© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|6862 |
| Gene name | |
| Location | Contig_37:42561..43726 |
| Strand | - |
| Gene length (bp) | 1165 |
| Transcript length (bp) | 1044 |
| Coding sequence length (bp) | 1044 |
| Protein length (aa) | 348 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF04116 | FA_hydroxylase | Fatty acid hydroxylase | 6.0E-25 | 169 | 295 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q7SBB6|ERG3_NEUCR | Probable Delta(7)-sterol 5(6)-desaturase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=NCU06207 PE=3 SV=1 | 1 | 345 | 6.0E-174 |
| sp|Q8J207|ERG3_LEPMC | Delta(7)-sterol 5(6)-desaturase OS=Leptosphaeria maculans GN=ERG3 PE=3 SV=1 | 1 | 347 | 6.0E-155 |
| sp|Q754B9|ERG3_ASHGO | Delta(7)-sterol 5(6)-desaturase OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=ERG3 PE=3 SV=2 | 1 | 337 | 2.0E-107 |
| sp|P50860|ERG3_CANGA | Delta(7)-sterol 5(6)-desaturase OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=ERG3 PE=3 SV=1 | 1 | 347 | 6.0E-107 |
| sp|O93875|ERG3_CANAX | Delta(7)-sterol 5(6)-desaturase OS=Candida albicans GN=ERG3 PE=3 SV=1 | 1 | 337 | 3.0E-105 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q7SBB6|ERG3_NEUCR | Probable Delta(7)-sterol 5(6)-desaturase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=NCU06207 PE=3 SV=1 | 1 | 345 | 6.0E-174 |
| sp|Q8J207|ERG3_LEPMC | Delta(7)-sterol 5(6)-desaturase OS=Leptosphaeria maculans GN=ERG3 PE=3 SV=1 | 1 | 347 | 6.0E-155 |
| sp|Q754B9|ERG3_ASHGO | Delta(7)-sterol 5(6)-desaturase OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=ERG3 PE=3 SV=2 | 1 | 337 | 2.0E-107 |
| sp|P50860|ERG3_CANGA | Delta(7)-sterol 5(6)-desaturase OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=ERG3 PE=3 SV=1 | 1 | 347 | 6.0E-107 |
| sp|O93875|ERG3_CANAX | Delta(7)-sterol 5(6)-desaturase OS=Candida albicans GN=ERG3 PE=3 SV=1 | 1 | 337 | 3.0E-105 |
| sp|P32353|ERG3_YEAST | Delta(7)-sterol 5(6)-desaturase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG3 PE=1 SV=1 | 1 | 347 | 4.0E-105 |
| sp|O94457|ERG31_SCHPO | Delta(7)-sterol 5(6)-desaturase erg31 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg31 PE=3 SV=1 | 68 | 345 | 2.0E-101 |
| sp|Q8NJ57|ERG3_CANDC | Delta(7)-sterol 5(6)-desaturase OS=Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) GN=ERG3 PE=3 SV=1 | 1 | 337 | 1.0E-100 |
| sp|O13666|ERG32_SCHPO | Delta(7)-sterol 5(6)-desaturase erg32 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg32 PE=3 SV=1 | 1 | 347 | 5.0E-94 |
| sp|O75845|SC5D_HUMAN | Lathosterol oxidase OS=Homo sapiens GN=SC5D PE=1 SV=2 | 63 | 321 | 2.0E-83 |
