© 2023 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|2278 |
| Gene name | |
| Location | Contig_1533:1198..4842 |
| Strand | - |
| Gene length (bp) | 3644 |
| Transcript length (bp) | 3552 |
| Coding sequence length (bp) | 3552 |
| Protein length (aa) | 1184 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF00617 | RasGEF | RasGEF domain | 1.6E-52 | 893 | 1082 |
| PF00618 | RasGEF_N | RasGEF N-terminal motif | 3.9E-16 | 714 | 799 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q54PQ4|GEFA_DICDI | Ras guanine nucleotide exchange factor A OS=Dictyostelium discoideum GN=gefA PE=2 SV=1 | 710 | 1142 | 5.0E-51 |
| sp|P04821|CDC25_YEAST | Cell division control protein 25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC25 PE=1 SV=1 | 690 | 1176 | 3.0E-50 |
| sp|Q02342|CDC25_LACKL | Cell division control protein 25 (Fragment) OS=Lachancea kluyveri GN=CDC25 PE=3 SV=1 | 699 | 1141 | 2.0E-47 |
| sp|P43069|CDC25_CANAL | Cell division control protein 25 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC25 PE=3 SV=1 | 699 | 1145 | 8.0E-47 |
| sp|Q62245|SOS1_MOUSE | Son of sevenless homolog 1 OS=Mus musculus GN=Sos1 PE=1 SV=2 | 715 | 1141 | 2.0E-40 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|Q54PQ4|GEFA_DICDI | Ras guanine nucleotide exchange factor A OS=Dictyostelium discoideum GN=gefA PE=2 SV=1 | 710 | 1142 | 5.0E-51 |
| sp|P04821|CDC25_YEAST | Cell division control protein 25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CDC25 PE=1 SV=1 | 690 | 1176 | 3.0E-50 |
| sp|Q02342|CDC25_LACKL | Cell division control protein 25 (Fragment) OS=Lachancea kluyveri GN=CDC25 PE=3 SV=1 | 699 | 1141 | 2.0E-47 |
| sp|P43069|CDC25_CANAL | Cell division control protein 25 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=CDC25 PE=3 SV=1 | 699 | 1145 | 8.0E-47 |
| sp|Q62245|SOS1_MOUSE | Son of sevenless homolog 1 OS=Mus musculus GN=Sos1 PE=1 SV=2 | 715 | 1141 | 2.0E-40 |
| sp|Q07890|SOS2_HUMAN | Son of sevenless homolog 2 OS=Homo sapiens GN=SOS2 PE=1 SV=2 | 715 | 1141 | 2.0E-40 |
| sp|B3LTF3|SDC25_YEAS1 | Guanine nucleotide exchange factor SDC25 OS=Saccharomyces cerevisiae (strain RM11-1a) GN=SDC25 PE=3 SV=1 | 697 | 1141 | 4.0E-40 |
| sp|A7A0P0|SDC25_YEAS7 | Guanine nucleotide exchange factor SDC25 OS=Saccharomyces cerevisiae (strain YJM789) GN=SDC25 PE=3 SV=2 | 697 | 1141 | 4.0E-40 |
| sp|B5VMS9|SDC25_YEAS6 | Guanine nucleotide exchange factor SDC25 OS=Saccharomyces cerevisiae (strain AWRI1631) GN=SDC25 PE=3 SV=1 | 697 | 1141 | 4.0E-40 |
| sp|Q02384|SOS2_MOUSE | Son of sevenless homolog 2 OS=Mus musculus GN=Sos2 PE=1 SV=2 | 715 | 1141 | 6.0E-40 |
| sp|C8ZCV7|SDC25_YEAS8 | Guanine nucleotide exchange factor SDC25 OS=Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) GN=SDC25 PE=3 SV=1 | 697 | 1141 | 1.0E-39 |
| sp|Q07889|SOS1_HUMAN | Son of sevenless homolog 1 OS=Homo sapiens GN=SOS1 PE=1 SV=1 | 715 | 1141 | 4.0E-39 |
| sp|P0CF34|YL016_YEAST | Putative truncated guanine nucleotide exchange factor SDC25 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SDC25 PE=5 SV=1 | 697 | 1141 | 4.0E-39 |
| sp|P26675|SOS_DROME | Protein son of sevenless OS=Drosophila melanogaster GN=Sos PE=1 SV=2 | 715 | 1141 | 1.0E-38 |
| sp|P0CF32|SDC25_YEASX | Guanine nucleotide exchange factor SDC25 OS=Saccharomyces cerevisiae GN=SDC25 PE=3 SV=1 | 697 | 1141 | 2.0E-38 |
| sp|A2CEA7|RGRF2_DANRE | Ras-specific guanine nucleotide-releasing factor 2 OS=Danio rerio GN=rasgrf2 PE=3 SV=1 | 779 | 1141 | 5.0E-36 |
| sp|Q13972|RGRF1_HUMAN | Ras-specific guanine nucleotide-releasing factor 1 OS=Homo sapiens GN=RASGRF1 PE=1 SV=2 | 779 | 1141 | 7.0E-35 |
| sp|Q8IS14|GEFJ_DICDI | Ras guanine nucleotide exchange factor J OS=Dictyostelium discoideum GN=gefJ PE=2 SV=1 | 714 | 1141 | 1.0E-34 |
| sp|Q8IS15|GEFI_DICDI | Ras guanine nucleotide exchange factor I OS=Dictyostelium discoideum GN=gefI PE=2 SV=1 | 714 | 1141 | 1.0E-34 |
