© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|5734 |
| Gene name | |
| Location | Contig_289:3681..5293 |
| Strand | + |
| Gene length (bp) | 1612 |
| Transcript length (bp) | 1458 |
| Coding sequence length (bp) | 1458 |
| Protein length (aa) | 486 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF01222 | ERG4_ERG24 | Ergosterol biosynthesis ERG4/ERG24 family | 4.8E-169 | 15 | 485 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P38670|ERG24_NEUCR | Delta(14)-sterol reductase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=erg-3 PE=3 SV=1 | 3 | 485 | 0.0E+00 |
| sp|O13597|ERG24_SEPLY | Delta(14)-sterol reductase OS=Septoria lycopersici GN=ERG3 PE=3 SV=1 | 9 | 485 | 0.0E+00 |
| sp|Q01447|ERG24_FUSSO | Delta(14)-sterol reductase OS=Fusarium solani subsp. pisi PE=3 SV=1 | 1 | 485 | 0.0E+00 |
| sp|P78575|ERG24_ASCIM | Delta(14)-sterol reductase OS=Ascobolus immersus GN=ERG3 PE=3 SV=1 | 16 | 485 | 9.0E-131 |
| sp|Q09195|ERG24_SCHPO | Delta(14)-sterol reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg24 PE=2 SV=1 | 5 | 485 | 1.0E-118 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P38670|ERG24_NEUCR | Delta(14)-sterol reductase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN=erg-3 PE=3 SV=1 | 3 | 485 | 0.0E+00 |
| sp|O13597|ERG24_SEPLY | Delta(14)-sterol reductase OS=Septoria lycopersici GN=ERG3 PE=3 SV=1 | 9 | 485 | 0.0E+00 |
| sp|Q01447|ERG24_FUSSO | Delta(14)-sterol reductase OS=Fusarium solani subsp. pisi PE=3 SV=1 | 1 | 485 | 0.0E+00 |
| sp|P78575|ERG24_ASCIM | Delta(14)-sterol reductase OS=Ascobolus immersus GN=ERG3 PE=3 SV=1 | 16 | 485 | 9.0E-131 |
| sp|Q09195|ERG24_SCHPO | Delta(14)-sterol reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=erg24 PE=2 SV=1 | 5 | 485 | 1.0E-118 |
| sp|Q3U9G9|LBR_MOUSE | Lamin-B receptor OS=Mus musculus GN=Lbr PE=1 SV=2 | 10 | 485 | 2.0E-95 |
| sp|Q5R7H4|LBR_PONAB | Lamin-B receptor OS=Pongo abelii GN=LBR PE=2 SV=1 | 17 | 485 | 3.0E-94 |
| sp|Q14739|LBR_HUMAN | Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2 | 17 | 485 | 4.0E-94 |
| sp|O08984|LBR_RAT | Lamin-B receptor OS=Rattus norvegicus GN=Lbr PE=1 SV=1 | 1 | 485 | 1.0E-93 |
| sp|P32462|ERG24_YEAST | Delta(14)-sterol reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG24 PE=1 SV=1 | 7 | 485 | 1.0E-93 |
