Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	Hirsu2|8399
Gene name
Location	Contig_546:5993..9515
Strand	-
Gene length (bp)	3522
Transcript length (bp)	3522
Coding sequence length (bp)	3522
Protein length (aa)	1174

Your browser does not support drawing a protein figure.

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF01375	Enterotoxin_a	Heat-labile enterotoxin alpha chain	6.2E-15	31	199

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|P01555|CHTA_VIBCH	Cholera enterotoxin subunit A OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) GN=ctxA PE=1 SV=1	21	199	2.0E-09
sp|P43530|ELAH_ECOH1	Heat-labile enterotoxin A chain OS=Escherichia coli O78:H11 (strain H10407 / ETEC) GN=eltA PE=3 SV=1	36	199	2.0E-08
sp|P06717|ELAP_ECOLX	Heat-labile enterotoxin A chain OS=Escherichia coli GN=eltA PE=1 SV=1	36	199	2.0E-08
sp|P43528|E2BA_ECOLX	Heat-labile enterotoxin IIB, A chain OS=Escherichia coli PE=1 SV=2	37	156	2.0E-07

GO

GO Term	Description	Terminal node
GO:0090729	toxin activity	Yes
GO:0005615	extracellular space	Yes
GO:0005575	cellular_component	No
GO:0003674	molecular_function	No
GO:0110165	cellular anatomical entity	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
Yes	1 - 25	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	5	27	22

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Hirsu2|8399 MYACWVHFVPLLVILLLWPASSFAYPTDSQNQPIILYRGDTRAPEEIKFQGGFLPPINPAPHDKYRITDHIRLVA APYGKAATPYISTTPDFIFASKFAKARARYGAKESFVYHVHATPHIFRAVDSVDQDPVTKGGAEGEYDALGGIPW RQILGWTPIPLDTTGESLMEYLAAADQYFVRNREYDTNFDQYSASGGQPLLNERNKDPAQGKTAYDYAIDFMNRP EIGACVGWKGEFPLFKTPDHDQKLAAARRANEEATEAAQGALAAVDRAEAALKDIEKAQSPMDAQKYAEMACIAR DRAVKLAREVAAKSEEYIIIKSDLYEAAMGAMRRAISVAAVASKIGNIKTAKDHAKEAERLAKLKDQESAIQAIR QAQKVYDLKGQISAKFETKLMEKDKAARVIEGHKSEIDIHPFERKPKGSPREYPDGDFVWAESRESFDGAIWWAG QTVNEEFQQLRETLESLAKETSRADKAREKAENTLLSATRGREQTVKIEAQDHQHNTANTAKIGPNTPKAPASSK