© 2022 - Robin Ohm - Utrecht University - The Netherlands
Built with Python Django and Wagtail
| Protein ID | Hirsu2|5087 |
| Gene name | |
| Location | Contig_255:6373..9232 |
| Strand | - |
| Gene length (bp) | 2859 |
| Transcript length (bp) | 2859 |
| Coding sequence length (bp) | 2859 |
| Protein length (aa) | 953 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF18368 | Ig_GlcNase | Exo-beta-D-glucosaminidase Ig-fold domain | 3.7E-30 | 783 | 896 |
| PF00703 | Glyco_hydro_2 | Glycosyl hydrolases family 2 | 4.2E-11 | 229 | 333 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q4R1C4|EBDG_HYPJE | Exo-beta-D-glucosaminidase OS=Hypocrea jecorina GN=gls93 PE=1 SV=1 | 18 | 903 | 0.0E+00 |
| sp|D4AUH1|EBDG_ARTBC | Exo-beta-D-glucosaminidase ARB_07888 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_07888 PE=1 SV=1 | 13 | 901 | 0.0E+00 |
| sp|C0LRA7|EBDG_HYPVI | Exo-beta-D-glucosaminidase OS=Hypocrea virens GN=gls1 PE=2 SV=1 | 7 | 903 | 0.0E+00 |
| sp|Q82NR8|EBDG_STRAW | Exo-beta-D-glucosaminidase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) GN=csxA PE=1 SV=1 | 28 | 901 | 3.0E-177 |
| sp|Q56F26|EBDG_AMYOR | Exo-beta-D-glucosaminidase OS=Amycolatopsis orientalis GN=csxA PE=1 SV=2 | 39 | 905 | 4.0E-174 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q4R1C4|EBDG_HYPJE | Exo-beta-D-glucosaminidase OS=Hypocrea jecorina GN=gls93 PE=1 SV=1 | 18 | 903 | 0.0E+00 |
| sp|D4AUH1|EBDG_ARTBC | Exo-beta-D-glucosaminidase ARB_07888 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_07888 PE=1 SV=1 | 13 | 901 | 0.0E+00 |
| sp|C0LRA7|EBDG_HYPVI | Exo-beta-D-glucosaminidase OS=Hypocrea virens GN=gls1 PE=2 SV=1 | 7 | 903 | 0.0E+00 |
| sp|Q82NR8|EBDG_STRAW | Exo-beta-D-glucosaminidase OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) GN=csxA PE=1 SV=1 | 28 | 901 | 3.0E-177 |
| sp|Q56F26|EBDG_AMYOR | Exo-beta-D-glucosaminidase OS=Amycolatopsis orientalis GN=csxA PE=1 SV=2 | 39 | 905 | 4.0E-174 |
| sp|Q75W54|EBM_ARATH | Mannosylglycoprotein endo-beta-mannosidase OS=Arabidopsis thaliana GN=EBM PE=1 SV=3 | 42 | 881 | 8.0E-37 |