| sp|O88822|SC5D_MOUSE | Lathosterol oxidase OS=Mus musculus GN=Sc5d PE=2 SV=2 | 63 | 324 | 2.0E-82 |
| sp|Q9EQS5|SC5D_RAT | Lathosterol oxidase OS=Rattus norvegicus GN=Sc5d PE=1 SV=1 | 63 | 324 | 3.0E-82 |
| sp|Q9M883|SC5D2_ARATH | Putative Delta(7)-sterol-C5(6)-desaturase 2 OS=Arabidopsis thaliana GN=HDF7 PE=3 SV=1 | 88 | 301 | 4.0E-21 |
| sp|Q39208|SC5D1_ARATH | Delta(7)-sterol-C5(6)-desaturase 1 OS=Arabidopsis thaliana GN=STE1 PE=1 SV=2 | 121 | 314 | 4.0E-20 |
| sp|Q9ZT29|SC5D_TOBAC | Delta(7)-sterol-C5(6)-desaturase OS=Nicotiana tabacum PE=2 SV=1 | 84 | 310 | 9.0E-20 |
| sp|Q9AST3|SBH2_ARATH | Sphinganine C4-monooxygenase 2 OS=Arabidopsis thaliana GN=SBH2 PE=1 SV=1 | 82 | 314 | 2.0E-11 |
| sp|Q55D54|MSMOB_DICDI | Putative methylsterol monooxygenase DDB_G0269788 OS=Dictyostelium discoideum GN=DDB_G0269788 PE=3 SV=1 | 159 | 314 | 3.0E-10 |
| sp|Q55D52|MSMOA_DICDI | Putative methylsterol monooxygenase DDB_G0270946 OS=Dictyostelium discoideum GN=DDB_G0270946 PE=3 SV=2 | 116 | 314 | 4.0E-10 |
| sp|Q9GKT2|FXDC2_MACFA | Fatty acid hydroxylase domain-containing protein 2 OS=Macaca fascicularis GN=FAXDC2 PE=2 SV=1 | 124 | 295 | 2.0E-09 |
| sp|Q96IV6|FXDC2_HUMAN | Fatty acid hydroxylase domain-containing protein 2 OS=Homo sapiens GN=FAXDC2 PE=2 SV=1 | 157 | 295 | 3.0E-09 |
| sp|Q9CRA4|MSMO1_MOUSE | Methylsterol monooxygenase 1 OS=Mus musculus GN=Msmo1 PE=1 SV=1 | 180 | 314 | 7.0E-09 |
| sp|Q5R574|MSMO1_PONAB | Methylsterol monooxygenase 1 OS=Pongo abelii GN=MSMO1 PE=2 SV=1 | 132 | 313 | 1.0E-08 |
| sp|Q15800|MSMO1_HUMAN | Methylsterol monooxygenase 1 OS=Homo sapiens GN=MSMO1 PE=1 SV=1 | 132 | 313 | 1.0E-08 |
| sp|Q5ZLL6|MSMO1_CHICK | Methylsterol monooxygenase 1 OS=Gallus gallus GN=MSMO1 PE=2 SV=1 | 180 | 313 | 2.0E-08 |
| sp|Q8L7W5|SMO11_ARATH | Methylsterol monooxygenase 1-1 OS=Arabidopsis thaliana GN=SMO1-1 PE=1 SV=1 | 167 | 314 | 2.0E-08 |
| sp|P53045|MSMO_YEAST | Methylsterol monooxygenase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG25 PE=1 SV=1 | 159 | 313 | 2.0E-08 |
| sp|F4JLZ6|SMO13_ARATH | Methylsterol monooxygenase 1-3 OS=Arabidopsis thaliana GN=SMO1-3 PE=2 SV=1 | 159 | 295 | 2.0E-08 |
| sp|O35532|MSMO1_RAT | Methylsterol monooxygenase 1 OS=Rattus norvegicus GN=Msmo1 PE=2 SV=1 | 180 | 314 | 3.0E-08 |
| sp|Q6UGB2|MSMO1_PIG | Methylsterol monooxygenase 1 OS=Sus scrofa GN=MSMO1 PE=2 SV=1 | 136 | 313 | 4.0E-08 |
| sp|Q7ZW77|MSMO1_DANRE | Methylsterol monooxygenase 1 OS=Danio rerio GN=msmo1 PE=2 SV=1 | 180 | 295 | 9.0E-08 |
| sp|Q8VYI1|SBH1_ARATH | Sphinganine C4-monooxygenase 1 OS=Arabidopsis thaliana GN=SBH1 PE=1 SV=1 | 167 | 296 | 1.0E-07 |
