© 2022 - Robin Ohm - Utrecht University - The Netherlands
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| Protein ID | Hirsu2|10299 |
| Gene name | |
| Location | Contig_819:8203..10649 |
| Strand | - |
| Gene length (bp) | 2446 |
| Transcript length (bp) | 1608 |
| Coding sequence length (bp) | 1608 |
| Protein length (aa) | 536 |
| PFAM Domain ID | Short name | Long name | E-value | Start | End |
|---|---|---|---|---|---|
| PF07690 | MFS_1 | Major Facilitator Superfamily | 2.3E-38 | 100 | 486 |
| PF00083 | Sugar_tr | Sugar (and other) transporter | 1.4E-11 | 106 | 290 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P38776|YHK8_YEAST | Probable drug/proton antiporter YHK8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHK8 PE=1 SV=1 | 64 | 533 | 7.0E-124 |
| sp|Q10084|MFS2_SCHPO | Uncharacterized transporter mfs2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mfs2 PE=3 SV=1 | 1 | 535 | 1.0E-88 |
| sp|O59814|YCT4_SCHPO | Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC794.04c PE=3 SV=1 | 4 | 535 | 1.0E-87 |
| sp|O59699|YN42_SCHPO | Uncharacterized transporter C36.02c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC36.02c PE=3 SV=1 | 88 | 535 | 3.0E-83 |
| sp|P32071|CYHR_CANMA | Cycloheximide resistance protein OS=Candida maltosa GN=CYHR PE=3 SV=1 | 15 | 533 | 2.0E-82 |
| Swissprot ID | Swissprot Description | Start | End | E-value |
|---|---|---|---|---|
| sp|P38776|YHK8_YEAST | Probable drug/proton antiporter YHK8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHK8 PE=1 SV=1 | 64 | 533 | 7.0E-124 |
| sp|Q10084|MFS2_SCHPO | Uncharacterized transporter mfs2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mfs2 PE=3 SV=1 | 1 | 535 | 1.0E-88 |
| sp|O59814|YCT4_SCHPO | Uncharacterized transporter C794.04c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC794.04c PE=3 SV=1 | 4 | 535 | 1.0E-87 |
| sp|O59699|YN42_SCHPO | Uncharacterized transporter C36.02c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC36.02c PE=3 SV=1 | 88 | 535 | 3.0E-83 |
| sp|P32071|CYHR_CANMA | Cycloheximide resistance protein OS=Candida maltosa GN=CYHR PE=3 SV=1 | 15 | 533 | 2.0E-82 |
| sp|O74829|YN2F_SCHPO | Uncharacterized MFS-type transporter C530.15c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC530.15c PE=1 SV=2 | 61 | 531 | 9.0E-82 |
| sp|Q9Y7S4|YQO5_SCHPO | Uncharacterized transporter C569.05c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC569.05c PE=3 SV=1 | 13 | 533 | 1.0E-81 |
| sp|O59738|YN22_SCHPO | Uncharacterized transporter C530.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC530.02 PE=3 SV=1 | 64 | 535 | 8.0E-81 |
| sp|Q7Z9I0|YHA8_SCHPO | Uncharacterized MFS-type transporter C409.08 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC409.08 PE=3 SV=1 | 61 | 533 | 2.0E-80 |
