© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|7721 |
| Gene name | |
| Location | Contig_465:12721..17003 |
| Strand | - |
| Gene length (bp) | 4282 |
| Transcript length (bp) | 4161 |
| Coding sequence length (bp) | 4161 |
| Protein length (aa) | 1387 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF14664 | RICTOR_N | Rapamycin-insensitive companion of mTOR, N-term | 9.4E-134 | 245 | 622 |
| PF14666 | RICTOR_M | Rapamycin-insensitive companion of mTOR, middle domain | 1.2E-35 | 821 | 921 |
| PF14663 | RasGEF_N_2 | Rapamycin-insensitive companion of mTOR RasGEF_N domain | 1.3E-34 | 939 | 1042 |
| PF14668 | RICTOR_V | Rapamycin-insensitive companion of mTOR, domain 5 | 3.4E-28 | 1116 | 1185 |
| PF02185 | HR1 | Hr1 repeat | 1.8E-15 | 114 | 178 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q09743|STE16_SCHPO | Protein ste16 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ste16 PE=3 SV=1 | 245 | 1326 | 0.0E+00 |
| sp|O77203|PIAA_DICDI | Protein pianissimo A OS=Dictyostelium discoideum GN=piaA PE=1 SV=1 | 231 | 1322 | 5.0E-114 |
| sp|P40061|TSC11_YEAST | Target of rapamycin complex 2 subunit TSC11 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC11 PE=1 SV=1 | 221 | 1208 | 3.0E-113 |
| sp|Q6QI06|RICTR_MOUSE | Rapamycin-insensitive companion of mTOR OS=Mus musculus GN=Rictor PE=1 SV=2 | 218 | 1206 | 5.0E-108 |
| sp|Q6R327|RICTR_HUMAN | Rapamycin-insensitive companion of mTOR OS=Homo sapiens GN=RICTOR PE=1 SV=1 | 218 | 1206 | 2.0E-107 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0007165 | signal transduction | Yes |
| GO:0009987 | cellular process | No |
| GO:0050789 | regulation of biological process | No |
| GO:0008150 | biological_process | No |
| GO:0065007 | biological regulation | No |
