© 2023 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|3550 |
| Gene name | |
| Location | Contig_1936:1875..3646 |
| Strand | - |
| Gene length (bp) | 1771 |
| Transcript length (bp) | 1464 |
| Coding sequence length (bp) | 1464 |
| Protein length (aa) | 488 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF12349 | Sterol-sensing | Sterol-sensing domain of SREBP cleavage-activation | 5.2E-38 | 294 | 439 |
| PF02460 | Patched | Patched family | 1.9E-10 | 280 | 427 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|A6QM06|SCAP_BOVIN | Sterol regulatory element-binding protein cleavage-activating protein OS=Bos taurus GN=SCAP PE=2 SV=1 | 161 | 436 | 3.0E-22 |
| sp|Q5MNU5|SCAP_PIG | Sterol regulatory element-binding protein cleavage-activating protein OS=Sus scrofa GN=SCAP PE=2 SV=2 | 161 | 436 | 4.0E-22 |
| sp|Q12770|SCAP_HUMAN | Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP PE=1 SV=4 | 161 | 436 | 5.0E-21 |
| sp|Q6GQT6|SCAP_MOUSE | Sterol regulatory element-binding protein cleavage-activating protein OS=Mus musculus GN=Scap PE=1 SV=1 | 172 | 436 | 2.0E-19 |
| sp|A2RRU4|SCAP_RAT | Sterol regulatory element-binding protein cleavage-activating protein OS=Rattus norvegicus GN=Scap PE=2 SV=1 | 172 | 436 | 2.0E-19 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|A6QM06|SCAP_BOVIN | Sterol regulatory element-binding protein cleavage-activating protein OS=Bos taurus GN=SCAP PE=2 SV=1 | 161 | 436 | 3.0E-22 |
| sp|Q5MNU5|SCAP_PIG | Sterol regulatory element-binding protein cleavage-activating protein OS=Sus scrofa GN=SCAP PE=2 SV=2 | 161 | 436 | 4.0E-22 |
| sp|Q12770|SCAP_HUMAN | Sterol regulatory element-binding protein cleavage-activating protein OS=Homo sapiens GN=SCAP PE=1 SV=4 | 161 | 436 | 5.0E-21 |
| sp|Q6GQT6|SCAP_MOUSE | Sterol regulatory element-binding protein cleavage-activating protein OS=Mus musculus GN=Scap PE=1 SV=1 | 172 | 436 | 2.0E-19 |
| sp|A2RRU4|SCAP_RAT | Sterol regulatory element-binding protein cleavage-activating protein OS=Rattus norvegicus GN=Scap PE=2 SV=1 | 172 | 436 | 2.0E-19 |
| sp|A0JPH4|SCAP_XENLA | Sterol regulatory element-binding protein cleavage-activating protein OS=Xenopus laevis GN=scap PE=2 SV=1 | 39 | 453 | 4.0E-19 |
| sp|P97260|SCAP_CRIGR | Sterol regulatory element-binding protein cleavage-activating protein OS=Cricetulus griseus GN=SCAP PE=1 SV=1 | 161 | 436 | 8.0E-19 |
| sp|O43043|SCAP_SCHPO | Sterol regulatory element-binding protein cleavage-activating protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=scp1 PE=1 SV=1 | 273 | 462 | 2.0E-18 |