| sp|Q5H7P5|EBM_LILLO | Mannosylglycoprotein endo-beta-mannosidase OS=Lilium longiflorum GN=EBM PE=1 SV=4 | 76 | 879 | 3.0E-30 |
| sp|Q0CCA0|MANBB_ASPTN | Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=mndB PE=3 SV=2 | 110 | 674 | 5.0E-16 |
| sp|Q29444|MANBA_BOVIN | Beta-mannosidase OS=Bos taurus GN=MANBA PE=1 SV=1 | 192 | 664 | 8.0E-15 |
| sp|A1CGA8|MANBB_ASPCL | Beta-mannosidase B OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=mndB PE=3 SV=1 | 110 | 674 | 2.0E-14 |
| sp|Q8K2I4|MANBA_MOUSE | Beta-mannosidase OS=Mus musculus GN=Manba PE=1 SV=1 | 110 | 711 | 3.0E-14 |
| sp|I2C092|MANBB_THIHE | Beta-mannosidase B OS=Thielavia heterothallica GN=man9 PE=1 SV=1 | 110 | 675 | 3.0E-14 |
| sp|Q5B7W2|MANBB_EMENI | Beta-mannosidase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=mndB PE=1 SV=2 | 110 | 674 | 3.0E-14 |
| sp|Q2TXB7|MANBB_ASPOR | Beta-mannosidase B OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) GN=mndB PE=3 SV=3 | 110 | 674 | 5.0E-14 |
| sp|B8NW36|MANBB_ASPFN | Beta-mannosidase B OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) GN=mndB PE=3 SV=1 | 110 | 674 | 5.0E-14 |
| sp|Q4FZV0|MANBA_RAT | Beta-mannosidase OS=Rattus norvegicus GN=Manba PE=2 SV=1 | 110 | 664 | 1.0E-13 |
| sp|A2QYN2|MANBB_ASPNC | Beta-mannosidase B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=mndB PE=3 SV=1 | 278 | 674 | 2.0E-13 |
| sp|O00462|MANBA_HUMAN | Beta-mannosidase OS=Homo sapiens GN=MANBA PE=2 SV=3 | 79 | 664 | 4.0E-13 |
| sp|A1D911|MANBB_NEOFI | Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) GN=mndB PE=3 SV=1 | 110 | 674 | 7.0E-12 |
| sp|Q95327|MANBA_CAPHI | Beta-mannosidase OS=Capra hircus GN=MANBA PE=2 SV=1 | 192 | 664 | 1.0E-11 |
| sp|Q4WAH4|MANBB_ASPFU | Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=mndB PE=3 SV=1 | 110 | 674 | 2.0E-10 |
| sp|B0YBU9|MANBB_ASPFC | Beta-mannosidase B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=mndB PE=3 SV=1 | 110 | 674 | 3.0E-10 |
| sp|A7LXS9|BGH2A_BACO1 | Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / NCTC 11153) GN=BACOVA_02645 PE=1 SV=1 | 112 | 484 | 1.0E-07 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | Yes |