| GO:0050794 | regulation of cellular process | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 31 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|7721 MPAPSSQQNAHHHNQQQQQQQQPGRSSFDRDAGALQLPPNGGPPRKMSAPAMSFAPRGSGLNPNPGPGSFSSELR SQMLSSRAGSRVDIGSSFSAGAPDKVEDDGSAAAMEQALSVLRERLNREMKIKEGSENMLEALNIKKAKQTKEQR QRVEAELSASNSRIKELRQKILDAQRSKPVPPSTPTRNRTHDGLLLSSGHLRSPPSISRSAMGSDIDEMMESPTF LLAEFLQALEVEGMAPEYYVSRANQLVELFKRHPAIKYDLVWSIFGLRMQMMLLSESREVVAAGYRATRYAMTDV ASLKKIRNLNTDYLVIRSLNNYRKADVEREQALKFVRAFLDVKDGVREISRAVVRTIVAVAEQGEERRPGGANVA DHNIDRLRPICIETLAEILVGDPQLLIASGGLGPLSEALGEGTYKAPESLMSAFLFLLDTPGKRKYIQPGYGLDV VFTAFTDQLAGAESILKQNSRAISVAMKSWSGLMTLGMYDFRPIRSLIASILFPNSAIRETVLDLLFSLLRIKPP AWATSFLAGRRLTTYGRVANMKSTNGRERSATLSLEEDSGEQNFVDHYTALLLAVFIQAGLLQRLLQIAQSEEDS MLKRKTTLLIGEVLKLASRLLPPAWSAELQLLPELFSAAAQFGNEAHFVASGIVYQISSVSRTLYRSAPSESMAG ALPSSDSMQHLAMFEEHPKANAAMVFDDATFRQLLIDTGVLNSSNYLKWNWEVIIKVIDGPLQIGKRLEEAIRAS KFMKRIMSFYRPFKYKFAEIKNTRNTQKYVRAGCALVHSLLQSTEGVRVLADSKLLRQIAECLAQCDPTSGLTAQ FPMFAKDRLTDTLCGGYFPMLGVLSSYSQGLLLLERWRMFNMMYHIVDLKQRPDLIKLLLSNFDYSLQGHPRVLL SKALIAGNKNIRIHATNTLRKCTMRPVTSLSGQGNASDAKWAIQLLVTQLYDPEIEVCSTAVKILENACNRKVFL EYIVECRPALDHLGEIGAPLLLRFLSTSIGYHYLDGLDYISNEMDDWFLGRNDSYVDVIEASLARAFLAGPDDHG HRVSLFNEAEAETDFHDSHVPPHFYRELTRTREGCKLLSDKGHFEEFVATIRDHGMQTEDGELMTKVKGCLWAVG NVGSMELGAPFLEASDVVERIIDIAESHEVMSLRGTAFFVLGLISRSTHGLEILSEHGWDANTTSMGASLGFCIP NDLSRLFSMRPWQHVKAASIKLLDTQRTAREQPSVRQARPPLEPSEMPPLVSEADINERIMELVVDLGNMVLYKK AVGELQKLKTRKPNAFRSTDFFKKVMGLMEWNHYRLGVRRLVIDLFEKHVMRQIVFGEDEGSGGGNGDVGPAGDD SGDGSSGDDRTERQRSISEPAEMPSDLMPAPLKVRR* |
| Coding | >Hirsu2|7721 ATGCCCGCCCCATCCTCCCAGCAGAATGCCCACCATCACAACCAGCAGCAGCAGCAGCAGCAGCAGCCCGGCCGA TCCAGCTTCGACCGCGATGCCGGCGCTCTGCAGCTCCCTCCCAATGGCGGCCCGCCACGCAAGATGTCCGCCCCT GCCATGTCCTTTGCGCCCCGCGGCAGCGGCCTGAACCCCAACCCGGGTCCGGGCAGCTTCAGCTCCGAACTGCGA AGCCAGATGCTCTCGAGCCGTGCCGGCAGCCGCGTCGACATAGGCTCCTCATTCTCTGCTGGCGCCCCCGACAAG GTGGAAGACGACGGCTCCGCGGCCGCCATGGAGCAAGCCTTGTCTGTGCTCAGGGAGAGGCTGAACCGAGAGATG AAGATCAAGGAGGGTAGCGAAAACATGCTCGAGGCGCTGAACATTAAGAAGGCCAAGCAGACCAAGGAGCAGCGG CAAAGAGTCGAGGCAGAGCTGAGCGCCAGCAATTCCAGGATTAAGGAGCTGCGGCAAAAGATTTTGGACGCTCAG CGCTCCAAGCCGGTCCCTCCATCCACCCCGACCAGAAATCGGACCCATGATGGCCTGCTGCTGTCTAGCGGACAC CTGCGCTCGCCCCCTAGCATCTCGCGCTCCGCCATGGGCTCCGACATAGACGAGATGATGGAGAGCCCAACCTTC