Fungal Genomics

at Utrecht University

General Properties

Protein ID	Hirsu2\|442
Gene name
Location	Contig_109:2890..6461
Strand	-
Gene length (bp)	3571
Transcript length (bp)	3507
Coding sequence length (bp)	3507
Protein length (aa)	1169

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF05277	DUF726	Protein of unknown function (DUF726)	1.3E-126	585	922

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|O14244\|YELD_SCHPO	Uncharacterized membrane protein C6F6.13c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC6F6.13c PE=3 SV=1	198	951	0.0E+00
sp\|P43564\|YFD4_YEAST	Uncharacterized membrane protein YFL034W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFL034W PE=1 SV=2	246	962	0.0E+00
sp\|Q5TGY1\|TMCO4_HUMAN	Transmembrane and coiled-coil domain-containing protein 4 OS=Homo sapiens GN=TMCO4 PE=2 SV=1	515	920	9.0E-51
sp\|Q20035\|TMCO4_CAEEL	Uncharacterized membrane protein F35D11.3 OS=Caenorhabditis elegans GN=F35D11.3 PE=3 SV=2	513	934	1.0E-50
sp\|Q499U8\|TMCO4_RAT	Transmembrane and coiled-coil domain-containing protein 4 OS=Rattus norvegicus GN=Tmco4 PE=2 SV=1	515	920	2.0E-49

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|O14244\|YELD_SCHPO	Uncharacterized membrane protein C6F6.13c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC6F6.13c PE=3 SV=1	198	951	0.0E+00
sp\|P43564\|YFD4_YEAST	Uncharacterized membrane protein YFL034W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFL034W PE=1 SV=2	246	962	0.0E+00
sp\|Q5TGY1\|TMCO4_HUMAN	Transmembrane and coiled-coil domain-containing protein 4 OS=Homo sapiens GN=TMCO4 PE=2 SV=1	515	920	9.0E-51
sp\|Q20035\|TMCO4_CAEEL	Uncharacterized membrane protein F35D11.3 OS=Caenorhabditis elegans GN=F35D11.3 PE=3 SV=2	513	934	1.0E-50
sp\|Q499U8\|TMCO4_RAT	Transmembrane and coiled-coil domain-containing protein 4 OS=Rattus norvegicus GN=Tmco4 PE=2 SV=1	515	920	2.0E-49
sp\|Q91WU4\|TMCO4_MOUSE	Transmembrane and coiled-coil domain-containing protein 4 OS=Mus musculus GN=Tmco4 PE=2 SV=2	515	916	3.0E-48
sp\|Q9US10\|YK68_SCHPO	Uncharacterized membrane protein C6F6.13c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC607.08c PE=3 SV=1	526	944	1.0E-42

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GO

(None)

SignalP

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SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 29	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	596	618	22
2	631	653	22

Transcription Factor Class

(None)

