Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	AgabiH97|065390
Gene name
Location	scaffold_3:3104322..3106315
Strand	+
Gene length (bp)	1993
Transcript length (bp)	1632
Coding sequence length (bp)	1632
Protein length (aa)	544

Your browser does not support drawing a protein figure.

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF08031	BBE	Berberine and berberine like	4.3E-09	488	530

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|D4B1Z7|A2478_ARTBC	Uncharacterized FAD-linked oxidoreductase ARB_02478 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_02478 PE=1 SV=1	24	533	4.0E-73
sp|D4AS41|A7056_ARTBC	Uncharacterized FAD-linked oxidoreductase ARB_02478 OS=Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) GN=ARB_07056 PE=1 SV=2	3	541	2.0E-71
sp|O06997|YVDP_BACSU	Uncharacterized FAD-linked oxidoreductase YvdP OS=Bacillus subtilis (strain 168) GN=yvdP PE=1 SV=1	225	530	2.0E-08

GO

GO Term	Description	Terminal node
GO:0016491	oxidoreductase activity	Yes
GO:0050660	flavin adenine dinucleotide binding	Yes
GO:0000166	nucleotide binding	No
GO:0003674	molecular_function	No
GO:0043167	ion binding	No
GO:0005488	binding	No
GO:0097159	organic cyclic compound binding	No
GO:1901363	heterocyclic compound binding	No
GO:0043168	anion binding	No
GO:0003824	catalytic activity	No
GO:0036094	small molecule binding	No
GO:1901265	nucleoside phosphate binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
Yes	1 - 22	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Developmental stages of Agaricus bisporus (strain A15). Published in Pelkmans et al, Applied Microbiology and Biotechnology, 2016

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
Casing	Casing mycelium	23.62	13.31	33.92
Initials	Initials knots	26.24	15.07	37.40
Pileal_Stipeal_center	Stage I stipe center	26.56	15.29	37.82
Pileal_Stipeal_shell	Stage I stipe shell	19.01	10.56	27.47
DIF_stipe_center	Stage II stipe center	32.43	18.98	45.87
DIF_stipe_shell	Stage II stipe shell	33.59	19.70	47.48
DIF_stipe_skin	Stage II stipe skin	29.08	16.92	41.23
DIF_cap_skin	Stage II cap skin	19.89	11.11	28.66
DIF_cap_tissue	Stage II cap tissue	18.95	10.55	27.35
DIF_gill_tissue	Stage II gill tissue	19.04	10.56	27.51
YFB_stipe_center	Young fruiting body stipe center	40.54	24.12	56.96
YFB_stipe_shell	Young fruiting body stipe shell	34.68	20.44	48.91
YFB_stipe_skin	Young fruiting body stipe skin	26.25	15.15	37.36
YFB_cap_skin	Young fruiting body cap skin	20.91	11.79	30.03
YFB_cap_tissue	Young fruiting body cap tissue	34.45	20.35	48.55
YFB_gill_tissue	Young fruiting body gill tissue	21.08	11.88	30.28
YFB_veil	Young fruiting body veil	18.46	10.13	26.80

