© 2023 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|6409 |
| Gene name | |
| Location | Contig_329:13844..16082 |
| Strand | + |
| Gene length (bp) | 2238 |
| Transcript length (bp) | 2238 |
| Coding sequence length (bp) | 2238 |
| Protein length (aa) | 746 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF02145 | Rap_GAP | Rap/ran-GAP | 5.2E-55 | 440 | 644 |
| PF03542 | Tuberin | Tuberin | 2.0E-31 | 9 | 192 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q9UUG9|TSC2_SCHPO | Tuberous sclerosis 2 protein homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tsc2 PE=1 SV=1 | 15 | 648 | 2.0E-132 |
| sp|P49815|TSC2_HUMAN | Tuberin OS=Homo sapiens GN=TSC2 PE=1 SV=2 | 394 | 661 | 3.0E-42 |
| sp|P49816|TSC2_RAT | Tuberin OS=Rattus norvegicus GN=Tsc2 PE=1 SV=1 | 375 | 648 | 1.0E-40 |
| sp|Q61037|TSC2_MOUSE | Tuberin OS=Mus musculus GN=Tsc2 PE=1 SV=1 | 394 | 648 | 3.0E-37 |
| sp|Q6GYP7|RGPA1_MOUSE | Ral GTPase-activating protein subunit alpha-1 OS=Mus musculus GN=Ralgapa1 PE=1 SV=1 | 401 | 617 | 1.0E-21 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q9UUG9|TSC2_SCHPO | Tuberous sclerosis 2 protein homolog OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tsc2 PE=1 SV=1 | 15 | 648 | 2.0E-132 |
| sp|P49815|TSC2_HUMAN | Tuberin OS=Homo sapiens GN=TSC2 PE=1 SV=2 | 394 | 661 | 3.0E-42 |
| sp|P49816|TSC2_RAT | Tuberin OS=Rattus norvegicus GN=Tsc2 PE=1 SV=1 | 375 | 648 | 1.0E-40 |
| sp|Q61037|TSC2_MOUSE | Tuberin OS=Mus musculus GN=Tsc2 PE=1 SV=1 | 394 | 648 | 3.0E-37 |
| sp|Q6GYP7|RGPA1_MOUSE | Ral GTPase-activating protein subunit alpha-1 OS=Mus musculus GN=Ralgapa1 PE=1 SV=1 | 401 | 617 | 1.0E-21 |
| sp|O55007|RGPA1_RAT | Ral GTPase-activating protein subunit alpha-1 OS=Rattus norvegicus GN=Ralgapa1 PE=1 SV=2 | 401 | 617 | 1.0E-21 |
| sp|Q6GYQ0|RGPA1_HUMAN | Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens GN=RALGAPA1 PE=1 SV=1 | 401 | 617 | 2.0E-21 |
| sp|A3KGS3|RGPA2_MOUSE | Ral GTPase-activating protein subunit alpha-2 OS=Mus musculus GN=Ralgapa2 PE=1 SV=2 | 409 | 617 | 7.0E-20 |
| sp|P86411|RGPA2_RAT | Ral GTPase-activating protein subunit alpha-2 OS=Rattus norvegicus GN=Ralgapa2 PE=1 SV=1 | 409 | 617 | 7.0E-20 |