TTGCTGGCCGAGTTCCTGCAGGCTCTCGAGGTCGAGGGCATGGCACCCGAGTACTATGTGAGCAGGGCCAACCAG CTGGTCGAACTCTTCAAGCGACACCCGGCCATCAAGTACGACCTCGTCTGGTCCATCTTCGGGCTGCGCATGCAA ATGATGTTGCTCAGCGAGAGCCGCGAGGTCGTCGCTGCTGGCTACCGAGCCACTCGATACGCCATGACGGACGTG GCCTCCTTAAAAAAGATCCGCAACCTCAACACTGATTATCTAGTGATAAGGTCGCTCAACAACTATCGCAAAGCC GACGTGGAACGCGAGCAGGCTCTCAAGTTCGTGCGGGCCTTCCTTGACGTCAAGGACGGCGTCAGGGAAATCTCT CGGGCCGTAGTGCGCACCATTGTCGCGGTCGCCGAGCAGGGTGAGGAACGTCGCCCCGGCGGCGCTAATGTCGCC GACCACAATATTGATCGGCTGCGCCCAATATGCATCGAGACGCTCGCAGAAATACTGGTGGGCGATCCGCAGCTC CTCATTGCATCGGGCGGCCTTGGGCCCCTCTCGGAAGCTTTGGGCGAGGGCACATACAAGGCCCCGGAGAGCTTG ATGTCTGCTTTCCTCTTCCTCCTCGACACGCCCGGCAAACGCAAATACATTCAGCCCGGCTACGGCTTGGACGTC GTGTTTACCGCCTTCACCGACCAGCTCGCCGGGGCGGAGAGCATTCTCAAACAGAACTCCAGAGCCATATCCGTT GCCATGAAGTCGTGGTCCGGCCTGATGACCCTTGGCATGTACGATTTTCGGCCGATCCGTTCGCTCATCGCGAGC ATATTGTTTCCCAACTCAGCAATACGCGAGACTGTTCTGGACCTGCTGTTCTCCCTGCTGCGGATCAAGCCACCT GCCTGGGCCACATCATTCTTAGCCGGACGCCGGTTGACGACATACGGGAGAGTGGCCAATATGAAGTCGACCAAC GGCAGGGAAAGGAGCGCCACGCTCTCCCTGGAAGAGGACAGCGGCGAGCAGAACTTTGTCGATCACTACACGGCG CTGCTGCTGGCCGTCTTCATTCAGGCGGGGCTGCTGCAAAGACTGCTGCAGATAGCGCAGTCAGAAGAAGACTCG ATGCTGAAGCGCAAAACGACACTGCTGATCGGCGAGGTGCTGAAGCTGGCCAGCCGATTACTCCCTCCCGCATGG AGCGCCGAGCTGCAGCTTCTGCCGGAGCTGTTCTCGGCGGCCGCACAGTTCGGCAACGAGGCTCACTTTGTGGCG TCGGGCATCGTCTACCAGATCAGCAGCGTCAGTAGGACGCTGTACAGGAGCGCCCCGTCCGAGTCCATGGCCGGC GCCCTGCCATCCAGCGACAGCATGCAACACCTGGCAATGTTCGAGGAACACCCCAAGGCCAACGCGGCCATGGTC TTCGACGATGCAACGTTCCGCCAGCTCCTCATCGACACGGGCGTCCTCAACAGTTCCAACTACTTGAAGTGGAAC TGGGAGGTCATCATCAAGGTCATAGACGGGCCCTTGCAGATCGGGAAGCGGCTGGAAGAGGCCATCAGGGCTTCG AAGTTCATGAAGCGCATCATGAGCTTCTACAGGCCCTTCAAGTACAAGTTCGCCGAGATCAAGAACACGAGGAAC ACGCAGAAGTACGTCAGAGCCGGCTGTGCGCTGGTGCATTCTCTGCTCCAGTCGACCGAGGGTGTAAGGGTCTTG GCGGACAGCAAGCTGCTGAGACAGATCGCCGAGTGTCTTGCCCAGTGCGATCCGACCAGCGGCCTCACCGCGCAG TTTCCCATGTTTGCAAAGGACCGACTCACGGACACGCTCTGTGGAGGCTACTTCCCCATGCTTGGCGTCCTCAGC AGCTACTCCCAGGGGTTGCTTCTACTGGAGAGGTGGAGGATGTTCAACATGATGTACCATATCGTCGACCTGAAG CAGCGGCCCGATCTCATCAAGCTCCTCCTGTCTAACTTTGACTACAGCCTTCAGGGCCACCCCCGAGTCCTACTT