Differential expression

Label1	Label2	Q-value	Significant difference
Casing	DIF_gill_tissue	0.600400	no
Casing	YFB_stipe_center	0.057350	no
Casing	YFB_stipe_shell	0.222035	no
Casing	YFB_stipe_skin	0.831905	no
Casing	YFB_cap_skin	0.804950	no
Casing	YFB_cap_tissue	0.234962	no
Casing	YFB_gill_tissue	0.817240	no
Casing	YFB_veil	0.528926	no
Casing	Initials	0.837806	no
Casing	Pileal_Stipeal_center	0.812614	no
Casing	Pileal_Stipeal_shell	0.603097	no
Casing	DIF_stipe_center	0.353874	no
Casing	DIF_stipe_shell	0.288092	no
Casing	DIF_stipe_skin	0.603568	no
Casing	DIF_cap_skin	0.701728	no
Casing	DIF_cap_tissue	0.596294	no
DIF_gill_tissue	YFB_stipe_center	0.005671	yes
DIF_gill_tissue	YFB_stipe_shell	0.034837	yes
DIF_gill_tissue	YFB_stipe_skin	0.355963	no
DIF_gill_tissue	YFB_cap_skin	0.862289	no
DIF_gill_tissue	YFB_cap_tissue	0.040947	yes
DIF_gill_tissue	YFB_gill_tissue	0.843944	no
DIF_gill_tissue	YFB_veil	0.960533	no
YFB_stipe_center	YFB_stipe_shell	0.699364	no
YFB_stipe_center	YFB_stipe_skin	0.135150	no
YFB_stipe_center	YFB_cap_skin	0.014956	yes
YFB_stipe_center	YFB_cap_tissue	0.684131	no
YFB_stipe_center	YFB_gill_tissue	0.015819	yes
YFB_stipe_center	YFB_veil	0.003365	yes
YFB_stipe_shell	YFB_stipe_skin	0.416361	no
YFB_stipe_shell	YFB_cap_skin	0.081058	no
YFB_stipe_shell	YFB_cap_tissue	0.990210	no
YFB_stipe_shell	YFB_gill_tissue	0.079305	no
YFB_stipe_shell	YFB_veil	0.023153	yes
YFB_stipe_skin	YFB_cap_skin	0.570663	no
YFB_stipe_skin	YFB_cap_tissue	0.440465	no
YFB_stipe_skin	YFB_gill_tissue	0.582435	no
YFB_stipe_skin	YFB_veil	0.303363	no
YFB_cap_skin	YFB_cap_tissue	0.087927	no
YFB_cap_skin	YFB_gill_tissue	0.988651	no
YFB_cap_skin	YFB_veil	0.801537	no
YFB_cap_tissue	YFB_gill_tissue	0.086750	no
YFB_cap_tissue	YFB_veil	0.022631	yes
YFB_gill_tissue	YFB_veil	0.784153	no
Initials	DIF_gill_tissue	0.362232	no
Initials	YFB_stipe_center	0.145389	no
Initials	YFB_stipe_shell	0.423834	no
Initials	YFB_stipe_skin	0.998855	no
Initials	YFB_cap_skin	0.572494	no
Initials	YFB_cap_tissue	0.437800	no
Initials	YFB_gill_tissue	0.585870	no
Initials	YFB_veil	0.308631	no
Initials	Pileal_Stipeal_center	0.983081	no
Initials	Pileal_Stipeal_shell	0.362170	no
Initials	DIF_stipe_center	0.593554	no
Initials	DIF_stipe_shell	0.507005	no
Initials	DIF_stipe_skin	0.832399	no
Initials	DIF_cap_skin	0.457845	no
Initials	DIF_cap_tissue	0.357201	no
Pileal_Stipeal_center	DIF_gill_tissue	0.335056	no
Pileal_Stipeal_center	YFB_stipe_center	0.159859	no
Pileal_Stipeal_center	YFB_stipe_shell	0.450443	no