| sp|O14827|RGRF2_HUMAN | Ras-specific guanine nucleotide-releasing factor 2 OS=Homo sapiens GN=RASGRF2 PE=1 SV=2 | 779 | 1141 | 2.0E-34 |
| sp|P28818|RGRF1_RAT | Ras-specific guanine nucleotide-releasing factor 1 OS=Rattus norvegicus GN=Rasgrf1 PE=1 SV=1 | 779 | 1141 | 2.0E-34 |
| sp|Q54TK8|GEFP_DICDI | Ras guanine nucleotide exchange factor P OS=Dictyostelium discoideum GN=gefP PE=2 SV=1 | 714 | 1143 | 3.0E-34 |
| sp|P27671|RGRF1_MOUSE | Ras-specific guanine nucleotide-releasing factor 1 OS=Mus musculus GN=Rasgrf1 PE=1 SV=2 | 779 | 1141 | 3.0E-34 |
| sp|P26674|STE6_SCHPO | Protein ste6 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ste6 PE=3 SV=1 | 862 | 1143 | 1.0E-33 |
| sp|Q552M5|GEFY_DICDI | Ras guanine nucleotide exchange factor Y OS=Dictyostelium discoideum GN=gefY PE=1 SV=2 | 714 | 1054 | 2.0E-33 |
| sp|Q99JE4|RGRF2_RAT | Ras-specific guanine nucleotide-releasing factor 2 OS=Rattus norvegicus GN=Rasgrf2 PE=1 SV=1 | 779 | 1141 | 3.0E-33 |
| sp|Q8IS18|GEFE_DICDI | Ras guanine nucleotide exchange factor E OS=Dictyostelium discoideum GN=gefE PE=2 SV=1 | 776 | 1054 | 6.0E-33 |
| sp|P70392|RGRF2_MOUSE | Ras-specific guanine nucleotide-releasing factor 2 OS=Mus musculus GN=Rasgrf2 PE=1 SV=2 | 779 | 1141 | 9.0E-33 |
| sp|B0M0P8|GEFL_DICDI | Ras guanine nucleotide exchange factor L OS=Dictyostelium discoideum GN=gefL PE=2 SV=1 | 713 | 1097 | 3.0E-32 |
| sp|Q55FD8|GEFV_DICDI | Ras guanine nucleotide exchange factor V OS=Dictyostelium discoideum GN=gefV PE=2 SV=1 | 704 | 1112 | 3.0E-31 |
| sp|Q8SSQ3|GEFM_DICDI | Ras guanine nucleotide exchange factor M OS=Dictyostelium discoideum GN=gefM PE=2 SV=1 | 867 | 1097 | 5.0E-31 |
| sp|Q8SSQ0|GEFR_DICDI | Ras guanine nucleotide exchange factor R OS=Dictyostelium discoideum GN=gefR PE=1 SV=1 | 712 | 1143 | 6.0E-31 |
| sp|Q55GH9|GEFW_DICDI | Ras guanine nucleotide exchange factor W OS=Dictyostelium discoideum GN=gefW PE=2 SV=1 | 715 | 1104 | 4.0E-29 |
| sp|Q54FF3|GEFK_DICDI | Ras guanine nucleotide exchange factor K OS=Dictyostelium discoideum GN=gefK PE=2 SV=1 | 880 | 1141 | 2.0E-28 |
| sp|Q8IS20|GEFC_DICDI | Ras guanine nucleotide exchange factor C OS=Dictyostelium discoideum GN=gefC PE=2 SV=1 | 886 | 1097 | 4.0E-28 |
| sp|Q86G47|GEFQ_DICDI | Ras guanine nucleotide exchange factor Q OS=Dictyostelium discoideum GN=gefQ PE=2 SV=1 | 849 | 1116 | 3.0E-27 |
| sp|Q9USU1|EFC25_SCHPO | Ras guanine nucleotide exchange factor efc25 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=efc25 PE=1 SV=1 | 712 | 1143 | 3.0E-27 |
| sp|Q4R7W3|RGPS2_MACFA | Ras-specific guanine nucleotide-releasing factor RalGPS2 OS=Macaca fascicularis GN=RALGPS2 PE=2 SV=1 | 886 | 1167 | 7.0E-26 |
| sp|Q86X27|RGPS2_HUMAN | Ras-specific guanine nucleotide-releasing factor RalGPS2 OS=Homo sapiens GN=RALGPS2 PE=1 SV=1 | 886 | 1167 | 1.0E-25 |
| sp|Q5ZJK0|RGPS1_CHICK | Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Gallus gallus GN=RALGPS1 PE=2 SV=1 | 886 | 1140 | 2.0E-25 |
| sp|Q9ERD6|RGPS2_MOUSE | Ras-specific guanine nucleotide-releasing factor RalGPS2 OS=Mus musculus GN=Ralgps2 PE=1 SV=2 | 886 | 1167 | 2.0E-25 |
| sp|Q60695|RGL1_MOUSE | Ral guanine nucleotide dissociation stimulator-like 1 OS=Mus musculus GN=Rgl1 PE=1 SV=2 | 715 | 1097 | 6.0E-25 |
| sp|Q9NZL6|RGL1_HUMAN | Ral guanine nucleotide dissociation stimulator-like 1 OS=Homo sapiens GN=RGL1 PE=1 SV=1 | 715 | 1097 | 1.0E-24 |
| sp|Q8IS21|GEFB_DICDI | Ras guanine nucleotide exchange factor B OS=Dictyostelium discoideum GN=gefB PE=2 SV=1 | 861 | 1143 | 1.0E-23 |
| sp|Q8ST25|GEFG_DICDI | Ras guanine nucleotide exchange factor G OS=Dictyostelium discoideum GN=gefG PE=2 SV=1 | 719 | 1112 | 5.0E-23 |
| sp|Q5JS13|RGPS1_HUMAN | Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Homo sapiens GN=RALGPS1 PE=1 SV=1 | 886 | 1162 | 1.0E-22 |
| sp|Q8IS16|GEFH_DICDI | Ras guanine nucleotide exchange factor H OS=Dictyostelium discoideum GN=gefH PE=2 SV=1 | 695 | 1113 | 1.0E-22 |