Expression data

No expression data available for this genome

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Hirsu2\|442 MDNKKEPEPDGNASRGHQASSVPAPAAAAQPDADEFGLPIRRYASPGPATAASPPSAAEGGAAAEGDDGVSREET QVTGDRTPTSLPAPPSGKRSDPDSDSDDGAFEDAQPALPRVLTAPSTPRIGSTPEATGAGQPGSSVDGEAAPASS DNAESEARAADAKTSQTSPQPQEATRRQVDGAAHTPRPDEAPRPPSPSKASADEPNNRHAQHAGAAAGPHNGLGI SEFSHQQVSMQPEEKGDDDDGGWQTMPSFARYDMYDDDDRLIAREHNETEESDEKYGYGGLGGAGKGYTRVIMDE DAESATSMDENTQYLFKEGNGTSMAGEDEGRDAVAQMQATKDLLTEGQRIAYVGVVRLEIAGLVNDAEKVEMTKK TKKDVQTAAEAVRMWGQKMMIRLYSHMDISEAEQLMIEQLAAHGVMPGDLTPALHANSRVHNPMAAEHDAADSLK ISSSSSSLASSASSPPPSVVEERAAEPPPPYEAAEGAEVPEAQMPSQMPTTEKIDIDLRWTVLCDLFLILIADSV YDARSRVLLERVGASLDITWIDICRFEKRITDALEMQQAAEKENWNEDEHMEVRRKMAQKRRFVMMGLATVGGGL VIGLSAGLLAPVIGAGLAAGFTTIGVTGTSSFLAGAGGAAIITSGAAASGSIIGVRAANRRTGAVKTFEYRPLHN KKRVNLIVTVSGWLTGKVDDVRLPFSTVDPIMGDMYSVLWEPEMLRSMGDTINILATEALTQGLQQILGSTILVS LMAALQLPIVLTKLSYLIDNPWAVSLDRATAAGLILADSLLERSLGTRPITLVGYSLGARVIFSCLQELAKKGAY GLIQNVYLFGSPIVVKKEEYLRARTVVCGRFLNGYNRNDWILGYLFRLTNGGIRRVAGLGPIEELPWIENMDVTD LVPGHMEYRKSMPKLLIKCGWEVESEEFTEIEDPDPENHQERQRELINEIEEARKELEREGKAKKSTKFGIFGRR KKAERQEWEVYEDTAGKQTSKTGEKEGISNPGVLFDVDAIRAELAKETAQDGAPEEGLQVREIESTLPPMRLDIS PVSPSALSPGGDRRNPLRETKSAELVPGRRIGEGWGQHGATPGPVGGGVAGEEEGEVQMTFDLSFDEPRYKESKS EDGLARPAVKASQTVPNLALQDPWADADDEDFGKEKEISMTFA*
Coding	>Hirsu2\|442 ATGGACAACAAGAAAGAACCAGAGCCCGACGGCAACGCCTCCCGAGGCCACCAGGCGTCGTCAGTGCCGGCGCCA GCAGCGGCGGCCCAGCCGGATGCCGACGAGTTCGGCCTGCCCATCCGTCGCTATGCCAGCCCCGGGCCGGCCACC GCTGCCAGCCCGCCTAGTGCGGCCGAGGGCGGTGCCGCGGCCGAGGGAGACGATGGCGTCTCGAGGGAGGAGACG CAGGTGACCGGAGACAGGACTCCCACCTCGCTGCCGGCACCGCCATCGGGCAAGAGAAGCGATCCCGACAGCGAC AGCGACGATGGCGCCTTCGAAGACGCCCAGCCCGCTCTTCCCCGAGTCCTCACCGCGCCCTCGACGCCACGGATA GGTTCGACGCCAGAAGCAACCGGCGCAGGTCAGCCGGGCTCCAGCGTCGATGGCGAGGCCGCGCCCGCCTCGTCG GACAATGCCGAATCCGAGGCACGTGCGGCGGATGCAAAGACCTCGCAGACCAGCCCACAGCCGCAAGAGGCCACC CGCCGCCAAGTCGACGGCGCTGCCCACACGCCACGCCCCGACGAAGCACCCCGTCCTCCGAGCCCGTCCAAGGCG AGCGCCGACGAGCCCAACAACAGGCACGCTCAGCATGCGGGTGCCGCGGCCGGTCCCCACAATGGCCTCGGTATT