© 2023 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|11186 |
| Gene name | |
| Location | Contig_98:29503..32414 |
| Strand | + |
| Gene length (bp) | 2911 |
| Transcript length (bp) | 2643 |
| Coding sequence length (bp) | 2643 |
| Protein length (aa) | 881 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF14765 | PS-DH | Polyketide synthase dehydratase | 7.0E-39 | 2 | 273 |
| PF08242 | Methyltransf_12 | Methyltransferase domain | 1.8E-16 | 453 | 552 |
| PF13649 | Methyltransf_25 | Methyltransferase domain | 1.6E-11 | 451 | 550 |
| PF08241 | Methyltransf_11 | Methyltransferase domain | 2.9E-10 | 453 | 553 |
| PF13489 | Methyltransf_23 | Methyltransferase domain | 5.1E-09 | 444 | 604 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|A1CLY8|CCSA_ASPCL | Polyketide synthase-nonribosomal peptide synthetase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=ccsA PE=3 SV=1 | 1 | 837 | 3.0E-133 |
| sp|Q0C8M3|LNKS_ASPTN | Lovastatin nonaketide synthase OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=lovB PE=3 SV=2 | 3 | 845 | 3.0E-94 |
| sp|Q9Y8A5|LNKS_ASPTE | Lovastatin nonaketide synthase OS=Aspergillus terreus GN=lovB PE=1 SV=1 | 3 | 845 | 5.0E-94 |
| sp|Q4WAZ9|NRP14_ASPFU | Nonribosomal peptide synthetase 14 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=NRPS14 PE=2 SV=2 | 1 | 841 | 3.0E-83 |
| sp|Q9Y7D5|LOVF_ASPTE | Lovastatin diketide synthase LovF OS=Aspergillus terreus GN=lovF PE=1 SV=1 | 1 | 770 | 1.0E-50 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|A1CLY8|CCSA_ASPCL | Polyketide synthase-nonribosomal peptide synthetase OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) GN=ccsA PE=3 SV=1 | 1 | 837 | 3.0E-133 |
| sp|Q0C8M3|LNKS_ASPTN | Lovastatin nonaketide synthase OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=lovB PE=3 SV=2 | 3 | 845 | 3.0E-94 |
| sp|Q9Y8A5|LNKS_ASPTE | Lovastatin nonaketide synthase OS=Aspergillus terreus GN=lovB PE=1 SV=1 | 3 | 845 | 5.0E-94 |
| sp|Q4WAZ9|NRP14_ASPFU | Nonribosomal peptide synthetase 14 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN=NRPS14 PE=2 SV=2 | 1 | 841 | 3.0E-83 |
