo sapiens GN=ICMT PE=1 SV=1 | 71 | 294 | 2.0E-45 |
| sp|P87014|MAM4_SCHPO | Protein-S-isoprenylcysteine O-methyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mam4 PE=3 SV=1 | 106 | 293 | 3.0E-39 |
| sp|Q558K8|ICMT_DICDI | Protein-S-isoprenylcysteine O-methyltransferase OS=Dictyostelium discoideum GN=icmt-1 PE=2 SV=2 | 106 | 294 | 2.0E-32 |
| sp|Q93W54|ICMTB_ARATH | Protein-S-isoprenylcysteine O-methyltransferase B OS=Arabidopsis thaliana GN=ICMTB PE=1 SV=1 | 129 | 294 | 4.0E-28 |
| sp|Q7XSR9|ICMT_ORYSJ | Probable protein-S-isoprenylcysteine O-methyltransferase OS=Oryza sativa subsp. japonica GN=ICMT PE=3 SV=2 | 106 | 294 | 5.0E-25 |
| sp|A2XX73|ICMT_ORYSI | Probable protein-S-isoprenylcysteine O-methyltransferase OS=Oryza sativa subsp. indica GN=ICMT PE=3 SV=2 | 106 | 294 | 5.0E-25 |
| sp|Q9FMW9|ICMTA_ARATH | Protein-S-isoprenylcysteine O-methyltransferase A OS=Arabidopsis thaliana GN=ICMTA PE=1 SV=1 | 94 | 294 | 2.0E-24 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0004671 | protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity | Yes |
| GO:0006481 | C-terminal protein methylation | Yes |
| GO:0016021 | integral component of membrane | Yes |
| GO:0008171 | O-methyltransferase activity | No |
| GO:0008152 | metabolic process | No |
| GO:0008213 | protein alkylation | No |
| GO:0044260 | cellular macromolecule metabolic process | No |
| GO:0032259 | methylation | No |
| GO:0009987 | cellular process | No |
| GO:0018410 | C-terminal protein amino acid modification | No |
| GO:0031224 | intrinsic component of membrane | No |
| GO:0008276 | protein methyltransferase activity | No |
| GO:0006807 | nitrogen compound metabolic process | No |
| GO:0071704 | organic substance metabolic process | No |
| GO:0006479 | protein methylation | No |
| GO:0003824 | catalytic activity | No |
| GO:0019538 | protein metabolic process | No |
| GO:0010340 | carboxyl-O-methyltransferase activity | No |
| GO:0008150 | biological_process | No |
| GO:0016741 | transferase activity, transferring one-carbon groups | No |
| GO:0043687 | post-translational protein modification | No |
| GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity | No |
| GO:0016740 | transferase activity | No |
| GO:0043170 | macromolecule metabolic process | No |
| GO:0036211 | protein modification process | No |
| GO:0044237 | cellular metabolic process | No |
| GO:0043414 | macromolecule methylation | No |
| GO:0005575 | cellular_component | No |
| GO:0003674 | molecular_function | No |
| GO:0043412 | macromolecule modification | No |
| GO:0110165 | cellular anatomical entity | No |
| GO:0140096 | catalytic activity, acting on a protein | No |
| GO:1901564 | organonitrogen compound metabolic process | No |
| GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity | No |
| GO:0051998 | protein carboxyl O-methyltransferase activity | No |
| GO:0044238 | primary metabolic process | No |
| GO:0008168 | methyltransferase activity | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 26 | 0.45 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 71 | 93 | 22 |
| 2 | 100 | 122 | 22 |
| 3 | 137 | 159 | 22 |
| 4 | 172 | 194 | 22 |