| sp|P49815|TSC2_HUMAN | Tuberin OS=Homo sapiens GN=TSC2 PE=1 SV=2 | 13 | 265 | 1.0E-19 |
| sp|Q61037|TSC2_MOUSE | Tuberin OS=Mus musculus GN=Tsc2 PE=1 SV=1 | 13 | 266 | 4.0E-19 |
| sp|Q2PPJ7|RGPA2_HUMAN | Ral GTPase-activating protein subunit alpha-2 OS=Homo sapiens GN=RALGAPA2 PE=1 SV=2 | 409 | 617 | 5.0E-19 |
| sp|P49816|TSC2_RAT | Tuberin OS=Rattus norvegicus GN=Tsc2 PE=1 SV=1 | 13 | 265 | 7.0E-19 |
| sp|Q9VB98|Y5521_DROME | Probable Rho GTPase-activating protein CG5521 OS=Drosophila melanogaster GN=CG5521 PE=1 SV=2 | 409 | 617 | 2.0E-17 |
| sp|Q9P2F8|SI1L2_HUMAN | Signal-induced proliferation-associated 1-like protein 2 OS=Homo sapiens GN=SIPA1L2 PE=1 SV=2 | 423 | 551 | 2.0E-15 |
| sp|Q55AN8|Y1806_DICDI | PH and Rap-GAP domain-containing protein DDB_G0271806 OS=Dictyostelium discoideum GN=DDB_G0271806 PE=3 SV=1 | 409 | 621 | 2.0E-15 |
| sp|Q5JCS6|SI1L2_RAT | Signal-induced proliferation-associated 1-like protein 2 OS=Rattus norvegicus GN=Sipa1l2 PE=1 SV=1 | 423 | 551 | 3.0E-15 |
| sp|O60292|SI1L3_HUMAN | Signal-induced proliferation-associated 1-like protein 3 OS=Homo sapiens GN=SIPA1L3 PE=1 SV=3 | 423 | 551 | 3.0E-15 |
| sp|P47736|RPGP1_HUMAN | Rap1 GTPase-activating protein 1 OS=Homo sapiens GN=RAP1GAP PE=1 SV=2 | 407 | 593 | 4.0E-15 |
| sp|Q80TE4|SI1L2_MOUSE | Signal-induced proliferation-associated 1-like protein 2 OS=Mus musculus GN=Sipa1l2 PE=1 SV=3 | 423 | 551 | 4.0E-15 |
| sp|A2ALS5|RPGP1_MOUSE | Rap1 GTPase-activating protein 1 OS=Mus musculus GN=Rap1gap PE=1 SV=2 | 407 | 593 | 5.0E-15 |
| sp|Q8C0T5|SI1L1_MOUSE | Signal-induced proliferation-associated 1-like protein 1 OS=Mus musculus GN=Sipa1l1 PE=1 SV=2 | 423 | 551 | 3.0E-14 |
| sp|O43166|SI1L1_HUMAN | Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens GN=SIPA1L1 PE=1 SV=4 | 423 | 551 | 4.0E-14 |
| sp|O35412|SI1L1_RAT | Signal-induced proliferation-associated 1-like protein 1 OS=Rattus norvegicus GN=Sipa1l1 PE=1 SV=1 | 423 | 551 | 4.0E-14 |
| sp|Q96FS4|SIPA1_HUMAN | Signal-induced proliferation-associated protein 1 OS=Homo sapiens GN=SIPA1 PE=1 SV=1 | 424 | 551 | 7.0E-14 |
| sp|P46062|SIPA1_MOUSE | Signal-induced proliferation-associated protein 1 OS=Mus musculus GN=Sipa1 PE=1 SV=2 | 424 | 551 | 6.0E-13 |