TCCGAGTTCTCTCACCAGCAAGTGTCGATGCAGCCGGAGGAGAAGGGCGACGACGACGACGGGGGCTGGCAGACC ATGCCTTCCTTCGCGAGATACGACATGTACGACGACGACGATCGCCTGATTGCTCGGGAGCACAACGAGACCGAA GAGAGCGACGAAAAGTACGGCTATGGCGGGCTCGGCGGGGCAGGAAAGGGCTACACTCGGGTCATCATGGACGAA GACGCCGAGTCGGCCACGAGCATGGACGAAAACACACAGTATCTCTTCAAGGAAGGGAACGGCACAAGCATGGCG GGCGAGGACGAGGGCCGGGACGCCGTGGCTCAGATGCAGGCCACCAAGGATCTGCTCACCGAGGGTCAGAGGATC GCCTACGTCGGCGTCGTTCGCCTCGAGATCGCCGGGCTGGTCAACGACGCCGAGAAGGTGGAGATGACCAAGAAG ACCAAGAAGGACGTCCAGACCGCGGCTGAGGCCGTCAGGATGTGGGGCCAGAAGATGATGATCCGCCTCTACTCG CACATGGACATAAGCGAGGCGGAGCAGCTCATGATCGAGCAACTGGCGGCGCATGGCGTGATGCCGGGCGACTTG ACCCCGGCCCTCCACGCCAACTCGCGAGTGCACAACCCCATGGCGGCGGAGCACGACGCGGCCGACAGCCTGAAG ATCTCGTCTTCGTCCTCGTCGCTGGCGTCGTCGGCGTCGTCGCCGCCGCCGAGCGTGGTGGAGGAGAGGGCCGCG GAGCCGCCCCCGCCATACGAAGCCGCCGAGGGCGCCGAGGTCCCCGAGGCGCAGATGCCGTCGCAGATGCCGACG ACGGAGAAGATCGATATCGACCTCCGCTGGACCGTCCTCTGCGACCTGTTCCTGATCCTGATCGCCGACTCCGTC TACGACGCGCGCTCGCGAGTGCTCCTGGAGCGTGTCGGCGCCAGTCTCGACATTACGTGGATCGACATATGCAGG TTCGAGAAGAGGATAACGGACGCCTTGGAGATGCAGCAGGCGGCGGAGAAGGAGAACTGGAACGAGGACGAACAC ATGGAGGTCCGCAGGAAGATGGCGCAGAAGAGGAGATTTGTCATGATGGGCCTCGCCACGGTGGGCGGCGGCCTC GTCATCGGCCTCTCGGCCGGCCTCCTGGCCCCCGTCATCGGCGCCGGTCTGGCCGCCGGCTTCACGACGATTGGG GTGACGGGGACGAGCAGCTTCCTCGCCGGCGCGGGCGGCGCCGCCATCATCACGTCGGGAGCCGCCGCCTCGGGC AGCATCATCGGCGTCAGGGCGGCCAACCGCCGCACCGGCGCGGTCAAGACGTTCGAGTACCGCCCGCTGCACAAC AAGAAGCGGGTCAACCTGATCGTGACGGTTTCGGGCTGGCTGACGGGAAAGGTGGACGACGTCCGCCTCCCGTTC AGCACCGTGGACCCCATCATGGGAGACATGTATTCGGTCCTGTGGGAGCCGGAGATGCTCCGGAGCATGGGCGAC ACCATCAACATCCTGGCCACCGAGGCTCTCACGCAAGGCCTGCAGCAGATACTGGGCAGCACCATCCTCGTCAGT CTCATGGCGGCCCTCCAGCTGCCCATCGTCCTGACCAAGTTATCCTACCTCATCGACAACCCCTGGGCTGTATCC CTCGATCGGGCGACGGCGGCCGGCCTCATCTTGGCCGATTCCCTGCTGGAGCGCAGCCTGGGCACGCGCCCCATA ACCCTGGTCGGGTACTCGCTCGGTGCGCGCGTCATCTTCTCGTGCCTGCAGGAGCTGGCCAAGAAGGGCGCCTAT GGCCTGATCCAGAACGTCTACCTGTTCGGCTCGCCGATCGTGGTGAAGAAGGAAGAGTATCTCCGGGCCAGGACA GTGGTCTGCGGCCGCTTCCTGAACGGCTACAACCGCAACGACTGGATCCTCGGCTACCTGTTCCGGCTGACCAAC GGCGGCATCCGGCGGGTGGCGGGGCTCGGTCCCATCGAAGAGTTGCCCTGGATCGAGAACATGGACGTGACGGAC