© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|4865 |
| Gene name | |
| Location | Contig_245:4576..6429 |
| Strand | - |
| Gene length (bp) | 1853 |
| Transcript length (bp) | 1758 |
| Coding sequence length (bp) | 1758 |
| Protein length (aa) | 586 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF00067 | p450 | Cytochrome P450 | 6.6E-26 | 61 | 557 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O75881|CP7B1_HUMAN | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Homo sapiens GN=CYP7B1 PE=1 SV=2 | 60 | 536 | 8.0E-19 |
| sp|Q60991|CP7B1_MOUSE | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Mus musculus GN=Cyp7b1 PE=2 SV=2 | 66 | 536 | 1.0E-16 |
| sp|Q63688|CP7B1_RAT | 25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) OS=Rattus norvegicus GN=Cyp7b1 PE=1 SV=1 | 218 | 536 | 3.0E-16 |
| sp|Q9UNU6|CP8B1_HUMAN | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase OS=Homo sapiens GN=CYP8B1 PE=1 SV=2 | 30 | 536 | 5.0E-16 |
| sp|O46491|CP7A1_PIG | Cholesterol 7-alpha-monooxygenase OS=Sus scrofa GN=CYP7A1 PE=3 SV=1 | 60 | 542 | 7.0E-16 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|O75881|CP7B1_HUMAN | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Homo sapiens GN=CYP7B1 PE=1 SV=2 | 60 | 536 | 8.0E-19 |
| sp|Q60991|CP7B1_MOUSE | 25-hydroxycholesterol 7-alpha-hydroxylase OS=Mus musculus GN=Cyp7b1 PE=2 SV=2 | 66 | 536 | 1.0E-16 |
| sp|Q63688|CP7B1_RAT | 25-hydroxycholesterol 7-alpha-hydroxylase (Fragment) OS=Rattus norvegicus GN=Cyp7b1 PE=1 SV=1 | 218 | 536 | 3.0E-16 |
| sp|Q9UNU6|CP8B1_HUMAN | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase OS=Homo sapiens GN=CYP8B1 PE=1 SV=2 | 30 | 536 | 5.0E-16 |
| sp|O46491|CP7A1_PIG | Cholesterol 7-alpha-monooxygenase OS=Sus scrofa GN=CYP7A1 PE=3 SV=1 | 60 | 542 | 7.0E-16 |
| sp|P18125|CP7A1_RAT | Cholesterol 7-alpha-monooxygenase OS=Rattus norvegicus GN=Cyp7a1 PE=1 SV=1 | 306 | 542 | 2.0E-15 |
| sp|P46634|CP7A1_CRIGR | Cholesterol 7-alpha-monooxygenase OS=Cricetulus griseus GN=CYP7A1 PE=3 SV=1 | 306 | 542 | 3.0E-15 |
| sp|Q7YRB2|CP8B1_PIG | 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase OS=Sus scrofa GN=CYP8B1 PE=2 SV=1 | 60 | 536 | 5.0E-15 |