| sp|Q6P112|RGL1_DANRE | Ral guanine nucleotide dissociation stimulator-like 1 OS=Danio rerio GN=rgl1 PE=2 SV=1 | 715 | 1115 | 1.0E-22 |
| sp|B0UXH6|RGPS1_DANRE | Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Danio rerio GN=ralgps1 PE=2 SV=1 | 886 | 1158 | 2.0E-22 |
| sp|Q3UYI5|RGL3_MOUSE | Ral guanine nucleotide dissociation stimulator-like 3 OS=Mus musculus GN=Rgl3 PE=1 SV=2 | 720 | 1140 | 1.0E-21 |
| sp|Q8TEU7|RPGF6_HUMAN | Rap guanine nucleotide exchange factor 6 OS=Homo sapiens GN=RAPGEF6 PE=1 SV=2 | 882 | 1096 | 1.0E-21 |
| sp|A2AR50|RGPS1_MOUSE | Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Mus musculus GN=Ralgps1 PE=1 SV=2 | 886 | 1162 | 1.0E-21 |
| sp|F1MSG6|RPGF2_BOVIN | Rap guanine nucleotide exchange factor 2 OS=Bos taurus GN=RAPGEF2 PE=1 SV=2 | 882 | 1096 | 2.0E-21 |
| sp|F1M386|RPGF2_RAT | Rap guanine nucleotide exchange factor 2 OS=Rattus norvegicus GN=Rapgef2 PE=1 SV=2 | 882 | 1096 | 3.0E-21 |
| sp|Q8SSW7|GEFS_DICDI | Ras guanine nucleotide exchange factor S OS=Dictyostelium discoideum GN=gefS PE=2 SV=1 | 711 | 1100 | 3.0E-21 |
| sp|F1PBJ0|RPGF2_CANLF | Rap guanine nucleotide exchange factor 2 OS=Canis lupus familiaris GN=RAPGEF2 PE=1 SV=2 | 882 | 1096 | 3.0E-21 |
| sp|Q8CHG7|RPGF2_MOUSE | Rap guanine nucleotide exchange factor 2 OS=Mus musculus GN=Rapgef2 PE=1 SV=2 | 882 | 1096 | 3.0E-21 |
| sp|Q9Y4G8|RPGF2_HUMAN | Rap guanine nucleotide exchange factor 2 OS=Homo sapiens GN=RAPGEF2 PE=1 SV=1 | 882 | 1096 | 5.0E-21 |
| sp|Q54S40|GBPD_DICDI | Cyclic GMP-binding protein D OS=Dictyostelium discoideum GN=gbpD PE=2 SV=1 | 889 | 1057 | 6.0E-21 |
| sp|Q6DBW1|RG1BB_DANRE | Ras-GEF domain-containing family member 1B-B OS=Danio rerio GN=rasgef1bb PE=2 SV=1 | 711 | 1093 | 2.0E-20 |
| sp|P83900|RPGF5_RAT | Rap guanine nucleotide exchange factor 5 OS=Rattus norvegicus GN=Rapgef5 PE=2 SV=1 | 883 | 1089 | 2.0E-20 |
| sp|Q92565|RPGF5_HUMAN | Rap guanine nucleotide exchange factor 5 OS=Homo sapiens GN=RAPGEF5 PE=1 SV=1 | 883 | 1093 | 3.0E-20 |
| sp|Q8C0Q9|RPGF5_MOUSE | Rap guanine nucleotide exchange factor 5 OS=Mus musculus GN=Rapgef5 PE=2 SV=2 | 883 | 1089 | 4.0E-20 |
| sp|O77086|C3G_DROME | Guanine nucleotide-releasing factor 2 OS=Drosophila melanogaster GN=C3G PE=1 SV=4 | 884 | 1104 | 7.0E-20 |
| sp|G5EDB9|RPGF_CAEEL | Rap guanine nucleotide exchange factor OS=Caenorhabditis elegans GN=pxf-1 PE=1 SV=1 | 886 | 1102 | 2.0E-19 |
| sp|Q8IS11|GEFO_DICDI | Ras guanine nucleotide exchange factor O OS=Dictyostelium discoideum GN=gefO PE=2 SV=1 | 888 | 1116 | 2.0E-19 |
| sp|Q03386|GNDS_RAT | Ral guanine nucleotide dissociation stimulator OS=Rattus norvegicus GN=Ralgds PE=1 SV=1 | 859 | 1097 | 3.0E-19 |
| sp|Q13905|RPGF1_HUMAN | Rap guanine nucleotide exchange factor 1 OS=Homo sapiens GN=RAPGEF1 PE=1 SV=3 | 686 | 1097 | 1.0E-18 |
| sp|Q6DHR3|RG1BA_DANRE | Ras-GEF domain-containing family member 1B-A OS=Danio rerio GN=rasgef1ba PE=2 SV=2 | 705 | 1097 | 3.0E-18 |
| sp|Q03385|GNDS_MOUSE | Ral guanine nucleotide dissociation stimulator OS=Mus musculus GN=Ralgds PE=1 SV=2 | 859 | 1097 | 3.0E-18 |
| sp|Q3MIN7|RGL3_HUMAN | Ral guanine nucleotide dissociation stimulator-like 3 OS=Homo sapiens GN=RGL3 PE=1 SV=2 | 884 | 1097 | 4.0E-18 |
| sp|Q12967|GNDS_HUMAN | Ral guanine nucleotide dissociation stimulator OS=Homo sapiens GN=RALGDS PE=1 SV=2 | 859 | 1127 | 3.0E-17 |
| sp|Q9D300|RGF1C_MOUSE | Ras-GEF domain-containing family member 1C OS=Mus musculus GN=Rasgef1c PE=2 SV=1 | 712 | 1110 | 8.0E-17 |
| sp|Q28EC1|RGF1B_XENTR | Ras-GEF domain-containing family member 1B OS=Xenopus tropicalis GN=rasgef1b PE=2 SV=1 | 708 | 1106 | 1.0E-16 |
| sp|Q95KH6|RGF1C_MACFA | Ras-GEF domain-containing family member 1C OS=Macaca fascicularis GN=RASGEF1C PE=2 SV=1 | 712 | 1110 | 2.0E-16 |
| sp|Q8MVR1|GBPC_DICDI | Cyclic GMP-binding protein C OS=Dictyostelium discoideum GN=gbpC PE=1 SV=1 | 886 | 1167 | 7.0E-16 |
