Fungal Genomics

at Utrecht University

General Properties

Protein IDHirsu2|5579
Gene name
LocationContig_28:29942..31043
Strand+
Gene length (bp)1101
Transcript length (bp)1101
Coding sequence length (bp)1101
Protein length (aa) 367

Overview

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PFAM Domains

PFAM Domain ID Short name Long name E-value Start End
PF02219 MTHFR Methylenetetrahydrofolate reductase 1.0E-79 51 351

Swissprot hits

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Swissprot ID Swissprot Description Start End E-value
sp|O74927|MTHR2_SCHPO Methylenetetrahydrofolate reductase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=met11 PE=1 SV=2 41 365 2.0E-63
sp|P46151|MTHR1_YEAST Methylenetetrahydrofolate reductase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET12 PE=1 SV=2 55 356 2.0E-63
sp|O80585|MTHR2_ARATH Methylenetetrahydrofolate reductase 2 OS=Arabidopsis thaliana GN=MTHFR2 PE=1 SV=2 41 361 3.0E-51
sp|P53128|MTHR2_YEAST Methylenetetrahydrofolate reductase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET13 PE=1 SV=2 41 318 5.0E-51
sp|Q75HE6|MTHR_ORYSJ Probable methylenetetrahydrofolate reductase OS=Oryza sativa subsp. japonica GN=Os03g0815200 PE=2 SV=1 41 361 4.0E-50
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Swissprot ID Swissprot Description Start End E-value
sp|O74927|MTHR2_SCHPO Methylenetetrahydrofolate reductase 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=met11 PE=1 SV=2 41 365 2.0E-63
sp|P46151|MTHR1_YEAST Methylenetetrahydrofolate reductase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET12 PE=1 SV=2 55 356 2.0E-63
sp|O80585|MTHR2_ARATH Methylenetetrahydrofolate reductase 2 OS=Arabidopsis thaliana GN=MTHFR2 PE=1 SV=2 41 361 3.0E-51
sp|P53128|MTHR2_YEAST Methylenetetrahydrofolate reductase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET13 PE=1 SV=2 41 318 5.0E-51
sp|Q75HE6|MTHR_ORYSJ Probable methylenetetrahydrofolate reductase OS=Oryza sativa subsp. japonica GN=Os03g0815200 PE=2 SV=1 41 361 4.0E-50
sp|Q9SE94|MTHR1_MAIZE Methylenetetrahydrofolate reductase 1 OS=Zea mays PE=2 SV=1 41 361 5.0E-50
sp|Q10258|MTHR1_SCHPO Methylenetetrahydrofolate reductase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=met9 PE=1 SV=1 56 354 2.0E-49
sp|Q9SE60|MTHR1_ARATH Methylenetetrahydrofolate reductase 1 OS=Arabidopsis thaliana GN=MTHFR1 PE=1 SV=1 41 361 2.0E-49
sp|O67422|METF_AQUAE 5,10-methylenetetrahydrofolate reductase OS=Aquifex aeolicus (strain VF5) GN=metF PE=3 SV=1 57 341 5.0E-48
sp|Q5I598|MTHR_BOVIN Methylenetetrahydrofolate reductase OS=Bos taurus GN=MTHFR PE=2 SV=1 35 354 7.0E-45
sp|P42898|MTHR_HUMAN Methylenetetrahydrofolate reductase OS=Homo sapiens GN=MTHFR PE=1 SV=3 35 350 1.0E-44
sp|Q60HE5|MTHR_MACFA Methylenetetrahydrofolate reductase OS=Macaca fascicularis GN=MTHFR PE=2 SV=1 55 350 2.0E-44
sp|Q9WU20|MTHR_MOUSE Methylenetetrahydrofolate reductase OS=Mus musculus GN=Mthfr PE=1 SV=2 33 351 2.0E-43
sp|Q17693|MTHR_CAEEL Probable methylenetetrahydrofolate reductase OS=Caenorhabditis elegans GN=mthf-1 PE=3 SV=2 55 354 4.0E-40
sp|P71319|METF_PECCC 5,10-methylenetetrahydrofolate reductase OS=Pectobacterium carotovorum subsp. carotovorum GN=metF PE=3 SV=1 57 343 3.0E-34
sp|P45208|METF_HAEIN 5,10-methylenetetrahydrofolate reductase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=metF PE=3 SV=1 51 343 2.0E-32
sp|Q9JZQ3|METF_NEIMB 5,10-methylenetetrahydrofolate reductase OS=Neisseria meningitidis serogroup B (strain MC58) GN=metF PE=1 SV=1 57 343 1.0E-30
sp|O54235|METF_STRLI 5,10-methylenetetrahydrofolate reductase OS=Streptomyces lividans GN=metF PE=3 SV=1 56 354 2.0E-30
sp|P11003|METF_SALTY 5,10-methylenetetrahydrofolate reductase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=metF PE=3 SV=2 57 343 4.0E-30
sp|P0AEZ2|METF_SHIFL 5,10-methylenetetrahydrofolate reductase OS=Shigella flexneri GN=metF PE=3 SV=1 57 343 4.0E-29
sp|P0AEZ1|METF_ECOLI 5,10-methylenetetrahydrofolate reductase OS=Escherichia coli (strain K12) GN=metF PE=1 SV=1 57 343 4.0E-29
sp|P57154|METF_BUCAI 5,10-methylenetetrahydrofolate reductase OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) GN=metF PE=3 SV=1 57 348 4.0E-28
sp|Q89B13|METF_BUCBP 5,10-methylenetetrahydrofolate reductase OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp) GN=metF PE=3 SV=1 57 351 7.0E-26
sp|Q8KA62|METF_BUCAP 5,10-methylenetetrahydrofolate reductase OS=Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) GN=metF PE=3 SV=1 57 348 3.0E-25
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GO