| sp|Q64505|CP7A1_MOUSE | Cholesterol 7-alpha-monooxygenase OS=Mus musculus GN=Cyp7a1 PE=2 SV=2 | 60 | 542 | 2.0E-14 |
| sp|P22680|CP7A1_HUMAN | Cholesterol 7-alpha-monooxygenase OS=Homo sapiens GN=CYP7A1 PE=1 SV=2 | 336 | 542 | 4.0E-14 |
| sp|O88962|CP8B1_MOUSE | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase OS=Mus musculus GN=Cyp8b1 PE=1 SV=1 | 60 | 536 | 1.0E-13 |
| sp|P51542|CP7A1_RABIT | Cholesterol 7-alpha-monooxygenase OS=Oryctolagus cuniculus GN=CYP7A1 PE=1 SV=1 | 313 | 542 | 2.0E-13 |
| sp|O02766|CP8B1_RABIT | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase OS=Oryctolagus cuniculus GN=CYP8B1 PE=1 SV=3 | 60 | 536 | 6.0E-12 |
| sp|O81972|C82A2_SOYBN | Cytochrome P450 82A2 OS=Glycine max GN=CYP82A2 PE=2 SV=1 | 47 | 572 | 4.0E-09 |
| sp|P51871|CP4F6_RAT | Cytochrome P450 4F6 OS=Rattus norvegicus GN=Cyp4f6 PE=2 SV=1 | 14 | 537 | 4.0E-09 |
| sp|C0SJS3|ANGS_PASSA | Angelicin synthase (Fragment) OS=Pastinaca sativa GN=CYP71AJ4 PE=1 SV=1 | 220 | 544 | 3.0E-08 |
| sp|Q9VVR9|C12C1_DROME | Probable cytochrome P450 12c1, mitochondrial OS=Drosophila melanogaster GN=Cyp12c1 PE=2 SV=2 | 245 | 563 | 4.0E-08 |
| sp|O15528|CP27B_HUMAN | 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial OS=Homo sapiens GN=CYP27B1 PE=1 SV=1 | 261 | 564 | 1.0E-07 |
| sp|O35074|PTGIS_MOUSE | Prostacyclin synthase OS=Mus musculus GN=Ptgis PE=1 SV=1 | 316 | 536 | 2.0E-07 |
| sp|P30608|CP52F_CANTR | Cytochrome P450 52A6 OS=Candida tropicalis GN=CYP52A6 PE=2 SV=1 | 354 | 521 | 3.0E-07 |
| sp|C0SJS2|C71AJ_PASSA | Psoralen synthase (Fragment) OS=Pastinaca sativa GN=CYP71AJ3 PE=1 SV=1 | 220 | 560 | 3.0E-07 |
| sp|Q4G0S4|C27C1_HUMAN | Cytochrome P450 27C1 OS=Homo sapiens GN=CYP27C1 PE=2 SV=2 | 408 | 570 | 4.0E-07 |
| sp|Q62969|PTGIS_RAT | Prostacyclin synthase OS=Rattus norvegicus GN=Ptgis PE=2 SV=1 | 316 | 536 | 5.0E-07 |
| sp|P9WPN2|CP132_MYCTO | Putative cytochrome P450 132 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=cyp132 PE=3 SV=1 | 341 | 569 | 5.0E-07 |
| sp|P59954|CP132_MYCBO | Putative cytochrome P450 132 OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) GN=cyp132 PE=3 SV=1 | 341 | 569 | 5.0E-07 |