| sp|Q9UHV5|RPGFL_HUMAN | Rap guanine nucleotide exchange factor-like 1 OS=Homo sapiens GN=RAPGEFL1 PE=1 SV=2 | 890 | 1055 | 1.0E-15 |
| sp|A4IFE4|RGF1B_BOVIN | Ras-GEF domain-containing family member 1B OS=Bos taurus GN=RASGEF1B PE=2 SV=1 | 708 | 1106 | 2.0E-15 |
| sp|Q5RC04|RGF1B_PONAB | Ras-GEF domain-containing family member 1B OS=Pongo abelii GN=RASGEF1B PE=2 SV=2 | 708 | 1106 | 3.0E-15 |
| sp|Q61193|RGL2_MOUSE | Ral guanine nucleotide dissociation stimulator-like 2 OS=Mus musculus GN=Rgl2 PE=1 SV=2 | 886 | 1180 | 3.0E-15 |
| sp|O15211|RGL2_HUMAN | Ral guanine nucleotide dissociation stimulator-like 2 OS=Homo sapiens GN=RGL2 PE=1 SV=1 | 714 | 1112 | 4.0E-15 |
| sp|Q0VAM2|RGF1B_HUMAN | Ras-GEF domain-containing family member 1B OS=Homo sapiens GN=RASGEF1B PE=1 SV=2 | 708 | 1106 | 4.0E-15 |
| sp|Q8IZJ4|RGDSR_HUMAN | Ral-GDS-related protein OS=Homo sapiens GN=RGL4 PE=2 SV=1 | 884 | 1140 | 4.0E-15 |
| sp|Q8N431|RGF1C_HUMAN | Ras-GEF domain-containing family member 1C OS=Homo sapiens GN=RASGEF1C PE=2 SV=2 | 712 | 1110 | 5.0E-15 |
| sp|Q5R9B2|RPGFL_PONPY | Rap guanine nucleotide exchange factor-like 1 OS=Pongo pygmaeus GN=RAPGEFL1 PE=2 SV=1 | 890 | 1055 | 7.0E-15 |
| sp|Q8JZL7|RGF1B_MOUSE | Ras-GEF domain-containing family member 1B OS=Mus musculus GN=Rasgef1b PE=1 SV=1 | 708 | 1106 | 9.0E-15 |
| sp|Q8WZA2|RPGF4_HUMAN | Rap guanine nucleotide exchange factor 4 OS=Homo sapiens GN=RAPGEF4 PE=1 SV=1 | 893 | 1055 | 1.0E-14 |
| sp|A0JM95|RGF1A_XENTR | Ras-GEF domain-containing family member 1A OS=Xenopus tropicalis GN=rasgef1a PE=2 SV=1 | 711 | 1051 | 1.0E-14 |
| sp|Q68EF8|RPGFL_MOUSE | Rap guanine nucleotide exchange factor-like 1 OS=Mus musculus GN=Rapgefl1 PE=1 SV=2 | 890 | 1055 | 1.0E-14 |
| sp|Q55EC7|GEFX_DICDI | RasGEF domain-containing serine/threonine-protein kinase X OS=Dictyostelium discoideum GN=gefX PE=2 SV=1 | 886 | 1113 | 1.0E-14 |
| sp|Q9Z1C8|RPGF3_RAT | Rap guanine nucleotide exchange factor 3 OS=Rattus norvegicus GN=Rapgef3 PE=2 SV=2 | 957 | 1086 | 2.0E-14 |
| sp|Q8VCC8|RPGF3_MOUSE | Rap guanine nucleotide exchange factor 3 OS=Mus musculus GN=Rapgef3 PE=1 SV=2 | 957 | 1086 | 2.0E-14 |
| sp|Q8IS12|GEFN_DICDI | Ras guanine nucleotide exchange factor N OS=Dictyostelium discoideum GN=gefN PE=2 SV=1 | 668 | 1096 | 3.0E-14 |
| sp|Q9Z1C7|RPGF4_RAT | Rap guanine nucleotide exchange factor 4 (Fragment) OS=Rattus norvegicus GN=Rapgef4 PE=2 SV=1 | 893 | 1055 | 4.0E-14 |
| sp|Q32N25|GRP2A_XENLA | RAS guanyl-releasing protein 2-A OS=Xenopus laevis GN=rasgrp2-a PE=2 SV=1 | 889 | 1141 | 7.0E-14 |
| sp|O95398|RPGF3_HUMAN | Rap guanine nucleotide exchange factor 3 OS=Homo sapiens GN=RAPGEF3 PE=1 SV=6 | 957 | 1055 | 7.0E-14 |
| sp|Q9EQZ6|RPGF4_MOUSE | Rap guanine nucleotide exchange factor 4 OS=Mus musculus GN=Rapgef4 PE=1 SV=1 | 893 | 1055 | 8.0E-14 |
| sp|Q5TJE5|RGL2_CANLF | Ral guanine nucleotide dissociation stimulator-like 2 OS=Canis lupus familiaris GN=RGL2 PE=3 SV=1 | 714 | 1112 | 9.0E-14 |
| sp|Q8N9B8|RGF1A_HUMAN | Ras-GEF domain-containing family member 1A OS=Homo sapiens GN=RASGEF1A PE=2 SV=2 | 706 | 1051 | 1.0E-13 |
| sp|Q6DCK3|GRP2B_XENLA | RAS guanyl-releasing protein 2-B OS=Xenopus laevis GN=rasgrp2-b PE=2 SV=1 | 889 | 1141 | 2.0E-13 |
| sp|Q6CY10|LTE1_KLULA | Guanine nucleotide exchange factor LTE1 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) GN=LTE1 PE=3 SV=1 | 884 | 1050 | 4.0E-13 |
| sp|P0C643|GRP2_RAT | RAS guanyl-releasing protein 2 OS=Rattus norvegicus GN=Rasgrp2 PE=1 SV=1 | 889 | 1056 | 3.0E-12 |
| sp|Q9QUG9|GRP2_MOUSE | RAS guanyl-releasing protein 2 OS=Mus musculus GN=Rasgrp2 PE=1 SV=2 | 889 | 1056 | 3.0E-12 |
| sp|Q7LDG7|GRP2_HUMAN | RAS guanyl-releasing protein 2 OS=Homo sapiens GN=RASGRP2 PE=1 SV=1 | 889 | 1056 | 3.0E-12 |
| sp|A6N9I4|GRP2_BOVIN | RAS guanyl-releasing protein 2 OS=Bos taurus GN=RASGRP2 PE=2 SV=1 | 889 | 1056 | 3.0E-12 |
| sp|Q54C94|GEFF_DICDI | Ras guanine nucleotide exchange factor F OS=Dictyostelium discoideum GN=gefF PE=2 SV=1 | 710 | 1105 | 4.0E-12 |