Pileal_Stipeal_center	YFB_stipe_skin	0.984931	no
Pileal_Stipeal_center	YFB_cap_skin	0.541927	no
Pileal_Stipeal_center	YFB_cap_tissue	0.463944	no
Pileal_Stipeal_center	YFB_gill_tissue	0.554020	no
Pileal_Stipeal_center	YFB_veil	0.284249	no
Pileal_Stipeal_center	Pileal_Stipeal_shell	0.337866	no
Pileal_Stipeal_center	DIF_stipe_center	0.618958	no
Pileal_Stipeal_center	DIF_stipe_shell	0.533516	no
Pileal_Stipeal_center	DIF_stipe_skin	0.858362	no
Pileal_Stipeal_center	DIF_cap_skin	0.431335	no
Pileal_Stipeal_center	DIF_cap_tissue	0.332527	no
Pileal_Stipeal_shell	DIF_gill_tissue	0.997634	no
Pileal_Stipeal_shell	YFB_stipe_center	0.004928	yes
Pileal_Stipeal_shell	YFB_stipe_shell	0.030372	yes
Pileal_Stipeal_shell	YFB_stipe_skin	0.355101	no
Pileal_Stipeal_shell	YFB_cap_skin	0.858658	no
Pileal_Stipeal_shell	YFB_cap_tissue	0.036228	yes
Pileal_Stipeal_shell	YFB_gill_tissue	0.839658	no
Pileal_Stipeal_shell	YFB_veil	0.962009	no
Pileal_Stipeal_shell	DIF_stipe_center	0.071041	no
Pileal_Stipeal_shell	DIF_stipe_shell	0.050706	no
Pileal_Stipeal_shell	DIF_stipe_skin	0.181328	no
Pileal_Stipeal_shell	DIF_cap_skin	0.941251	no
Pileal_Stipeal_shell	DIF_cap_tissue	0.994603	no
DIF_stipe_center	DIF_gill_tissue	0.066395	no
DIF_stipe_center	YFB_stipe_center	0.539831	no
DIF_stipe_center	YFB_stipe_shell	0.898684	no
DIF_stipe_center	YFB_stipe_skin	0.581973	no
DIF_stipe_center	YFB_cap_skin	0.158357	no
DIF_stipe_center	YFB_cap_tissue	0.909190	no
DIF_stipe_center	YFB_gill_tissue	0.155303	no
DIF_stipe_center	YFB_veil	0.049674	yes
DIF_stipe_center	DIF_stipe_shell	0.951182	no
DIF_stipe_center	DIF_stipe_skin	0.818520	no
DIF_stipe_center	DIF_cap_skin	0.099595	no
DIF_stipe_center	DIF_cap_tissue	0.065465	no
DIF_stipe_shell	DIF_gill_tissue	0.048834	yes
DIF_stipe_shell	YFB_stipe_center	0.629510	no
DIF_stipe_shell	YFB_stipe_shell	0.955471	no
DIF_stipe_shell	YFB_stipe_skin	0.498596	no
DIF_stipe_shell	YFB_cap_skin	0.120676	no
DIF_stipe_shell	YFB_cap_tissue	0.964132	no
DIF_stipe_shell	YFB_gill_tissue	0.120220	no
DIF_stipe_shell	YFB_veil	0.032742	yes
DIF_stipe_shell	DIF_stipe_skin	0.740066	no
DIF_stipe_shell	DIF_cap_skin	0.076086	no
DIF_stipe_shell	DIF_cap_tissue	0.046952	yes
DIF_stipe_skin	DIF_gill_tissue	0.172824	no
DIF_stipe_skin	YFB_stipe_center	0.294241	no
DIF_stipe_skin	YFB_stipe_shell	0.656575	no
DIF_stipe_skin	YFB_stipe_skin	0.831196	no
DIF_stipe_skin	YFB_cap_skin	0.331349	no
DIF_stipe_skin	YFB_cap_tissue	0.673724	no
DIF_stipe_skin	YFB_gill_tissue	0.334259	no