GO Term Description Terminal node
GO:0006555 methionine metabolic process Yes
GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity Yes
GO:0008152 metabolic process No
GO:0008150 biological_process No
GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor No
GO:0006520 cellular amino acid metabolic process No
GO:0003824 catalytic activity No
GO:0071704 organic substance metabolic process No
GO:0006082 organic acid metabolic process No
GO:1901605 alpha-amino acid metabolic process No
GO:0006790 sulfur compound metabolic process No
GO:0009987 cellular process No
GO:0009066 aspartate family amino acid metabolic process No
GO:0043436 oxoacid metabolic process No
GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors No
GO:0016491 oxidoreductase activity No
GO:0006807 nitrogen compound metabolic process No
GO:0000096 sulfur amino acid metabolic process No
GO:0044238 primary metabolic process No
GO:0019752 carboxylic acid metabolic process No
GO:1901564 organonitrogen compound metabolic process No
GO:0044281 small molecule metabolic process No
GO:0003674 molecular_function No
GO:0044237 cellular metabolic process No

Deeploc

[Help with interpreting the results of Deeploc 2.0]
Localizations Signals Cytoplasm Nucleus Extracellular Cell membrane Mitochondrion Plastid Endoplasmic reticulum Lysosome vacuole Golgi apparatus Peroxisome
Cytoplasm 0.5364 0.2399 0.0926 0.0555 0.4783 0.0094 0.1348 0.2066 0.2806 0.0205

SignalP

(None)

Transmembrane Domains

(None)

Transcription Factor Class

(None)

CAZymes

(None)

Secondary Metabolism

(None)

Expression data

No expression data available for this genome

Orthologs

Orthofinder run ID4
Orthogroup503
Change Orthofinder run
Species Protein ID
Ophiocordyceps australis 1348a (Ghana) OphauG2|1626
Ophiocordyceps australis 1348a (Ghana) OphauG2|6038
Ophiocordyceps australis map64 (Brazil) OphauB2|5839
Ophiocordyceps camponoti-floridani Ophcf2|04845
Ophiocordyceps camponoti-rufipedis Ophun1|5393
Ophiocordyceps kimflemingae Ophio5|8357
Ophiocordyceps subramaniannii Hirsu2|1555
Ophiocordyceps subramaniannii Hirsu2|5579 (this protein)