| GO:0005975 | carbohydrate metabolic process | Yes |
| GO:0016798 | hydrolase activity, acting on glycosyl bonds | No |
| GO:0071704 | organic substance metabolic process | No |
| GO:0008152 | metabolic process | No |
| GO:0003824 | catalytic activity | No |
| GO:0044238 | primary metabolic process | No |
| GO:0008150 | biological_process | No |
| GO:0016787 | hydrolase activity | No |
| GO:0003674 | molecular_function | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| Yes | 1 - 27 | 0.45 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|5087 MPFPTTMFGYTFAILLLGHACKAASAQTRATSLAEKLIIPHWDLQSSAKVDRDLARVSQPGYDSSSWYHIQQSRC TLMGCLLAAGVYNDSNLWFSDNLRHFDTSLFSVPWVYRNEFSLAPTDGQHYLLETNGVTSKADIYLNGDQIANKD TQVGSFGGHTYDVTGLVSRRNALVISAHPGDFSYDLIQGFVDWNPSPPDNATGIWRDIYLRQTGPVSMGPASVSI EMNTDVPLEDTSARVTVRAKAQNLVDHKVQLVVRSIVTDPTGRDNICEPVVVELSPGEFQLIEMDHQIDNPEIWW PKQWGGQPLYKSELIFWVNSRVSDSSRQSFGIRTVTSGVNSHNDTLFTINGRPFQVIGGGYAPDHFFRWDRQRFL AIARYTLDMGLNTIRLEGTLEHPELYEIADELGIMIMAGWVCCSKWEAWKYNTDLQLDPFPLWVDRDYETANASM IHEAAMLQSHPSILAFLVGSDSWPNDRATKIYVDALKGAHWQTPVIASAAKRGYPELLGPSGLKMDGPYDWVPPS YWYDTEPTKERLGAAFGFGSELGAGVGTPEYGSLKKFLAQKDLEDLWMRPEMDLFHMSANKSAFKNRRIYNEALF QKYGPPTSLKDYLLKSQIMDYEATRAQHEGYASRWNAERPATGTIYWMLNNAWPALHWNLFDYAMHPAGSYFGAK TAGRIQHVAYDYVDHSIWLINRSLHRSEACQVAVELIDLGGKVLSTQTLQALSKANTATKVGIVEGVGEVDQVAF LRLILNGEEATLSRNVYWITKAVDTLEWKNSTWRHTPVSKFADFTSLSKMETARIRLTSPYPNTKRTCNVGKIDQ EWRSLELENESSVPAFFIRLNLIDEMGDDVNPVIWSDNYITMWPREKITLEVNYAGGRVQDLAVEVSGGNIESSI VHFNGPTKNNFDREPHIASAVPSRSTGDSRCPKDAIKEKGEKKDRSRLLNPM* |
| Coding | >Hirsu2|5087 ATGCCCTTTCCCACGACCATGTTTGGATACACGTTTGCGATCCTCCTCCTCGGCCATGCCTGCAAAGCGGCCTCT GCCCAGACCCGCGCGACCTCTCTGGCAGAGAAATTAATCATCCCACATTGGGACCTGCAGTCGTCGGCAAAAGTC GACCGGGACCTCGCTCGAGTCTCCCAACCCGGCTACGACAGCTCATCGTGGTATCATATACAACAATCGCGCTGC ACGCTTATGGGATGTCTCCTGGCGGCAGGCGTCTACAATGACTCGAATCTTTGGTTCTCCGACAATCTCAGACAT TTCGACACCAGCCTGTTCTCCGTGCCTTGGGTTTACAGGAACGAGTTCTCGCTTGCGCCGACTGATGGGCAGCAC TATTTACTAGAGACGAACGGGGTTACTTCTAAAGCGGATATATACCTGAATGGCGATCAAATTGCGAACAAGGAT