| sp|Q9Y7D5|LOVF_ASPTE | Lovastatin diketide synthase LovF OS=Aspergillus terreus GN=lovF PE=1 SV=1 | 1 | 770 | 1.0E-50 |
| sp|O31784|PKSR_BACSU | Polyketide synthase PksR OS=Bacillus subtilis (strain 168) GN=pksR PE=1 SV=2 | 448 | 602 | 1.0E-16 |
| sp|Q55E72|PKS1_DICDI | Probable polyketide synthase 1 OS=Dictyostelium discoideum GN=stlA PE=1 SV=1 | 342 | 832 | 2.0E-15 |
| sp|P40872|PKSM_BACSU | Polyketide synthase PksM OS=Bacillus subtilis (strain 168) GN=pksM PE=1 SV=4 | 474 | 605 | 1.0E-12 |
| sp|Q559A9|PKS13_DICDI | Probable polyketide synthase 13 OS=Dictyostelium discoideum GN=pks13 PE=3 SV=1 | 410 | 626 | 2.0E-11 |
| sp|Q54D44|PKS42_DICDI | Probable polyketide synthase 42 OS=Dictyostelium discoideum GN=pks42 PE=3 SV=2 | 409 | 618 | 8.0E-10 |
| sp|Q54FQ3|PKS29_DICDI | Probable polyketide synthase 29 OS=Dictyostelium discoideum GN=pks29 PE=3 SV=1 | 435 | 615 | 2.0E-09 |
| sp|Q54IX3|PKS26_DICDI | Probable polyketide synthase 26 OS=Dictyostelium discoideum GN=pks26 PE=3 SV=1 | 410 | 841 | 2.0E-09 |
| sp|Q54FN7|PKS33_DICDI | Probable polyketide synthase 33 OS=Dictyostelium discoideum GN=pks33 PE=3 SV=2 | 418 | 616 | 2.0E-09 |
| sp|Q54FQ1|PKS31_DICDI | Probable polyketide synthase 31 OS=Dictyostelium discoideum GN=pks31 PE=3 SV=1 | 410 | 615 | 6.0E-09 |
| sp|Q54FQ2|PKS30_DICDI | Probable polyketide synthase 30 OS=Dictyostelium discoideum GN=pks30 PE=3 SV=1 | 410 | 615 | 9.0E-09 |
| sp|Q54FN2|PKS34_DICDI | Probable polyketide synthase 34 OS=Dictyostelium discoideum GN=pks34 PE=3 SV=1 | 410 | 615 | 1.0E-08 |
| sp|Q54FP8|PKS32_DICDI | Probable polyketide synthase 32 OS=Dictyostelium discoideum GN=pks32 PE=3 SV=1 | 410 | 615 | 1.0E-08 |
| sp|Q54G30|PKS27_DICDI | Probable polyketide synthase 27 OS=Dictyostelium discoideum GN=pks27 PE=3 SV=1 | 450 | 615 | 2.0E-08 |
| sp|Q54FC8|PKS39_DICDI | Probable polyketide synthase 39 OS=Dictyostelium discoideum GN=pks39 PE=3 SV=1 | 435 | 615 | 2.0E-08 |
| sp|Q54ED6|PKS41_DICDI | Probable polyketide synthase 41 OS=Dictyostelium discoideum GN=pks41 PE=3 SV=1 | 410 | 603 | 1.0E-07 |
| sp|Q54FD2|PKS38_DICDI | Probable polyketide synthase 38 OS=Dictyostelium discoideum GN=pks38 PE=3 SV=1 | 435 | 599 | 1.0E-07 |