DIITAGEQVEHLVDELPPPPRENPSRKKSAAEEKSRGSSSQPRLECCPVGKRGLLRRAACIPCPPTDSRGSSGRK NGNRENEQGRGMEKQATRNEAQSMKSEANGERNAKTSTDKNALGQIAKAPPPPKGDPSPPTEKDVLGQVAKAPPP PKGNPSALTEKEVLGQVAKAPPPPKGNPSAPTEKEVLSQIAKAPPPPERNPLPPTEKDVLGQIAKAPPPPKGNPS PKTSSSLQLKSLADSTSSREFSRLIEEFGLRLPKNAAGRTLAATELHTKFKANRPALSTLKASKWGSNVALTVTT LPWFIQDLNKMYKSDMTDLQKAAVLTSIVPLIRCSVGAAAEAEQGQVDIANLVVCYVSDALLLTPLFPIGIIIKA VQHIAAVFIKYHKLTSLSSLQSTRDEGWQAQYKGIKEFISSEEYLSQLRNQYTASKLAVLFALAGQRELLAARWV ELANTTQTKHHRDVQEIYEKLDAQWIKVRQETCADLRDIEHRFRTKIPNQMAGSLGTASIRYDKQFAYGYRQVTA LEKERMLKDGIPSWTRNRLANTYDENLQALWNTRRTRNSAAVKKEVNEIQRLAKDAASKFMQPDLALCEEPPEGL PKLPQFPVEFCEDFYFDGQCADETMYFPCSMLSRCPLLNYGSCADSRY*
Coding	>Hirsu2|8399 ATGTATGCCTGCTGGGTTCACTTTGTGCCATTATTGGTGATTCTTCTCCTTTGGCCGGCCTCTAGCTTTGCTTAT CCAACGGATTCTCAAAACCAACCAATAATCCTCTATCGTGGCGATACTCGAGCTCCGGAAGAAATCAAGTTCCAA GGGGGGTTTCTGCCGCCTATAAACCCTGCGCCGCACGACAAATATCGCATCACCGATCATATAAGGCTTGTAGCG GCCCCTTACGGCAAAGCTGCAACCCCTTACATCTCCACAACGCCTGATTTCATTTTCGCTTCCAAATTCGCCAAG GCCCGTGCAAGATATGGTGCCAAAGAGTCTTTCGTCTATCACGTTCACGCGACGCCGCATATCTTCAGAGCGGTT GATAGCGTAGACCAGGACCCTGTAACAAAGGGAGGCGCTGAGGGTGAATACGATGCGTTAGGCGGTATACCGTGG CGGCAAATCCTTGGCTGGACCCCTATCCCCTTGGACACCACGGGTGAATCGCTTATGGAGTATTTAGCTGCGGCA GATCAGTATTTCGTTCGCAACCGGGAATACGATACGAATTTCGATCAATATTCCGCAAGTGGCGGGCAACCTTTG CTCAACGAGCGAAACAAAGACCCAGCCCAGGGCAAAACGGCCTACGATTACGCCATAGATTTCATGAATAGGCCC GAAATCGGGGCTTGCGTGGGCTGGAAGGGCGAATTTCCCCTTTTCAAGACCCCCGACCATGACCAAAAACTTGCC GCGGCAAGACGGGCAAATGAAGAAGCTACCGAAGCAGCTCAAGGTGCCTTAGCCGCAGTTGACCGTGCGGAGGCC GCATTAAAGGATATCGAGAAGGCGCAAAGCCCGATGGACGCGCAGAAGTACGCCGAGATGGCCTGCATAGCAAGG GATCGTGCAGTCAAACTTGCTAGAGAAGTGGCTGCCAAAAGTGAGGAGTATATCATCATCAAATCAGACCTTTAC GAGGCAGCGATGGGTGCCATGAGGCGCGCAATCTCCGTAGCTGCCGTGGCTTCTAAGATAGGAAATATCAAAACA GCCAAGGACCACGCGAAGGAAGCCGAACGACTTGCTAAACTAAAAGATCAGGAGTCGGCGATTCAGGCAATAAGA CAGGCTCAAAAGGTCTACGACCTAAAAGGCCAAATTTCGGCGAAATTCGAAACCAAGCTCATGGAGAAAGACAAA