| sp|O15118|NPC1_HUMAN | Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2 | 219 | 433 | 1.0E-10 |
| sp|P56941|NPC1_PIG | Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1 | 219 | 433 | 2.0E-10 |
| sp|O35604|NPC1_MOUSE | Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=2 | 255 | 433 | 3.0E-09 |
| sp|Q6T3U3|NPCL1_RAT | Niemann-Pick C1-like protein 1 OS=Rattus norvegicus GN=Npc1l1 PE=1 SV=1 | 255 | 447 | 5.0E-08 |
| sp|Q13635|PTC1_HUMAN | Protein patched homolog 1 OS=Homo sapiens GN=PTCH1 PE=1 SV=2 | 266 | 433 | 5.0E-07 |
| sp|Q61115|PTC1_MOUSE | Protein patched homolog 1 OS=Mus musculus GN=Ptch1 PE=1 SV=1 | 266 | 433 | 6.0E-07 |
| sp|Q90693|PTC1_CHICK | Protein patched homolog 1 OS=Gallus gallus GN=PTCH1 PE=1 SV=1 | 266 | 433 | 7.0E-07 |
| sp|Q0EEE2|PTHD3_MOUSE | Patched domain-containing protein 3 OS=Mus musculus GN=Ptchd3 PE=1 SV=1 | 259 | 431 | 7.0E-07 |
| sp|Q12200|NPC1_YEAST | Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NCR1 PE=1 SV=1 | 219 | 431 | 1.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0016021 | integral component of membrane | Yes |
| GO:0005575 | cellular_component | No |
| GO:0110165 | cellular anatomical entity | No |
| GO:0031224 | intrinsic component of membrane | No |
| Localizations | Signals | Cytoplasm | Nucleus | Extracellular | Cell membrane | Mitochondrion | Plastid | Endoplasmic reticulum | Lysosome vacuole | Golgi apparatus | Peroxisome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Endoplasmic reticulum|Golgi apparatus | Signal peptide|Transmembrane domain | 0.0731 | 0.1886 | 0.0447 | 0.4776 | 0.1515 | 0.161 | 0.7513 | 0.3932 | 0.7189 | 0.1881 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 39 | 61 | 22 |
| 2 | 270 | 287 | 17 |
| 3 | 302 | 324 | 22 |
| 4 | 336 | 358 | 22 |
| 5 | 373 | 395 | 22 |
| 6 | 402 | 424 | 22 |
| 7 | 469 | 486 | 17 |
| Orthofinder run ID | 4 |
| Orthogroup | 2469 |
| Change Orthofinder run |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|3550 MIWYLLYPLRGTTEAPTLPTSHPLYGVFARYGRYATRHVVATLLVSAAVATILIYPIPFLFTSDYINGASNLPKH VWTVAQPLPYDNTVEPDIIMRSMWVHASYMQALNAELLVSALELQDDLLGITKNFSPARSRRAPLTDDLLEQGMS LSQRDAIHVANGLTPNSWFFHSPLLYWSCSRDRILADDDILSTVNDKKNQSTSANVTLRHSIVFSGKRFEDRRLL AADALVITLLHLRDSPVGRGWERRALELPEKLYEFQFRPISMQDIASLAVAYGLTLLYFLNSLSKLRAVKSKVGL IVTIMVQIILSVMSSFTVCAIFKIDLSRIPRAAYPLVVLAMSLEHIFRLINAVILIPFEDSVSHRIGKAFGETAP IALASTLQNVLMLAGLSRLVSPGVSGFCVFAAIAIVFDFFYLSTFFLSVLSVDVRRMELVDALAKASMRRNPSDP GVRGSRRSWWDPVFHGKIAMSTRIAGTIVMFGFVLLT* |