ACTCAGGTTGGATCTTTTGGCGGTCACACATACGACGTCACGGGCCTGGTGAGCCGCCGTAACGCGCTCGTAATT AGCGCACATCCCGGCGACTTCAGCTATGATCTGATACAAGGGTTTGTCGACTGGAACCCGTCACCTCCCGACAAT GCGACCGGAATCTGGCGAGACATCTACCTCAGGCAGACAGGCCCTGTGTCCATGGGCCCGGCAAGTGTGTCGATT GAAATGAACACGGACGTGCCTCTGGAGGACACTTCGGCCAGGGTTACTGTGCGCGCAAAGGCCCAGAACCTTGTC GATCACAAGGTGCAGCTCGTGGTTCGCTCGATCGTTACGGATCCTACTGGTCGCGACAATATCTGCGAGCCTGTC GTCGTAGAGCTGAGTCCTGGAGAGTTTCAACTCATCGAAATGGACCATCAAATAGACAACCCCGAGATATGGTGG CCGAAGCAGTGGGGCGGGCAACCATTGTACAAATCCGAGCTGATCTTCTGGGTCAATTCAAGGGTCTCCGACTCG TCTCGACAATCCTTTGGGATCCGAACGGTTACATCAGGTGTAAACAGTCACAATGACACACTTTTCACAATCAAC GGTCGACCTTTCCAGGTTATCGGCGGTGGCTATGCACCGGATCACTTTTTTCGGTGGGATAGACAGCGGTTTCTA GCCATCGCGAGGTACACTCTCGATATGGGACTCAATACCATTAGGCTCGAGGGAACACTCGAACACCCCGAGCTA TATGAGATTGCTGACGAGCTGGGAATCATGATCATGGCTGGCTGGGTCTGTTGCTCCAAGTGGGAGGCATGGAAG TATAACACCGACTTGCAGCTTGACCCCTTTCCACTCTGGGTGGATAGGGATTATGAAACGGCTAATGCCAGTATG ATCCACGAAGCAGCGATGCTTCAGAGCCACCCGAGCATCTTGGCTTTCCTTGTCGGGAGCGACTCCTGGCCTAAT GATCGGGCGACCAAGATCTACGTTGACGCGCTCAAGGGTGCGCACTGGCAAACTCCCGTCATTGCCTCAGCTGCC AAACGCGGATATCCGGAGTTACTGGGCCCAAGCGGCTTGAAAATGGACGGCCCTTATGACTGGGTTCCCCCCAGC TACTGGTACGATACGGAACCGACGAAAGAAAGATTAGGGGCTGCTTTCGGGTTTGGCTCTGAGCTGGGCGCTGGT GTGGGAACCCCAGAATACGGCAGCCTTAAGAAGTTTCTCGCGCAGAAAGATTTGGAGGATCTCTGGATGCGACCG GAAATGGACCTCTTTCACATGTCTGCAAACAAGTCCGCCTTCAAAAACCGGAGAATCTACAACGAGGCACTGTTT CAGAAATATGGCCCGCCAACGTCTTTGAAGGACTACTTGCTCAAGTCTCAGATTATGGACTATGAGGCCACCCGA GCGCAGCACGAAGGGTACGCATCGCGATGGAATGCCGAGCGCCCAGCCACCGGGACGATCTACTGGATGCTCAAC AATGCTTGGCCGGCACTTCACTGGAATCTGTTCGACTATGCCATGCATCCCGCCGGATCTTACTTTGGTGCCAAA ACAGCCGGCAGGATTCAGCATGTTGCCTACGACTACGTGGACCACAGTATCTGGCTCATCAATCGATCTCTCCAT AGGTCCGAGGCATGCCAGGTCGCCGTGGAGCTGATCGATCTTGGTGGCAAAGTTTTGTCTACGCAAACTCTGCAA GCCCTCAGCAAGGCGAATACAGCAACTAAGGTCGGGATAGTAGAGGGCGTTGGGGAGGTCGACCAGGTGGCCTTC TTGCGACTAATTCTTAATGGGGAAGAGGCTACCTTGAGTCGCAACGTTTACTGGATCACGAAGGCCGTTGATACG CTGGAATGGAAGAATTCAACTTGGCGCCATACTCCAGTTTCCAAGTTCGCCGATTTCACGTCCCTCTCCAAAATG GAAACGGCTCGCATACGCCTCACCTCGCCGTATCCAAACACAAAGCGTACATGTAACGTGGGCAAGATCGACCAG