CTGGTGCCCGGCCACATGGAATATCGAAAGTCGATGCCGAAGCTCCTGATCAAGTGCGGCTGGGAGGTGGAGAGC GAGGAGTTTACAGAGATCGAAGACCCGGACCCCGAAAATCACCAGGAGCGGCAGAGGGAGCTCATCAACGAGATC GAGGAGGCTCGCAAGGAGCTGGAGAGAGAGGGCAAGGCCAAGAAGAGCACCAAGTTTGGCATCTTTGGCCGCCGC AAGAAGGCCGAGAGACAGGAGTGGGAGGTCTACGAGGACACGGCGGGCAAGCAAACGAGCAAGACGGGAGAGAAG GAGGGGATCAGCAACCCGGGGGTCCTCTTCGACGTGGATGCCATCCGGGCGGAGCTGGCCAAAGAGACGGCGCAA GACGGCGCGCCGGAGGAAGGGCTGCAGGTGAGGGAGATAGAGTCGACGCTACCGCCCATGAGGCTCGACATCTCG CCCGTCTCTCCGTCGGCACTGTCGCCGGGAGGCGACAGGCGAAATCCGCTGCGGGAGACGAAGAGCGCCGAGTTG GTGCCTGGCCGGCGAATCGGCGAAGGGTGGGGGCAACACGGTGCCACCCCCGGACCAGTCGGCGGAGGCGTGGCG GGAGAAGAAGAGGGGGAGGTGCAGATGACGTTCGACCTGTCTTTCGACGAGCCGCGGTACAAGGAGTCGAAGAGC GAGGACGGACTGGCTCGGCCGGCCGTGAAGGCCTCACAGACGGTGCCGAATCTGGCCCTGCAGGACCCGTGGGCT GACGCGGACGACGAAGACTTCGGAAAGGAGAAGGAGATATCGATGACGTTCGCTTAG
Transcript	>Hirsu2\|442 ATGGACAACAAGAAAGAACCAGAGCCCGACGGCAACGCCTCCCGAGGCCACCAGGCGTCGTCAGTGCCGGCGCCA GCAGCGGCGGCCCAGCCGGATGCCGACGAGTTCGGCCTGCCCATCCGTCGCTATGCCAGCCCCGGGCCGGCCACC GCTGCCAGCCCGCCTAGTGCGGCCGAGGGCGGTGCCGCGGCCGAGGGAGACGATGGCGTCTCGAGGGAGGAGACG CAGGTGACCGGAGACAGGACTCCCACCTCGCTGCCGGCACCGCCATCGGGCAAGAGAAGCGATCCCGACAGCGAC AGCGACGATGGCGCCTTCGAAGACGCCCAGCCCGCTCTTCCCCGAGTCCTCACCGCGCCCTCGACGCCACGGATA GGTTCGACGCCAGAAGCAACCGGCGCAGGTCAGCCGGGCTCCAGCGTCGATGGCGAGGCCGCGCCCGCCTCGTCG GACAATGCCGAATCCGAGGCACGTGCGGCGGATGCAAAGACCTCGCAGACCAGCCCACAGCCGCAAGAGGCCACC CGCCGCCAAGTCGACGGCGCTGCCCACACGCCACGCCCCGACGAAGCACCCCGTCCTCCGAGCCCGTCCAAGGCG AGCGCCGACGAGCCCAACAACAGGCACGCTCAGCATGCGGGTGCCGCGGCCGGTCCCCACAATGGCCTCGGTATT TCCGAGTTCTCTCACCAGCAAGTGTCGATGCAGCCGGAGGAGAAGGGCGACGACGACGACGGGGGCTGGCAGACC ATGCCTTCCTTCGCGAGATACGACATGTACGACGACGACGATCGCCTGATTGCTCGGGAGCACAACGAGACCGAA GAGAGCGACGAAAAGTACGGCTATGGCGGGCTCGGCGGGGCAGGAAAGGGCTACACTCGGGTCATCATGGACGAA GACGCCGAGTCGGCCACGAGCATGGACGAAAACACACAGTATCTCTTCAAGGAAGGGAACGGCACAAGCATGGCG GGCGAGGACGAGGGCCGGGACGCCGTGGCTCAGATGCAGGCCACCAAGGATCTGCTCACCGAGGGTCAGAGGATC GCCTACGTCGGCGTCGTTCGCCTCGAGATCGCCGGGCTGGTCAACGACGCCGAGAAGGTGGAGATGACCAAGAAG