| sp|Q8IS19|GEFD_DICDI | Ras guanine nucleotide exchange factor D OS=Dictyostelium discoideum GN=gefD PE=2 SV=1 | 894 | 1055 | 2.0E-11 |
| sp|P07866|LTE1_YEAST | Guanine nucleotide exchange factor LTE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LTE1 PE=1 SV=2 | 851 | 1097 | 5.0E-11 |
| sp|Q6FT12|LTE1_CANGA | Guanine nucleotide exchange factor LTE1 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=LTE1 PE=3 SV=1 | 884 | 1116 | 6.0E-11 |
| sp|P25300|BUD5_YEAST | Bud site selection protein 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BUD5 PE=1 SV=2 | 887 | 1097 | 1.0E-10 |
| sp|Q75BH9|LTE1_ASHGO | Guanine nucleotide exchange factor LTE1 OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) GN=LTE1 PE=3 SV=1 | 884 | 1097 | 3.0E-10 |
| sp|Q6NTL4|GRP1_XENLA | RAS guanyl-releasing protein 1 OS=Xenopus laevis GN=rasgrp1 PE=2 SV=1 | 889 | 1048 | 6.0E-09 |
| sp|P34578|RPGF1_CAEEL | Rap guanine nucleotide exchange factor 1 OS=Caenorhabditis elegans GN=epac-1 PE=3 SV=3 | 955 | 1146 | 8.0E-08 |
| sp|Q8IV61|GRP3_HUMAN | Ras guanyl-releasing protein 3 OS=Homo sapiens GN=RASGRP3 PE=1 SV=1 | 885 | 1156 | 1.0E-07 |
| sp|A4IJ06|GRP1_XENTR | RAS guanyl-releasing protein 1 OS=Xenopus tropicalis GN=rasgrp1 PE=2 SV=1 | 889 | 1048 | 1.0E-07 |
| sp|Q8IS20|GEFC_DICDI | Ras guanine nucleotide exchange factor C OS=Dictyostelium discoideum GN=gefC PE=2 SV=1 | 714 | 794 | 2.0E-07 |
| sp|O95267|GRP1_HUMAN | RAS guanyl-releasing protein 1 OS=Homo sapiens GN=RASGRP1 PE=1 SV=2 | 889 | 1048 | 9.0E-07 |
| sp|Q8TDF6|GRP4_HUMAN | RAS guanyl-releasing protein 4 OS=Homo sapiens GN=RASGRP4 PE=1 SV=2 | 887 | 1056 | 2.0E-06 |
| sp|Q1LZ97|GRP4_BOVIN | RAS guanyl-releasing protein 4 OS=Bos taurus GN=RASGRP4 PE=2 SV=1 | 887 | 1056 | 3.0E-06 |
| sp|Q9R1K8|GRP1_RAT | RAS guanyl-releasing protein 1 OS=Rattus norvegicus GN=Rasgrp1 PE=1 SV=1 | 889 | 1048 | 4.0E-06 |
| sp|Q9Z1S3|GRP1_MOUSE | RAS guanyl-releasing protein 1 OS=Mus musculus GN=Rasgrp1 PE=1 SV=1 | 889 | 1048 | 5.0E-06 |
| sp|Q8BTM9|GRP4_MOUSE | RAS guanyl-releasing protein 4 OS=Mus musculus GN=Rasgrp4 PE=1 SV=1 | 887 | 1056 | 5.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0007264 | small GTPase mediated signal transduction | Yes |
| GO:0005085 | guanyl-nucleotide exchange factor activity | Yes |
| GO:0050789 | regulation of biological process | No |
| GO:0009987 | cellular process | No |
| GO:0007165 | signal transduction | No |
| GO:0060589 | nucleoside-triphosphatase regulator activity | No |
| GO:0030695 | GTPase regulator activity | No |
| GO:0098772 | molecular function regulator activity | No |
| GO:0008150 | biological_process | No |
| GO:0030234 | enzyme regulator activity | No |
| GO:0065007 | biological regulation | No |
| GO:0003674 | molecular_function | No |
| GO:0050794 | regulation of cellular process | No |
| GO:0035556 | intracellular signal transduction | No |
| Localizations | Signals | Cytoplasm | Nucleus | Extracellular | Cell membrane | Mitochondrion | Plastid | Endoplasmic reticulum | Lysosome vacuole | Golgi apparatus | Peroxisome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytoplasm | 0.7073 | 0.3639 | 0.143 | 0.3231 | 0.0556 | 0.0047 | 0.0734 | 0.3723 | 0.2715 | 0.0051 |
| Orthofinder run ID | 4 |
| Orthogroup | 2019 |
| Change Orthofinder run |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|2278 MTPPATPNGSQEDLSPEVLDPPVFHSFLRAFYPFSPSDAMTESSVTLPLDEGDVVLVHSVHTNGWADGTLLATGA RGWLPTNYCDAYEPDDMRSLLKALLNFWDLLRSTSINDNEIFRNQEFMKGIIAGVRFLLERTHCLSRESAVVLRS DPLRKSRKSLLSELSLLVKTAKRLQESQKRTLEPAEDVNDIIDEMILKAFKIVTKGVRFLDILDEDRRSRAPAAV TVMATVAEESCVPPTPPADQMSFDDNHARGRSGDVSSQDTSEDTRAASTVASESSEASGAQVKATPWGRRLSSLN APVHPGAPHAGSAQNRLSQGSQYQANRLSGSMAHRVSLAGPSPLSRPNHLASERLNRSHDKLLSHLGSFIGRLHL HSHSRPELALAIKLSAASGGELLTVIDGVCGYNSSNLNALGHVRTAMFDRIQALVHAASDILCHPTTEEGTDMIM PYDNNLLLMAATGCVRAAGECVAKAKAAIERAGDFEFELGDNALGLDLGVLDAVMQERSRTPSVADRSDVSVAES