TCCAAGGCCCTGATCGCGGGCAACAAGAACATTCGAATACACGCGACGAACACACTGCGCAAGTGTACAATGAGG CCGGTAACCTCGCTCAGCGGCCAGGGCAACGCTAGCGACGCGAAGTGGGCCATTCAGCTCCTCGTCACGCAGCTA TACGATCCAGAAATCGAGGTCTGCTCCACGGCCGTCAAGATTCTCGAGAACGCGTGCAACCGAAAGGTCTTCCTG GAATACATCGTCGAGTGTCGGCCCGCCCTCGACCACCTGGGCGAGATCGGGGCACCCCTGCTGCTGCGGTTCTTG TCCACCTCGATCGGTTATCACTACCTGGACGGGCTGGACTACATCAGCAATGAGATGGACGACTGGTTTCTGGGC CGGAACGACTCGTACGTCGACGTCATCGAGGCCAGTCTGGCGAGAGCCTTCCTGGCCGGCCCCGACGATCACGGC CACCGCGTCAGCCTATTCAACGAGGCGGAGGCGGAGACGGACTTTCACGACAGCCACGTGCCGCCGCACTTCTAC CGAGAGCTCACCCGCACGCGCGAGGGCTGCAAGCTCTTGAGCGATAAGGGCCACTTCGAGGAGTTCGTGGCGACG ATCCGCGATCACGGCATGCAGACCGAGGACGGCGAGCTGATGACCAAGGTCAAGGGCTGTCTTTGGGCAGTGGGC AACGTGGGGTCGATGGAGCTCGGGGCGCCGTTCCTGGAAGCGAGCGACGTGGTCGAGCGTATCATCGACATCGCC GAGTCGCACGAAGTCATGAGTCTGCGCGGCACGGCCTTCTTCGTGCTGGGGCTCATCTCGCGCTCCACCCACGGC CTGGAGATCCTGTCGGAACACGGATGGGACGCGAACACGACATCGATGGGGGCGTCACTCGGCTTTTGCATCCCC AACGACCTGTCGAGGCTTTTTTCGATGAGGCCTTGGCAGCACGTCAAGGCCGCGTCCATCAAGCTGCTCGACACG CAACGGACCGCGCGGGAGCAGCCGTCGGTCCGACAGGCGCGCCCGCCACTGGAGCCGTCAGAGATGCCGCCGCTC GTCAGTGAGGCGGACATCAATGAACGCATTATGGAGTTGGTGGTGGACTTGGGTAACATGGTGCTGTACAAGAAG GCGGTGGGCGAGCTGCAGAAGCTCAAGACGCGCAAGCCGAACGCGTTCCGCAGCACTGATTTCTTCAAGAAGGTG ATGGGTCTGATGGAGTGGAACCACTACCGGCTCGGGGTACGGAGGCTCGTGATTGACCTGTTCGAGAAGCACGTG ATGCGACAGATCGTGTTTGGCGAGGACGAAGGCAGCGGCGGCGGCAACGGAGATGTTGGGCCAGCGGGAGACGAC AGCGGCGACGGCAGCTCCGGGGACGACCGGACAGAGAGGCAGAGGAGCATCAGTGAGCCGGCGGAGATGCCGTCG GATCTAATGCCGGCGCCGCTCAAAGTACGGCGCTGA |
| Transcript | >Hirsu2|7721 ATGCCCGCCCCATCCTCCCAGCAGAATGCCCACCATCACAACCAGCAGCAGCAGCAGCAGCAGCAGCCCGGCCGA TCCAGCTTCGACCGCGATGCCGGCGCTCTGCAGCTCCCTCCCAATGGCGGCCCGCCACGCAAGATGTCCGCCCCT GCCATGTCCTTTGCGCCCCGCGGCAGCGGCCTGAACCCCAACCCGGGTCCGGGCAGCTTCAGCTCCGAACTGCGA AGCCAGATGCTCTCGAGCCGTGCCGGCAGCCGCGTCGACATAGGCTCCTCATTCTCTGCTGGCGCCCCCGACAAG GTGGAAGACGACGGCTCCGCGGCCGCCATGGAGCAAGCCTTGTCTGTGCTCAGGGAGAGGCTGAACCGAGAGATG AAGATCAAGGAGGGTAGCGAAAACATGCTCGAGGCGCTGAACATTAAGAAGGCCAAGCAGACCAAGGAGCAGCGG