GCGGCACGCGTGATAGAAGGGCACAAATCAGAGATAGACATCCATCCATTCGAACGAAAGCCTAAGGGATCGCCA AGGGAGTATCCTGATGGCGATTTCGTCTGGGCTGAAAGTCGAGAAAGCTTCGATGGTGCAATCTGGTGGGCGGGG CAGACCGTCAATGAGGAGTTTCAGCAACTGAGGGAGACGCTTGAGTCCCTTGCAAAGGAGACCTCCAGGGCCGAC AAGGCTCGAGAAAAGGCAGAAAATACGCTTCTCAGCGCGACGCGGGGAAGGGAACAGACAGTCAAGATTGAAGCT CAAGACCATCAACACAACACAGCCAACACAGCGAAAATAGGCCCAAACACCCCGAAAGCGCCTGCCTCGAGCAAA GACATAATCACAGCGGGTGAGCAAGTTGAGCACCTGGTCGACGAGTTACCACCACCACCCAGGGAGAATCCCTCA AGGAAGAAGTCCGCGGCTGAAGAAAAGAGCCGAGGTTCATCAAGTCAACCACGGCTAGAGTGTTGTCCTGTCGGT AAGAGAGGACTTTTACGGAGAGCGGCTTGCATCCCTTGCCCGCCTACAGACTCAAGAGGCTCAAGCGGCCGTAAG AATGGCAACAGAGAGAATGAACAGGGAAGAGGAATGGAGAAGCAAGCAACCAGGAACGAAGCACAATCAATGAAA TCAGAGGCCAATGGAGAGCGAAATGCAAAGACATCAACCGACAAGAATGCTTTAGGCCAAATCGCAAAAGCACCG CCACCACCCAAAGGGGATCCTTCGCCGCCAACTGAGAAGGATGTTTTAGGCCAAGTCGCAAAAGCACCGCCACCA CCTAAAGGGAATCCCTCGGCGCTGACCGAAAAGGAGGTTTTGGGCCAAGTCGCAAAGGCACCACCACCACCTAAA GGGAATCCCTCGGCGCCGACCGAAAAGGAGGTTTTGAGCCAAATAGCAAAGGCACCACCGCCACCCGAAAGGAAT CCCTTGCCGCCAACTGAGAAGGATGTTTTGGGCCAAATCGCGAAAGCACCGCCGCCACCCAAAGGGAACCCATCG CCCAAGACGTCGTCGTCTCTGCAGTTGAAGAGTTTAGCCGACAGCACATCGTCCAGAGAGTTTTCGAGGCTGATC GAGGAGTTCGGACTGCGGCTTCCGAAGAATGCTGCGGGCAGAACGCTGGCGGCAACTGAATTGCACACAAAATTT AAAGCGAATCGCCCAGCGCTGTCAACGCTCAAGGCGTCGAAGTGGGGTTCTAATGTGGCCTTGACTGTTACTACT CTGCCCTGGTTCATCCAAGACCTCAACAAAATGTATAAGTCGGACATGACGGACTTACAGAAAGCCGCAGTACTG ACATCGATCGTGCCTCTCATCCGCTGTTCAGTCGGAGCTGCGGCGGAAGCAGAGCAAGGCCAAGTAGATATCGCC AACCTCGTTGTCTGCTACGTCAGCGATGCCCTCTTACTTACGCCGCTATTTCCAATCGGTATCATCATAAAGGCT GTACAACATATTGCAGCAGTTTTTATCAAGTATCATAAGCTAACTAGTTTATCTTCCCTGCAAAGCACACGCGAC GAAGGGTGGCAGGCGCAATATAAAGGGATCAAAGAGTTTATTTCCTCCGAGGAATACCTTTCCCAACTGCGCAAT CAATATACGGCTAGCAAACTAGCTGTCCTGTTTGCGCTGGCAGGCCAACGCGAATTGTTAGCTGCCCGTTGGGTT GAGTTGGCAAATACTACGCAGACGAAACACCACAGGGACGTGCAGGAGATTTACGAGAAATTAGATGCACAGTGG ATAAAAGTTCGTCAAGAGACATGCGCGGACCTTCGGGACATAGAGCATCGGTTTAGGACGAAAATCCCGAACCAG