SSHIPEQPPVPRPRRPTMGAVDKPLPRVPKLSIPTEQQTRRSNSPVSSRPASANDDNASSAASSVSSVRPAPRAM PGLFNPPHPADLIPAADAARNEPDLQASRFDAIAASSAGSSATYLSRDSETSIVSQTSTRATTPDHGLAPRSQPS MSELSAAGSFSQAEEADDVETRLLERTYAHELMFNKEGQVTGGSLPALVERLTTHESTPDAAFVSTFYLTFRLFC TPIKLTEALIDRFDYVGESPHMSGPVRLRVYNVLKGWLESHWRDRTDRGALQLIIPFAEEKLGAAIPSAGNRLLE LAKRVSGDGLLVPRLVSSMGKTNTAIAQYVPADAPLPAPAISKSQLHALNAFRAGVSSPAILDFDPLEVARQLTV KQMAIFCSILPEELLASQWMKNGGADAPHVKAMSSLSTDLSNLVAETILQQHEIKKRAAVIKQWIKIAHHCHELH NYDGLMAIICSLNSSTISRLRKTWDAISLKRKEMLRAMQDIVEPSQNHKVLRTRLHDHVPPCLPFLGMYLTDLTF VDIGNPATKQMSLGTEADETGAGGLTVVNFDKHCRTAKIIGELQRFQIPYRLMEVPDMQEWLSAQIRRVRNSDQG NVQVTYYRKSLLLEPRETPSRRDHEPPTPISGSGGSRADLFGWMSRDRGGQTPTPAQG* |
| Coding | >Hirsu2|2278 ATGACACCCCCCGCAACCCCCAATGGCTCCCAGGAGGACCTGTCGCCCGAGGTCCTCGACCCGCCCGTTTTCCAC AGCTTCCTGCGGGCCTTCTATCCATTCAGCCCCAGCGATGCCATGACCGAGTCGAGCGTGACGCTGCCGCTTGAC GAGGGAGACGTCGTCCTCGTCCACTCCGTCCACACGAATGGATGGGCCGACGGGACCCTGCTGGCAACGGGCGCC AGGGGCTGGCTACCCACCAACTACTGCGACGCGTACGAGCCCGACGACATGCGAAGCCTGCTCAAGGCCCTCCTC AACTTCTGGGATCTTCTGCGGAGCACCTCCATCAACGACAATGAGATTTTCAGGAATCAAGAGTTCATGAAGGGC ATCATTGCCGGCGTCCGCTTCCTTCTGGAACGCACCCATTGTCTCAGCAGGGAATCTGCCGTCGTCCTGCGCAGC GATCCGCTCCGCAAGTCTCGAAAGTCGCTCCTCTCGGAACTTTCGCTGCTGGTCAAGACGGCGAAGCGGCTGCAG GAAAGCCAGAAGCGCACGCTCGAGCCCGCGGAAGACGTCAACGACATCATCGACGAGATGATTCTGAAGGCATTC AAGATCGTCACCAAGGGCGTCCGCTTCTTGGACATACTCGACGAGGACCGACGATCCCGCGCCCCGGCCGCCGTT ACCGTCATGGCCACCGTCGCCGAGGAGTCGTGCGTGCCTCCCACACCACCCGCCGACCAGATGAGCTTTGACGAC AATCACGCACGCGGCCGGTCGGGCGATGTCAGTTCCCAAGACACGTCCGAGGACACTCGCGCGGCCAGCACCGTT GCGTCGGAATCGAGCGAGGCCTCGGGAGCACAAGTCAAGGCGACCCCTTGGGGCAGGCGCCTGTCGTCGCTCAAC GCACCGGTTCATCCCGGCGCCCCCCACGCTGGATCGGCTCAGAACCGGCTATCTCAAGGCAGCCAGTACCAAGCC AACCGCCTCTCGGGCTCCATGGCGCACCGCGTGTCGCTGGCCGGTCCTTCGCCCTTGTCCAGGCCCAATCACCTG GCGTCCGAACGGCTCAACCGAAGCCACGACAAGCTACTGTCGCATCTTGGCTCCTTCATCGGCAGGTTGCACCTG CACTCACATTCCCGACCTGAGCTTGCGCTCGCCATCAAGCTGTCTGCCGCGTCGGGCGGAGAGCTCTTGACCGTC ATCGACGGCGTCTGCGGATACAACAGCTCGAACCTCAACGCGCTCGGCCATGTCCGCACCGCCATGTTCGACCGC ATACAGGCCCTGGTCCACGCTGCATCCGACATTCTGTGTCACCCGACGACCGAGGAGGGCACGGACATGATTATG CCGTACGACAACAACCTGCTGCTCATGGCGGCTACGGGATGCGTCCGCGCCGCCGGCGAGTGCGTGGCCAAGGCC AAGGCGGCCATCGAGAGGGCCGGGGACTTCGAGTTTGAACTGGGGGACAACGCGCTGGGCTTGGACCTCGGCGTC CTGGACGCCGTCATGCAGGAACGGTCGAGAACGCCGTCAGTCGCGGATCGGTCCGACGTAAGCGTCGCCGAGTCT TCCTCCCACATCCCGGAGCAGCCGCCGGTTCCGAGGCCGCGCCGGCCGACCATGGGCGCGGTCGACAAGCCGCTT CCCCGCGTCCCCAAACTCAGCATCCCGACGGAGCAGCAGACCCGGAGGAGCAACTCGCCCGTTTCGTCTCGACCT GCGTCGGCAAACGACGACAATGCGTCGAGCGCGGCGTCTTCCGTCTCGTCTGTCCGTCCCGCGCCGCGCGCCATG CCAGGCCTGTTCAACCCGCCACATCCTGCCGATCTCATCCCGGCGGCCGATGCGGCGAGGAACGAGCCCGACCTG CAGGCCTCGCGGTTCGACGCCATTGCGGCCTCGAGCGCCGGCAGCAGTGCCACCTATCTGAGCCGAGACTCGGAG ACGAGCATCGTCTCGCAGACGTCGACCCGCGCCACGACGCCGGACCATGGACTCGCGCCGCGCAGCCAGCCATCC ATGTCGGAGCTGAGCGCGGCTGGCAGTTTCTCGCAGGCCGAAGAGGCCGATGACGTCGAGACGAGGCTCTTGGAG AGGACCTATGCGCACGAGCTCATGTTCAACAAGGAGGGCCAGGTCACCGGCGGCTCCCTGCCGGCGCTTGTGGAG CGGCTCACCACCCACGAGTCCACGCCGGACGCCGCTTTCGTCTCGACCTTTTACCTCACCTTCAGACTCTTCTGC ACGCCGATCAAGCTGACGGAAGCCCTCATCGACCGCTTCGACTACGTGGGTGAATCCCCCCACATGTCGGGGCCG GTCCGCCTCCGGGTATACAACGTCTTGAAGGGATGGCTCGAGTCTCACTGGAGGGACCGCACCGACCGGGGGGCG CTGCAGCTTATCATCCCGTTCGCGGAGGAGAAGCTGGGCGCCGCGATCCCCTCGGCCGGGAACCGCCTCCTTGAG CTGGCGAAGCGGGTGTCCGGAGACGGCCTACTGGTGCCCCGGCTGGTGTCGTCGATGGGCAAGACGAACACGGCC ATCGCTCAGTATGTGCCGGCGGACGCGCCCCTGCCGGCGCCGGCCATCTCCAAGAGCCAGCTGCACGCGCTCAAC GCCTTCCGGGCGGGAGTCAGCTCGCCCGCCATACTAGACTTCGATCCGCTCGAGGTGGCCCGTCAGCTGACGGTC AAGCAGATGGCCATCTTCTGCTCCATCCTGCCGGAGGAGCTGCTGGCGTCGCAGTGGATGAAGAACGGCGGAGCC GACGCGCCGCACGTCAAGGCCATGTCGTCGTTGTCGACGGACCTGTCCAACCTGGTGGCCGAGACGATCCTCCAG CAACACGAGATCAAGAAGCGCGCGGCCGTCATCAAGCAGTGGATCAAGATCGCCCACCACTGCCACGAGCTGCAC AACTACGACGGGCTGATGGCCATCATCTGCAGCCTCAACAGCAGCACCATCAGCCGTCTTCGCAAGACGTGGGAC GCCATCTCCCTCAAGCGGAAGGAGATGCTGCGAGCCATGCAGGACATCGTGGAGCCGTCGCAGAACCACAAGGTG CTCCGGACTCGGCTTCACGACCACGTCCCGCCCTGCCTGCCCTTCCTCGGCATGTACCTGACGGACCTGACGTTT GTGGACATCGGCAACCCCGCCACCAAGCAGATGTCTCTCGGCACCGAGGCCGACGAGACCGGCGCGGGCGGCCTG ACCGTCGTCAACTTCGACAAGCACTGCCGCACGGCCAAGATCATCGGCGAGCTGCAGCGGTTCCAGATCCCATAC CGGCTGATGGAGGTGCCCGACATGCAGGAGTGGCTGTCGGCCCAGATCCGGCGAGTGCGCAACAGCGACCAGGGC AACGTCCAGGTCACGTACTATCGCAAGAGCCTGCTCCTGGAGCCCCGCGAGACGCCGTCTCGCCGCGACCACGAA CCGCCGACGCCTATCTCCGGGTCGGGAGGCTCGCGCGCGGATCTGTTTGGGTGGATGTCGCGCGATCGAGGTGGC CAGACTCCCACTCCGGCACAGGGGTGA |