| sp|P9WPN3|CP132_MYCTU | Putative cytochrome P450 132 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=cyp132 PE=1 SV=1 | 341 | 569 | 6.0E-07 |
| sp|Q7KR10|CCD1D_DROME | Probable cytochrome P450 12d1 distal, mitochondrial OS=Drosophila melanogaster GN=Cyp12d1-d PE=2 SV=1 | 412 | 536 | 1.0E-06 |
| sp|Q07973|CP24A_HUMAN | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial OS=Homo sapiens GN=CYP24A1 PE=1 SV=2 | 346 | 536 | 1.0E-06 |
| sp|P82712|CCD1P_DROME | Probable cytochrome P450 12d1 proximal, mitochondrial OS=Drosophila melanogaster GN=Cyp12d1-p PE=2 SV=3 | 412 | 536 | 1.0E-06 |
| sp|Q07217|CP11A_ONCMY | Cholesterol side-chain cleavage enzyme, mitochondrial OS=Oncorhynchus mykiss GN=cyp11a1 PE=2 SV=1 | 331 | 525 | 2.0E-06 |
| sp|P10615|CP52A_CANTR | Cytochrome P450 52A1 OS=Candida tropicalis GN=CYP52A1 PE=1 SV=3 | 354 | 521 | 2.0E-06 |
| sp|Q9DBG1|CP27A_MOUSE | Sterol 26-hydroxylase, mitochondrial OS=Mus musculus GN=Cyp27a1 PE=1 SV=1 | 343 | 535 | 2.0E-06 |
| sp|P24458|CP52E_CANMA | Cytochrome P450 52A3-B OS=Candida maltosa GN=CYP52A3-B PE=1 SV=1 | 354 | 521 | 3.0E-06 |
| sp|P30610|CP52H_CANTR | Cytochrome P450 52A8 OS=Candida tropicalis GN=CYP52A8 PE=2 SV=1 | 341 | 538 | 3.0E-06 |
| sp|P93149|C93B1_GLYEC | Licodione synthase OS=Glycyrrhiza echinata GN=CYP93B1 PE=1 SV=2 | 357 | 541 | 4.0E-06 |
| sp|Q02318|CP27A_HUMAN | Sterol 26-hydroxylase, mitochondrial OS=Homo sapiens GN=CYP27A1 PE=1 SV=1 | 334 | 541 | 5.0E-06 |
| sp|P48416|CP10_LYMST | Cytochrome P450 10 OS=Lymnaea stagnalis GN=CYP10 PE=2 SV=1 | 357 | 532 | 7.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0004497 | monooxygenase activity | Yes |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Yes |
| GO:0005506 | iron ion binding | Yes |
| GO:0020037 | heme binding | Yes |
| GO:0016491 | oxidoreductase activity | No |
| GO:0046906 | tetrapyrrole binding | No |
| GO:0003824 | catalytic activity | No |
| GO:0046872 | metal ion binding | No |
| GO:0046914 | transition metal ion binding | No |
| GO:0097159 | organic cyclic compound binding | No |
| GO:0005488 | binding | No |