| sp|P38124|FLR1_YEAST | Fluconazole resistance protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FLR1 PE=1 SV=1 | 61 | 535 | 6.0E-80 |
| sp|Q5ABU7|MDR1_CANAL | Multidrug resistance protein 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MDR1 PE=1 SV=1 | 69 | 534 | 5.0E-79 |
| sp|P28873|BMRP_CANAX | Benomyl/methotrexate resistance protein OS=Candida albicans GN=MDR1 PE=3 SV=1 | 69 | 534 | 5.0E-79 |
| sp|O59700|YN43_SCHPO | Uncharacterized transporter C36.03c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC36.03c PE=3 SV=1 | 10 | 531 | 2.0E-77 |
| sp|O94528|CAF5_SCHPO | Caffeine resistance protein 5 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=caf5 PE=3 SV=1 | 40 | 534 | 5.0E-77 |
| sp|Q10487|MFS1_SCHPO | Transporter mfs1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mfs1 PE=3 SV=1 | 69 | 533 | 2.0E-75 |
| sp|Q07824|TPO1_YEAST | Polyamine transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO1 PE=1 SV=1 | 63 | 533 | 8.0E-75 |
| sp|O59698|YN41_SCHPO | Uncharacterized transporter C36.01c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC36.01c PE=1 SV=1 | 6 | 535 | 8.0E-74 |
| sp|P53283|TPO2_YEAST | Polyamine transporter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO2 PE=1 SV=1 | 77 | 529 | 2.0E-72 |
| sp|Q06451|TPO3_YEAST | Polyamine transporter 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO3 PE=1 SV=1 | 51 | 529 | 2.0E-72 |
| sp|Q12256|TPO4_YEAST | Polyamine transporter 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TPO4 PE=1 SV=1 | 65 | 533 | 8.0E-72 |
| sp|Q9USN4|YJA1_SCHPO | Uncharacterized transporter C1529.01 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC1529.01 PE=3 SV=2 | 63 | 530 | 3.0E-71 |
| sp|Q9P3V5|YI45_SCHPO | Uncharacterized transporter C1348.05 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC1348.05 PE=3 SV=1 | 77 | 527 | 1.0E-67 |
| sp|Q9P3E8|YLZ2_SCHPO | Uncharacterized transporter C750.02c/PB2B2.16c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC750.02c PE=3 SV=1 | 77 | 527 | 8.0E-67 |
| sp|O43081|YHS6_SCHPO | Uncharacterized MFS-type transporter C947.06c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC947.06c PE=3 SV=1 | 24 | 534 | 7.0E-66 |
| sp|Q9HDX4|MFC1_SCHPO | Uncharacterized transporter mfc1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mfc1 PE=3 SV=2 | 106 | 532 | 9.0E-62 |
| sp|P33532|BSU1_SCHPO | Vitamin B6 transporter bsu1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=bsu1 PE=3 SV=2 | 49 | 530 | 1.0E-45 |
| sp|O59833|YCUD_SCHPO | Uncharacterized transporter C965.13 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC965.13 PE=3 SV=1 | 24 | 533 | 4.0E-41 |