ATGGCCGGTTCGTTGGGAACCGCAAGCATTCGATATGACAAACAATTTGCCTATGGGTACCGACAGGTCACGGCT CTCGAAAAGGAGCGAATGTTGAAAGATGGGATTCCATCCTGGACTAGAAACAGACTGGCGAATACATACGACGAA AATCTCCAGGCACTTTGGAATACCAGAAGGACTCGGAATTCAGCGGCGGTCAAGAAGGAGGTAAATGAAATCCAG AGACTCGCCAAGGACGCCGCAAGCAAGTTTATGCAGCCTGATCTGGCCTTATGCGAAGAGCCTCCTGAGGGTTTA CCGAAGCTCCCTCAGTTTCCCGTCGAGTTTTGCGAAGATTTCTACTTCGATGGGCAGTGCGCTGATGAGACCATG TATTTCCCGTGCAGTATGTTGTCTCGTTGCCCTCTACTCAACTACGGGTCTTGCGCTGACAGTCGTTACTAA
Transcript	>Hirsu2|8399 ATGTATGCCTGCTGGGTTCACTTTGTGCCATTATTGGTGATTCTTCTCCTTTGGCCGGCCTCTAGCTTTGCTTAT CCAACGGATTCTCAAAACCAACCAATAATCCTCTATCGTGGCGATACTCGAGCTCCGGAAGAAATCAAGTTCCAA GGGGGGTTTCTGCCGCCTATAAACCCTGCGCCGCACGACAAATATCGCATCACCGATCATATAAGGCTTGTAGCG GCCCCTTACGGCAAAGCTGCAACCCCTTACATCTCCACAACGCCTGATTTCATTTTCGCTTCCAAATTCGCCAAG GCCCGTGCAAGATATGGTGCCAAAGAGTCTTTCGTCTATCACGTTCACGCGACGCCGCATATCTTCAGAGCGGTT GATAGCGTAGACCAGGACCCTGTAACAAAGGGAGGCGCTGAGGGTGAATACGATGCGTTAGGCGGTATACCGTGG CGGCAAATCCTTGGCTGGACCCCTATCCCCTTGGACACCACGGGTGAATCGCTTATGGAGTATTTAGCTGCGGCA GATCAGTATTTCGTTCGCAACCGGGAATACGATACGAATTTCGATCAATATTCCGCAAGTGGCGGGCAACCTTTG CTCAACGAGCGAAACAAAGACCCAGCCCAGGGCAAAACGGCCTACGATTACGCCATAGATTTCATGAATAGGCCC GAAATCGGGGCTTGCGTGGGCTGGAAGGGCGAATTTCCCCTTTTCAAGACCCCCGACCATGACCAAAAACTTGCC GCGGCAAGACGGGCAAATGAAGAAGCTACCGAAGCAGCTCAAGGTGCCTTAGCCGCAGTTGACCGTGCGGAGGCC GCATTAAAGGATATCGAGAAGGCGCAAAGCCCGATGGACGCGCAGAAGTACGCCGAGATGGCCTGCATAGCAAGG GATCGTGCAGTCAAACTTGCTAGAGAAGTGGCTGCCAAAAGTGAGGAGTATATCATCATCAAATCAGACCTTTAC GAGGCAGCGATGGGTGCCATGAGGCGCGCAATCTCCGTAGCTGCCGTGGCTTCTAAGATAGGAAATATCAAAACA GCCAAGGACCACGCGAAGGAAGCCGAACGACTTGCTAAACTAAAAGATCAGGAGTCGGCGATTCAGGCAATAAGA CAGGCTCAAAAGGTCTACGACCTAAAAGGCCAAATTTCGGCGAAATTCGAAACCAAGCTCATGGAGAAAGACAAA GCGGCACGCGTGATAGAAGGGCACAAATCAGAGATAGACATCCATCCATTCGAACGAAAGCCTAAGGGATCGCCA AGGGAGTATCCTGATGGCGATTTCGTCTGGGCTGAAAGTCGAGAAAGCTTCGATGGTGCAATCTGGTGGGCGGGG CAGACCGTCAATGAGGAGTTTCAGCAACTGAGGGAGACGCTTGAGTCCCTTGCAAAGGAGACCTCCAGGGCCGAC