ACCAAGAAGGACGTCCAGACCGCGGCTGAGGCCGTCAGGATGTGGGGCCAGAAGATGATGATCCGCCTCTACTCG CACATGGACATAAGCGAGGCGGAGCAGCTCATGATCGAGCAACTGGCGGCGCATGGCGTGATGCCGGGCGACTTG ACCCCGGCCCTCCACGCCAACTCGCGAGTGCACAACCCCATGGCGGCGGAGCACGACGCGGCCGACAGCCTGAAG ATCTCGTCTTCGTCCTCGTCGCTGGCGTCGTCGGCGTCGTCGCCGCCGCCGAGCGTGGTGGAGGAGAGGGCCGCG GAGCCGCCCCCGCCATACGAAGCCGCCGAGGGCGCCGAGGTCCCCGAGGCGCAGATGCCGTCGCAGATGCCGACG ACGGAGAAGATCGATATCGACCTCCGCTGGACCGTCCTCTGCGACCTGTTCCTGATCCTGATCGCCGACTCCGTC TACGACGCGCGCTCGCGAGTGCTCCTGGAGCGTGTCGGCGCCAGTCTCGACATTACGTGGATCGACATATGCAGG TTCGAGAAGAGGATAACGGACGCCTTGGAGATGCAGCAGGCGGCGGAGAAGGAGAACTGGAACGAGGACGAACAC ATGGAGGTCCGCAGGAAGATGGCGCAGAAGAGGAGATTTGTCATGATGGGCCTCGCCACGGTGGGCGGCGGCCTC GTCATCGGCCTCTCGGCCGGCCTCCTGGCCCCCGTCATCGGCGCCGGTCTGGCCGCCGGCTTCACGACGATTGGG GTGACGGGGACGAGCAGCTTCCTCGCCGGCGCGGGCGGCGCCGCCATCATCACGTCGGGAGCCGCCGCCTCGGGC AGCATCATCGGCGTCAGGGCGGCCAACCGCCGCACCGGCGCGGTCAAGACGTTCGAGTACCGCCCGCTGCACAAC AAGAAGCGGGTCAACCTGATCGTGACGGTTTCGGGCTGGCTGACGGGAAAGGTGGACGACGTCCGCCTCCCGTTC AGCACCGTGGACCCCATCATGGGAGACATGTATTCGGTCCTGTGGGAGCCGGAGATGCTCCGGAGCATGGGCGAC ACCATCAACATCCTGGCCACCGAGGCTCTCACGCAAGGCCTGCAGCAGATACTGGGCAGCACCATCCTCGTCAGT CTCATGGCGGCCCTCCAGCTGCCCATCGTCCTGACCAAGTTATCCTACCTCATCGACAACCCCTGGGCTGTATCC CTCGATCGGGCGACGGCGGCCGGCCTCATCTTGGCCGATTCCCTGCTGGAGCGCAGCCTGGGCACGCGCCCCATA ACCCTGGTCGGGTACTCGCTCGGTGCGCGCGTCATCTTCTCGTGCCTGCAGGAGCTGGCCAAGAAGGGCGCCTAT GGCCTGATCCAGAACGTCTACCTGTTCGGCTCGCCGATCGTGGTGAAGAAGGAAGAGTATCTCCGGGCCAGGACA GTGGTCTGCGGCCGCTTCCTGAACGGCTACAACCGCAACGACTGGATCCTCGGCTACCTGTTCCGGCTGACCAAC GGCGGCATCCGGCGGGTGGCGGGGCTCGGTCCCATCGAAGAGTTGCCCTGGATCGAGAACATGGACGTGACGGAC CTGGTGCCCGGCCACATGGAATATCGAAAGTCGATGCCGAAGCTCCTGATCAAGTGCGGCTGGGAGGTGGAGAGC GAGGAGTTTACAGAGATCGAAGACCCGGACCCCGAAAATCACCAGGAGCGGCAGAGGGAGCTCATCAACGAGATC GAGGAGGCTCGCAAGGAGCTGGAGAGAGAGGGCAAGGCCAAGAAGAGCACCAAGTTTGGCATCTTTGGCCGCCGC AAGAAGGCCGAGAGACAGGAGTGGGAGGTCTACGAGGACACGGCGGGCAAGCAAACGAGCAAGACGGGAGAGAAG GAGGGGATCAGCAACCCGGGGGTCCTCTTCGACGTGGATGCCATCCGGGCGGAGCTGGCCAAAGAGACGGCGCAA GACGGCGCGCCGGAGGAAGGGCTGCAGGTGAGGGAGATAGAGTCGACGCTACCGCCCATGAGGCTCGACATCTCG