GAGTGGCGATCGCTCGAACTCGAGAATGAGTCATCAGTTCCTGCGTTTTTCATTCGCCTAAACTTGATTGATGAG ATGGGAGACGACGTTAACCCGGTCATCTGGTCGGATAACTACATCACGATGTGGCCACGAGAGAAAATTACGCTC GAGGTTAACTACGCAGGTGGTAGGGTTCAAGACTTGGCCGTGGAAGTCAGCGGAGGAAACATCGAATCCTCCATC GTTCACTTCAACGGACCAACGAAGAACAATTTCGACCGCGAGCCTCACATCGCGAGCGCCGTGCCTTCAAGGTCG ACCGGAGACAGCAGATGCCCAAAGGATGCCATCAAAGAAAAAGGGGAGAAAAAAGACCGCTCCCGGTTATTAAAT CCTATGTGA |
| Transcript | >Hirsu2|5087 ATGCCCTTTCCCACGACCATGTTTGGATACACGTTTGCGATCCTCCTCCTCGGCCATGCCTGCAAAGCGGCCTCT GCCCAGACCCGCGCGACCTCTCTGGCAGAGAAATTAATCATCCCACATTGGGACCTGCAGTCGTCGGCAAAAGTC GACCGGGACCTCGCTCGAGTCTCCCAACCCGGCTACGACAGCTCATCGTGGTATCATATACAACAATCGCGCTGC ACGCTTATGGGATGTCTCCTGGCGGCAGGCGTCTACAATGACTCGAATCTTTGGTTCTCCGACAATCTCAGACAT TTCGACACCAGCCTGTTCTCCGTGCCTTGGGTTTACAGGAACGAGTTCTCGCTTGCGCCGACTGATGGGCAGCAC TATTTACTAGAGACGAACGGGGTTACTTCTAAAGCGGATATATACCTGAATGGCGATCAAATTGCGAACAAGGAT ACTCAGGTTGGATCTTTTGGCGGTCACACATACGACGTCACGGGCCTGGTGAGCCGCCGTAACGCGCTCGTAATT AGCGCACATCCCGGCGACTTCAGCTATGATCTGATACAAGGGTTTGTCGACTGGAACCCGTCACCTCCCGACAAT GCGACCGGAATCTGGCGAGACATCTACCTCAGGCAGACAGGCCCTGTGTCCATGGGCCCGGCAAGTGTGTCGATT GAAATGAACACGGACGTGCCTCTGGAGGACACTTCGGCCAGGGTTACTGTGCGCGCAAAGGCCCAGAACCTTGTC GATCACAAGGTGCAGCTCGTGGTTCGCTCGATCGTTACGGATCCTACTGGTCGCGACAATATCTGCGAGCCTGTC GTCGTAGAGCTGAGTCCTGGAGAGTTTCAACTCATCGAAATGGACCATCAAATAGACAACCCCGAGATATGGTGG CCGAAGCAGTGGGGCGGGCAACCATTGTACAAATCCGAGCTGATCTTCTGGGTCAATTCAAGGGTCTCCGACTCG TCTCGACAATCCTTTGGGATCCGAACGGTTACATCAGGTGTAAACAGTCACAATGACACACTTTTCACAATCAAC GGTCGACCTTTCCAGGTTATCGGCGGTGGCTATGCACCGGATCACTTTTTTCGGTGGGATAGACAGCGGTTTCTA GCCATCGCGAGGTACACTCTCGATATGGGACTCAATACCATTAGGCTCGAGGGAACACTCGAACACCCCGAGCTA TATGAGATTGCTGACGAGCTGGGAATCATGATCATGGCTGGCTGGGTCTGTTGCTCCAAGTGGGAGGCATGGAAG TATAACACCGACTTGCAGCTTGACCCCTTTCCACTCTGGGTGGATAGGGATTATGAAACGGCTAATGCCAGTATG ATCCACGAAGCAGCGATGCTTCAGAGCCACCCGAGCATCTTGGCTTTCCTTGTCGGGAGCGACTCCTGGCCTAAT GATCGGGCGACCAAGATCTACGTTGACGCGCTCAAGGGTGCGCACTGGCAAACTCCCGTCATTGCCTCAGCTGCC AAACGCGGATATCCGGAGTTACTGGGCCCAAGCGGCTTGAAAATGGACGGCCCTTATGACTGGGTTCCCCCCAGC TACTGGTACGATACGGAACCGACGAAAGAAAGATTAGGGGCTGCTTTCGGGTTTGGCTCTGAGCTGGGCGCTGGT