CAAAGAGTCGAGGCAGAGCTGAGCGCCAGCAATTCCAGGATTAAGGAGCTGCGGCAAAAGATTTTGGACGCTCAG CGCTCCAAGCCGGTCCCTCCATCCACCCCGACCAGAAATCGGACCCATGATGGCCTGCTGCTGTCTAGCGGACAC CTGCGCTCGCCCCCTAGCATCTCGCGCTCCGCCATGGGCTCCGACATAGACGAGATGATGGAGAGCCCAACCTTC TTGCTGGCCGAGTTCCTGCAGGCTCTCGAGGTCGAGGGCATGGCACCCGAGTACTATGTGAGCAGGGCCAACCAG CTGGTCGAACTCTTCAAGCGACACCCGGCCATCAAGTACGACCTCGTCTGGTCCATCTTCGGGCTGCGCATGCAA ATGATGTTGCTCAGCGAGAGCCGCGAGGTCGTCGCTGCTGGCTACCGAGCCACTCGATACGCCATGACGGACGTG GCCTCCTTAAAAAAGATCCGCAACCTCAACACTGATTATCTAGTGATAAGGTCGCTCAACAACTATCGCAAAGCC GACGTGGAACGCGAGCAGGCTCTCAAGTTCGTGCGGGCCTTCCTTGACGTCAAGGACGGCGTCAGGGAAATCTCT CGGGCCGTAGTGCGCACCATTGTCGCGGTCGCCGAGCAGGGTGAGGAACGTCGCCCCGGCGGCGCTAATGTCGCC GACCACAATATTGATCGGCTGCGCCCAATATGCATCGAGACGCTCGCAGAAATACTGGTGGGCGATCCGCAGCTC CTCATTGCATCGGGCGGCCTTGGGCCCCTCTCGGAAGCTTTGGGCGAGGGCACATACAAGGCCCCGGAGAGCTTG ATGTCTGCTTTCCTCTTCCTCCTCGACACGCCCGGCAAACGCAAATACATTCAGCCCGGCTACGGCTTGGACGTC GTGTTTACCGCCTTCACCGACCAGCTCGCCGGGGCGGAGAGCATTCTCAAACAGAACTCCAGAGCCATATCCGTT GCCATGAAGTCGTGGTCCGGCCTGATGACCCTTGGCATGTACGATTTTCGGCCGATCCGTTCGCTCATCGCGAGC ATATTGTTTCCCAACTCAGCAATACGCGAGACTGTTCTGGACCTGCTGTTCTCCCTGCTGCGGATCAAGCCACCT GCCTGGGCCACATCATTCTTAGCCGGACGCCGGTTGACGACATACGGGAGAGTGGCCAATATGAAGTCGACCAAC GGCAGGGAAAGGAGCGCCACGCTCTCCCTGGAAGAGGACAGCGGCGAGCAGAACTTTGTCGATCACTACACGGCG CTGCTGCTGGCCGTCTTCATTCAGGCGGGGCTGCTGCAAAGACTGCTGCAGATAGCGCAGTCAGAAGAAGACTCG ATGCTGAAGCGCAAAACGACACTGCTGATCGGCGAGGTGCTGAAGCTGGCCAGCCGATTACTCCCTCCCGCATGG AGCGCCGAGCTGCAGCTTCTGCCGGAGCTGTTCTCGGCGGCCGCACAGTTCGGCAACGAGGCTCACTTTGTGGCG TCGGGCATCGTCTACCAGATCAGCAGCGTCAGTAGGACGCTGTACAGGAGCGCCCCGTCCGAGTCCATGGCCGGC GCCCTGCCATCCAGCGACAGCATGCAACACCTGGCAATGTTCGAGGAACACCCCAAGGCCAACGCGGCCATGGTC TTCGACGATGCAACGTTCCGCCAGCTCCTCATCGACACGGGCGTCCTCAACAGTTCCAACTACTTGAAGTGGAAC TGGGAGGTCATCATCAAGGTCATAGACGGGCCCTTGCAGATCGGGAAGCGGCTGGAAGAGGCCATCAGGGCTTCG AAGTTCATGAAGCGCATCATGAGCTTCTACAGGCCCTTCAAGTACAAGTTCGCCGAGATCAAGAACACGAGGAAC ACGCAGAAGTACGTCAGAGCCGGCTGTGCGCTGGTGCATTCTCTGCTCCAGTCGACCGAGGGTGTAAGGGTCTTG GCGGACAGCAAGCTGCTGAGACAGATCGCCGAGTGTCTTGCCCAGTGCGATCCGACCAGCGGCCTCACCGCGCAG