| sp|Q5ZMV8|RPGP2_CHICK | Rap1 GTPase-activating protein 2 OS=Gallus gallus GN=RAP1GAP2 PE=2 SV=2 | 407 | 551 | 6.0E-13 |
| sp|Q5ZJY3|GARL3_CHICK | GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Gallus gallus GN=GARNL3 PE=2 SV=1 | 424 | 530 | 1.0E-12 |
| sp|Q5VVW2|GARL3_HUMAN | GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Homo sapiens GN=GARNL3 PE=2 SV=2 | 424 | 530 | 4.0E-12 |
| sp|Q684P5|RPGP2_HUMAN | Rap1 GTPase-activating protein 2 OS=Homo sapiens GN=RAP1GAP2 PE=1 SV=2 | 407 | 593 | 6.0E-12 |
| sp|Q5SVL6|RPGP2_MOUSE | Rap1 GTPase-activating protein 2 OS=Mus musculus GN=Rap1gap2 PE=1 SV=1 | 407 | 593 | 1.0E-11 |
| sp|Q3V0G7|GARL3_MOUSE | GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Mus musculus GN=Garnl3 PE=1 SV=1 | 424 | 530 | 9.0E-11 |
| sp|A5PF44|GARL3_DANRE | GTPase-activating Rap/Ran-GAP domain-like protein 3 OS=Danio rerio GN=garnl3 PE=3 SV=1 | 424 | 547 | 1.0E-10 |
| sp|Q54TK4|Y1809_DICDI | Rap-GAP domain-containing protein DDB_G0281809 OS=Dictyostelium discoideum GN=DDB_G0281809 PE=3 SV=1 | 409 | 617 | 2.0E-09 |
| sp|Q75J96|RGAP1_DICDI | RapA guanosine triphosphatase-activating protein 1 OS=Dictyostelium discoideum GN=rapgap1 PE=2 SV=1 | 424 | 551 | 3.0E-09 |
| sp|Q54EH3|Y1510_DICDI | GTPase-activating protein DDB_G0291510 OS=Dictyostelium discoideum GN=DDB_G0291510 PE=3 SV=1 | 422 | 559 | 3.0E-09 |
| sp|Q54SS8|RGAPB_DICDI | RapA guanosine triphosphatase-activating protein B OS=Dictyostelium discoideum GN=rapgapB PE=2 SV=1 | 424 | 553 | 2.0E-08 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0051056 | regulation of small GTPase mediated signal transduction | Yes |
| GO:0005096 | GTPase activator activity | Yes |
| GO:0043547 | positive regulation of GTPase activity | Yes |
| GO:0009966 | regulation of signal transduction | No |
| GO:0043085 | positive regulation of catalytic activity | No |
| GO:0008150 | biological_process | No |
| GO:0098772 | molecular function regulator activity | No |
| GO:0010646 | regulation of cell communication | No |
| GO:0065009 | regulation of molecular function | No |
| GO:0051345 | positive regulation of hydrolase activity | No |
| GO:0050794 | regulation of cellular process | No |
| GO:0048583 | regulation of response to stimulus | No |