GTGGGAACCCCAGAATACGGCAGCCTTAAGAAGTTTCTCGCGCAGAAAGATTTGGAGGATCTCTGGATGCGACCG GAAATGGACCTCTTTCACATGTCTGCAAACAAGTCCGCCTTCAAAAACCGGAGAATCTACAACGAGGCACTGTTT CAGAAATATGGCCCGCCAACGTCTTTGAAGGACTACTTGCTCAAGTCTCAGATTATGGACTATGAGGCCACCCGA GCGCAGCACGAAGGGTACGCATCGCGATGGAATGCCGAGCGCCCAGCCACCGGGACGATCTACTGGATGCTCAAC AATGCTTGGCCGGCACTTCACTGGAATCTGTTCGACTATGCCATGCATCCCGCCGGATCTTACTTTGGTGCCAAA ACAGCCGGCAGGATTCAGCATGTTGCCTACGACTACGTGGACCACAGTATCTGGCTCATCAATCGATCTCTCCAT AGGTCCGAGGCATGCCAGGTCGCCGTGGAGCTGATCGATCTTGGTGGCAAAGTTTTGTCTACGCAAACTCTGCAA GCCCTCAGCAAGGCGAATACAGCAACTAAGGTCGGGATAGTAGAGGGCGTTGGGGAGGTCGACCAGGTGGCCTTC TTGCGACTAATTCTTAATGGGGAAGAGGCTACCTTGAGTCGCAACGTTTACTGGATCACGAAGGCCGTTGATACG CTGGAATGGAAGAATTCAACTTGGCGCCATACTCCAGTTTCCAAGTTCGCCGATTTCACGTCCCTCTCCAAAATG GAAACGGCTCGCATACGCCTCACCTCGCCGTATCCAAACACAAAGCGTACATGTAACGTGGGCAAGATCGACCAG GAGTGGCGATCGCTCGAACTCGAGAATGAGTCATCAGTTCCTGCGTTTTTCATTCGCCTAAACTTGATTGATGAG ATGGGAGACGACGTTAACCCGGTCATCTGGTCGGATAACTACATCACGATGTGGCCACGAGAGAAAATTACGCTC GAGGTTAACTACGCAGGTGGTAGGGTTCAAGACTTGGCCGTGGAAGTCAGCGGAGGAAACATCGAATCCTCCATC GTTCACTTCAACGGACCAACGAAGAACAATTTCGACCGCGAGCCTCACATCGCGAGCGCCGTGCCTTCAAGGTCG ACCGGAGACAGCAGATGCCCAAAGGATGCCATCAAAGAAAAAGGGGAGAAAAAAGACCGCTCCCGGTTATTAAAT CCTATGTGA |
| Gene | >Hirsu2|5087 ATGCCCTTTCCCACGACCATGTTTGGATACACGTTTGCGATCCTCCTCCTCGGCCATGCCTGCAAAGCGGCCTCT GCCCAGACCCGCGCGACCTCTCTGGCAGAGAAATTAATCATCCCACATTGGGACCTGCAGTCGTCGGCAAAAGTC GACCGGGACCTCGCTCGAGTCTCCCAACCCGGCTACGACAGCTCATCGTGGTATCATATACAACAATCGCGCTGC ACGCTTATGGGATGTCTCCTGGCGGCAGGCGTCTACAATGACTCGAATCTTTGGTTCTCCGACAATCTCAGACAT TTCGACACCAGCCTGTTCTCCGTGCCTTGGGTTTACAGGAACGAGTTCTCGCTTGCGCCGACTGATGGGCAGCAC TATTTACTAGAGACGAACGGGGTTACTTCTAAAGCGGATATATACCTGAATGGCGATCAAATTGCGAACAAGGAT ACTCAGGTTGGATCTTTTGGCGGTCACACATACGACGTCACGGGCCTGGTGAGCCGCCGTAACGCGCTCGTAATT AGCGCACATCCCGGCGACTTCAGCTATGATCTGATACAAGGGTTTGTCGACTGGAACCCGTCACCTCCCGACAAT GCGACCGGAATCTGGCGAGACATCTACCTCAGGCAGACAGGCCCTGTGTCCATGGGCCCGGCAAGTGTGTCGATT GAAATGAACACGGACGTGCCTCTGGAGGACACTTCGGCCAGGGTTACTGTGCGCGCAAAGGCCCAGAACCTTGTC GATCACAAGGTGCAGCTCGTGGTTCGCTCGATCGTTACGGATCCTACTGGTCGCGACAATATCTGCGAGCCTGTC