TTTCCCATGTTTGCAAAGGACCGACTCACGGACACGCTCTGTGGAGGCTACTTCCCCATGCTTGGCGTCCTCAGC AGCTACTCCCAGGGGTTGCTTCTACTGGAGAGGTGGAGGATGTTCAACATGATGTACCATATCGTCGACCTGAAG CAGCGGCCCGATCTCATCAAGCTCCTCCTGTCTAACTTTGACTACAGCCTTCAGGGCCACCCCCGAGTCCTACTT TCCAAGGCCCTGATCGCGGGCAACAAGAACATTCGAATACACGCGACGAACACACTGCGCAAGTGTACAATGAGG CCGGTAACCTCGCTCAGCGGCCAGGGCAACGCTAGCGACGCGAAGTGGGCCATTCAGCTCCTCGTCACGCAGCTA TACGATCCAGAAATCGAGGTCTGCTCCACGGCCGTCAAGATTCTCGAGAACGCGTGCAACCGAAAGGTCTTCCTG GAATACATCGTCGAGTGTCGGCCCGCCCTCGACCACCTGGGCGAGATCGGGGCACCCCTGCTGCTGCGGTTCTTG TCCACCTCGATCGGTTATCACTACCTGGACGGGCTGGACTACATCAGCAATGAGATGGACGACTGGTTTCTGGGC CGGAACGACTCGTACGTCGACGTCATCGAGGCCAGTCTGGCGAGAGCCTTCCTGGCCGGCCCCGACGATCACGGC CACCGCGTCAGCCTATTCAACGAGGCGGAGGCGGAGACGGACTTTCACGACAGCCACGTGCCGCCGCACTTCTAC CGAGAGCTCACCCGCACGCGCGAGGGCTGCAAGCTCTTGAGCGATAAGGGCCACTTCGAGGAGTTCGTGGCGACG ATCCGCGATCACGGCATGCAGACCGAGGACGGCGAGCTGATGACCAAGGTCAAGGGCTGTCTTTGGGCAGTGGGC AACGTGGGGTCGATGGAGCTCGGGGCGCCGTTCCTGGAAGCGAGCGACGTGGTCGAGCGTATCATCGACATCGCC GAGTCGCACGAAGTCATGAGTCTGCGCGGCACGGCCTTCTTCGTGCTGGGGCTCATCTCGCGCTCCACCCACGGC CTGGAGATCCTGTCGGAACACGGATGGGACGCGAACACGACATCGATGGGGGCGTCACTCGGCTTTTGCATCCCC AACGACCTGTCGAGGCTTTTTTCGATGAGGCCTTGGCAGCACGTCAAGGCCGCGTCCATCAAGCTGCTCGACACG CAACGGACCGCGCGGGAGCAGCCGTCGGTCCGACAGGCGCGCCCGCCACTGGAGCCGTCAGAGATGCCGCCGCTC GTCAGTGAGGCGGACATCAATGAACGCATTATGGAGTTGGTGGTGGACTTGGGTAACATGGTGCTGTACAAGAAG GCGGTGGGCGAGCTGCAGAAGCTCAAGACGCGCAAGCCGAACGCGTTCCGCAGCACTGATTTCTTCAAGAAGGTG ATGGGTCTGATGGAGTGGAACCACTACCGGCTCGGGGTACGGAGGCTCGTGATTGACCTGTTCGAGAAGCACGTG ATGCGACAGATCGTGTTTGGCGAGGACGAAGGCAGCGGCGGCGGCAACGGAGATGTTGGGCCAGCGGGAGACGAC AGCGGCGACGGCAGCTCCGGGGACGACCGGACAGAGAGGCAGAGGAGCATCAGTGAGCCGGCGGAGATGCCGTCG GATCTAATGCCGGCGCCGCTCAAAGTACGGCGCTGA |
| Gene | >Hirsu2|7721 ATGCCCGCCCCATCCTCCCAGCAGAATGCCCACCATCACAACCAGCAGCAGCAGCAGCAGCAGCAGCCCGGCCGA TCCAGCTTCGACCGCGATGCCGGCGCTCTGCAGCTCCCTCCCAATGGCGGCCCGCCACGCAAGATGTCCGCCCCT GCCATGTCCTTTGCGCCCCGCGGCAGCGGCCTGAACCCCAACCCGGGTCCGGGCAGCTTCAGCTCCGAACTGCGA AGCCAGATGCTCTCGAGCCGTGCCGGCAGCCGCGTCGACATAGGCTCCTCATTCTCTGCTGGCGCCCCCGACAAG