| GO:0030695 | GTPase regulator activity | No |
| GO:0060589 | nucleoside-triphosphatase regulator activity | No |
| GO:0023051 | regulation of signaling | No |
| GO:0043087 | regulation of GTPase activity | No |
| GO:0065007 | biological regulation | No |
| GO:0008047 | enzyme activator activity | No |
| GO:0044093 | positive regulation of molecular function | No |
| GO:0051336 | regulation of hydrolase activity | No |
| GO:0003674 | molecular_function | No |
| GO:1902531 | regulation of intracellular signal transduction | No |
| GO:0030234 | enzyme regulator activity | No |
| GO:0050790 | regulation of catalytic activity | No |
| GO:0050789 | regulation of biological process | No |
| Localizations | Signals | Cytoplasm | Nucleus | Extracellular | Cell membrane | Mitochondrion | Plastid | Endoplasmic reticulum | Lysosome vacuole | Golgi apparatus | Peroxisome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytoplasm | Nuclear export signal | 0.6174 | 0.4136 | 0.0542 | 0.1884 | 0.115 | 0.0046 | 0.3059 | 0.4267 | 0.4064 | 0.0151 |
| Orthofinder run ID | 4 |
| Orthogroup | 3412 |
| Change Orthofinder run |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|6409 MSVWLDAVLAILQGSDWEVCSFVLVHLPSQLSNHAIFRDAIPQIQELRRIICEQIRTNGFQEPPNASGLRRADVA ICLFHSLTMILSYHEHFQKSDEDDIVKTFALGIAAWERTAKYCIHALSICCHELPLSTSKSLIQLLNQMAAIITQ PHVSVHILEFLASLSRLHNVFVNFREDDYRIVFGICFRYLEYAKEKKQSNRSSHVSEVSTPGSNHAEPPSTSPAD ELPQYVHALAYHVILFWFLALKLQDRAHHVGWIVKKLFSDADGHGPAADDQTLTTIDFMQRVTFADVGESAEDPY FSEDRFGAIVKKQWLLGNSIVTIKQATGSGWAQVIKRQPSGTSAYMVRESFTPTPPHQTAAYVDVSREGQATSDA ILPSHLLVQLMSPVPQILEEARPIPLPDDEIADRAIRVFDRNSSLDGHKVGVIYIGEGQTQEAEILANVSGSRDY LEFLNNLGTLTKLKGSTFNTQGLDREYDSDGQYTFCWRDRVTEIVFHVTTQMPTDLERDPNCTLKKRHIGNDFVN IIFNDSALPFQFETFPSQFNFVNIVITPASRASFVAMRTRGADRGQSQKQPFYRVQVMSKPGFPEVSPASETKMI SLKALPGFIRLLALNASMFSVVWHNREGGEHISSWSARLREIKRLREKHGPKAATTASSPPASSWHGGASHAQQA DTSRAGSSVRDSFSSLRRTSVATFFTSTSEQMSHRSSTLSTSATSHDTELPPTAAAANTLVDSVDFSKWA* |