| Coding | >Hirsu2|3550 ATGATCTGGTATCTGCTGTACCCGCTTCGAGGAACAACGGAGGCTCCCACCCTCCCTACTTCGCATCCTCTGTAC GGCGTATTTGCTCGCTATGGCCGCTATGCCACACGTCATGTCGTCGCCACATTGCTGGTCTCGGCCGCCGTGGCC ACCATCCTAATCTACCCTATCCCGTTTCTCTTTACTAGCGACTACATCAACGGCGCCTCAAACTTGCCCAAACAT GTCTGGACCGTCGCCCAGCCTCTGCCGTATGACAACACTGTCGAGCCAGACATAATCATGCGCTCCATGTGGGTG CACGCTAGCTACATGCAGGCCTTGAACGCTGAACTCCTCGTCTCAGCTCTCGAGCTCCAGGACGACCTGCTTGGC ATCACGAAGAACTTCAGCCCCGCCCGTTCTCGCCGCGCACCCCTGACGGATGACTTGCTTGAACAAGGCATGTCG CTGTCCCAACGAGACGCCATACATGTCGCCAACGGGCTGACCCCAAACTCGTGGTTTTTCCACTCACCCTTACTG TATTGGAGCTGCTCGCGCGACCGCATTTTGGCCGACGATGACATCCTCTCCACCGTCAATGACAAGAAGAACCAG TCCACATCCGCCAATGTCACTTTACGTCACTCGATTGTCTTCAGCGGCAAGCGCTTCGAGGACCGCCGTCTGCTG GCCGCCGACGCCCTTGTCATCACACTACTCCACCTTCGCGATTCCCCTGTGGGACGTGGGTGGGAGAGAAGAGCA CTGGAGCTTCCAGAAAAGCTCTACGAGTTTCAGTTCCGACCAATCTCAATGCAGGACATTGCCAGTCTCGCCGTC GCATATGGCCTGACGCTGCTCTATTTTCTCAACAGTCTCTCAAAGCTCCGGGCCGTCAAGTCTAAAGTCGGCCTC ATTGTCACCATCATGGTGCAGATAATTTTATCGGTCATGTCAAGCTTCACCGTGTGTGCTATCTTCAAAATCGAC CTTTCACGCATCCCTCGGGCGGCCTACCCCCTCGTGGTTCTTGCCATGAGTCTTGAGCACATCTTCCGGCTCATC AATGCCGTCATTCTCATCCCCTTCGAGGATAGCGTGAGCCACAGGATAGGCAAAGCATTCGGGGAGACTGCTCCA ATCGCATTGGCAAGCACGCTTCAAAACGTTCTCATGCTCGCTGGTCTCTCGCGCCTGGTGTCACCGGGGGTGTCT GGCTTTTGCGTGTTTGCTGCCATTGCGATTGTGTTCGACTTCTTTTACCTGAGCACCTTCTTCCTGTCAGTCCTC AGTGTCGACGTACGCAGAATGGAGCTCGTCGACGCGCTTGCCAAGGCATCGATGCGACGAAACCCCAGTGACCCA GGCGTCCGCGGCAGCCGTCGGTCCTGGTGGGACCCCGTCTTCCATGGCAAGATCGCCATGTCAACACGCATCGCG GGCACAATTGTCATGTTTGGTTTCGTCCTCCTCACTTGA |
| Transcript | >Hirsu2|3550 ATGATCTGGTATCTGCTGTACCCGCTTCGAGGAACAACGGAGGCTCCCACCCTCCCTACTTCGCATCCTCTGTAC GGCGTATTTGCTCGCTATGGCCGCTATGCCACACGTCATGTCGTCGCCACATTGCTGGTCTCGGCCGCCGTGGCC ACCATCCTAATCTACCCTATCCCGTTTCTCTTTACTAGCGACTACATCAACGGCGCCTCAAACTTGCCCAAACAT GTCTGGACCGTCGCCCAGCCTCTGCCGTATGACAACACTGTCGAGCCAGACATAATCATGCGCTCCATGTGGGTG CACGCTAGCTACATGCAGGCCTTGAACGCTGAACTCCTCGTCTCAGCTCTCGAGCTCCAGGACGACCTGCTTGGC ATCACGAAGAACTTCAGCCCCGCCCGTTCTCGCCGCGCACCCCTGACGGATGACTTGCTTGAACAAGGCATGTCG CTGTCCCAACGAGACGCCATACATGTCGCCAACGGGCTGACCCCAAACTCGTGGTTTTTCCACTCACCCTTACTG TATTGGAGCTGCTCGCGCGACCGCATTTTGGCCGACGATGACATCCTCTCCACCGTCAATGACAAGAAGAACCAG TCCACATCCGCCAATGTCACTTTACGTCACTCGATTGTCTTCAGCGGCAAGCGCTTCGAGGACCGCCGTCTGCTG GCCGCCGACGCCCTTGTCATCACACTACTCCACCTTCGCGATTCCCCTGTGGGACGTGGGTGGGAGAGAAGAGCA CTGGAGCTTCCAGAAAAGCTCTACGAGTTTCAGTTCCGACCAATCTCAATGCAGGACATTGCCAGTCTCGCCGTC