AAGGCTCGAGAAAAGGCAGAAAATACGCTTCTCAGCGCGACGCGGGGAAGGGAACAGACAGTCAAGATTGAAGCT CAAGACCATCAACACAACACAGCCAACACAGCGAAAATAGGCCCAAACACCCCGAAAGCGCCTGCCTCGAGCAAA GACATAATCACAGCGGGTGAGCAAGTTGAGCACCTGGTCGACGAGTTACCACCACCACCCAGGGAGAATCCCTCA AGGAAGAAGTCCGCGGCTGAAGAAAAGAGCCGAGGTTCATCAAGTCAACCACGGCTAGAGTGTTGTCCTGTCGGT AAGAGAGGACTTTTACGGAGAGCGGCTTGCATCCCTTGCCCGCCTACAGACTCAAGAGGCTCAAGCGGCCGTAAG AATGGCAACAGAGAGAATGAACAGGGAAGAGGAATGGAGAAGCAAGCAACCAGGAACGAAGCACAATCAATGAAA TCAGAGGCCAATGGAGAGCGAAATGCAAAGACATCAACCGACAAGAATGCTTTAGGCCAAATCGCAAAAGCACCG CCACCACCCAAAGGGGATCCTTCGCCGCCAACTGAGAAGGATGTTTTAGGCCAAGTCGCAAAAGCACCGCCACCA CCTAAAGGGAATCCCTCGGCGCTGACCGAAAAGGAGGTTTTGGGCCAAGTCGCAAAGGCACCACCACCACCTAAA GGGAATCCCTCGGCGCCGACCGAAAAGGAGGTTTTGAGCCAAATAGCAAAGGCACCACCGCCACCCGAAAGGAAT CCCTTGCCGCCAACTGAGAAGGATGTTTTGGGCCAAATCGCGAAAGCACCGCCGCCACCCAAAGGGAACCCATCG CCCAAGACGTCGTCGTCTCTGCAGTTGAAGAGTTTAGCCGACAGCACATCGTCCAGAGAGTTTTCGAGGCTGATC GAGGAGTTCGGACTGCGGCTTCCGAAGAATGCTGCGGGCAGAACGCTGGCGGCAACTGAATTGCACACAAAATTT AAAGCGAATCGCCCAGCGCTGTCAACGCTCAAGGCGTCGAAGTGGGGTTCTAATGTGGCCTTGACTGTTACTACT CTGCCCTGGTTCATCCAAGACCTCAACAAAATGTATAAGTCGGACATGACGGACTTACAGAAAGCCGCAGTACTG ACATCGATCGTGCCTCTCATCCGCTGTTCAGTCGGAGCTGCGGCGGAAGCAGAGCAAGGCCAAGTAGATATCGCC AACCTCGTTGTCTGCTACGTCAGCGATGCCCTCTTACTTACGCCGCTATTTCCAATCGGTATCATCATAAAGGCT GTACAACATATTGCAGCAGTTTTTATCAAGTATCATAAGCTAACTAGTTTATCTTCCCTGCAAAGCACACGCGAC GAAGGGTGGCAGGCGCAATATAAAGGGATCAAAGAGTTTATTTCCTCCGAGGAATACCTTTCCCAACTGCGCAAT CAATATACGGCTAGCAAACTAGCTGTCCTGTTTGCGCTGGCAGGCCAACGCGAATTGTTAGCTGCCCGTTGGGTT GAGTTGGCAAATACTACGCAGACGAAACACCACAGGGACGTGCAGGAGATTTACGAGAAATTAGATGCACAGTGG ATAAAAGTTCGTCAAGAGACATGCGCGGACCTTCGGGACATAGAGCATCGGTTTAGGACGAAAATCCCGAACCAG ATGGCCGGTTCGTTGGGAACCGCAAGCATTCGATATGACAAACAATTTGCCTATGGGTACCGACAGGTCACGGCT CTCGAAAAGGAGCGAATGTTGAAAGATGGGATTCCATCCTGGACTAGAAACAGACTGGCGAATACATACGACGAA AATCTCCAGGCACTTTGGAATACCAGAAGGACTCGGAATTCAGCGGCGGTCAAGAAGGAGGTAAATGAAATCCAG AGACTCGCCAAGGACGCCGCAAGCAAGTTTATGCAGCCTGATCTGGCCTTATGCGAAGAGCCTCCTGAGGGTTTA CCGAAGCTCCCTCAGTTTCCCGTCGAGTTTTGCGAAGATTTCTACTTCGATGGGCAGTGCGCTGATGAGACCATG TATTTCCCGTGCAGTATGTTGTCTCGTTGCCCTCTACTCAACTACGGGTCTTGCGCTGACAGTCGTTACTAA