Sequences

Type of sequenceSequence
Locus Download genbank file of locus Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein >Hirsu2|5579
MPGLDDGPATTSGLRIFGAGEGLQSTLDQGFHAADVASSQKITEKIAALPHDADFFSLEFFPPKTKNGTANLRAR
IVRMKHALQPLFVSITWGAGGSSFNQSFDLAEKCQRELGLTTLLHLTTVDMTRQTLDRALARARALGIRNIMALK
GDRPRDGSDPAAGHAANDAAVRQDFFWAVDLVRYIRKAHGNYFNIGVAAYPEGHFNASDPSSRGVEHDLPFLAEK
VEAGADFIMTQLFYDMDAYADFESKVRAYPSEALKKIPIIPGILPIPSQRRFDNTLKLAHATVPDIIRAQLDPVR
KNNTEWMTAGERVVTDLVGAIHERASKRPGPRGYSFFTLNQEEPVSTVLKNTHLASGARKSGASDA*
Coding >Hirsu2|5579
ATGCCGGGCCTCGACGATGGCCCGGCGACGACGTCCGGTCTGCGCATCTTCGGTGCCGGAGAGGGCCTTCAGAGC
ACGCTGGACCAGGGTTTCCACGCCGCCGACGTGGCCTCGTCGCAGAAGATCACCGAAAAGATCGCCGCCCTGCCG
CACGACGCCGACTTCTTCTCCCTCGAGTTCTTCCCGCCCAAGACCAAAAACGGCACCGCCAACCTACGCGCGCGC
ATCGTTCGCATGAAGCATGCGCTCCAGCCGCTCTTCGTCAGCATCACCTGGGGCGCAGGCGGCTCCTCCTTCAAC
CAGTCCTTTGATCTGGCCGAGAAATGCCAGCGAGAGCTGGGCCTCACCACCCTGCTGCACCTCACCACCGTCGAC
ATGACTCGGCAGACTCTCGATAGGGCGTTGGCACGTGCCCGTGCGCTGGGGATCCGCAACATCATGGCCCTCAAG
GGCGACCGGCCGCGAGACGGCTCGGATCCGGCCGCTGGCCACGCCGCGAACGATGCGGCCGTACGGCAAGACTTC
TTCTGGGCGGTCGACCTTGTGCGGTATATCCGGAAAGCCCACGGCAACTACTTCAACATCGGGGTCGCGGCTTAC
CCCGAGGGGCACTTCAACGCGAGCGACCCGTCGAGCCGGGGCGTCGAGCACGATTTGCCGTTCCTCGCCGAGAAG
GTCGAGGCCGGGGCCGACTTTATCATGACCCAGCTTTTCTACGACATGGACGCCTATGCGGACTTCGAGAGCAAG
GTGCGGGCGTATCCCAGCGAGGCCCTGAAAAAGATCCCCATCATTCCTGGCATCCTACCCATCCCGAGCCAGAGA
AGATTCGACAACACGCTGAAGCTGGCCCACGCCACCGTACCCGACATCATCCGGGCGCAGCTTGACCCGGTGAGA
AAGAACAACACGGAGTGGATGACAGCTGGTGAGCGTGTAGTGACCGACCTGGTCGGAGCGATTCACGAGCGCGCG
AGCAAGCGGCCTGGCCCCAGAGGGTACTCCTTCTTCACGTTGAATCAGGAGGAGCCGGTGTCGACGGTTCTGAAG
AATACCCACCTGGCCTCCGGTGCTAGAAAGTCGGGGGCTAGTGACGCTTAG
Transcript >Hirsu2|5579
ATGCCGGGCCTCGACGATGGCCCGGCGACGACGTCCGGTCTGCGCATCTTCGGTGCCGGAGAGGGCCTTCAGAGC
ACGCTGGACCAGGGTTTCCACGCCGCCGACGTGGCCTCGTCGCAGAAGATCACCGAAAAGATCGCCGCCCTGCCG
CACGACGCCGACTTCTTCTCCCTCGAGTTCTTCCCGCCCAAGACCAAAAACGGCACCGCCAACCTACGCGCGCGC
ATCGTTCGCATGAAGCATGCGCTCCAGCCGCTCTTCGTCAGCATCACCTGGGGCGCAGGCGGCTCCTCCTTCAAC
CAGTCCTTTGATCTGGCCGAGAAATGCCAGCGAGAGCTGGGCCTCACCACCCTGCTGCACCTCACCACCGTCGAC