| sp|P23913|LBR_CHICK | Lamin-B receptor OS=Gallus gallus GN=LBR PE=1 SV=1 | 17 | 481 | 1.0E-89 |
| sp|O76062|ERG24_HUMAN | Delta(14)-sterol reductase OS=Homo sapiens GN=TM7SF2 PE=2 SV=3 | 100 | 485 | 3.0E-88 |
| sp|Q71KT5|ERG24_MOUSE | Delta(14)-sterol reductase OS=Mus musculus GN=Tm7sf2 PE=1 SV=2 | 100 | 485 | 4.0E-88 |
| sp|Q8WMV1|ERG24_BOVIN | Delta(14)-sterol reductase OS=Bos taurus GN=TM7SF2 PE=1 SV=1 | 100 | 485 | 9.0E-83 |
| sp|Q54PP1|ERG24_DICDI | Delta(14)-sterol reductase OS=Dictyostelium discoideum GN=erg24 PE=3 SV=1 | 17 | 484 | 3.0E-66 |
| sp|Q7SXF1|DHCR7_DANRE | 7-dehydrocholesterol reductase OS=Danio rerio GN=dhcr7 PE=2 SV=1 | 38 | 485 | 6.0E-64 |
| sp|Q7ZXH1|DHCR7_XENLA | 7-dehydrocholesterol reductase OS=Xenopus laevis GN=dhcr7 PE=2 SV=1 | 32 | 485 | 2.0E-62 |
| sp|Q5E9J5|DHCR7_BOVIN | 7-dehydrocholesterol reductase OS=Bos taurus GN=DHCR7 PE=2 SV=1 | 32 | 485 | 2.0E-61 |
| sp|Q6P4M0|DHCR7_XENTR | 7-dehydrocholesterol reductase OS=Xenopus tropicalis GN=dhcr7 PE=2 SV=1 | 32 | 485 | 4.0E-61 |
| sp|O88455|DHCR7_MOUSE | 7-dehydrocholesterol reductase OS=Mus musculus GN=Dhcr7 PE=1 SV=1 | 32 | 485 | 1.0E-60 |
| sp|Q9Z2Z8|DHCR7_RAT | 7-dehydrocholesterol reductase OS=Rattus norvegicus GN=Dhcr7 PE=2 SV=1 | 32 | 485 | 3.0E-60 |
| sp|Q9UBM7|DHCR7_HUMAN | 7-dehydrocholesterol reductase OS=Homo sapiens GN=DHCR7 PE=1 SV=1 | 32 | 485 | 1.0E-59 |
| sp|Q5UQI4|DHCR7_MIMIV | Probable 7-dehydrocholesterol reductase OS=Acanthamoeba polyphaga mimivirus GN=DHCR7 PE=3 SV=1 | 108 | 485 | 2.0E-55 |
| sp|Q9LDR4|ERG24_ARATH | Delta(14)-sterol reductase OS=Arabidopsis thaliana GN=FK PE=1 SV=2 | 78 | 485 | 2.0E-54 |
| sp|Q9LDU6|ST7R_ARATH | 7-dehydrocholesterol reductase OS=Arabidopsis thaliana GN=DWF5 PE=1 SV=1 | 74 | 485 | 8.0E-49 |
| sp|P25340|ERG4_YEAST | Delta(24(24(1)))-sterol reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERG4 PE=1 SV=2 | 10 | 485 | 1.0E-40 |
| sp|P36209|STS1_SCHPO | Delta(24(24(1)))-sterol reductase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sts1 PE=1 SV=2 | 1 | 485 | 8.0E-40 |
| sp|Q8MLV1|LBR_DROME | Lamin-B receptor OS=Drosophila melanogaster GN=LBR PE=1 SV=1 | 5 | 391 | 5.0E-13 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0016126 | sterol biosynthetic process | Yes |