| 5 | 238 | 260 | 22 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|8514 MSGGGADAQATGPQPRPPALEPRFRPYRPWESSSGRSSSGESSSGESSPAAGDESPLKPFFAGQPKSLSGIALRA FCLGLACAASALCLTAILLLSSSPVWRVPFFLLALSTFHFLEFWTTAERNTLVASVDSFLLTANWPAYGLAHMAA FLECAVVSVFFPDRVWAPHGSGPLLVALGLGLVLVGQAVRSAAMLEAGASFNHKVQTKKAGSHTLVTTGIYGAIR HPSYFGFFYWSLGTQLVMGNVMCFCVYAAVLWAFFNGRIRVEEAKLVEFFQKDYLDYRKRVGTRMPFIQ* |
| Coding | >Hirsu2|8514 ATGTCGGGCGGCGGCGCCGACGCCCAGGCCACCGGCCCTCAGCCGCGGCCGCCGGCCCTGGAGCCGCGATTTCGG CCGTACCGCCCGTGGGAGTCGTCGTCGGGGAGGTCGTCGTCGGGGGAGTCGTCGTCGGGGGAGTCGTCGCCCGCG GCCGGCGACGAGTCTCCGCTGAAGCCCTTCTTCGCCGGGCAGCCCAAGTCGCTGTCGGGCATCGCCCTGCGCGCC TTCTGCCTCGGGCTGGCCTGCGCCGCCAGCGCCCTTTGCCTGACGGCCATCCTGCTTCTCAGCAGCAGCCCGGTC TGGCGCGTGCCCTTCTTCCTCCTCGCCCTGTCGACCTTCCACTTCCTCGAGTTCTGGACGACGGCCGAGCGCAAC ACGCTCGTGGCCAGCGTCGACAGCTTCCTCCTGACGGCCAACTGGCCCGCTTACGGCCTCGCCCACATGGCCGCC TTCCTCGAGTGCGCCGTCGTCAGCGTCTTCTTCCCCGACCGCGTCTGGGCCCCCCACGGCTCCGGCCCCCTGCTC GTCGCCCTCGGCCTCGGCCTCGTGCTCGTCGGCCAGGCCGTCCGCTCGGCCGCCATGCTCGAGGCCGGCGCCAGC TTCAACCACAAGGTCCAGACGAAGAAGGCCGGCTCCCACACGCTCGTCACCACCGGTATCTACGGCGCCATCCGC CACCCGAGCTACTTTGGCTTCTTCTACTGGAGCCTCGGCACGCAGCTGGTCATGGGGAATGTTATGTGCTTCTGC GTCTATGCGGCCGTGCTTTGGGCCTTCTTCAACGGAAGGATAAGGGTGGAAGAGGCCAAGCTTGTCGAGTTCTTC CAGAAGGACTATCTCGATTACCGGAAGAGGGTAGGGACACGGATGCCTTTCATCCAGTGA |
| Transcript | >Hirsu2|8514 ATGTCGGGCGGCGGCGCCGACGCCCAGGCCACCGGCCCTCAGCCGCGGCCGCCGGCCCTGGAGCCGCGATTTCGG CCGTACCGCCCGTGGGAGTCGTCGTCGGGGAGGTCGTCGTCGGGGGAGTCGTCGTCGGGGGAGTCGTCGCCCGCG GCCGGCGACGAGTCTCCGCTGAAGCCCTTCTTCGCCGGGCAGCCCAAGTCGCTGTCGGGCATCGCCCTGCGCGCC TTCTGCCTCGGGCTGGCCTGCGCCGCCAGCGCCCTTTGCCTGACGGCCATCCTGCTTCTCAGCAGCAGCCCGGTC TGGCGCGTGCCCTTCTTCCTCCTCGCCCTGTCGACCTTCCACTTCCTCGAGTTCTGGACGACGGCCGAGCGCAAC ACGCTCGTGGCCAGCGTCGACAGCTTCCTCCTGACGGCCAACTGGCCCGCTTACGGCCTCGCCCACATGGCCGCC TTCCTCGAGTGCGCCGTCGTCAGCGTCTTCTTCCCCGACCGCGTCTGGGCCCCCCACGGCTCCGGCCCCCTGCTC GTCGCCCTCGGCCTCGGCCTCGTGCTCGTCGGCCAGGCCGTCCGCTCGGCCGCCATGCTCGAGGCCGGCGCCAGC TTCAACCACAAGGTCCAGACGAAGAAGGCCGGCTCCCACACGCTCGTCACCACCGGTATCTACGGCGCCATCCGC CACCCGAGCTACTTTGGCTTCTTCTACTGGAGCCTCGGCACGCAGCTGGTCATGGGGAATGTTATGTGCTTCTGC GTCTATGCGGCCGTGCTTTGGGCCTTCTTCAACGGAAGGATAAGGGTGGAAGAGGCCAAGCTTGTCGAGTTCTTC CAGAAGGACTATCTCGATTACCGGAAGAGGGTAGGGACACGGATGCCTTTCATCCAGTGA |
| Gene | >Hirsu2|8514 ATGTCGGGCGGCGGCGCCGACGCCCAGGCCACCGGCCCTCAGCCGCGGCCGCCGGCCCTGGAGCCGCGATTTCGG CCGTACCGCCCGTGGGAGTCGTCGTCGGGGAGGTCGTCGTCGGGGGAGTCGTCGTCGGGGGAGTCGTCGCCCGCG GCCGGCGACGAGTCTCCGCTGAAGCCCTTCTTCGCCGGGCAGCCCAAGTCGCTGTCGGGCATCGCCCTGCGCGCC TTCTGCCTCGGGCTGGCCTGCGCCGCCAGCGCCCTTTGCCTGACGGCCATCCTGCTTCTCAGCAGCAGCCCGGTC TGGCGCGTGCCCTTCTTCCTCCTCGCCCTGTCGACCTTCCACTTCCTCGAGTTCTGGACGACGGCCGAGCGCAAC ACGCTCGTGGCCAGCGTCGACAGCTTCCTCCTGACGGCCAACTGGCCCGCTTACGGCCTCGCCCACATGGCCGCC TTCCTCGAGTGCGCCGTCGTCAGCGTCTTCTTCCCCGACCGCGTCTGGGCCCCCCACGGCTCCGGCCCCCTGCTC GTCGCCCTCGGCCTCGGCCTCGTGCTCGTCGGCCAGGCCGTCCGCTCGGCCGCCATGCTCGAGGCCGGCGCCAGC TTCAACCACAAGGTCCAGACGAAGAAGGCCGGCTCCCACACGCTCGTCACCACCGGTATCTACGGCGCCATCCGC CACCCGAGCTACTTTGGCTTCTTCTACTGGAGCCTCGGCACGCAGCTGGTCATGGGGAATGTTATGTGCTTCTGC GTCTATGCGGCCGTGCTTTGGGCCTTCTTCAACGGAAGGATAAGGGTGGAAGAGGCCAAGCTTGTCGAGTTCTTC CAGAAGGACTATCTCGATTACCGGAAGAGGGTAGGGACACGGATGCCTTTCATCCAGTGA |