| sp|Q1EC69|SMO12_ARATH | Methylsterol monooxygenase 1-2 OS=Arabidopsis thaliana GN=SMO1-2 PE=2 SV=1 | 165 | 314 | 2.0E-07 |
| sp|Q4R4Q4|MSMO1_MACFA | Methylsterol monooxygenase 1 OS=Macaca fascicularis GN=MSMO1 PE=2 SV=1 | 136 | 295 | 2.0E-06 |
| sp|P38992|SUR2_YEAST | Sphingolipid C4-hydroxylase SUR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SUR2 PE=1 SV=1 | 160 | 330 | 4.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0016491 | oxidoreductase activity | Yes |
| GO:0005506 | iron ion binding | Yes |
| GO:0008610 | lipid biosynthetic process | Yes |
| GO:0008152 | metabolic process | No |
| GO:0003824 | catalytic activity | No |
| GO:0046872 | metal ion binding | No |
| GO:0005488 | binding | No |
| GO:0043167 | ion binding | No |
| GO:0071704 | organic substance metabolic process | No |
| GO:0044238 | primary metabolic process | No |
| GO:0006629 | lipid metabolic process | No |
| GO:0009058 | biosynthetic process | No |
| GO:0046914 | transition metal ion binding | No |
| GO:1901576 | organic substance biosynthetic process | No |
| GO:0003674 | molecular_function | No |
| GO:0008150 | biological_process | No |
| GO:0043169 | cation binding | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 19 | 0.45 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 82 | 104 | 22 |
| 2 | 130 | 149 | 19 |
| 3 | 161 | 183 | 22 |
| 4 | 231 | 253 | 22 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|6862 MDIVLELTDTFIADYVYAYLFPARPAPYDFPQATAANVSQQTFSAWTYRPATKFLQVQPSQAAYTTSLPRDHPYR QLATLYFITWIFGIIVYFLFATLSYFLIFDKRTLDHPKFIKNQIWLEIKQANKSMPLMAIFTVPFFLLEVRGYGK LYDTTDEGPGLWYNILQFPLFLLFTDFCIYWIHRYLHHPLIYKRLHKPHHKWIMPTPYASHAFHPMDGFAQSLPY HIFPFIFPLQKMAFVCLFVFVNFWSILIHDGEYLTNNPVVNGAACHSLHHSRFEVNYGQFFTAFDRLGGTYRRPE AWMFEREKKMSKKQWTKESRAVDEFVKEIEGTDERTYGPDSAAKKIN* |
| Coding | >Hirsu2|6862 ATGGATATCGTCCTCGAGCTCACCGACACCTTCATCGCCGACTACGTCTACGCCTACCTTTTCCCCGCCCGCCCC GCGCCCTACGACTTCCCCCAAGCCACCGCGGCCAACGTCTCCCAGCAGACTTTTTCCGCCTGGACATACCGGCCC GCGACCAAGTTCCTCCAGGTCCAGCCCTCCCAGGCCGCCTACACGACGTCGCTGCCGCGCGACCATCCCTATCGC CAGCTCGCCACGCTATACTTTATTACCTGGATCTTCGGCATCATCGTCTATTTCCTCTTCGCCACCCTCTCCTAC TTCCTCATCTTCGACAAGCGCACCCTGGATCATCCCAAGTTCATCAAGAATCAGATATGGCTCGAGATCAAGCAG GCAAACAAGTCGATGCCCCTTATGGCCATCTTCACCGTCCCCTTCTTCCTCCTTGAGGTCCGCGGCTACGGAAAG CTCTACGATACGACCGACGAAGGGCCGGGTCTGTGGTACAACATCCTGCAGTTCCCCCTCTTCCTCCTCTTCACG GACTTTTGCATTTACTGGATCCACCGATACCTACACCATCCCCTCATCTACAAGCGTCTTCACAAGCCTCACCAC AAGTGGATCATGCCCACGCCTTACGCCAGCCACGCCTTCCACCCGATGGACGGTTTCGCCCAGTCGCTTCCTTAC CACATCTTCCCCTTCATCTTCCCACTGCAGAAGATGGCTTTCGTCTGCCTCTTCGTCTTCGTCAACTTCTGGTCC ATCCTCATCCACGACGGAGAATATCTCACCAACAACCCTGTCGTCAACGGCGCCGCCTGCCACTCCCTACACCAC TCTCGCTTCGAGGTCAACTACGGCCAGTTCTTCACGGCCTTTGACCGTCTCGGCGGCACCTACAGGCGGCCCGAG GCCTGGATGTTTGAGCGGGAGAAGAAGATGTCGAAAAAGCAGTGGACCAAGGAATCGCGAGCCGTCGACGAGTTT GTCAAGGAGATCGAGGGTACCGACGAACGCACCTATGGCCCCGACTCGGCTGCCAAGAAAATCAACTGA |