| Transcript | >Hirsu2|2278 ATGACACCCCCCGCAACCCCCAATGGCTCCCAGGAGGACCTGTCGCCCGAGGTCCTCGACCCGCCCGTTTTCCAC AGCTTCCTGCGGGCCTTCTATCCATTCAGCCCCAGCGATGCCATGACCGAGTCGAGCGTGACGCTGCCGCTTGAC GAGGGAGACGTCGTCCTCGTCCACTCCGTCCACACGAATGGATGGGCCGACGGGACCCTGCTGGCAACGGGCGCC AGGGGCTGGCTACCCACCAACTACTGCGACGCGTACGAGCCCGACGACATGCGAAGCCTGCTCAAGGCCCTCCTC AACTTCTGGGATCTTCTGCGGAGCACCTCCATCAACGACAATGAGATTTTCAGGAATCAAGAGTTCATGAAGGGC ATCATTGCCGGCGTCCGCTTCCTTCTGGAACGCACCCATTGTCTCAGCAGGGAATCTGCCGTCGTCCTGCGCAGC GATCCGCTCCGCAAGTCTCGAAAGTCGCTCCTCTCGGAACTTTCGCTGCTGGTCAAGACGGCGAAGCGGCTGCAG GAAAGCCAGAAGCGCACGCTCGAGCCCGCGGAAGACGTCAACGACATCATCGACGAGATGATTCTGAAGGCATTC AAGATCGTCACCAAGGGCGTCCGCTTCTTGGACATACTCGACGAGGACCGACGATCCCGCGCCCCGGCCGCCGTT ACCGTCATGGCCACCGTCGCCGAGGAGTCGTGCGTGCCTCCCACACCACCCGCCGACCAGATGAGCTTTGACGAC AATCACGCACGCGGCCGGTCGGGCGATGTCAGTTCCCAAGACACGTCCGAGGACACTCGCGCGGCCAGCACCGTT GCGTCGGAATCGAGCGAGGCCTCGGGAGCACAAGTCAAGGCGACCCCTTGGGGCAGGCGCCTGTCGTCGCTCAAC GCACCGGTTCATCCCGGCGCCCCCCACGCTGGATCGGCTCAGAACCGGCTATCTCAAGGCAGCCAGTACCAAGCC AACCGCCTCTCGGGCTCCATGGCGCACCGCGTGTCGCTGGCCGGTCCTTCGCCCTTGTCCAGGCCCAATCACCTG GCGTCCGAACGGCTCAACCGAAGCCACGACAAGCTACTGTCGCATCTTGGCTCCTTCATCGGCAGGTTGCACCTG CACTCACATTCCCGACCTGAGCTTGCGCTCGCCATCAAGCTGTCTGCCGCGTCGGGCGGAGAGCTCTTGACCGTC ATCGACGGCGTCTGCGGATACAACAGCTCGAACCTCAACGCGCTCGGCCATGTCCGCACCGCCATGTTCGACCGC ATACAGGCCCTGGTCCACGCTGCATCCGACATTCTGTGTCACCCGACGACCGAGGAGGGCACGGACATGATTATG CCGTACGACAACAACCTGCTGCTCATGGCGGCTACGGGATGCGTCCGCGCCGCCGGCGAGTGCGTGGCCAAGGCC AAGGCGGCCATCGAGAGGGCCGGGGACTTCGAGTTTGAACTGGGGGACAACGCGCTGGGCTTGGACCTCGGCGTC CTGGACGCCGTCATGCAGGAACGGTCGAGAACGCCGTCAGTCGCGGATCGGTCCGACGTAAGCGTCGCCGAGTCT TCCTCCCACATCCCGGAGCAGCCGCCGGTTCCGAGGCCGCGCCGGCCGACCATGGGCGCGGTCGACAAGCCGCTT CCCCGCGTCCCCAAACTCAGCATCCCGACGGAGCAGCAGACCCGGAGGAGCAACTCGCCCGTTTCGTCTCGACCT GCGTCGGCAAACGACGACAATGCGTCGAGCGCGGCGTCTTCCGTCTCGTCTGTCCGTCCCGCGCCGCGCGCCATG CCAGGCCTGTTCAACCCGCCACATCCTGCCGATCTCATCCCGGCGGCCGATGCGGCGAGGAACGAGCCCGACCTG CAGGCCTCGCGGTTCGACGCCATTGCGGCCTCGAGCGCCGGCAGCAGTGCCACCTATCTGAGCCGAGACTCGGAG ACGAGCATCGTCTCGCAGACGTCGACCCGCGCCACGACGCCGGACCATGGACTCGCGCCGCGCAGCCAGCCATCC ATGTCGGAGCTGAGCGCGGCTGGCAGTTTCTCGCAGGCCGAAGAGGCCGATGACGTCGAGACGAGGCTCTTGGAG AGGACCTATGCGCACGAGCTCATGTTCAACAAGGAGGGCCAGGTCACCGGCGGCTCCCTGCCGGCGCTTGTGGAG CGGCTCACCACCCACGAGTCCACGCCGGACGCCGCTTTCGTCTCGACCTTTTACCTCACCTTCAGACTCTTCTGC ACGCCGATCAAGCTGACGGAAGCCCTCATCGACCGCTTCGACTACGTGGGTGAATCCCCCCACATGTCGGGGCCG GTCCGCCTCCGGGTATACAACGTCTTGAAGGGATGGCTCGAGTCTCACTGGAGGGACCGCACCGACCGGGGGGCG CTGCAGCTTATCATCCCGTTCGCGGAGGAGAAGCTGGGCGCCGCGATCCCCTCGGCCGGGAACCGCCTCCTTGAG CTGGCGAAGCGGGTGTCCGGAGACGGCCTACTGGTGCCCCGGCTGGTGTCGTCGATGGGCAAGACGAACACGGCC ATCGCTCAGTATGTGCCGGCGGACGCGCCCCTGCCGGCGCCGGCCATCTCCAAGAGCCAGCTGCACGCGCTCAAC GCCTTCCGGGCGGGAGTCAGCTCGCCCGCCATACTAGACTTCGATCCGCTCGAGGTGGCCCGTCAGCTGACGGTC AAGCAGATGGCCATCTTCTGCTCCATCCTGCCGGAGGAGCTGCTGGCGTCGCAGTGGATGAAGAACGGCGGAGCC GACGCGCCGCACGTCAAGGCCATGTCGTCGTTGTCGACGGACCTGTCCAACCTGGTGGCCGAGACGATCCTCCAG CAACACGAGATCAAGAAGCGCGCGGCCGTCATCAAGCAGTGGATCAAGATCGCCCACCACTGCCACGAGCTGCAC AACTACGACGGGCTGATGGCCATCATCTGCAGCCTCAACAGCAGCACCATCAGCCGTCTTCGCAAGACGTGGGAC GCCATCTCCCTCAAGCGGAAGGAGATGCTGCGAGCCATGCAGGACATCGTGGAGCCGTCGCAGAACCACAAGGTG CTCCGGACTCGGCTTCACGACCACGTCCCGCCCTGCCTGCCCTTCCTCGGCATGTACCTGACGGACCTGACGTTT GTGGACATCGGCAACCCCGCCACCAAGCAGATGTCTCTCGGCACCGAGGCCGACGAGACCGGCGCGGGCGGCCTG ACCGTCGTCAACTTCGACAAGCACTGCCGCACGGCCAAGATCATCGGCGAGCTGCAGCGGTTCCAGATCCCATAC CGGCTGATGGAGGTGCCCGACATGCAGGAGTGGCTGTCGGCCCAGATCCGGCGAGTGCGCAACAGCGACCAGGGC AACGTCCAGGTCACGTACTATCGCAAGAGCCTGCTCCTGGAGCCCCGCGAGACGCCGTCTCGCCGCGACCACGAA CCGCCGACGCCTATCTCCGGGTCGGGAGGCTCGCGCGCGGATCTGTTTGGGTGGATGTCGCGCGATCGAGGTGGC CAGACTCCCACTCCGGCACAGGGGTGA |