| sp|Q54ED7|PKS40_DICDI | Probable polyketide synthase 40 OS=Dictyostelium discoideum GN=pks40 PE=3 SV=1 | 410 | 603 | 1.0E-07 |
| sp|B0G170|PKS28_DICDI | Probable polyketide synthase 28 OS=Dictyostelium discoideum GN=pks28 PE=3 SV=1 | 410 | 615 | 2.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0008168 | methyltransferase activity | Yes |
| GO:0016740 | transferase activity | No |
| GO:0003824 | catalytic activity | No |
| GO:0003674 | molecular_function | No |
| GO:0016741 | transferase activity, transferring one-carbon groups | No |
| Localizations | Signals | Cytoplasm | Nucleus | Extracellular | Cell membrane | Mitochondrion | Plastid | Endoplasmic reticulum | Lysosome vacuole | Golgi apparatus | Peroxisome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cytoplasm | Nuclear localization signal | 0.6202 | 0.4343 | 0.04 | 0.0891 | 0.1096 | 0.0417 | 0.0141 | 0.039 | 0.1321 | 0.0062 |
| Gene cluster ID | Type of secondary metabolism gene |
|---|---|
| Cluster 44 | (None) |
| Orthofinder run ID | 4 |
| Orthogroup | 6951 |
| Change Orthofinder run |
| Species | Protein ID |
|---|---|
| Ophiocordyceps subramaniannii | Hirsu2|11186 (this protein) |
| Ophiocordyceps subramaniannii | Hirsu2|3121 |
| Ophiocordyceps subramaniannii | Hirsu2|3277 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
Download genbank file of locus (reverse complement)
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|11186 MPWAEGHKFQGQVLFPGAGYMSLAVEATKAFVQDRPVKLLEVRDMNIPKALVIGEDDGVELLFTIRSKILPSSVG DDSTLEAEFVAYSCSDKRVLDKTCDGRLFVHLGRAQPGDLPPNPVSRAELTPLSTERFYHAVSRIDLDYDGPFRA LSSISRSWGQAKATASWDKGELDIGCALHPALLDNAFQTGLATFVSTAENAMGGPFLPVGIRRALIDPNFDYGDS SGTTNVDIGAVMTEASPTVVEVDIGVCADNACGVQVDGLILKMIAEPEAADDRNLFAKTIWNLDCAYSLTFSPPV RDDVGELAAMSDVYERLTLFYMQNLLREVPPAEFDSAKWHHRELLRFIHATSETVRGGRHPVLQKAWLDDNRDTI SRIVERYPGNINIEMLTAVGENLPSVVRGQSGMIEHMLQGDLLGRLYRESSGLVACNQHIAQLMRQISHKHPRTK IIEIGAGTGGTTMSALDALGDAYSSYTCTDISASFFNGLSDRLPQRHAGKVDFKVYDVEKTPAAEDIGSYSVVLA ANVLHATRKLSETVRNARALLRPGGYLIAVEVTGQMLRETGLMGGLEGWWLGAGEGRSMGPGVSPRDWDNILEQN GFSGIDCIFHDNPNVSRHSCSVFASQAVDDKFKLLRDPLANIDLIPESRVLIVGGRTLPVSKLVRRAEKMLSQWS SDITTCSSIDELDAAQIHPGTFVLCLSDLDRPFFAEPPTAKQLDNLQEMLGSAKQVLWVTCGRLLDDPYSNMMVG VGRALAVELPHVNIHYLDFDRQQSWDVEILLREMLRMMASPTSKADTHGMLWVEEPEIVVRKDEILVPRIMQDTA ANESLNAKRRRISKSVDSTRRITVVKDSISLRPVLVADGPLDIPVGFMAFDPMAV* |