Gene	>Hirsu2|8399 ATGTATGCCTGCTGGGTTCACTTTGTGCCATTATTGGTGATTCTTCTCCTTTGGCCGGCCTCTAGCTTTGCTTAT CCAACGGATTCTCAAAACCAACCAATAATCCTCTATCGTGGCGATACTCGAGCTCCGGAAGAAATCAAGTTCCAA GGGGGGTTTCTGCCGCCTATAAACCCTGCGCCGCACGACAAATATCGCATCACCGATCATATAAGGCTTGTAGCG GCCCCTTACGGCAAAGCTGCAACCCCTTACATCTCCACAACGCCTGATTTCATTTTCGCTTCCAAATTCGCCAAG GCCCGTGCAAGATATGGTGCCAAAGAGTCTTTCGTCTATCACGTTCACGCGACGCCGCATATCTTCAGAGCGGTT GATAGCGTAGACCAGGACCCTGTAACAAAGGGAGGCGCTGAGGGTGAATACGATGCGTTAGGCGGTATACCGTGG CGGCAAATCCTTGGCTGGACCCCTATCCCCTTGGACACCACGGGTGAATCGCTTATGGAGTATTTAGCTGCGGCA GATCAGTATTTCGTTCGCAACCGGGAATACGATACGAATTTCGATCAATATTCCGCAAGTGGCGGGCAACCTTTG CTCAACGAGCGAAACAAAGACCCAGCCCAGGGCAAAACGGCCTACGATTACGCCATAGATTTCATGAATAGGCCC GAAATCGGGGCTTGCGTGGGCTGGAAGGGCGAATTTCCCCTTTTCAAGACCCCCGACCATGACCAAAAACTTGCC GCGGCAAGACGGGCAAATGAAGAAGCTACCGAAGCAGCTCAAGGTGCCTTAGCCGCAGTTGACCGTGCGGAGGCC GCATTAAAGGATATCGAGAAGGCGCAAAGCCCGATGGACGCGCAGAAGTACGCCGAGATGGCCTGCATAGCAAGG GATCGTGCAGTCAAACTTGCTAGAGAAGTGGCTGCCAAAAGTGAGGAGTATATCATCATCAAATCAGACCTTTAC GAGGCAGCGATGGGTGCCATGAGGCGCGCAATCTCCGTAGCTGCCGTGGCTTCTAAGATAGGAAATATCAAAACA GCCAAGGACCACGCGAAGGAAGCCGAACGACTTGCTAAACTAAAAGATCAGGAGTCGGCGATTCAGGCAATAAGA CAGGCTCAAAAGGTCTACGACCTAAAAGGCCAAATTTCGGCGAAATTCGAAACCAAGCTCATGGAGAAAGACAAA GCGGCACGCGTGATAGAAGGGCACAAATCAGAGATAGACATCCATCCATTCGAACGAAAGCCTAAGGGATCGCCA AGGGAGTATCCTGATGGCGATTTCGTCTGGGCTGAAAGTCGAGAAAGCTTCGATGGTGCAATCTGGTGGGCGGGG CAGACCGTCAATGAGGAGTTTCAGCAACTGAGGGAGACGCTTGAGTCCCTTGCAAAGGAGACCTCCAGGGCCGAC AAGGCTCGAGAAAAGGCAGAAAATACGCTTCTCAGCGCGACGCGGGGAAGGGAACAGACAGTCAAGATTGAAGCT CAAGACCATCAACACAACACAGCCAACACAGCGAAAATAGGCCCAAACACCCCGAAAGCGCCTGCCTCGAGCAAA GACATAATCACAGCGGGTGAGCAAGTTGAGCACCTGGTCGACGAGTTACCACCACCACCCAGGGAGAATCCCTCA