| GO:0043167 | ion binding | No |
| GO:1901363 | heterocyclic compound binding | No |
| GO:0043169 | cation binding | No |
| GO:0003674 | molecular_function | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 47 | 0.5 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|4865 MATQTLLPLGSDFGSEFLTPWVPQPAVLTLLATIVVILATAKLVLPGSSTPGDDGCRSCPPKVPFWVPFFGHAPQ MFANSDGFLARLRDRYPQGVFSLRLCGKLHHFVHGPSMATTLLNRPKTAAESVSNNLLVSNFGFTKKDQAHHATM AAESKANFQFLLSEPGLGDLVQETVAHVKLNIADLVTFNSSPADQMDWEWEAGAEVVSGPRGDSFVQADLMELTR NFIAKTANCALYGTDFVQNFADIWRLMWAFDDAFFLLATRIPGWVPWPRLQRAKAAQRRILSYTREFSEAMDKHI QGQDPGAKWQDLDNVSALVKARHQTFRKHGLSMEARASCDLALCWAMNANANQLVPWMLFELYRDPVLLEQVREE IAPYVQVRQPENDFGMAVWLPPVLEKIDLEGLISRCPLLKAAYIETLRVYTGTWTMRRLNEDVVLGDRGKAEPYL LRKGTYAHVSQEMHQFDPEYFPNPREWHHERHLREQDDDEGRRTVVADMGTVRPYGGGPAMCKGRAFALREMLLY SAIIISFYDMQPPSGQSWEHAPKTYKTVATRHPKAPIKVWIRRREQPVEGQEKSEDAGTA* |
| Coding | >Hirsu2|4865 ATGGCGACACAGACTCTCCTGCCACTCGGCTCCGATTTCGGCTCCGAGTTTCTCACACCTTGGGTACCGCAGCCT GCCGTCCTCACCCTGCTGGCCACGATTGTCGTCATCCTTGCCACCGCAAAGCTCGTCCTGCCTGGATCGTCGACA CCCGGCGACGATGGCTGCAGATCGTGTCCGCCCAAGGTTCCCTTCTGGGTCCCCTTTTTCGGCCATGCGCCTCAG ATGTTCGCCAATTCGGACGGATTCCTGGCGAGACTGCGCGACCGCTATCCCCAGGGCGTCTTCTCCCTGCGGCTG TGCGGCAAGTTGCACCACTTCGTCCACGGACCGTCCATGGCCACCACGCTGCTCAACCGGCCCAAGACGGCGGCC GAGTCTGTCTCGAACAACCTGCTCGTCTCCAACTTCGGCTTCACCAAGAAAGACCAGGCCCATCACGCCACCATG GCGGCAGAGTCCAAGGCGAACTTCCAGTTCCTACTTTCCGAGCCCGGCCTCGGCGACCTTGTCCAGGAGACTGTG GCCCATGTCAAGCTGAACATTGCCGACCTCGTCACGTTCAATTCCAGTCCTGCCGACCAGATGGACTGGGAGTGG GAGGCTGGCGCCGAGGTCGTCAGCGGGCCCCGCGGTGATTCCTTCGTCCAGGCCGATCTCATGGAGCTGACCCGA AACTTCATCGCCAAGACGGCCAACTGTGCTCTTTACGGTACCGACTTCGTTCAGAACTTCGCCGACATCTGGCGG CTCATGTGGGCCTTTGACGACGCCTTCTTCCTGCTGGCCACGAGGATCCCCGGATGGGTGCCCTGGCCGCGGCTG CAGCGGGCCAAGGCTGCGCAGAGACGGATCCTCAGCTACACGCGCGAATTCAGCGAAGCCATGGACAAGCACATC CAAGGCCAGGACCCCGGCGCCAAGTGGCAGGACCTGGACAACGTCAGTGCCCTCGTCAAGGCCCGACACCAGACT TTCCGCAAGCACGGGCTGTCCATGGAGGCGCGGGCCAGCTGCGACCTGGCCCTGTGCTGGGCCATGAACGCAAAC GCCAACCAGCTCGTCCCTTGGATGCTGTTTGAGCTGTACCGGGATCCCGTGCTCCTCGAGCAGGTCCGGGAAGAG ATAGCTCCATACGTCCAGGTGAGGCAGCCCGAGAACGATTTCGGCATGGCCGTCTGGTTGCCGCCGGTCCTCGAA