| Coding | >Hirsu2|11186 ATGCCCTGGGCCGAGGGACACAAGTTCCAGGGTCAGGTCCTGTTTCCAGGGGCCGGCTACATGAGTCTCGCAGTG GAGGCAACCAAGGCCTTCGTTCAGGACCGACCCGTCAAACTGCTTGAAGTTCGGGATATGAACATCCCAAAGGCG CTGGTGATCGGCGAGGACGATGGCGTCGAGCTTCTATTCACCATTCGCAGCAAGATCCTTCCCTCCAGCGTAGGA GACGACTCTACTCTGGAGGCCGAGTTTGTGGCGTACAGCTGCAGCGACAAGCGAGTACTGGATAAGACTTGCGAC GGCCGCCTCTTCGTCCACCTCGGCCGAGCGCAGCCCGGAGACCTGCCGCCCAACCCAGTCTCCCGGGCAGAGCTC ACGCCGCTCAGCACCGAACGCTTCTATCATGCCGTTTCGAGGATCGACCTCGACTATGATGGCCCCTTTCGTGCG CTTAGCTCGATCAGCAGGTCATGGGGTCAGGCCAAGGCAACTGCGTCGTGGGATAAGGGAGAGCTCGACATTGGA TGCGCGCTGCATCCCGCTCTTCTGGATAATGCCTTCCAGACGGGGCTGGCGACGTTTGTATCCACAGCCGAAAAC GCCATGGGCGGGCCGTTTCTTCCTGTTGGCATCCGACGGGCACTCATTGACCCAAACTTCGACTATGGGGATTCG TCGGGCACGACGAACGTTGATATAGGAGCGGTCATGACGGAAGCCAGCCCGACCGTGGTTGAAGTAGACATCGGT GTGTGCGCCGACAACGCCTGCGGAGTCCAGGTAGACGGACTGATTCTGAAGATGATCGCGGAGCCAGAAGCAGCT GACGACCGGAATCTGTTCGCGAAAACTATCTGGAACCTCGACTGCGCATACTCTCTGACTTTCTCGCCCCCTGTC CGGGACGACGTGGGCGAGCTGGCCGCGATGTCCGACGTGTATGAGCGGCTTACGCTGTTCTACATGCAAAATCTG CTTCGCGAGGTTCCCCCAGCGGAATTTGATTCCGCAAAGTGGCACCACAGAGAGCTGTTGCGCTTCATTCATGCC ACCTCGGAGACGGTGCGAGGAGGTCGTCATCCTGTCTTGCAGAAGGCATGGCTGGATGACAACCGTGACACGATA TCACGGATTGTCGAGCGCTACCCCGGTAACATAAACATAGAAATGCTCACAGCTGTCGGAGAGAACCTGCCCTCG GTGGTGCGAGGGCAGTCTGGGATGATCGAGCACATGCTACAAGGCGACCTGCTCGGCCGCTTGTACAGAGAAAGC AGTGGACTTGTGGCCTGTAACCAGCATATTGCTCAACTTATGCGACAGATAAGCCACAAGCATCCCCGGACCAAG ATCATTGAGATCGGCGCCGGGACTGGAGGCACGACCATGAGCGCCCTGGACGCCCTTGGCGATGCCTATTCGTCG TACACCTGCACCGACATCTCAGCAAGCTTCTTCAACGGGCTTTCAGATAGGCTGCCACAGAGACACGCCGGAAAA GTCGACTTCAAAGTGTATGACGTCGAAAAAACCCCGGCCGCCGAAGATATTGGGTCCTATTCAGTCGTTCTGGCG GCCAATGTCTTACACGCCACCCGGAAGCTTTCAGAGACTGTTCGTAACGCAAGAGCTCTCCTGAGACCCGGCGGT TACCTGATCGCGGTCGAGGTCACCGGCCAAATGCTGAGAGAAACCGGCCTCATGGGAGGTCTGGAGGGCTGGTGG CTCGGTGCGGGCGAGGGAAGGTCAATGGGCCCCGGCGTCAGCCCCCGAGACTGGGACAACATCCTCGAACAAAAC GGGTTTTCTGGTATCGACTGCATTTTCCACGACAACCCCAACGTCAGCAGACATAGCTGTTCCGTGTTTGCTTCG