| Coding | >Hirsu2|6409 ATGTCGGTCTGGCTCGATGCTGTCTTGGCAATCCTTCAAGGCAGTGACTGGGAGGTGTGCAGCTTCGTACTTGTC CATCTCCCGTCGCAGCTCAGCAATCATGCCATCTTCAGAGATGCGATCCCGCAGATTCAGGAACTTCGCAGGATC ATCTGTGAGCAGATCCGGACAAACGGCTTCCAAGAGCCGCCCAACGCTTCAGGGCTGCGACGAGCGGACGTGGCC ATCTGTCTCTTCCACAGCTTGACTATGATTCTTAGCTATCACGAGCACTTTCAGAAAAGCGATGAGGATGACATT GTAAAGACTTTCGCTCTCGGCATCGCCGCGTGGGAACGAACGGCGAAATACTGCATCCATGCGCTCTCTATTTGC TGCCACGAGCTCCCGCTCTCGACGAGCAAGTCGCTGATCCAGTTGCTGAATCAGATGGCTGCGATCATCACGCAG CCTCACGTTTCCGTCCACATCCTGGAGTTTCTCGCCTCCTTGAGCCGGCTTCACAACGTCTTTGTCAATTTCCGA GAGGACGACTACCGGATCGTCTTTGGCATTTGCTTCCGCTACTTGGAGTACGCCAAAGAGAAGAAGCAGTCCAAC CGCAGCAGCCACGTCAGCGAAGTGTCGACTCCGGGCTCGAACCACGCGGAACCCCCCAGCACGAGCCCTGCCGAT GAGCTTCCGCAATACGTCCATGCATTGGCCTATCACGTCATATTGTTCTGGTTCCTTGCTTTGAAGCTGCAGGAT CGGGCACACCACGTAGGGTGGATTGTCAAGAAACTCTTTTCGGATGCAGACGGGCACGGACCGGCGGCTGACGAC CAGACGCTCACAACGATCGACTTTATGCAAAGGGTCACTTTCGCAGACGTGGGCGAGTCTGCTGAAGACCCCTAC TTCAGCGAGGATCGCTTCGGCGCCATCGTCAAGAAACAGTGGCTGCTGGGCAACAGCATCGTAACGATCAAGCAG GCCACAGGGTCCGGGTGGGCTCAAGTTATCAAGAGACAGCCGTCGGGAACGTCGGCGTACATGGTTCGCGAGTCA TTCACGCCGACTCCGCCGCATCAGACAGCGGCCTACGTCGACGTGAGCCGGGAGGGCCAAGCGACGTCTGATGCC ATCCTGCCCAGCCACCTGCTGGTCCAGCTCATGTCGCCAGTCCCGCAAATTCTTGAAGAGGCGCGACCGATACCC CTGCCGGACGATGAGATTGCAGATCGAGCCATCAGAGTTTTTGATCGAAATTCGAGTCTTGATGGCCACAAGGTG GGCGTCATCTACATTGGCGAGGGCCAGACGCAAGAGGCTGAGATCCTCGCGAACGTCTCCGGCAGCAGGGATTAT CTCGAGTTTCTCAACAACCTGGGGACGTTGACGAAGCTGAAGGGATCCACGTTCAACACGCAGGGCTTGGACCGT GAGTACGATTCGGATGGTCAGTACACCTTTTGCTGGCGGGACAGGGTGACGGAGATTGTGTTCCACGTGACGACG CAGATGCCTACCGACCTGGAGCGAGATCCAAACTGTACACTCAAGAAGAGACACATCGGCAACGACTTCGTCAAC ATCATCTTCAACGACTCGGCGCTTCCTTTTCAGTTTGAAACGTTCCCAAGTCAATTCAACTTTGTCAACATTGTC ATCACGCCGGCGTCGCGCGCTTCGTTCGTCGCCATGCGGACGCGGGGTGCGGATCGAGGTCAAAGCCAGAAACAG CCCTTCTACAGGGTCCAGGTGATGAGCAAGCCGGGTTTTCCGGAGGTGTCCCCGGCGTCGGAGACCAAGATGATA TCTCTGAAAGCACTCCCGGGCTTCATACGGCTCTTGGCACTCAACGCATCCATGTTTTCGGTAGTGTGGCACAAC CGGGAGGGAGGCGAGCACATCAGCTCGTGGAGCGCGAGGCTTCGGGAGATTAAACGCCTGCGGGAGAAGCATGGG CCGAAGGCGGCCACCACGGCCTCGTCGCCGCCGGCTTCATCGTGGCACGGTGGGGCCTCGCACGCTCAACAGGCG GATACGTCGCGGGCCGGCAGCAGCGTTCGGGATAGTTTCAGCAGCCTGCGTCGGACGAGCGTTGCGACCTTTTTT ACGAGCACGAGCGAGCAGATGTCTCATCGATCGTCGACACTATCCACGTCGGCTACTTCCCATGATACGGAGCTA CCGCCGACGGCGGCAGCAGCAAACACTTTGGTGGACTCGGTCGACTTCTCCAAGTGGGCATGA |