AAGATCGACCTCGAGGGCCTGATCAGCCGGTGCCCACTCCTCAAAGCGGCCTATATCGAGACGCTTCGGGTGTAC ACGGGCACCTGGACCATGAGGCGGCTCAATGAGGACGTGGTGCTCGGCGACCGAGGCAAGGCGGAACCGTATCTG CTGCGAAAGGGCACGTACGCCCATGTTTCCCAAGAGATGCACCAGTTTGATCCGGAGTACTTCCCCAACCCTCGG GAATGGCACCACGAAAGACACCTGAGAGAGCAGGATGACGACGAGGGGCGAAGGACGGTAGTGGCCGACATGGGC ACGGTGAGGCCATACGGCGGAGGCCCGGCCATGTGTAAGGGACGAGCCTTTGCGCTGCGCGAGATGTTGCTGTAC TCGGCCATCATCATCTCTTTCTATGACATGCAGCCACCGAGCGGGCAGAGCTGGGAACACGCGCCCAAGACGTAC AAAACAGTGGCCACGAGGCATCCCAAAGCGCCAATCAAGGTGTGGATCAGGAGACGAGAGCAGCCGGTGGAAGGA CAAGAAAAGAGTGAGGATGCCGGCACGGCGTAG |
| Transcript | >Hirsu2|4865 ATGGCGACACAGACTCTCCTGCCACTCGGCTCCGATTTCGGCTCCGAGTTTCTCACACCTTGGGTACCGCAGCCT GCCGTCCTCACCCTGCTGGCCACGATTGTCGTCATCCTTGCCACCGCAAAGCTCGTCCTGCCTGGATCGTCGACA CCCGGCGACGATGGCTGCAGATCGTGTCCGCCCAAGGTTCCCTTCTGGGTCCCCTTTTTCGGCCATGCGCCTCAG ATGTTCGCCAATTCGGACGGATTCCTGGCGAGACTGCGCGACCGCTATCCCCAGGGCGTCTTCTCCCTGCGGCTG TGCGGCAAGTTGCACCACTTCGTCCACGGACCGTCCATGGCCACCACGCTGCTCAACCGGCCCAAGACGGCGGCC GAGTCTGTCTCGAACAACCTGCTCGTCTCCAACTTCGGCTTCACCAAGAAAGACCAGGCCCATCACGCCACCATG GCGGCAGAGTCCAAGGCGAACTTCCAGTTCCTACTTTCCGAGCCCGGCCTCGGCGACCTTGTCCAGGAGACTGTG GCCCATGTCAAGCTGAACATTGCCGACCTCGTCACGTTCAATTCCAGTCCTGCCGACCAGATGGACTGGGAGTGG GAGGCTGGCGCCGAGGTCGTCAGCGGGCCCCGCGGTGATTCCTTCGTCCAGGCCGATCTCATGGAGCTGACCCGA AACTTCATCGCCAAGACGGCCAACTGTGCTCTTTACGGTACCGACTTCGTTCAGAACTTCGCCGACATCTGGCGG CTCATGTGGGCCTTTGACGACGCCTTCTTCCTGCTGGCCACGAGGATCCCCGGATGGGTGCCCTGGCCGCGGCTG CAGCGGGCCAAGGCTGCGCAGAGACGGATCCTCAGCTACACGCGCGAATTCAGCGAAGCCATGGACAAGCACATC CAAGGCCAGGACCCCGGCGCCAAGTGGCAGGACCTGGACAACGTCAGTGCCCTCGTCAAGGCCCGACACCAGACT TTCCGCAAGCACGGGCTGTCCATGGAGGCGCGGGCCAGCTGCGACCTGGCCCTGTGCTGGGCCATGAACGCAAAC GCCAACCAGCTCGTCCCTTGGATGCTGTTTGAGCTGTACCGGGATCCCGTGCTCCTCGAGCAGGTCCGGGAAGAG ATAGCTCCATACGTCCAGGTGAGGCAGCCCGAGAACGATTTCGGCATGGCCGTCTGGTTGCCGCCGGTCCTCGAA AAGATCGACCTCGAGGGCCTGATCAGCCGGTGCCCACTCCTCAAAGCGGCCTATATCGAGACGCTTCGGGTGTAC ACGGGCACCTGGACCATGAGGCGGCTCAATGAGGACGTGGTGCTCGGCGACCGAGGCAAGGCGGAACCGTATCTG CTGCGAAAGGGCACGTACGCCCATGTTTCCCAAGAGATGCACCAGTTTGATCCGGAGTACTTCCCCAACCCTCGG GAATGGCACCACGAAAGACACCTGAGAGAGCAGGATGACGACGAGGGGCGAAGGACGGTAGTGGCCGACATGGGC ACGGTGAGGCCATACGGCGGAGGCCCGGCCATGTGTAAGGGACGAGCCTTTGCGCTGCGCGAGATGTTGCTGTAC TCGGCCATCATCATCTCTTTCTATGACATGCAGCCACCGAGCGGGCAGAGCTGGGAACACGCGCCCAAGACGTAC AAAACAGTGGCCACGAGGCATCCCAAAGCGCCAATCAAGGTGTGGATCAGGAGACGAGAGCAGCCGGTGGAAGGA CAAGAAAAGAGTGAGGATGCCGGCACGGCGTAG |