AGGAAGAAGTCCGCGGCTGAAGAAAAGAGCCGAGGTTCATCAAGTCAACCACGGCTAGAGTGTTGTCCTGTCGGT AAGAGAGGACTTTTACGGAGAGCGGCTTGCATCCCTTGCCCGCCTACAGACTCAAGAGGCTCAAGCGGCCGTAAG AATGGCAACAGAGAGAATGAACAGGGAAGAGGAATGGAGAAGCAAGCAACCAGGAACGAAGCACAATCAATGAAA TCAGAGGCCAATGGAGAGCGAAATGCAAAGACATCAACCGACAAGAATGCTTTAGGCCAAATCGCAAAAGCACCG CCACCACCCAAAGGGGATCCTTCGCCGCCAACTGAGAAGGATGTTTTAGGCCAAGTCGCAAAAGCACCGCCACCA CCTAAAGGGAATCCCTCGGCGCTGACCGAAAAGGAGGTTTTGGGCCAAGTCGCAAAGGCACCACCACCACCTAAA GGGAATCCCTCGGCGCCGACCGAAAAGGAGGTTTTGAGCCAAATAGCAAAGGCACCACCGCCACCCGAAAGGAAT CCCTTGCCGCCAACTGAGAAGGATGTTTTGGGCCAAATCGCGAAAGCACCGCCGCCACCCAAAGGGAACCCATCG CCCAAGACGTCGTCGTCTCTGCAGTTGAAGAGTTTAGCCGACAGCACATCGTCCAGAGAGTTTTCGAGGCTGATC GAGGAGTTCGGACTGCGGCTTCCGAAGAATGCTGCGGGCAGAACGCTGGCGGCAACTGAATTGCACACAAAATTT AAAGCGAATCGCCCAGCGCTGTCAACGCTCAAGGCGTCGAAGTGGGGTTCTAATGTGGCCTTGACTGTTACTACT CTGCCCTGGTTCATCCAAGACCTCAACAAAATGTATAAGTCGGACATGACGGACTTACAGAAAGCCGCAGTACTG ACATCGATCGTGCCTCTCATCCGCTGTTCAGTCGGAGCTGCGGCGGAAGCAGAGCAAGGCCAAGTAGATATCGCC AACCTCGTTGTCTGCTACGTCAGCGATGCCCTCTTACTTACGCCGCTATTTCCAATCGGTATCATCATAAAGGCT GTACAACATATTGCAGCAGTTTTTATCAAGTATCATAAGCTAACTAGTTTATCTTCCCTGCAAAGCACACGCGAC GAAGGGTGGCAGGCGCAATATAAAGGGATCAAAGAGTTTATTTCCTCCGAGGAATACCTTTCCCAACTGCGCAAT CAATATACGGCTAGCAAACTAGCTGTCCTGTTTGCGCTGGCAGGCCAACGCGAATTGTTAGCTGCCCGTTGGGTT GAGTTGGCAAATACTACGCAGACGAAACACCACAGGGACGTGCAGGAGATTTACGAGAAATTAGATGCACAGTGG ATAAAAGTTCGTCAAGAGACATGCGCGGACCTTCGGGACATAGAGCATCGGTTTAGGACGAAAATCCCGAACCAG ATGGCCGGTTCGTTGGGAACCGCAAGCATTCGATATGACAAACAATTTGCCTATGGGTACCGACAGGTCACGGCT CTCGAAAAGGAGCGAATGTTGAAAGATGGGATTCCATCCTGGACTAGAAACAGACTGGCGAATACATACGACGAA AATCTCCAGGCACTTTGGAATACCAGAAGGACTCGGAATTCAGCGGCGGTCAAGAAGGAGGTAAATGAAATCCAG AGACTCGCCAAGGACGCCGCAAGCAAGTTTATGCAGCCTGATCTGGCCTTATGCGAAGAGCCTCCTGAGGGTTTA CCGAAGCTCCCTCAGTTTCCCGTCGAGTTTTGCGAAGATTTCTACTTCGATGGGCAGTGCGCTGATGAGACCATG TATTTCCCGTGCAGTATGTTGTCTCGTTGCCCTCTACTCAACTACGGGTCTTGCGCTGACAGTCGTTACTAA