| sp|O74899|YQEH_SCHPO | Uncharacterized transporter C576.17c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC576.17c PE=1 SV=1 | 25 | 535 | 4.0E-35 |
| sp|Q59XM0|QDR3_CANAL | MFS antiporter QDR3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=QDR3 PE=2 SV=1 | 89 | 289 | 4.0E-25 |
| sp|G2TRN8|YI74_SCHPO | Putative uncharacterized transporter C977.04 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC977.04 PE=5 SV=1 | 378 | 527 | 2.0E-23 |
| sp|P38125|DTR1_YEAST | Dityrosine transporter 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DTR1 PE=1 SV=1 | 106 | 513 | 1.0E-18 |
| sp|P40474|QDR2_YEAST | Quinidine resistance protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR2 PE=1 SV=1 | 140 | 526 | 7.0E-18 |
| sp|P40475|QDR1_YEAST | Quinidine resistance protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR1 PE=1 SV=1 | 26 | 533 | 5.0E-17 |
| sp|P53943|AQR1_YEAST | Probable transporter AQR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AQR1 PE=1 SV=1 | 84 | 485 | 4.0E-16 |
| sp|P53389|HOL1_YEAST | Protein HOL1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOL1 PE=1 SV=1 | 78 | 308 | 3.0E-15 |
| sp|P38227|QDR3_YEAST | Quinidine resistance protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR3 PE=1 SV=2 | 89 | 269 | 4.0E-15 |
| sp|P45123|BCR_HAEIN | Bicyclomycin resistance protein homolog OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=bcr PE=3 SV=1 | 132 | 271 | 1.0E-12 |
| sp|P38227|QDR3_YEAST | Quinidine resistance protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=QDR3 PE=1 SV=2 | 387 | 534 | 1.0E-11 |
| sp|Q59YT1|QDR2_CANAL | MFS antiporter QDR2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=QDR2 PE=3 SV=1 | 75 | 483 | 1.0E-11 |
| sp|P28246|BCR_ECOLI | Bicyclomycin resistance protein OS=Escherichia coli (strain K12) GN=bcr PE=1 SV=4 | 92 | 288 | 2.0E-11 |
| sp|Q59XM0|QDR3_CANAL | MFS antiporter QDR3 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=QDR3 PE=2 SV=1 | 301 | 497 | 9.0E-09 |
| sp|O94343|YHMA_SCHPO | Uncharacterized MFS-type transporter C1271.10c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC1271.10c PE=1 SV=1 | 34 | 269 | 2.0E-08 |
| sp|P96709|YDGK_BACSU | Uncharacterized MFS-type transporter YdgK OS=Bacillus subtilis (strain 168) GN=ydgK PE=3 SV=1 | 109 | 256 | 2.0E-08 |
| sp|P31442|EMRD_ECOLI | Multidrug resistance protein D OS=Escherichia coli (strain K12) GN=emrD PE=1 SV=2 | 106 | 269 | 2.0E-08 |
| sp|Q1RI77|BCRH_RICBR | Uncharacterized transporter RBE_0856 OS=Rickettsia bellii (strain RML369-C) GN=RBE_0856 PE=3 SV=1 | 108 | 269 | 6.0E-08 |
| sp|O34307|YVMA_BACSU | Uncharacterized MFS-type transporter YvmA OS=Bacillus subtilis (strain 168) GN=yvmA PE=3 SV=1 | 86 | 260 | 2.0E-07 |
| sp|P32482|CMLA_PSEAI | Chloramphenicol resistance protein OS=Pseudomonas aeruginosa GN=cmlA PE=3 SV=2 | 130 | 269 | 3.0E-07 |