| Transcript | >Hirsu2|6409 ATGTCGGTCTGGCTCGATGCTGTCTTGGCAATCCTTCAAGGCAGTGACTGGGAGGTGTGCAGCTTCGTACTTGTC CATCTCCCGTCGCAGCTCAGCAATCATGCCATCTTCAGAGATGCGATCCCGCAGATTCAGGAACTTCGCAGGATC ATCTGTGAGCAGATCCGGACAAACGGCTTCCAAGAGCCGCCCAACGCTTCAGGGCTGCGACGAGCGGACGTGGCC ATCTGTCTCTTCCACAGCTTGACTATGATTCTTAGCTATCACGAGCACTTTCAGAAAAGCGATGAGGATGACATT GTAAAGACTTTCGCTCTCGGCATCGCCGCGTGGGAACGAACGGCGAAATACTGCATCCATGCGCTCTCTATTTGC TGCCACGAGCTCCCGCTCTCGACGAGCAAGTCGCTGATCCAGTTGCTGAATCAGATGGCTGCGATCATCACGCAG CCTCACGTTTCCGTCCACATCCTGGAGTTTCTCGCCTCCTTGAGCCGGCTTCACAACGTCTTTGTCAATTTCCGA GAGGACGACTACCGGATCGTCTTTGGCATTTGCTTCCGCTACTTGGAGTACGCCAAAGAGAAGAAGCAGTCCAAC CGCAGCAGCCACGTCAGCGAAGTGTCGACTCCGGGCTCGAACCACGCGGAACCCCCCAGCACGAGCCCTGCCGAT GAGCTTCCGCAATACGTCCATGCATTGGCCTATCACGTCATATTGTTCTGGTTCCTTGCTTTGAAGCTGCAGGAT CGGGCACACCACGTAGGGTGGATTGTCAAGAAACTCTTTTCGGATGCAGACGGGCACGGACCGGCGGCTGACGAC CAGACGCTCACAACGATCGACTTTATGCAAAGGGTCACTTTCGCAGACGTGGGCGAGTCTGCTGAAGACCCCTAC TTCAGCGAGGATCGCTTCGGCGCCATCGTCAAGAAACAGTGGCTGCTGGGCAACAGCATCGTAACGATCAAGCAG GCCACAGGGTCCGGGTGGGCTCAAGTTATCAAGAGACAGCCGTCGGGAACGTCGGCGTACATGGTTCGCGAGTCA TTCACGCCGACTCCGCCGCATCAGACAGCGGCCTACGTCGACGTGAGCCGGGAGGGCCAAGCGACGTCTGATGCC ATCCTGCCCAGCCACCTGCTGGTCCAGCTCATGTCGCCAGTCCCGCAAATTCTTGAAGAGGCGCGACCGATACCC CTGCCGGACGATGAGATTGCAGATCGAGCCATCAGAGTTTTTGATCGAAATTCGAGTCTTGATGGCCACAAGGTG GGCGTCATCTACATTGGCGAGGGCCAGACGCAAGAGGCTGAGATCCTCGCGAACGTCTCCGGCAGCAGGGATTAT CTCGAGTTTCTCAACAACCTGGGGACGTTGACGAAGCTGAAGGGATCCACGTTCAACACGCAGGGCTTGGACCGT GAGTACGATTCGGATGGTCAGTACACCTTTTGCTGGCGGGACAGGGTGACGGAGATTGTGTTCCACGTGACGACG CAGATGCCTACCGACCTGGAGCGAGATCCAAACTGTACACTCAAGAAGAGACACATCGGCAACGACTTCGTCAAC ATCATCTTCAACGACTCGGCGCTTCCTTTTCAGTTTGAAACGTTCCCAAGTCAATTCAACTTTGTCAACATTGTC ATCACGCCGGCGTCGCGCGCTTCGTTCGTCGCCATGCGGACGCGGGGTGCGGATCGAGGTCAAAGCCAGAAACAG CCCTTCTACAGGGTCCAGGTGATGAGCAAGCCGGGTTTTCCGGAGGTGTCCCCGGCGTCGGAGACCAAGATGATA TCTCTGAAAGCACTCCCGGGCTTCATACGGCTCTTGGCACTCAACGCATCCATGTTTTCGGTAGTGTGGCACAAC CGGGAGGGAGGCGAGCACATCAGCTCGTGGAGCGCGAGGCTTCGGGAGATTAAACGCCTGCGGGAGAAGCATGGG CCGAAGGCGGCCACCACGGCCTCGTCGCCGCCGGCTTCATCGTGGCACGGTGGGGCCTCGCACGCTCAACAGGCG GATACGTCGCGGGCCGGCAGCAGCGTTCGGGATAGTTTCAGCAGCCTGCGTCGGACGAGCGTTGCGACCTTTTTT ACGAGCACGAGCGAGCAGATGTCTCATCGATCGTCGACACTATCCACGTCGGCTACTTCCCATGATACGGAGCTA CCGCCGACGGCGGCAGCAGCAAACACTTTGGTGGACTCGGTCGACTTCTCCAAGTGGGCATGA |