| Gene | >Hirsu2|4865 ATGGCGACACAGACTCTCCTGCCACTCGGCTCCGATTTCGGCTCCGAGTTTCTCACACCTTGGGTACCGCAGCCT GCCGTCCTCACCCTGCTGGCCACGATTGTCGTCATCCTTGCCACCGCAAAGCTCGTCCTGCCTGGATCGTCGACA CCCGGCGACGATGGCTGCAGATCGTGTCCGCCCAAGGTTCCCTTCTGGGTCCCCTTTTTCGGCCATGCGCCTCAG ATGTTCGCCAATTCGGACGGATTCCTGGCGAGACTGCGCGACCGCTATCCCCAGGGCGTCTTCTCCCTGCGGCTG TGCGGCAAGTTGCACCACTTCGTCCACGGACCGTCCATGGCCACCACGCTGCTCAACCGGCCCAAGACGGCGGCC GAGTCTGTCTCGAACAACCTGCTCGTCTCCAACTTCGGCTTCACCAAGAAAGACCAGGCCCATCACGCCACCATG GCGGCAGAGTCCAAGGCGAACTTCCAGTTCCTACTTTCCGAGCCCGGCCTCGGCGACCTTGTCCAGGAGACTGTG GCCCATGTCAAGCTGAACATTGCCGACCTCGTCACGTTCAATTCCAGTCCTGCCGACCAGATGGACTGGGAGTGG GAGGCTGGCGCCGAGGTCGTCAGCGGGCCCCGCGGTGATTCCTTCGTCCAGGCCGATCTCATGGAGCTGACCCGA AACTTCATCGCCAAGACGGCCAACTGTGCTCTTTACGGTACCGACTTCGTTCAGAACTTCGCCGACATCTGGCGG CTCATGTGGGCCTTTGACGACGCCTTCTTCCTGCTGGCCACGAGGATCCCCGGATGGGTGCCCTGGCCGCGGCTG CAGCGGGCCAAGGCTGCGCAGAGACGGATCCTCAGCTACACGCGCGAATTCAGCGAAGCCATGGACAAGCACATC CAAGGCCAGGACCCCGGCGCCAAGTGGCAGGACCTGGACAACGTCAGTGCCCTCGTCAAGGCCCGACACCAGACT TTCCGCAAGCACGGGCTGTCCATGGAGGCGCGGGCCAGCTGCGACCTGGCCCTGTGCTGGGCCATGAACGCAAAC GCCAACCAGCTCGTCCCTTGGATGCTGTTTGAGCTGTACCGGGATCCCGTGCTCCTCGAGCAGGTCCGGGAAGAG ATAGCTCCATACGTCCAGGTGAGGCAGCCCGAGAACGATTTCGGCATGGCCGTCTGGTTGCCGCCGGTCCTCGAA AAGATCGACCTCGAGGGCCTGATCAGCCGGTGCCCACTCCTCAAAGCGGCCTATATCGAGACGCTTCGGGTGTAC ACGGGCACCTGGACCATGAGGCGGCTCAATGAGGACGTGGTGCTCGGCGACCGAGGCAAGGCGGAACCGTATCTG CTGCGAAAGGGCACGTACGCCCATGTTTCCCAAGAGATGCACCAGTTTGATCCGGAGTACTTCCCCAACCCTCGG GAATGGCACCACGAAAGACACCTGAGAGAGCAGGATGACGACGAGGGGCGAAGGACGGTAGTGGCCGACATGGGC ACGGTGAGGCCATACGGTAAGCACCCTCCCTCTTCTTTCTCCTCGAGCCGTTGCCAGTCCACCTTGGTCCAGTTC AACGCGCTGACGCCTTTTTTGTTGCCATCCGATTAGGCGGAGGCCCGGCCATGTGTAAGGGACGAGCCTTTGCGC TGCGCGAGATGTTGCTGTACTCGGCCATCATCATCTCTTTCTATGACATGCAGCCACCGAGCGGGCAGAGCTGGG AACACGCGCCCAAGACGTACAAAACAGTGGCCACGAGGCATCCCAAAGCGCCAATCAAGGTGTGGATCAGGAGAC GAGAGCAGCCGGTGGAAGGACAAGAAAAGAGTGAGGATGCCGGCACGGCGTAG |