| sp|Q5A6P6|QDR1_CANAL | MFS antiporter QDR1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=QDR PE=2 SV=1 | 106 | 505 | 3.0E-07 |
| sp|P37597|YDHC_ECOLI | Inner membrane transport protein YdhC OS=Escherichia coli (strain K12) GN=ydhC PE=1 SV=3 | 106 | 269 | 5.0E-07 |
| sp|Q7Z118|YMPB_CAEEL | Putative transporter B0361.11 OS=Caenorhabditis elegans GN=B0361.11 PE=3 SV=2 | 131 | 283 | 5.0E-07 |
| sp|Q4UMJ9|BCRH_RICFE | Uncharacterized transporter RF_0358 OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) GN=RF_0358 PE=3 SV=1 | 108 | 248 | 3.0E-06 |
| GO Term | Description | Terminal node |
|---|---|---|
| GO:0016021 | integral component of membrane | Yes |
| GO:0055085 | transmembrane transport | Yes |
| GO:0022857 | transmembrane transporter activity | Yes |
| GO:0031224 | intrinsic component of membrane | No |
| GO:0009987 | cellular process | No |
| GO:0110165 | cellular anatomical entity | No |
| GO:0051179 | localization | No |
| GO:0005215 | transporter activity | No |
| GO:0005575 | cellular_component | No |
| GO:0008150 | biological_process | No |
| GO:0051234 | establishment of localization | No |
| GO:0003674 | molecular_function | No |
| GO:0006810 | transport | No |
| SignalP signal predicted | Location (based on Ymax) |
D score (significance: > 0.45) |
|---|---|---|
| No | 1 - 16 | 0.45 |
| Domain # | Start | End | Length |
|---|---|---|---|
| 1 | 90 | 112 | 22 |
| 2 | 127 | 149 | 22 |
| 3 | 156 | 173 | 17 |
| 4 | 183 | 205 | 22 |
| 5 | 218 | 240 | 22 |
| 6 | 244 | 266 | 22 |
| 7 | 324 | 346 | 22 |
| 8 | 361 | 383 | 22 |
| 9 | 407 | 429 | 22 |
| 10 | 434 | 456 | 22 |
| 11 | 463 | 485 | 22 |
| 12 | 500 | 522 | 22 |
| Type of sequence | Sequence |
|---|---|
| Locus | Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded. |
| Protein | >Hirsu2|10299 MQQQKPQRASEQSDRPAADIPDFESDHSTVPPSSQLPPPERVRTQNGYGVSEEHGRAGAGVGEKDPFEVSWDGGD ADPSCPRSMARGRKWLIVFIVSHASLCFTCASSVYTSTYEQMEAEFHNSRIVSVLGLSSFVLGIGLGPMFLSPLS EFYGRRPIYLVAWTAYLIWFVPQAVAKHIAITIVFRFMSGFSGSAFLAVSGGTVSDLFAKQELQAPMALFSMSPF IGPSLGPLIGGFINYYVDWRWTYYVLVIWSFVLWVAIIFFVPETYHPILLRNKARRLRTETGDDRWIAPGESVKR SVLTAVGRSLLRPFQLLIFEPMCLCLCLFSALLLGILYLLFGAMPLVFGTNHDFNLWNNGLAFLGIAVGVLLGVA TDPLWYRVRIHLIRRHERETGVKDDSEPEFRLPPAILGSVLVPIGLFTFGWSTYPWVPWIVPIIGSAIFGTGNVL LFTGIFTFLVDAYPLYAASALAANAFVRCLFAATFPLFGNQMYKKLGFQWASTLLALLTTAMLPFPYLFFRYGKQ IRARSRFAKE* |