| GO:0016020 | membrane | Yes |
| GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | Yes |
| GO:0016491 | oxidoreductase activity | No |
| GO:0008150 | biological_process | No |
| GO:1901615 | organic hydroxy compound metabolic process | No |
| GO:0009058 | biosynthetic process | No |
| GO:0003824 | catalytic activity | No |
| GO:0071704 | organic substance metabolic process | No |
| GO:0006694 | steroid biosynthetic process | No |
| GO:0006629 | lipid metabolic process | No |
| GO:0016125 | sterol metabolic process | No |
| GO:0008152 | metabolic process | No |
| GO:1901360 | organic cyclic compound metabolic process | No |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors | No |
| GO:1901362 | organic cyclic compound biosynthetic process | No |
| GO:0008202 | steroid metabolic process | No |
| GO:0008610 | lipid biosynthetic process | No |
| GO:0044238 | primary metabolic process | No |
| GO:0110165 | cellular anatomical entity | No |
| GO:1901617 | organic hydroxy compound biosynthetic process | No |
| GO:0003674 | molecular_function | No |
| GO:1901576 | organic substance biosynthetic process | No |
| GO:0005575 | cellular_component | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 40 | 0.5 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 18 | 40 | 22 |
| 2 | 124 | 143 | 19 |
| 3 | 158 | 180 | 22 |
| 4 | 250 | 269 | 19 |
| 5 | 289 | 308 | 19 |
| 6 | 320 | 339 | 19 |
| 7 | 433 | 452 | 19 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|5734 MPSSSKASASPAKHGYEFFGPPGAFGISFGLPLLVYVFALSCNDISGCPAPALLSPRTLSLSQLKLQVGWPGNGV WGLASWQATGALLGYYALNLILYRLLPASEVDGTVLSSGGRLKYRCNTLYSNTVTLAALAAGTMAQGADFPVWTF IDENYVQLLTASIGISYAISTFVYVRSFSVKPGDKQNRELAAGGHTGNLLYDWFIGRELNPRVTVPLIGELDIKE WCELRPGMMGWIVLNCAWCARQYRNYGYVTDSILCITIVQAVYTVDSWWNESAILTTMDITTDGFGMMLAFGDLV WVPFVYSLQTRYLSVHPRSLGPLGLLSMLTLIGLGFFIFRSANSQKNTFRTNPSDPSVSQLEYIETKTGSKLLTT GWWGVARHINYFGDWIQSWPYSLPTGLAGYQILAAGSGAEGAYVMRDGREVVSGNAEGWGMLTTYFYVVYFAILL IHRDRRDDEKCHRKYGEDWEKYKKIVRWRIIPGIY* |