CCCGTCTCTCCGTCGGCACTGTCGCCGGGAGGCGACAGGCGAAATCCGCTGCGGGAGACGAAGAGCGCCGAGTTG GTGCCTGGCCGGCGAATCGGCGAAGGGTGGGGGCAACACGGTGCCACCCCCGGACCAGTCGGCGGAGGCGTGGCG GGAGAAGAAGAGGGGGAGGTGCAGATGACGTTCGACCTGTCTTTCGACGAGCCGCGGTACAAGGAGTCGAAGAGC GAGGACGGACTGGCTCGGCCGGCCGTGAAGGCCTCACAGACGGTGCCGAATCTGGCCCTGCAGGACCCGTGGGCT GACGCGGACGACGAAGACTTCGGAAAGGAGAAGGAGATATCGATGACGTTCGCTTAG
Gene	>Hirsu2\|442 ATGGACAACAAGAAAGAACCAGAGCCCGACGGCAACGCCTCCCGAGGCCACCAGGCGTCGTCAGTGCCGGCGCCA GCAGCGGCGGCCCAGCCGGATGCCGACGAGTTCGGCCTGCCCATCCGTCGCTATGCCAGCCCCGGGCCGGCCACC GCTGCCAGCCCGCCTAGTGCGGCCGAGGGCGGTGCCGCGGCCGAGGGAGACGATGGCGTCTCGAGGGAGGAGACG CAGGTGACCGGAGACAGGACTCCCACCTCGCTGCCGGCACCGCCATCGGGCAAGAGAAGCGATCCCGACAGCGAC AGCGACGATGGCGCCTTCGAAGACGCCCAGCCCGCTCTTCCCCGAGTCCTCACCGCGCCCTCGACGCCACGGATA GGTTCGACGCCAGAAGCAACCGGCGCAGGTCAGCCGGGCTCCAGCGTCGATGGCGAGGCCGCGCCCGCCTCGTCG GACAATGCCGAATCCGAGGCACGTGCGGCGGATGCAAAGACCTCGCAGACCAGCCCACAGCCGCAAGAGGCCACC CGCCGCCAAGTCGACGGCGCTGCCCACACGCCACGCCCCGACGAAGCACCCCGTCCTCCGAGCCCGTCCAAGGCG AGCGCCGACGAGCCCAACAACAGGCACGCTCAGCATGCGGGTGCCGCGGCCGGTCCCCACAATGGCCTCGGTATT TCCGAGTTCTCTCACCAGCAAGTGTCGATGCAGCCGGAGGAGAAGGGCGACGACGACGACGGGGGCTGGCAGACC ATGCCTTCCTTCGCGAGATACGACATGTACGACGACGACGATCGCCTGATTGCTCGGGAGCACAACGAGACCGAA GAGAGCGACGAAAAGTACGGCTATGGCGGGCTCGGCGGGGCAGGAAAGGGCTACACTCGGGTCATCATGGACGAA GACGCCGAGTCGGCCACGAGCATGGACGAAAACACACAGTATCTCTTCAAGGAAGGGAACGGCACAAGCATGGCG GGCGAGGACGAGGGCCGGGACGCCGTGGCTCAGATGCAGGCCACCAAGGATCTGCTCACCGAGGGTCAGAGGATC GCCTACGTCGGCGTCGTTCGCCTCGAGATCGCCGGGCTGGTCAACGACGCCGAGAAGGTGGAGATGACCAAGAAG ACCAAGAAGGACGTCCAGACCGCGGCTGAGGCCGTCAGGATGTGGGGCCAGAAGATGATGATCCGCCTCTACTCG CACATGGACATAAGCGAGGCGGAGCAGCTCATGATCGAGCAACTGGCGGCGCATGGCGTGATGCCGGGCGACTTG ACCCCGGCCCTCCACGCCAACTCGCGAGTGCACAACCCCATGGCGGCGGAGCACGACGCGGCCGACAGCCTGAAG ATCTCGTCTTCGTCCTCGTCGCTGGCGTCGTCGGCGTCGTCGCCGCCGCCGAGCGTGGTGGAGGAGAGGGCCGCG GAGCCGCCCCCGCCATACGAAGCCGCCGAGGGCGCCGAGGTCCCCGAGGCGCAGATGCCGTCGCAGATGCCGACG ACGGAGAAGATCGATATCGACCTCCGCTGGACCGTCCTCTGCGACCTGTTCCTGATCCTGATCGCCGACTCCGTC TACGACGCGCGCTCGCGAGTGCTCCTGGAGCGTGTCGGCGCCAGTCTCGACATTACGTGGATCGACATATGCAGG