| Coding | >Hirsu2|10299 ATGCAGCAGCAAAAGCCGCAGAGGGCCTCGGAGCAGTCCGACCGCCCGGCGGCCGACATCCCCGACTTCGAGTCC GACCACTCGACCGTGCCGCCGTCCAGCCAGCTGCCGCCGCCCGAGAGGGTCCGGACGCAGAACGGCTACGGCGTG TCGGAGGAGCACGGTCGTGCCGGCGCCGGCGTCGGAGAAAAGGACCCGTTCGAGGTGAGCTGGGACGGCGGCGAC GCCGACCCGTCGTGTCCTCGAAGCATGGCCCGGGGCCGCAAATGGCTCATCGTCTTCATCGTCTCGCACGCCAGC CTGTGCTTCACCTGCGCCAGCTCCGTCTACACGTCGACGTATGAGCAGATGGAAGCCGAGTTCCATAACTCCAGA ATCGTCTCCGTCCTCGGGCTCTCAAGCTTCGTGCTGGGCATCGGCCTCGGGCCCATGTTTCTCAGCCCGCTGAGC GAGTTTTACGGCCGCCGGCCCATCTACCTCGTGGCCTGGACCGCCTATCTCATCTGGTTCGTCCCGCAGGCCGTG GCCAAGCACATCGCCATCACCATCGTCTTCCGCTTCATGAGCGGCTTCTCTGGCAGTGCCTTTCTGGCCGTGTCC GGCGGCACTGTCAGCGACCTTTTCGCCAAGCAAGAGCTGCAGGCCCCCATGGCCCTCTTTTCCATGAGCCCTTTC ATTGGGCCGAGCCTCGGCCCTTTGATCGGGGGCTTCATCAACTACTATGTTGATTGGCGCTGGACTTATTACGTG CTCGTAATCTGGTCCTTTGTCCTTTGGGTAGCCATTATATTCTTTGTTCCCGAGACGTACCACCCCATCTTATTG AGAAACAAGGCACGTAGACTCCGCACGGAGACGGGAGACGACAGATGGATCGCCCCGGGCGAGAGCGTCAAGCGG TCCGTCCTGACGGCGGTTGGACGATCGCTGCTTCGCCCCTTTCAACTGCTCATCTTCGAACCCATGTGCCTCTGC CTCTGCCTGTTCTCCGCCCTGCTCCTGGGTATCCTCTACCTCCTCTTTGGGGCCATGCCCCTCGTCTTCGGCACC AATCATGACTTCAACCTATGGAATAACGGACTGGCCTTCTTGGGCATCGCGGTGGGCGTGCTTCTGGGCGTGGCG ACTGATCCGTTGTGGTACCGCGTCCGCATTCACCTCATTCGCAGGCACGAGCGCGAGACCGGGGTTAAGGACGAC AGCGAGCCCGAGTTTCGACTGCCTCCCGCCATCCTTGGCTCTGTGCTGGTTCCCATCGGTCTGTTCACGTTTGGG TGGTCGACGTACCCGTGGGTGCCCTGGATTGTGCCCATCATTGGGTCGGCCATATTTGGAACCGGCAACGTGTTG CTCTTCACAGGCATCTTCACATTTCTGGTCGACGCCTATCCGCTGTACGCAGCGAGCGCGCTCGCGGCCAACGCA TTCGTCCGCTGTCTGTTTGCCGCGACGTTCCCCCTATTCGGAAATCAGATGTATAAGAAGCTGGGCTTCCAATGG GCCTCGACGCTGCTCGCCTTGCTGACGACCGCCATGCTGCCATTCCCGTACCTCTTCTTTCGCTACGGCAAGCAA ATTCGAGCCAGGAGCCGATTTGCCAAGGAGTAG |
| Transcript | >Hirsu2|10299 ATGCAGCAGCAAAAGCCGCAGAGGGCCTCGGAGCAGTCCGACCGCCCGGCGGCCGACATCCCCGACTTCGAGTCC GACCACTCGACCGTGCCGCCGTCCAGCCAGCTGCCGCCGCCCGAGAGGGTCCGGACGCAGAACGGCTACGGCGTG TCGGAGGAGCACGGTCGTGCCGGCGCCGGCGTCGGAGAAAAGGACCCGTTCGAGGTGAGCTGGGACGGCGGCGAC GCCGACCCGTCGTGTCCTCGAAGCATGGCCCGGGGCCGCAAATGGCTCATCGTCTTCATCGTCTCGCACGCCAGC CTGTGCTTCACCTGCGCCAGCTCCGTCTACACGTCGACGTATGAGCAGATGGAAGCCGAGTTCCATAACTCCAGA ATCGTCTCCGTCCTCGGGCTCTCAAGCTTCGTGCTGGGCATCGGCCTCGGGCCCATGTTTCTCAGCCCGCTGAGC GAGTTTTACGGCCGCCGGCCCATCTACCTCGTGGCCTGGACCGCCTATCTCATCTGGTTCGTCCCGCAGGCCGTG GCCAAGCACATCGCCATCACCATCGTCTTCCGCTTCATGAGCGGCTTCTCTGGCAGTGCCTTTCTGGCCGTGTCC GGCGGCACTGTCAGCGACCTTTTCGCCAAGCAAGAGCTGCAGGCCCCCATGGCCCTCTTTTCCATGAGCCCTTTC ATTGGGCCGAGCCTCGGCCCTTTGATCGGGGGCTTCATCAACTACTATGTTGATTGGCGCTGGACTTATTACGTG CTCGTAATCTGGTCCTTTGTCCTTTGGGTAGCCATTATATTCTTTGTTCCCGAGACGTACCACCCCATCTTATTG AGAAACAAGGCACGTAGACTCCGCACGGAGACGGGAGACGACAGATGGATCGCCCCGGGCGAGAGCGTCAAGCGG TCCGTCCTGACGGCGGTTGGACGATCGCTGCTTCGCCCCTTTCAACTGCTCATCTTCGAACCCATGTGCCTCTGC CTCTGCCTGTTCTCCGCCCTGCTCCTGGGTATCCTCTACCTCCTCTTTGGGGCCATGCCCCTCGTCTTCGGCACC AATCATGACTTCAACCTATGGAATAACGGACTGGCCTTCTTGGGCATCGCGGTGGGCGTGCTTCTGGGCGTGGCG ACTGATCCGTTGTGGTACCGCGTCCGCATTCACCTCATTCGCAGGCACGAGCGCGAGACCGGGGTTAAGGACGAC AGCGAGCCCGAGTTTCGACTGCCTCCCGCCATCCTTGGCTCTGTGCTGGTTCCCATCGGTCTGTTCACGTTTGGG TGGTCGACGTACCCGTGGGTGCCCTGGATTGTGCCCATCATTGGGTCGGCCATATTTGGAACCGGCAACGTGTTG CTCTTCACAGGCATCTTCACATTTCTGGTCGACGCCTATCCGCTGTACGCAGCGAGCGCGCTCGCGGCCAACGCA TTCGTCCGCTGTCTGTTTGCCGCGACGTTCCCCCTATTCGGAAATCAGATGTATAAGAAGCTGGGCTTCCAATGG GCCTCGACGCTGCTCGCCTTGCTGACGACCGCCATGCTGCCATTCCCGTACCTCTTCTTTCGCTACGGCAAGCAA ATTCGAGCCAGGAGCCGATTTGCCAAGGAGTAG |