| Coding | >Hirsu2|5734 ATGCCTTCCAGCTCCAAAGCCTCCGCCTCCCCGGCCAAGCACGGCTACGAGTTCTTCGGCCCTCCTGGCGCGTTT GGCATCTCGTTTGGCCTGCCCCTCCTCGTCTACGTCTTCGCCCTGTCCTGCAACGACATCTCTGGCTGTCCGGCT CCGGCCCTGCTCAGCCCGCGAACCCTCTCGCTCAGCCAGCTGAAGCTTCAGGTTGGCTGGCCCGGGAATGGCGTC TGGGGCCTCGCAAGCTGGCAGGCCACGGGGGCTTTGCTGGGCTACTACGCCCTCAACCTGATCCTCTACCGCCTC CTCCCCGCAAGCGAAGTAGACGGCACCGTACTGTCTTCGGGCGGCCGCCTCAAGTACCGGTGCAATACCTTGTAC TCCAACACCGTGACTCTCGCTGCCCTGGCCGCCGGTACCATGGCGCAGGGAGCCGACTTCCCTGTCTGGACCTTC ATCGACGAGAACTATGTGCAGCTGCTAACTGCCAGCATTGGCATCTCCTACGCCATCTCCACCTTTGTCTATGTC CGCAGCTTCAGCGTCAAGCCGGGAGACAAGCAGAACCGAGAGTTGGCGGCCGGCGGACACACCGGCAACCTGCTC TACGATTGGTTCATCGGGCGCGAGCTTAACCCCCGCGTCACCGTGCCTCTGATCGGTGAGCTTGACATCAAGGAG TGGTGCGAGCTGCGGCCCGGCATGATGGGCTGGATCGTCCTCAACTGCGCCTGGTGCGCCCGCCAGTACCGCAAC TACGGCTACGTGACAGACAGCATCCTGTGCATCACCATCGTGCAGGCCGTCTACACCGTCGACTCGTGGTGGAAC GAATCCGCCATTCTGACGACAATGGACATCACGACGGACGGATTTGGCATGATGCTGGCCTTTGGCGATCTCGTC TGGGTTCCCTTCGTCTACTCGCTGCAGACGCGCTACCTCTCCGTCCACCCCCGATCGCTCGGTCCCCTGGGCCTG CTGTCCATGCTGACGCTTATCGGCCTCGGCTTCTTCATCTTCCGCTCCGCCAACAGCCAGAAGAACACGTTCAGG ACGAACCCGAGCGACCCGAGCGTCTCCCAACTCGAGTACATCGAGACCAAGACGGGAAGCAAGCTCCTCACGACG GGATGGTGGGGGGTCGCCCGCCACATCAACTACTTCGGCGACTGGATCCAGTCGTGGCCGTACAGCCTGCCGACC GGGCTGGCTGGCTACCAGATCCTCGCCGCCGGCTCGGGCGCCGAGGGCGCCTACGTGATGAGGGACGGCCGCGAG GTTGTGTCGGGCAATGCAGAGGGCTGGGGCATGCTCACAACCTACTTTTACGTCGTCTACTTCGCCATTCTTCTC ATCCACCGCGACCGCCGCGACGACGAAAAATGCCACCGCAAATACGGCGAGGATTGGGAAAAGTACAAGAAGATT GTGCGGTGGCGCATCATCCCGGGCATCTACTAG |
| Transcript | >Hirsu2|5734 ATGCCTTCCAGCTCCAAAGCCTCCGCCTCCCCGGCCAAGCACGGCTACGAGTTCTTCGGCCCTCCTGGCGCGTTT GGCATCTCGTTTGGCCTGCCCCTCCTCGTCTACGTCTTCGCCCTGTCCTGCAACGACATCTCTGGCTGTCCGGCT CCGGCCCTGCTCAGCCCGCGAACCCTCTCGCTCAGCCAGCTGAAGCTTCAGGTTGGCTGGCCCGGGAATGGCGTC TGGGGCCTCGCAAGCTGGCAGGCCACGGGGGCTTTGCTGGGCTACTACGCCCTCAACCTGATCCTCTACCGCCTC CTCCCCGCAAGCGAAGTAGACGGCACCGTACTGTCTTCGGGCGGCCGCCTCAAGTACCGGTGCAATACCTTGTAC TCCAACACCGTGACTCTCGCTGCCCTGGCCGCCGGTACCATGGCGCAGGGAGCCGACTTCCCTGTCTGGACCTTC ATCGACGAGAACTATGTGCAGCTGCTAACTGCCAGCATTGGCATCTCCTACGCCATCTCCACCTTTGTCTATGTC CGCAGCTTCAGCGTCAAGCCGGGAGACAAGCAGAACCGAGAGTTGGCGGCCGGCGGACACACCGGCAACCTGCTC TACGATTGGTTCATCGGGCGCGAGCTTAACCCCCGCGTCACCGTGCCTCTGATCGGTGAGCTTGACATCAAGGAG TGGTGCGAGCTGCGGCCCGGCATGATGGGCTGGATCGTCCTCAACTGCGCCTGGTGCGCCCGCCAGTACCGCAAC TACGGCTACGTGACAGACAGCATCCTGTGCATCACCATCGTGCAGGCCGTCTACACCGTCGACTCGTGGTGGAAC GAATCCGCCATTCTGACGACAATGGACATCACGACGGACGGATTTGGCATGATGCTGGCCTTTGGCGATCTCGTC