CAGGCTGTAGACGACAAGTTCAAACTGTTACGCGATCCGCTTGCCAACATCGACCTCATCCCGGAGAGCCGCGTT CTCATCGTTGGCGGGCGGACTCTGCCAGTGTCCAAGCTCGTCCGACGCGCAGAGAAGATGCTGTCTCAGTGGTCG TCCGACATCACTACCTGCAGCAGCATAGACGAGCTAGACGCGGCGCAGATCCACCCCGGAACCTTTGTCTTATGT CTCTCGGACCTTGACCGACCGTTCTTTGCCGAGCCGCCGACGGCCAAGCAGCTGGACAACCTCCAGGAGATGTTG GGCAGCGCCAAACAAGTCTTATGGGTTACATGCGGCAGATTGCTGGACGATCCCTACTCTAATATGATGGTCGGC GTTGGACGGGCGTTGGCCGTAGAGCTGCCCCATGTCAACATTCATTACCTGGACTTCGACCGGCAGCAGTCCTGG GACGTCGAGATCTTACTCCGTGAAATGCTGCGGATGATGGCCTCTCCGACCTCCAAGGCCGATACGCACGGCATG CTTTGGGTCGAGGAGCCCGAGATCGTTGTGCGCAAGGACGAGATCCTGGTGCCGCGCATCATGCAGGATACAGCA GCAAATGAGAGCCTCAACGCCAAGCGTCGTCGGATAAGCAAGTCGGTCGACTCGACGAGGAGAATCACAGTCGTC AAGGACAGCATCTCCTTAAGGCCCGTCCTGGTCGCGGACGGCCCCCTTGATATCCCCGTCGGTTTCATGGCGTTT GATCCGATGGCCGTCTAG |
| Transcript | >Hirsu2|11186 ATGCCCTGGGCCGAGGGACACAAGTTCCAGGGTCAGGTCCTGTTTCCAGGGGCCGGCTACATGAGTCTCGCAGTG GAGGCAACCAAGGCCTTCGTTCAGGACCGACCCGTCAAACTGCTTGAAGTTCGGGATATGAACATCCCAAAGGCG CTGGTGATCGGCGAGGACGATGGCGTCGAGCTTCTATTCACCATTCGCAGCAAGATCCTTCCCTCCAGCGTAGGA GACGACTCTACTCTGGAGGCCGAGTTTGTGGCGTACAGCTGCAGCGACAAGCGAGTACTGGATAAGACTTGCGAC GGCCGCCTCTTCGTCCACCTCGGCCGAGCGCAGCCCGGAGACCTGCCGCCCAACCCAGTCTCCCGGGCAGAGCTC ACGCCGCTCAGCACCGAACGCTTCTATCATGCCGTTTCGAGGATCGACCTCGACTATGATGGCCCCTTTCGTGCG CTTAGCTCGATCAGCAGGTCATGGGGTCAGGCCAAGGCAACTGCGTCGTGGGATAAGGGAGAGCTCGACATTGGA TGCGCGCTGCATCCCGCTCTTCTGGATAATGCCTTCCAGACGGGGCTGGCGACGTTTGTATCCACAGCCGAAAAC GCCATGGGCGGGCCGTTTCTTCCTGTTGGCATCCGACGGGCACTCATTGACCCAAACTTCGACTATGGGGATTCG TCGGGCACGACGAACGTTGATATAGGAGCGGTCATGACGGAAGCCAGCCCGACCGTGGTTGAAGTAGACATCGGT GTGTGCGCCGACAACGCCTGCGGAGTCCAGGTAGACGGACTGATTCTGAAGATGATCGCGGAGCCAGAAGCAGCT GACGACCGGAATCTGTTCGCGAAAACTATCTGGAACCTCGACTGCGCATACTCTCTGACTTTCTCGCCCCCTGTC CGGGACGACGTGGGCGAGCTGGCCGCGATGTCCGACGTGTATGAGCGGCTTACGCTGTTCTACATGCAAAATCTG CTTCGCGAGGTTCCCCCAGCGGAATTTGATTCCGCAAAGTGGCACCACAGAGAGCTGTTGCGCTTCATTCATGCC ACCTCGGAGACGGTGCGAGGAGGTCGTCATCCTGTCTTGCAGAAGGCATGGCTGGATGACAACCGTGACACGATA TCACGGATTGTCGAGCGCTACCCCGGTAACATAAACATAGAAATGCTCACAGCTGTCGGAGAGAACCTGCCCTCG GTGGTGCGAGGGCAGTCTGGGATGATCGAGCACATGCTACAAGGCGACCTGCTCGGCCGCTTGTACAGAGAAAGC AGTGGACTTGTGGCCTGTAACCAGCATATTGCTCAACTTATGCGACAGATAAGCCACAAGCATCCCCGGACCAAG