GTCGTAGAGCTGAGTCCTGGAGAGTTTCAACTCATCGAAATGGACCATCAAATAGACAACCCCGAGATATGGTGG CCGAAGCAGTGGGGCGGGCAACCATTGTACAAATCCGAGCTGATCTTCTGGGTCAATTCAAGGGTCTCCGACTCG TCTCGACAATCCTTTGGGATCCGAACGGTTACATCAGGTGTAAACAGTCACAATGACACACTTTTCACAATCAAC GGTCGACCTTTCCAGGTTATCGGCGGTGGCTATGCACCGGATCACTTTTTTCGGTGGGATAGACAGCGGTTTCTA GCCATCGCGAGGTACACTCTCGATATGGGACTCAATACCATTAGGCTCGAGGGAACACTCGAACACCCCGAGCTA TATGAGATTGCTGACGAGCTGGGAATCATGATCATGGCTGGCTGGGTCTGTTGCTCCAAGTGGGAGGCATGGAAG TATAACACCGACTTGCAGCTTGACCCCTTTCCACTCTGGGTGGATAGGGATTATGAAACGGCTAATGCCAGTATG ATCCACGAAGCAGCGATGCTTCAGAGCCACCCGAGCATCTTGGCTTTCCTTGTCGGGAGCGACTCCTGGCCTAAT GATCGGGCGACCAAGATCTACGTTGACGCGCTCAAGGGTGCGCACTGGCAAACTCCCGTCATTGCCTCAGCTGCC AAACGCGGATATCCGGAGTTACTGGGCCCAAGCGGCTTGAAAATGGACGGCCCTTATGACTGGGTTCCCCCCAGC TACTGGTACGATACGGAACCGACGAAAGAAAGATTAGGGGCTGCTTTCGGGTTTGGCTCTGAGCTGGGCGCTGGT GTGGGAACCCCAGAATACGGCAGCCTTAAGAAGTTTCTCGCGCAGAAAGATTTGGAGGATCTCTGGATGCGACCG GAAATGGACCTCTTTCACATGTCTGCAAACAAGTCCGCCTTCAAAAACCGGAGAATCTACAACGAGGCACTGTTT CAGAAATATGGCCCGCCAACGTCTTTGAAGGACTACTTGCTCAAGTCTCAGATTATGGACTATGAGGCCACCCGA GCGCAGCACGAAGGGTACGCATCGCGATGGAATGCCGAGCGCCCAGCCACCGGGACGATCTACTGGATGCTCAAC AATGCTTGGCCGGCACTTCACTGGAATCTGTTCGACTATGCCATGCATCCCGCCGGATCTTACTTTGGTGCCAAA ACAGCCGGCAGGATTCAGCATGTTGCCTACGACTACGTGGACCACAGTATCTGGCTCATCAATCGATCTCTCCAT AGGTCCGAGGCATGCCAGGTCGCCGTGGAGCTGATCGATCTTGGTGGCAAAGTTTTGTCTACGCAAACTCTGCAA GCCCTCAGCAAGGCGAATACAGCAACTAAGGTCGGGATAGTAGAGGGCGTTGGGGAGGTCGACCAGGTGGCCTTC TTGCGACTAATTCTTAATGGGGAAGAGGCTACCTTGAGTCGCAACGTTTACTGGATCACGAAGGCCGTTGATACG CTGGAATGGAAGAATTCAACTTGGCGCCATACTCCAGTTTCCAAGTTCGCCGATTTCACGTCCCTCTCCAAAATG GAAACGGCTCGCATACGCCTCACCTCGCCGTATCCAAACACAAAGCGTACATGTAACGTGGGCAAGATCGACCAG GAGTGGCGATCGCTCGAACTCGAGAATGAGTCATCAGTTCCTGCGTTTTTCATTCGCCTAAACTTGATTGATGAG ATGGGAGACGACGTTAACCCGGTCATCTGGTCGGATAACTACATCACGATGTGGCCACGAGAGAAAATTACGCTC GAGGTTAACTACGCAGGTGGTAGGGTTCAAGACTTGGCCGTGGAAGTCAGCGGAGGAAACATCGAATCCTCCATC GTTCACTTCAACGGACCAACGAAGAACAATTTCGACCGCGAGCCTCACATCGCGAGCGCCGTGCCTTCAAGGTCG ACCGGAGACAGCAGATGCCCAAAGGATGCCATCAAAGAAAAAGGGGAGAAAAAAGACCGCTCCCGGTTATTAAAT CCTATGTGA |