GCATATGGCCTGACGCTGCTCTATTTTCTCAACAGTCTCTCAAAGCTCCGGGCCGTCAAGTCTAAAGTCGGCCTC ATTGTCACCATCATGGTGCAGATAATTTTATCGGTCATGTCAAGCTTCACCGTGTGTGCTATCTTCAAAATCGAC CTTTCACGCATCCCTCGGGCGGCCTACCCCCTCGTGGTTCTTGCCATGAGTCTTGAGCACATCTTCCGGCTCATC AATGCCGTCATTCTCATCCCCTTCGAGGATAGCGTGAGCCACAGGATAGGCAAAGCATTCGGGGAGACTGCTCCA ATCGCATTGGCAAGCACGCTTCAAAACGTTCTCATGCTCGCTGGTCTCTCGCGCCTGGTGTCACCGGGGGTGTCT GGCTTTTGCGTGTTTGCTGCCATTGCGATTGTGTTCGACTTCTTTTACCTGAGCACCTTCTTCCTGTCAGTCCTC AGTGTCGACGTACGCAGAATGGAGCTCGTCGACGCGCTTGCCAAGGCATCGATGCGACGAAACCCCAGTGACCCA GGCGTCCGCGGCAGCCGTCGGTCCTGGTGGGACCCCGTCTTCCATGGCAAGATCGCCATGTCAACACGCATCGCG GGCACAATTGTCATGTTTGGTTTCGTCCTCCTCACTTGA |
| Gene | >Hirsu2|3550 ATGATCTGGTATCTGCTGTACCCGCTTCGAGGGTGAGAACTGACCAGTTCCCCGCCTCCTGCCTTCATGCCTCCC TCCCTTTGCCCGCGAGGCATAGCTAGGCACCGTTGCTACAACCCTCTTGTGGTGTCTCCAGGCCGACTGCCTACC ACTATCGGCAGCTAACCCTCCTCCCTCCTAGAACAACGGAGGCTCCCACCCTCCCTACTTCGCATCCTCTGTACG GCGTATTTGCTCGCTATGGCCGCTATGCCACACGTCATGTCGTCGCCACATTGCTGGTCTCGGCCGCCGTGGCCA CCATCCTAATCTACCCTATCCCGTTTCTCTTTACTAGCGACTACATCAACGGCGCCTCAAACTTGCCCAAACATG TCTGGACCGTCGCCCAGCCTCTGCCGTATGACAACACTGTCGAGCCAGACATAATCATGCGCTCCATGTGGGTGC ACGCTAGCTACATGCAGGCCTTGAACGCTGAACTCCTCGTCTCAGCTCTCGAGCTCCAGGACGACCTGCTTGGCA TCACGAAGAACTTCAGCCCCGCCCGTTCTCGCCGCGCACCCCTGACGGATGACTTGCTTGAACAAGGCATGTCGC TGTCCCAACGAGACGCCATACATGTCGCCAACGGGCTGACCCCAAACTCGTGGTTTTTCCACTCACCCTTACTGT ATTGGAGCTGCTCGCGCGACCGCATTTTGGCCGACGATGACATCCTCTCCACCGTCAATGACAAGAAGAACCAGT CCACATCCGCCAATGTCACTTTACGTCACTCGATTGTCTTCAGCGGCAAGCGCTTCGAGGACCGCCGTCTGCTGG CCGCCGACGCCCTTGTCATCACACTACTCCACCTTCGCGATTCCCCTGTGGGACGTGGGTGGGAGAGAAGAGCAC TGGAGCTTCCAGAAAAGGTAGGAGACAAATGGAGCATATATCCCGCGGACGGTCGCGTAACTTCCAGCCAGCTCT ACGAGTTTCAGTTCCGACCAATCTCAATGCAGGACATTGCCAGTCTCGCCGTCGCATATGGCCTGACGCTGCTCT ATTTTCTCAACAGTCTCTCAAAGCTCCGGGCCGTCAAGTCTAAAGTCGGCCTCATTGTCACCATCATGGTGCAGA TAATTTTATCGGTCATGTCAAGCTTCACCGTGTGTGCTATCTTCAAAATCGACCTTTCACGCATCCCTCGGGCGG CCTACCCCCTCGTGGTTCTTGCCATGAGTCTTGAGCACATCTTCCGGCTCATCAATGCCGTCATTCTCATCCCCT TCGAGGATAGCGTGAGCCACAGGATAGGCAAAGCATTCGGGGAGACTGCTCCAATCGCATTGGCAAGCACGCTTC AAAACGTTCTCATGCTCGCTGGTCTCTCGCGCCTGGTGTCACCGGGGGTGTCTGGCTTTTGCGTGTTTGCTGCCA TTGCGATTGTGTTCGACTTCTTTTACCTGAGCACCTTCTTCCTGTCAGTCCTCAGTGTCGACGTACGCAGAATGG AGCTCGTCGACGCGCTTGCCAAGGCATCGATGCGACGAAACCCCAGTGACCCAGGCGTCCGCGGCAGCCGTCGGT CCTGGTGGGACCCCGTCTTCCATGGCAAGATCGCCATGTCAACACGCATCGCGGGCACAATTGTCATGTTTGGTT TCGTACTTATCGCCCAGTGGCATTTTTTTGGAGATGAGGGCTTGTTCCGAAAAATCCTGCGACTTTACAAGTGGG CCGACCCCCAGCTGGCACTCGGGCGCTCCAGGTCCTCCTCACTTGA |