ATCATTGAGATCGGCGCCGGGACTGGAGGCACGACCATGAGCGCCCTGGACGCCCTTGGCGATGCCTATTCGTCG TACACCTGCACCGACATCTCAGCAAGCTTCTTCAACGGGCTTTCAGATAGGCTGCCACAGAGACACGCCGGAAAA GTCGACTTCAAAGTGTATGACGTCGAAAAAACCCCGGCCGCCGAAGATATTGGGTCCTATTCAGTCGTTCTGGCG GCCAATGTCTTACACGCCACCCGGAAGCTTTCAGAGACTGTTCGTAACGCAAGAGCTCTCCTGAGACCCGGCGGT TACCTGATCGCGGTCGAGGTCACCGGCCAAATGCTGAGAGAAACCGGCCTCATGGGAGGTCTGGAGGGCTGGTGG CTCGGTGCGGGCGAGGGAAGGTCAATGGGCCCCGGCGTCAGCCCCCGAGACTGGGACAACATCCTCGAACAAAAC GGGTTTTCTGGTATCGACTGCATTTTCCACGACAACCCCAACGTCAGCAGACATAGCTGTTCCGTGTTTGCTTCG CAGGCTGTAGACGACAAGTTCAAACTGTTACGCGATCCGCTTGCCAACATCGACCTCATCCCGGAGAGCCGCGTT CTCATCGTTGGCGGGCGGACTCTGCCAGTGTCCAAGCTCGTCCGACGCGCAGAGAAGATGCTGTCTCAGTGGTCG TCCGACATCACTACCTGCAGCAGCATAGACGAGCTAGACGCGGCGCAGATCCACCCCGGAACCTTTGTCTTATGT CTCTCGGACCTTGACCGACCGTTCTTTGCCGAGCCGCCGACGGCCAAGCAGCTGGACAACCTCCAGGAGATGTTG GGCAGCGCCAAACAAGTCTTATGGGTTACATGCGGCAGATTGCTGGACGATCCCTACTCTAATATGATGGTCGGC GTTGGACGGGCGTTGGCCGTAGAGCTGCCCCATGTCAACATTCATTACCTGGACTTCGACCGGCAGCAGTCCTGG GACGTCGAGATCTTACTCCGTGAAATGCTGCGGATGATGGCCTCTCCGACCTCCAAGGCCGATACGCACGGCATG CTTTGGGTCGAGGAGCCCGAGATCGTTGTGCGCAAGGACGAGATCCTGGTGCCGCGCATCATGCAGGATACAGCA GCAAATGAGAGCCTCAACGCCAAGCGTCGTCGGATAAGCAAGTCGGTCGACTCGACGAGGAGAATCACAGTCGTC AAGGACAGCATCTCCTTAAGGCCCGTCCTGGTCGCGGACGGCCCCCTTGATATCCCCGTCGGTTTCATGGCGTTT GATCCGATGGCCGTCTAG |
| Gene | >Hirsu2|11186 ATGCCCTGGGCCGAGGGACACAAGTTCCAGGGTCAGGTCCTGTTTCCAGGGGCCGGCTACATGAGTCTCGCAGTG GAGGCAACCAAGGCCTTCGTTCAGGACCGACCCGTCAAACTGCTTGAAGTTCGGGATATGAACATCCCAAAGGCG CTGGTGATCGGCGAGGACGATGGCGTCGAGCTTCTATTCACCATTCGCAGCAAGATCCTTCCCTCCAGCGTAGGA GACGACTCTACTCTGGAGGCCGAGTTTGTGGCGTACAGCTGCAGCGACAAGCGAGTACTGGATAAGACTTGCGAC GGCCGCCTCTTCGTCCACCTCGGCCGAGCGCAGCCCGGAGACCTGCCGCCCAACCCAGTCTCCCGGGCAGAGCTC ACGCCGCTCAGCACCGAACGCTTCTATCATGCCGTTTCGAGGATCGACCTCGACTATGATGGCCCCTTTCGTGCG CTTAGCTCGATCAGCAGGTCATGGGGTCAGGCCAAGGCAACTGCGTCGTGGGATAAGGGAGAGCTCGACATTGGA TGCGCGCTGCATCCCGCTCTTCTGGATAATGCCTTCCAGACGGGGCTGGCGACGTTTGTATCCACAGCCGAAAAC GCCATGGGCGGGCCGTTTCTTCCTGTTGGCATCCGACGGGCACTCATTGACCCAAACTTCGACTATGGGGATTCG TCGGGCACGACGAACGTTGATATAGGAGCGGTCATGACGGAAGCCAGCCCGACCGTGGTTGAAGTAGACATCGGT GTGTGCGCCGACAACGCCTGCGGAGTCCAGGTAGACGGACTGATTCTGAAGATGATCGCGGAGCCAGAAGCAGCT