GTGGAAGACGACGGCTCCGCGGCCGCCATGGAGCAAGCCTTGTCTGTGCTCAGGGAGAGGCTGAACCGAGAGATG AAGATCAAGGAGGGTAGCGAAAACATGCTCGAGGCGCTGAACATTAAGAAGGCCAAGCAGACCAAGGAGCAGCGG CAAAGAGTCGAGGCAGAGCTGAGCGCCAGCAATTCCAGGATTAAGGAGCTGCGGCAAAAGATTTTGGACGCTCAG CGCTCCAAGCCGGTCCCTCCATCCACCCCGACCAGAAATCGGACCCATGATGGCCTGCTGCTGTCTAGCGGACAC CTGCGCTCGCCCCCTAGCATCTCGCGCTCCGCCATGGGCTCCGACATAGACGAGATGATGGAGAGCCCAACCTTC TTGCTGGCCGAGTTCCTGCAGGCTCTCGAGGTCGAGGGCATGGCACCCGAGTACTATGTGAGCAGGGCCAACCAG CTGGTCGAACTCTTCAAGCGACACCCGGCCATCAAGTACGACCTCGTCTGGTCCATCTTCGGGCTGCGCATGCAA ATGATGTTGCTCAGCGAGAGCCGCGAGGTCGTCGCTGCTGGCTACCGAGCCACTCGATACGCCATGACGGACGTG GCCTCCTTAAAAAAGATCCGCAACCTCAACACTGATTATCTAGTGATAAGGTGAAGTCTCGCCCCCTCCCTCCGT TGGGGATTCTACTTCTGACTGGCACTCTCAGGTCGCTCAACAACTATCGCAAAGCCGACGTGGAACGCGAGCAGG CTCTCAAGTTCGTGCGGGCCTTCCTTGACGTCAAGGACGGCGTCAGGGAAATCTCTCGGGCCGTAGTGCGCACCA TTGTCGCGGTCGCCGAGCAGGGTGAGGAACGTCGCCCCGGCGGCGCTAATGTCGCCGACCACAATATTGATCGGC TGCGCCCAATATGCATCGAGACGCTCGCAGAAATACTGGTGGGCGATCCGCAGCTCCTCATTGCATCGGGCGGCC TTGGGCCCCTCTCGGAAGCTTTGGGCGAGGGCACATACAAGGCCCCGGAGAGCTTGATGTCTGCTTTCCTCTTCC TCCTCGACACGCCCGGCAAACGCAAATACATTCAGCCCGGCTACGGCTTGGACGTCGTGTTTACCGCCTTCACCG ACCAGCTCGCCGGGGCGGAGAGCATTCTCAAACAGAACTCCAGAGCCATATCCGTTGCCATGAAGTCGTGGTCCG GCCTGATGACCCTTGGCATGTACGATTTTCGGCCGATCCGTTCGCTCATCGCGAGCATATTGTTTCCCAACTCAG CAATACGCGAGACTGTTCTGGACCTGCTGTTCTCCCTGCTGCGGATCAAGCCACCTGCCTGGGCCACATCATTCT TAGCCGGACGCCGGTTGACGACATACGGGAGAGTGGCCAATATGAAGTCGACCAACGGCAGGGAAAGGAGCGCCA CGCTCTCCCTGGAAGAGGACAGCGGCGAGCAGAACTTTGTCGATCACTACACGGCGCTGCTGCTGGCCGTCTTCA TTCAGGCGGGGCTGCTGCAAAGACTGCTGCAGATAGCGCAGTCAGAAGAAGACTCGATGCTGAAGCGCAAAACGA CACTGCTGATCGGCGAGGTGCTGAAGCTGGCCAGCCGATTACTCCCTCCCGCATGGAGCGCCGAGCTGCAGCTTC TGCCGGAGCTGTTCTCGGCGGCCGCACAGTTCGGCAACGAGGCTCACTTTGTGGCGTCGGGCATCGTCTACCAGA TCAGCAGCGTCAGTAGGACGCTGTACAGGAGCGCCCCGTCCGAGTCCATGGCCGGCGCCCTGCCATCCAGCGACA GCATGCAACACCTGGCAATGTTCGAGGAACACCCCAAGGCCAACGCGGCCATGGTCTTCGACGATGCAACGTTCC GCCAGCTCCTCATCGACACGGGCGTCCTCAACAGTTCCAACTACTTGAAGTGGAACTGGGAGGTCATCATCAAGG TCATAGACGGGCCCTTGCAGATCGGGAAGCGGCTGGAAGAGGCCATCAGGGCTTCGAAGTTCATGAAGCGCATCA