ATGACTCGGCAGACTCTCGATAGGGCGTTGGCACGTGCCCGTGCGCTGGGGATCCGCAACATCATGGCCCTCAAG
GGCGACCGGCCGCGAGACGGCTCGGATCCGGCCGCTGGCCACGCCGCGAACGATGCGGCCGTACGGCAAGACTTC
TTCTGGGCGGTCGACCTTGTGCGGTATATCCGGAAAGCCCACGGCAACTACTTCAACATCGGGGTCGCGGCTTAC
CCCGAGGGGCACTTCAACGCGAGCGACCCGTCGAGCCGGGGCGTCGAGCACGATTTGCCGTTCCTCGCCGAGAAG
GTCGAGGCCGGGGCCGACTTTATCATGACCCAGCTTTTCTACGACATGGACGCCTATGCGGACTTCGAGAGCAAG
GTGCGGGCGTATCCCAGCGAGGCCCTGAAAAAGATCCCCATCATTCCTGGCATCCTACCCATCCCGAGCCAGAGA
AGATTCGACAACACGCTGAAGCTGGCCCACGCCACCGTACCCGACATCATCCGGGCGCAGCTTGACCCGGTGAGA
AAGAACAACACGGAGTGGATGACAGCTGGTGAGCGTGTAGTGACCGACCTGGTCGGAGCGATTCACGAGCGCGCG
AGCAAGCGGCCTGGCCCCAGAGGGTACTCCTTCTTCACGTTGAATCAGGAGGAGCCGGTGTCGACGGTTCTGAAG
AATACCCACCTGGCCTCCGGTGCTAGAAAGTCGGGGGCTAGTGACGCTTAG
Gene >Hirsu2|5579
ATGCCGGGCCTCGACGATGGCCCGGCGACGACGTCCGGTCTGCGCATCTTCGGTGCCGGAGAGGGCCTTCAGAGC
ACGCTGGACCAGGGTTTCCACGCCGCCGACGTGGCCTCGTCGCAGAAGATCACCGAAAAGATCGCCGCCCTGCCG
CACGACGCCGACTTCTTCTCCCTCGAGTTCTTCCCGCCCAAGACCAAAAACGGCACCGCCAACCTACGCGCGCGC
ATCGTTCGCATGAAGCATGCGCTCCAGCCGCTCTTCGTCAGCATCACCTGGGGCGCAGGCGGCTCCTCCTTCAAC
CAGTCCTTTGATCTGGCCGAGAAATGCCAGCGAGAGCTGGGCCTCACCACCCTGCTGCACCTCACCACCGTCGAC
ATGACTCGGCAGACTCTCGATAGGGCGTTGGCACGTGCCCGTGCGCTGGGGATCCGCAACATCATGGCCCTCAAG
GGCGACCGGCCGCGAGACGGCTCGGATCCGGCCGCTGGCCACGCCGCGAACGATGCGGCCGTACGGCAAGACTTC
TTCTGGGCGGTCGACCTTGTGCGGTATATCCGGAAAGCCCACGGCAACTACTTCAACATCGGGGTCGCGGCTTAC
CCCGAGGGGCACTTCAACGCGAGCGACCCGTCGAGCCGGGGCGTCGAGCACGATTTGCCGTTCCTCGCCGAGAAG
GTCGAGGCCGGGGCCGACTTTATCATGACCCAGCTTTTCTACGACATGGACGCCTATGCGGACTTCGAGAGCAAG
GTGCGGGCGTATCCCAGCGAGGCCCTGAAAAAGATCCCCATCATTCCTGGCATCCTACCCATCCCGAGCCAGAGA
AGATTCGACAACACGCTGAAGCTGGCCCACGCCACCGTACCCGACATCATCCGGGCGCAGCTTGACCCGGTGAGA
AAGAACAACACGGAGTGGATGACAGCTGGTGAGCGTGTAGTGACCGACCTGGTCGGAGCGATTCACGAGCGCGCG
AGCAAGCGGCCTGGCCCCAGAGGGTACTCCTTCTTCACGTTGAATCAGGAGGAGCCGGTGTCGACGGTTCTGAAG
AATACCCACCTGGCCTCCGGTGCTAGAAAGTCGGGGGCTAGTGACGCTTAG

© 2023 - Robin Ohm - Utrecht University - The Netherlands

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