GACGACCGGAATCTGTTCGCGAAAACTATCTGGAACCTCGACTGCGCATACTCTCTGACTTTCTCGCCCCCTGTC CGGGACGACGTGGGCGAGCTGGCCGCGATGTCCGACGTGTATGAGCGGCTTACGCTGTTCTACATGCAAAATCTG CTTCGCGAGGTTCCCCCAGCGGAATTTGATTCCGCAAAGTGGCACCACAGAGAGCTGTTGCGCTTCATTCATGCC ACCTCGGAGACGGTGCGAGGAGGTCGTCATCCTGTCTTGCAGAAGGCATGGCTGGATGACAACCGTGACACGATA TCACGGATTGTCGAGCGCTACCCCGGTAACATAAACATAGAAATGCTCACAGCTGTCGGAGAGAACCTGCCCTCG GTGGTGCGAGGGCAGTCTGGGATGATCGAGCACATGCTACAAGGCGACCTGCTCGGCCGCTTGTACAGAGAAAGC AGTGGACTTGTGGCCTGTAACCAGCATATTGCTCAACTTATGCGACAGATAAGCCACAAGCATCCCCGGACCAAG ATCATTGAGATCGGCGCCGGGACTGGAGGCACGACCATGAGCGCCCTGGACGCCCTTGGCGATGCCTATTCGTCG TACACCTGCACCGACATCTCAGCAAGCTTCTTCAACGGGCTTTCAGATAGGCTGCCACAGAGACACGCCGGAAAA GTCGACTTCAAAGTGTATGACGTCGAAAAAACCCCGGCCGCCGAAGATATTGGGTCCTATTCAGTCGTTCTGGCG GCCAATGTCTTACACGCCACCCGGAAGCTTTCAGAGACTGTTCGTAACGCAAGAGCTCTCCTGAGACCCGGCGGT TACCTGATCGCGGTCGAGGTCACCGGCCAAATGCTGAGAGAAACCGGCCTCATGGGAGGTCTGGAGGGCTGGTGG CTCGGTGCGGGCGAGGGAAGGTCAATGGGCCCCGGCGTCAGCCCCCGAGACTGGGACAACATCCTCGAACAAAAC GGGTTTTCTGGTATCGACTGCATTTTCCACGACAACCCCAACGTCAGCAGACATAGCTGTTCCGTGTTTGCTTCG CAGGCTGTAGACGACAAGTTCAAACTGTTACGCGATCCGCTTGCCAACATCGACCTCATCCCGGAGAGCCGCGTT CTCATCGTTGGCGGGCGGACTCTGCCAGTGTCCAAGCTCGTCCGACGCGCAGAGAAGATGCTGTCTCAGTGGTCG TCCGACATCACTACCTGCAGCAGCATAGACGAGCTAGACGCGGCGCAGATCCACCCCGGAACCTTTGTCTTATGT CTCTCGGACCTTGACCGACCGTTCTTTGCCGAGCCGCCGACGGCCAAGCAGCTGGACAACCTCCAGGAGATGTTG GGCAGCGCCAAACAAGTCTTATGGGTTACATGCGGCAGATTGCTGGACGATCCCTACTCTAATATGATGGTCGGC GTTGGACGGGCGTTGGCCGTAGAGCTGCCCCATGTCAACATTCATTACCTGGACTTCGACCGGCAGCAGTCCTGG GACGTCGAGATCTTACTCCGTGAAATGCTGCGGATGATGGCCTCTCCGACCTCCAAGGCCGATACGCACGGCATG CTTTGGGTCGAGGAGCCCGAGATCGTTGTGCGCAAGGACGAGATCCTGGTGCCGCGCATCATGCAGGATACAGCA GCAAATGAGAGCCTCAACGCCAAGCGTCGTCGGATAAGCAAGTCGGTCGACTCGACGAGGAGAATCACAGTCGTC AAGGACAGCATCTCCTTAAGGCCCGTCCTGGTCGCGGACGGCCCCCTTGATATCCCCGTCGGTTTCATGGCGTTT GATGTAAGACTGTCAGTGGCATTACACGCCGACGGAGAAGCACCTTGTTTCTTGAACTTTGGGCATTTTCATGGC TCAAGCCAGTCTGCTGCGTTTGCCCTGTCCGAAGTCAACTCTTCCACCGTGGTCGTGCATGCAGATTCCCTGTTC AGCCCCTCCAACTCGCAAGGCTGCAACGCAGAGACTCTCATGGGCATGGCACGCTCCATGATCGCTGCGCAAGTT CTTCTTGGCTTCCCGAGCCAAGGGACAACTCTCGTGTGCGGCATAGCCGATGGCCGTCTAG |