TGGGTTCCCTTCGTCTACTCGCTGCAGACGCGCTACCTCTCCGTCCACCCCCGATCGCTCGGTCCCCTGGGCCTG CTGTCCATGCTGACGCTTATCGGCCTCGGCTTCTTCATCTTCCGCTCCGCCAACAGCCAGAAGAACACGTTCAGG ACGAACCCGAGCGACCCGAGCGTCTCCCAACTCGAGTACATCGAGACCAAGACGGGAAGCAAGCTCCTCACGACG GGATGGTGGGGGGTCGCCCGCCACATCAACTACTTCGGCGACTGGATCCAGTCGTGGCCGTACAGCCTGCCGACC GGGCTGGCTGGCTACCAGATCCTCGCCGCCGGCTCGGGCGCCGAGGGCGCCTACGTGATGAGGGACGGCCGCGAG GTTGTGTCGGGCAATGCAGAGGGCTGGGGCATGCTCACAACCTACTTTTACGTCGTCTACTTCGCCATTCTTCTC ATCCACCGCGACCGCCGCGACGACGAAAAATGCCACCGCAAATACGGCGAGGATTGGGAAAAGTACAAGAAGATT GTGCGGTGGCGCATCATCCCGGGCATCTACTAG |
| Gene | >Hirsu2|5734 ATGCCTTCCAGCTCCAAAGCCTCCGCCTCCCCGGCCAAGCACGGCTACGAGTTCTTCGGCCCGTAAGTCGTCCCG ACTCTGCTGGCATCTTATCGCGTCTTCCTGGCTGTTCGTCATCATCGAAGCAGCTTGCTGACCAGCTGCTCGCCT CAAAGTCCTGGCGCGTTTGGCATCTCGTTTGGCCTGCCCCTCCTCGTCTACGTCTTCGCCCTGTCCTGCAACGAC ATCTCTGGCTGTCCGGCTCCGGCCCTGCTCAGCCCGCGAACCCTCTCGCTCAGCCAGCTGAAGCTTCAGGTTGGC TGGCCCGGGAATGGCGTCTGGGGCCTCGCAAGCTGGCAGGCCACGGGGGCTTTGCTGGGCTACTACGCCCTCAAC CTGATCCTCTACCGCCTCCTCCCCGCAAGCGAAGTAGACGGCACCGTACTGTCTTCGGGCGGCCGCCTCAAGTAC CGGTGCAATAGTGAGTAGCTCCCCCGTCGGGCCCCTCGTCGGTACTGCGTCCTGACCGACTCTCATCGCAGCCTT GTACTCCAACACCGTGACTCTCGCTGCCCTGGCCGCCGGTACCATGGCGCAGGGAGCCGACTTCCCTGTCTGGAC CTTCATCGACGAGAACTATGTGCAGCTGCTAACTGCCAGCATTGGCATCTCCTACGCCATCTCCACCTTTGTCTA TGTCCGCAGCTTCAGCGTCAAGCCGGGAGACAAGCAGAACCGAGAGTTGGCGGCCGGCGGACACACCGGCAACCT GCTCTACGATTGGTTCATCGGGCGCGAGCTTAACCCCCGCGTCACCGTGCCTCTGATCGGTGAGCTTGACATCAA GGAGTGGTGCGAGCTGCGGCCCGGCATGATGGGCTGGATCGTCCTCAACTGCGCCTGGTGCGCCCGCCAGTACCG CAACTACGGCTACGTGACAGACAGCATCCTGTGCATCACCATCGTGCAGGCCGTCTACACCGTCGACTCGTGGTG GAACGAATCCGCCATTCTGACGACAATGGACATCACGACGGACGGATTTGGCATGATGCTGGCCTTTGGCGATCT CGTCTGGGTTCCCTTCGTCTACTCGCTGCAGACGCGCTACCTCTCCGTCCACCCCCGATCGCTCGGTCCCCTGGG CCTGCTGTCCATGCTGACGCTTATCGGCCTCGGCTTCTTCATCTTCCGCTCCGCCAACAGCCAGAAGAACACGTT CAGGACGAACCCGAGCGACCCGAGCGTCTCCCAACTCGAGTACATCGAGACCAAGACGGGAAGCAAGCTCCTCAC GACGGGATGGTGGGGGGTCGCCCGCCACATCAACTACTTCGGCGACTGGATCCAGTCGTGGCCGTACAGCCTGCC GACCGGGCTGGCTGGCTACCAGATCCTCGCCGCCGGCTCGGGCGCCGAGGGCGCCTACGTGATGAGGGACGGCCG CGAGGTTGTGTCGGGCAATGCAGAGGGCTGGGGCATGCTCACAACCTACTTTTACGTCGTCTACTTCGCCATTCT TCTCATCCACCGCGACCGCCGCGACGACGAAAAATGCCACCGCAAATACGGCGAGGATTGGGAAAAGTACAAGAA GATTGTGCGGTGGCGCATCATCCCGGGCATCTACTAG |