| Gene | >Hirsu2|10299 ATGCAGCAGCAAAAGCCGCAGAGGGCCTCGGAGCAGTCCGACCGCCCGGCGGCCGACATCCCCGACTTCGAGTCC GACCACTCGACCGTGCCGCCGTCCAGCCAGCTGCCGCCGCCCGAGAGGGTCCGGACGCAGAACGGCTACGGCGTG TCGGAGGAGCACGGTCGTGCCGGCGCCGGCGTCGGAGAAAAGGACCCGTTCGAGGTGAGCTGGGACGGCGGCGAC GCCGACCCGTCGTGTCCTCGAAGCATGGCCCGGGGCCGCAAATGGCTCATCGTCTTCATCGTCTCGCACGCCAGC CTGTGCTTGTAAGTGCTCTCGCCTTGTTTTCCTCCGGTCTTCTTAGCGAGGAAAAGAGAGAGGCAAGGGGGAGAT GGAGAGGGAGGCCGGCAGCGGCAGCGGAAGTGGCTCACCATCTCGGTCCCCCCCCCCCAACCCCTAACCCACTTC TCCTTTCTGCAGCACCTGCGCCAGCTCCGTCTACACGTCGACGTATGAGCAGATGGAAGCCGAGTTCCATAACTC CAGAATCGTCTCCGTCCTCGGGCTCTCAAGCTTCGTGCTGGGCATCGGCCTCGGGCCCATGTTTCTCAGCCCGCT GAGCGAGTTTTACGGCCGCCGGCCCATCTACCTCGTGGCCTGGACCGCCTATCTCATCTGGTTCGTCCCGCAGGC CGTGGCCAAGCACATCGCCATCACCATCGTCTTCCGCTTCATGAGCGGCTTCTCTGGCAGTGCCTTTCTGGCCGT GTCCGGCGGCACTGTCAGCGACCTTTTCGCCAAGCAAGAGCTGCAGGCCCCCATGGCCCTCTTTTCCATGAGCCC TTTCATTGGGCCGAGCCTCGGCCCTTTGATCGGGGGCTTCATCAACTACTATGTTGATTGGCGCTGGACTTATTA CGTGCTCGTAATCTGGTCCTTTGTCCTTTGGGTAGCCATTATATTCTTTGTTCCCGAGACGTACCGTACGCTTTC TCCCCCCCTATGCTTCTCCCTCCCCTTTCCCTCGCCCACTGCTTCCGCATCTCTCCGCTCGGCCGCCAGGGCCGG TATGTCTCACTTCCAGCTCGCTCGAGGGGGAAGGAAAGAGAAAATGACTGACACGAGCGTGCTTTGGGTGGAGCT GCCAGACCCCATCTTATTGAGAAACAAGGCACGTAGACTCCGCACGGAGACGGGAGACGACAGATGGATCGCCCC GGGCGAGAGCGTCAAGCGGTCCGTCCTGACGGCGGTTGGACGATCGCTGCTTCGCCCCTTTCAACTGCTCATCTT CGAACCCATGTGCCTCTGCCTCTGCCTGTTCTCCGCCCTGCTCCTGGGTATCCTCTACCTCCTCTTTGGGGCCAT GCCCCTCGTCTTCGGCACCAATCATGACTTCAACCTATGGAATAACGGACTGGCCTTCTTGGGCATCGCGGTGGG CGTGCTTCTGGGCGTGGCGACTGATCCGTTGTGGTACCGCGTCCGCATTCACCTCATTCGCAGGCACGAGCGCGA GACCGGGGTTAAGGACGACAGCGAGCCCGAGTTTCGACTGCCTCCCGCCATCCTTGGCTCTGTGCTGGTTCCCAT CGGTCTGTTCACGTTTGGGTGGTCGACGTACCCGTGGGTGCCCTGGATTGTGCCCATCATTGGGTCGGCCATATT TGGAACCGGGTAAGTTGTGTCCAGCCACGTGTTGCACAGCATGCCTATCAGGACATGTTGTGCTGTCTAGCATTG TGAAAGAAGGGGGGGAGGGTTGGGAGAGCAGGGAGGAGACGAGGGGGTCAAGGGGGGAGTCCGGCGCTCGCTGCT CTTGTACGAGGCGATTTCCAGTCCAGTTGGGTTGCGAGGATCGTTGATCGTGACCACGGTCCGGCCTTGCTTGGG GCGTTGGTGTAGCTTGGACATGGCCGTCGAGCGAGCCCAGACCTCCCCCACCCCCCTCGGTCGGCGCAGAGCTCC ATGTTTGATTGTCTGGCGTCGAGGGGTTATTCGGTGGCCGTGGCTGACGATTGACACGGCACAGCAACGTGTTGC TCTTCACAGGCATCTTCACATTTCTGGTAAGTCAATCAGATGCGGCCTCCCGGCGGAGTTATCATGGCCGCTTAC CATGTTCACGCCAAAGGTCGACGCCTATCCGCTGTACGCAGCGAGCGCGCTCGCGGCCAACGCATTCGTCCGCTG TCTGTTTGCCGGTAAGATGACTGACCCAGCAAGCATGGGCAATCATGGCATGCTTGGCTTGCTTCTGCGGTCGAA CGTAGGACGCAGATGATACTAACTCAGGGCCACAGCGACGTTCCCCCTATTCGGAAATCAGATGTATAAGAAGCT GGGCTTCCAATGGGCCTCGACGCTGCTCGCCTTGCTGACGACCGCCATGCTGCCATTCCCGTACCTCTTCTTTCG CTACGGCAAGCAAATTCGAGCCAGGAGCCGATTTGCCAAGGAGTAG |