TTCGAGAAGAGGATAACGGACGCCTTGGAGATGCAGCAGGCGGCGGAGAAGGAGAACTGGAACGAGGACGAACAC ATGGAGGTCCGCAGGAAGATGGCGCAGAAGAGGAGATTTGTCATGATGGGCCTCGCCACGGTGGGCGGCGGCCTC GTCATCGGCCTCTCGGCCGGCCTCCTGGCCCCCGTCATCGGCGCCGGTCTGGCCGCCGGCTTCACGACGATTGGG GTGACGGGGACGAGCAGCTTCCTCGCCGGCGCGGGCGGCGCCGCCATCATCACGTCGGGAGCCGCCGCCTCGGGC AGCATCATCGGCGTCAGGGCGGCCAACCGCCGCACCGGCGCGGTCAAGACGTTCGAGTACCGCCCGCTGCACAAC AAGAAGCGGGTCAACCTGATCGTGACGGTTTCGGGCTGGCTGACGGGAAAGGTGGACGACGTCCGCCTCCCGTTC AGCACCGTGGACCCCATCATGGGAGACATGTATTCGGTCCTGTGGGAGCCGGAGATGCTCCGGAGCATGGGCGAC ACCATCAACATCCTGGCCACCGAGGTAGAGTTGTCACCCGCCCGCCACGTGCCCGGGGCCCGTCCGTAATGCTGA CCCGACGACGCAGGCTCTCACGCAAGGCCTGCAGCAGATACTGGGCAGCACCATCCTCGTCAGTCTCATGGCGGC CCTCCAGCTGCCCATCGTCCTGACCAAGTTATCCTACCTCATCGACAACCCCTGGGCTGTATCCCTCGATCGGGC GACGGCGGCCGGCCTCATCTTGGCCGATTCCCTGCTGGAGCGCAGCCTGGGCACGCGCCCCATAACCCTGGTCGG GTACTCGCTCGGTGCGCGCGTCATCTTCTCGTGCCTGCAGGAGCTGGCCAAGAAGGGCGCCTATGGCCTGATCCA GAACGTCTACCTGTTCGGCTCGCCGATCGTGGTGAAGAAGGAAGAGTATCTCCGGGCCAGGACAGTGGTCTGCGG CCGCTTCCTGAACGGCTACAACCGCAACGACTGGATCCTCGGCTACCTGTTCCGGCTGACCAACGGCGGCATCCG GCGGGTGGCGGGGCTCGGTCCCATCGAAGAGTTGCCCTGGATCGAGAACATGGACGTGACGGACCTGGTGCCCGG CCACATGGAATATCGAAAGTCGATGCCGAAGCTCCTGATCAAGTGCGGCTGGGAGGTGGAGAGCGAGGAGTTTAC AGAGATCGAAGACCCGGACCCCGAAAATCACCAGGAGCGGCAGAGGGAGCTCATCAACGAGATCGAGGAGGCTCG CAAGGAGCTGGAGAGAGAGGGCAAGGCCAAGAAGAGCACCAAGTTTGGCATCTTTGGCCGCCGCAAGAAGGCCGA GAGACAGGAGTGGGAGGTCTACGAGGACACGGCGGGCAAGCAAACGAGCAAGACGGGAGAGAAGGAGGGGATCAG CAACCCGGGGGTCCTCTTCGACGTGGATGCCATCCGGGCGGAGCTGGCCAAAGAGACGGCGCAAGACGGCGCGCC GGAGGAAGGGCTGCAGGTGAGGGAGATAGAGTCGACGCTACCGCCCATGAGGCTCGACATCTCGCCCGTCTCTCC GTCGGCACTGTCGCCGGGAGGCGACAGGCGAAATCCGCTGCGGGAGACGAAGAGCGCCGAGTTGGTGCCTGGCCG GCGAATCGGCGAAGGGTGGGGGCAACACGGTGCCACCCCCGGACCAGTCGGCGGAGGCGTGGCGGGAGAAGAAGA GGGGGAGGTGCAGATGACGTTCGACCTGTCTTTCGACGAGCCGCGGTACAAGGAGTCGAAGAGCGAGGACGGACT GGCTCGGCCGGCCGTGAAGGCCTCACAGACGGTGCCGAATCTGGCCCTGCAGGACCCGTGGGCTGACGCGGACGA CGAAGACTTCGGAAAGGAGAAGGAGATATCGATGACGTTCGCTTAG

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