| Gene | >Hirsu2|6409 ATGTCGGTCTGGCTCGATGCTGTCTTGGCAATCCTTCAAGGCAGTGACTGGGAGGTGTGCAGCTTCGTACTTGTC CATCTCCCGTCGCAGCTCAGCAATCATGCCATCTTCAGAGATGCGATCCCGCAGATTCAGGAACTTCGCAGGATC ATCTGTGAGCAGATCCGGACAAACGGCTTCCAAGAGCCGCCCAACGCTTCAGGGCTGCGACGAGCGGACGTGGCC ATCTGTCTCTTCCACAGCTTGACTATGATTCTTAGCTATCACGAGCACTTTCAGAAAAGCGATGAGGATGACATT GTAAAGACTTTCGCTCTCGGCATCGCCGCGTGGGAACGAACGGCGAAATACTGCATCCATGCGCTCTCTATTTGC TGCCACGAGCTCCCGCTCTCGACGAGCAAGTCGCTGATCCAGTTGCTGAATCAGATGGCTGCGATCATCACGCAG CCTCACGTTTCCGTCCACATCCTGGAGTTTCTCGCCTCCTTGAGCCGGCTTCACAACGTCTTTGTCAATTTCCGA GAGGACGACTACCGGATCGTCTTTGGCATTTGCTTCCGCTACTTGGAGTACGCCAAAGAGAAGAAGCAGTCCAAC CGCAGCAGCCACGTCAGCGAAGTGTCGACTCCGGGCTCGAACCACGCGGAACCCCCCAGCACGAGCCCTGCCGAT GAGCTTCCGCAATACGTCCATGCATTGGCCTATCACGTCATATTGTTCTGGTTCCTTGCTTTGAAGCTGCAGGAT CGGGCACACCACGTAGGGTGGATTGTCAAGAAACTCTTTTCGGATGCAGACGGGCACGGACCGGCGGCTGACGAC CAGACGCTCACAACGATCGACTTTATGCAAAGGGTCACTTTCGCAGACGTGGGCGAGTCTGCTGAAGACCCCTAC TTCAGCGAGGATCGCTTCGGCGCCATCGTCAAGAAACAGTGGCTGCTGGGCAACAGCATCGTAACGATCAAGCAG GCCACAGGGTCCGGGTGGGCTCAAGTTATCAAGAGACAGCCGTCGGGAACGTCGGCGTACATGGTTCGCGAGTCA TTCACGCCGACTCCGCCGCATCAGACAGCGGCCTACGTCGACGTGAGCCGGGAGGGCCAAGCGACGTCTGATGCC ATCCTGCCCAGCCACCTGCTGGTCCAGCTCATGTCGCCAGTCCCGCAAATTCTTGAAGAGGCGCGACCGATACCC CTGCCGGACGATGAGATTGCAGATCGAGCCATCAGAGTTTTTGATCGAAATTCGAGTCTTGATGGCCACAAGGTG GGCGTCATCTACATTGGCGAGGGCCAGACGCAAGAGGCTGAGATCCTCGCGAACGTCTCCGGCAGCAGGGATTAT CTCGAGTTTCTCAACAACCTGGGGACGTTGACGAAGCTGAAGGGATCCACGTTCAACACGCAGGGCTTGGACCGT GAGTACGATTCGGATGGTCAGTACACCTTTTGCTGGCGGGACAGGGTGACGGAGATTGTGTTCCACGTGACGACG CAGATGCCTACCGACCTGGAGCGAGATCCAAACTGTACACTCAAGAAGAGACACATCGGCAACGACTTCGTCAAC ATCATCTTCAACGACTCGGCGCTTCCTTTTCAGTTTGAAACGTTCCCAAGTCAATTCAACTTTGTCAACATTGTC ATCACGCCGGCGTCGCGCGCTTCGTTCGTCGCCATGCGGACGCGGGGTGCGGATCGAGGTCAAAGCCAGAAACAG CCCTTCTACAGGGTCCAGGTGATGAGCAAGCCGGGTTTTCCGGAGGTGTCCCCGGCGTCGGAGACCAAGATGATA TCTCTGAAAGCACTCCCGGGCTTCATACGGCTCTTGGCACTCAACGCATCCATGTTTTCGGTAGTGTGGCACAAC CGGGAGGGAGGCGAGCACATCAGCTCGTGGAGCGCGAGGCTTCGGGAGATTAAACGCCTGCGGGAGAAGCATGGG CCGAAGGCGGCCACCACGGCCTCGTCGCCGCCGGCTTCATCGTGGCACGGTGGGGCCTCGCACGCTCAACAGGCG GATACGTCGCGGGCCGGCAGCAGCGTTCGGGATAGTTTCAGCAGCCTGCGTCGGACGAGCGTTGCGACCTTTTTT ACGAGCACGAGCGAGCAGATGTCTCATCGATCGTCGACACTATCCACGTCGGCTACTTCCCATGATACGGAGCTA CCGCCGACGGCGGCAGCAGCAAACACTTTGGTGGACTCGGTCGACTTCTCCAAGTGGGCATGA |