| Gene | >Hirsu2|2278 ATGACACCCCCCGCAACCCCCAATGGCTCCCAGGAGGACCTGTCGCCCGAGGTCCTCGACCCGCCCGTTTTCCAC AGCTTCCTGCGGGCCTTCTATCCATTCAGCCCCAGCGATGCCATGACCGAGTCGAGCGTGACGCTGCCGCTTGAC GAGGGAGACGTCGTCCTCGTCCACTCCGTCCACACGAATGGATGGGCCGACGGGACCCTGCTGGCAACGGGCGCC AGGGGCTGGCTACCCACCAACTACTGCGACGCGTACGAGCCCGACGACATGCGAAGCCTGCTCAAGGCCCTCCTC AACTTCTGGGATCTTCTGCGGAGCACCTCCATCAACGACAATGAGATTTTCAGGAATCAAGAGTTCATGAAGGGC ATCATTGCCGGCGTCCGCTTCCTTCTGGTATGTCCTTCCCCAAAACGCCCCCGATGCGCCGTGACTGTCGAGTAG AGCATGGCCCCCCTGACCCTTTCCCCTCGTTCTGTCGGGCACAGGAACGCACCCATTGTCTCAGCAGGGAATCTG CCGTCGTCCTGCGCAGCGATCCGCTCCGCAAGTCTCGAAAGTCGCTCCTCTCGGAACTTTCGCTGCTGGTCAAGA CGGCGAAGCGGCTGCAGGAAAGCCAGAAGCGCACGCTCGAGCCCGCGGAAGACGTCAACGACATCATCGACGAGA TGATTCTGAAGGCATTCAAGATCGTCACCAAGGGCGTCCGCTTCTTGGACATACTCGACGAGGACCGACGATCCC GCGCCCCGGCCGCCGTTACCGTCATGGCCACCGTCGCCGAGGAGTCGTGCGTGCCTCCCACACCACCCGCCGACC AGATGAGCTTTGACGACAATCACGCACGCGGCCGGTCGGGCGATGTCAGTTCCCAAGACACGTCCGAGGACACTC GCGCGGCCAGCACCGTTGCGTCGGAATCGAGCGAGGCCTCGGGAGCACAAGTCAAGGCGACCCCTTGGGGCAGGC GCCTGTCGTCGCTCAACGCACCGGTTCATCCCGGCGCCCCCCACGCTGGATCGGCTCAGAACCGGCTATCTCAAG GCAGCCAGTACCAAGCCAACCGCCTCTCGGGCTCCATGGCGCACCGCGTGTCGCTGGCCGGTCCTTCGCCCTTGT CCAGGCCCAATCACCTGGCGTCCGAACGGCTCAACCGAAGCCACGACAAGCTACTGTCGCATCTTGGCTCCTTCA TCGGCAGGTTGCACCTGCACTCACATTCCCGACCTGAGCTTGCGCTCGCCATCAAGCTGTCTGCCGCGTCGGGCG GAGAGCTCTTGACCGTCATCGACGGCGTCTGCGGATACAACAGCTCGAACCTCAACGCGCTCGGCCATGTCCGCA CCGCCATGTTCGACCGCATACAGGCCCTGGTCCACGCTGCATCCGACATTCTGTGTCACCCGACGACCGAGGAGG GCACGGACATGATTATGCCGTACGACAACAACCTGCTGCTCATGGCGGCTACGGGATGCGTCCGCGCCGCCGGCG AGTGCGTGGCCAAGGCCAAGGCGGCCATCGAGAGGGCCGGGGACTTCGAGTTTGAACTGGGGGACAACGCGCTGG GCTTGGACCTCGGCGTCCTGGACGCCGTCATGCAGGAACGGTCGAGAACGCCGTCAGTCGCGGATCGGTCCGACG TAAGCGTCGCCGAGTCTTCCTCCCACATCCCGGAGCAGCCGCCGGTTCCGAGGCCGCGCCGGCCGACCATGGGCG CGGTCGACAAGCCGCTTCCCCGCGTCCCCAAACTCAGCATCCCGACGGAGCAGCAGACCCGGAGGAGCAACTCGC CCGTTTCGTCTCGACCTGCGTCGGCAAACGACGACAATGCGTCGAGCGCGGCGTCTTCCGTCTCGTCTGTCCGTC CCGCGCCGCGCGCCATGCCAGGCCTGTTCAACCCGCCACATCCTGCCGATCTCATCCCGGCGGCCGATGCGGCGA GGAACGAGCCCGACCTGCAGGCCTCGCGGTTCGACGCCATTGCGGCCTCGAGCGCCGGCAGCAGTGCCACCTATC TGAGCCGAGACTCGGAGACGAGCATCGTCTCGCAGACGTCGACCCGCGCCACGACGCCGGACCATGGACTCGCGC CGCGCAGCCAGCCATCCATGTCGGAGCTGAGCGCGGCTGGCAGTTTCTCGCAGGCCGAAGAGGCCGATGACGTCG AGACGAGGCTCTTGGAGAGGACCTATGCGCACGAGCTCATGTTCAACAAGGAGGGCCAGGTCACCGGCGGCTCCC TGCCGGCGCTTGTGGAGCGGCTCACCACCCACGAGTCCACGCCGGACGCCGCTTTCGTCTCGACCTTTTACCTCA CCTTCAGACTCTTCTGCACGCCGATCAAGCTGACGGAAGCCCTCATCGACCGCTTCGACTACGTGGGTGAATCCC CCCACATGTCGGGGCCGGTCCGCCTCCGGGTATACAACGTCTTGAAGGGATGGCTCGAGTCTCACTGGAGGGACC GCACCGACCGGGGGGCGCTGCAGCTTATCATCCCGTTCGCGGAGGAGAAGCTGGGCGCCGCGATCCCCTCGGCCG GGAACCGCCTCCTTGAGCTGGCGAAGCGGGTGTCCGGAGACGGCCTACTGGTGCCCCGGCTGGTGTCGTCGATGG GCAAGACGAACACGGCCATCGCTCAGTATGTGCCGGCGGACGCGCCCCTGCCGGCGCCGGCCATCTCCAAGAGCC AGCTGCACGCGCTCAACGCCTTCCGGGCGGGAGTCAGCTCGCCCGCCATACTAGACTTCGATCCGCTCGAGGTGG CCCGTCAGCTGACGGTCAAGCAGATGGCCATCTTCTGCTCCATCCTGCCGGAGGAGCTGCTGGCGTCGCAGTGGA TGAAGAACGGCGGAGCCGACGCGCCGCACGTCAAGGCCATGTCGTCGTTGTCGACGGACCTGTCCAACCTGGTGG CCGAGACGATCCTCCAGCAACACGAGATCAAGAAGCGCGCGGCCGTCATCAAGCAGTGGATCAAGATCGCCCACC ACTGCCACGAGCTGCACAACTACGACGGGCTGATGGCCATCATCTGCAGCCTCAACAGCAGCACCATCAGCCGTC TTCGCAAGACGTGGGACGCCATCTCCCTCAAGCGGAAGGAGATGCTGCGAGCCATGCAGGACATCGTGGAGCCGT CGCAGAACCACAAGGTGCTCCGGACTCGGCTTCACGACCACGTCCCGCCCTGCCTGCCCTTCCTCGGCATGTACC TGACGGACCTGACGTTTGTGGACATCGGCAACCCCGCCACCAAGCAGATGTCTCTCGGCACCGAGGCCGACGAGA CCGGCGCGGGCGGCCTGACCGTCGTCAACTTCGACAAGCACTGCCGCACGGCCAAGATCATCGGCGAGCTGCAGC GGTTCCAGATCCCATACCGGCTGATGGAGGTGCCCGACATGCAGGAGTGGCTGTCGGCCCAGATCCGGCGAGTGC GCAACAGCGACCAGGGCAACGTCCAGGTCACGTACTATCGCAAGAGCCTGCTCCTGGAGCCCCGCGAGACGCCGT CTCGCCGCGACCACGAACCGCCGACGCCTATCTCCGGGTCGGGAGGCTCGCGCGCGGATCTGTTTGGGTGGATGT CGCGCGATCGAGGTGGCCAGACTCCCACTCCGGCACAGGGGTGA |