TGAGCTTCTACAGGCCCTTCAAGTACAAGTTCGCCGAGATCAAGAACACGAGGAACACGCAGAAGTACGTCAGAG CCGGCTGTGCGCTGGTGCATTCTCTGCTCCAGTCGACCGAGGGTGTAAGGGTCTTGGCGGACAGCAAGCTGCTGA GACAGATCGCCGAGTGTCTTGCCCAGTGCGATCCGGCAAGTTCCACAACACGGGCTAGACGGACATGTCGCACGG GGGCGTCGGCTAACAACACTCGCAGACCAGCGGCCTCACCGCGCAGTTTCCCATGTTTGCAAAGGACCGACTCAC GGACACGCTCTGTGGAGGCTACTTCCCCATGCTTGGCGTCCTCAGCAGCTACTCCCAGGGGTTGCTTCTACTGGA GAGGTGGAGGATGTTCAACATGATGTACCATATCGTCGACCTGAAGCAGCGGCCCGATCTCATCAAGCTCCTCCT GTCTAACTTTGACTACAGCCTTCAGGGCCACCCCCGAGTCCTACTTTCCAAGGCCCTGATCGCGGGCAACAAGAA CATTCGAATACACGCGACGAACACACTGCGCAAGTGTACAATGAGGCCGGTAACCTCGCTCAGCGGCCAGGGCAA CGCTAGCGACGCGAAGTGGGCCATTCAGCTCCTCGTCACGCAGCTATACGATCCAGAAATCGAGGTCTGCTCCAC GGCCGTCAAGATTCTCGAGAACGCGTGCAACCGAAAGGTCTTCCTGGAATACATCGTCGAGTGTCGGCCCGCCCT CGACCACCTGGGCGAGATCGGGGCACCCCTGCTGCTGCGGTTCTTGTCCACCTCGATCGGTTATCACTACCTGGA CGGGCTGGACTACATCAGCAATGAGATGGACGACTGGTTTCTGGGCCGGAACGACTCGTACGTCGACGTCATCGA GGCCAGTCTGGCGAGAGCCTTCCTGGCCGGCCCCGACGATCACGGCCACCGCGTCAGCCTATTCAACGAGGCGGA GGCGGAGACGGACTTTCACGACAGCCACGTGCCGCCGCACTTCTACCGAGAGCTCACCCGCACGCGCGAGGGCTG CAAGCTCTTGAGCGATAAGGGCCACTTCGAGGAGTTCGTGGCGACGATCCGCGATCACGGCATGCAGACCGAGGA CGGCGAGCTGATGACCAAGGTCAAGGGCTGTCTTTGGGCAGTGGGCAACGTGGGGTCGATGGAGCTCGGGGCGCC GTTCCTGGAAGCGAGCGACGTGGTCGAGCGTATCATCGACATCGCCGAGTCGCACGAAGTCATGAGTCTGCGCGG CACGGCCTTCTTCGTGCTGGGGCTCATCTCGCGCTCCACCCACGGCCTGGAGATCCTGTCGGAACACGGATGGGA CGCGAACACGACATCGATGGGGGCGTCACTCGGCTTTTGCATCCCCAACGACCTGTCGAGGCTTTTTTCGATGAG GCCTTGGCAGCACGTCAAGGCCGCGTCCATCAAGCTGCTCGACACGCAACGGACCGCGCGGGAGCAGCCGTCGGT CCGACAGGCGCGCCCGCCACTGGAGCCGTCAGAGATGCCGCCGCTCGTCAGTGAGGCGGACATCAATGAACGCAT TATGGAGTTGGTGGTGGACTTGGGTAACATGGTGCTGTACAAGAAGGCGGTGGGCGAGCTGCAGAAGCTCAAGAC GCGCAAGCCGAACGCGTTCCGCAGCACTGATTTCTTCAAGAAGGTGATGGGTCTGATGGAGTGGAACCACTACCG GCTCGGGGTACGGAGGCTCGTGATTGACCTGTTCGAGAAGCACGTGATGCGACAGATCGTGTTTGGCGAGGACGA AGGCAGCGGCGGCGGCAACGGAGATGTTGGGCCAGCGGGAGACGACAGCGGCGACGGCAGCTCCGGGGACGACCG GACAGAGAGGCAGAGGAGCATCAGTGAGCCGGCGGAGATGCCGTCGGATCTAATGCCGGCGCCGCTCAAAGTACG GCGCTGA |