| Transcript | >Hirsu2|6862 ATGGATATCGTCCTCGAGCTCACCGACACCTTCATCGCCGACTACGTCTACGCCTACCTTTTCCCCGCCCGCCCC GCGCCCTACGACTTCCCCCAAGCCACCGCGGCCAACGTCTCCCAGCAGACTTTTTCCGCCTGGACATACCGGCCC GCGACCAAGTTCCTCCAGGTCCAGCCCTCCCAGGCCGCCTACACGACGTCGCTGCCGCGCGACCATCCCTATCGC CAGCTCGCCACGCTATACTTTATTACCTGGATCTTCGGCATCATCGTCTATTTCCTCTTCGCCACCCTCTCCTAC TTCCTCATCTTCGACAAGCGCACCCTGGATCATCCCAAGTTCATCAAGAATCAGATATGGCTCGAGATCAAGCAG GCAAACAAGTCGATGCCCCTTATGGCCATCTTCACCGTCCCCTTCTTCCTCCTTGAGGTCCGCGGCTACGGAAAG CTCTACGATACGACCGACGAAGGGCCGGGTCTGTGGTACAACATCCTGCAGTTCCCCCTCTTCCTCCTCTTCACG GACTTTTGCATTTACTGGATCCACCGATACCTACACCATCCCCTCATCTACAAGCGTCTTCACAAGCCTCACCAC AAGTGGATCATGCCCACGCCTTACGCCAGCCACGCCTTCCACCCGATGGACGGTTTCGCCCAGTCGCTTCCTTAC CACATCTTCCCCTTCATCTTCCCACTGCAGAAGATGGCTTTCGTCTGCCTCTTCGTCTTCGTCAACTTCTGGTCC ATCCTCATCCACGACGGAGAATATCTCACCAACAACCCTGTCGTCAACGGCGCCGCCTGCCACTCCCTACACCAC TCTCGCTTCGAGGTCAACTACGGCCAGTTCTTCACGGCCTTTGACCGTCTCGGCGGCACCTACAGGCGGCCCGAG GCCTGGATGTTTGAGCGGGAGAAGAAGATGTCGAAAAAGCAGTGGACCAAGGAATCGCGAGCCGTCGACGAGTTT GTCAAGGAGATCGAGGGTACCGACGAACGCACCTATGGCCCCGACTCGGCTGCCAAGAAAATCAACTGA |
| Gene | >Hirsu2|6862 ATGGATATCGTCCTCGAGCTCACCGACACCTTCATCGCCGACTACGTCTACGCCTACCTTTTCCCCGCCCGCCCC GCGCCCTACGACTTCCCCCAAGCCACCGCGGCCAACGTCTCCCAGCAGACTTTTTCCGCCTGGACATACCGGCCC GCGACCAAGTTCCTCCAGGTCCAGCCCTCCCAGGCCGCCTACACGACGTCGCTGCCGCGCGACCATCCCTATCGC CAGCTCGCCACGCTATACTTTATTACCTGGTGCGCTGCCTCTCCCCNNNNNNNNNNNNNNNNNNNNNNNNNNCCC CCCCCTTTTTTTTTTGTCGCTCCCGGCTGCTCTTGTCTGAGGTGCCCCCGTAACCCTAACCGGCTTCGTTTGCAG GATCTTCGGCATCATCGTCTATTTCCTCTTCGCCACCCTCTCCTACTTCCTCATCTTCGACAAGCGCACCCTGGA TCATCCCAAGTTCATCAAGAATCAGATATGGCTCGAGATCAAGCAGGCAAACAAGTCGATGCCCCTTATGGCCAT CTTCACCGTCCCCTTCTTCCTCCTTGAGGTCCGCGGCTACGGAAAGCTCTACGATACGACCGACGAAGGGCCGGG TCTGTGGTACAACATCCTGCAGTTCCCCCTCTTCCTCCTCTTCACGGACTTTTGCATTTACTGGATCCACCGATA CCTACACCATCCCCTCATCTACAAGCGTCTTCACAAGCCTCACCACAAGTGGATCATGCCCACGCCTTACGCCAG CCACGCCTTCCACCCGATGGACGGTTTCGCCCAGTCGCTTCCTTACCACATCTTCCCCTTCATCTTCCCACTGCA GAAGATGGCTTTCGTCTGCCTCTTCGTCTTCGTCAACTTCTGGTCCATCCTCATCCACGACGGAGAATATCTCAC CAACAACCCTGTCGTCAACGGCGCCGCCTGCCACTCCCTACACCACTCTCGCTTCGAGGTCAACTACGGCCAGTT CTTCACGGCCTTTGACCGTCTCGGCGGCACCTACAGGCGGCCCGAGGCCTGGATGTTTGAGCGGGAGAAGAAGAT GTCGAAAAAGCAGTGGACCAAGGAATCGCGAGCCGTCGACGAGTTTGTCAAGGAGATCGAGGGTACCGACGAACG CACCTATGGCCCCGACTCGGCTGCCAAGAAAATCAACTGA |