DIF_stipe_skin	YFB_veil	0.138282	no
DIF_stipe_skin	DIF_cap_skin	0.242331	no
DIF_stipe_skin	DIF_cap_tissue	0.169576	no
DIF_cap_skin	DIF_gill_tissue	0.942209	no
DIF_cap_skin	YFB_stipe_center	0.009773	yes
DIF_cap_skin	YFB_stipe_shell	0.053358	no
DIF_cap_skin	YFB_stipe_skin	0.449002	no
DIF_cap_skin	YFB_cap_skin	0.930651	no
DIF_cap_skin	YFB_cap_tissue	0.062995	no
DIF_cap_skin	YFB_gill_tissue	0.918427	no
DIF_cap_skin	YFB_veil	0.894579	no
DIF_cap_skin	DIF_cap_tissue	0.936445	no
DIF_cap_tissue	DIF_gill_tissue	0.992744	no
DIF_cap_tissue	YFB_stipe_center	0.004160	yes
DIF_cap_tissue	YFB_stipe_shell	0.032038	yes
DIF_cap_tissue	YFB_stipe_skin	0.344404	no
DIF_cap_tissue	YFB_cap_skin	0.852172	no
DIF_cap_tissue	YFB_cap_tissue	0.035765	yes
DIF_cap_tissue	YFB_gill_tissue	0.832156	no
DIF_cap_tissue	YFB_veil	0.965089	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>AgabiH97|065390 MRLKALLDFVILVSTWSKGDGNCRCLYNEPCWPTKQDFASLSSYLSQPLLRPVPPASACYPIHNPSGNCSDVQSH RRDSIWRTDQPGAYENINFESHIFQNGSISACYLNTTFGIPCEQGNVPPVGVDARTVEDVQAAVKFAGQHNLRLV VKNTGSGRNAFMIWTHHLKNITYNAGFIPEGGSRKHAVPGLTVGAGVQWYEAYTAAAQNNRFVVGGISTTGRGVD NAVEFTIVKPNGDYAVVNSHHNQDLFWALRGGGPGSWGVLISVTYKTHDLFPLIFSTLKVTFPTPDAATSVVTEL VRLSPILSDLGWGGYGVFSNMSLFLGFPSPNASWGDVKSTILPLFDLAMNASHDPDAVATTTPLANPYELLNPSD GTESQDDPEVGGLAELGSRLLSRNAAELRPEETARLLLSFDFVEVHFVAGGAVGRVEPDSVALNPGWRKAVALVR TAGSWEEGTSAKAINGIQQGLAQDVRALDHISPDSATYMNEASLHEPDFKKSFFGNHYDKLKAIKRKYDPRSLFI VAEGIASDGWDDALTCPR*
Coding	>AgabiH97|065390 ATGAGATTGAAGGCTTTGCTTGATTTTGTCATACTCGTGTCTACCTGGTCGAAAGGGGACGGCAACTGCCGCTGT CTCTATAACGAACCTTGTTGGCCCACCAAACAAGACTTTGCTTCTCTCTCCTCCTATCTGTCCCAGCCCCTCCTC CGTCCCGTACCTCCCGCTTCGGCTTGTTATCCTATTCACAATCCGTCTGGCAACTGTTCCGACGTGCAGAGCCAT CGGCGTGACTCGATCTGGCGTACCGACCAACCTGGTGCATATGAAAATATCAATTTCGAATCTCACATATTCCAG AATGGTTCTATTAGTGCCTGTTACCTCAACACTACTTTCGGAATTCCATGTGAACAGGGAAATGTTCCTCCAGTT GGCGTCGATGCTAGGACGGTGGAAGATGTACAAGCAGCGGTGAAGTTTGCTGGCCAGCACAACCTCCGGCTCGTC GTCAAGAATACAGGTTCTGGACGGAACGCTTTCATGATTTGGACGCATCATCTCAAGAACATAACCTATAACGCC GGATTTATCCCAGAAGGCGGTTCGAGAAAACATGCTGTGCCTGGCTTGACTGTGGGCGCTGGTGTTCAATGGTAT GAAGCCTACACTGCTGCTGCGCAGAACAACCGCTTTGTCGTTGGCGGTATATCTACAACAGGGCGAGGAGTGGAC AACGCCGTCGAGTTTACTATTGTCAAACCGAATGGTGATTATGCCGTAGTCAACTCTCACCATAATCAAGACCTC TTCTGGGCGCTGAGAGGCGGCGGCCCAGGTTCTTGGGGAGTCCTCATCTCTGTGACTTACAAAACGCACGATTTA TTCCCACTTATCTTCTCTACTCTTAAAGTCACCTTCCCTACTCCGGATGCTGCGACTAGCGTCGTCACGGAGCTC GTCAGACTATCTCCCATACTTTCAGACTTGGGCTGGGGAGGTTACGGAGTATTTTCAAATATGAGCCTCTTCCTG GGATTTCCGTCCCCAAATGCCTCGTGGGGAGATGTCAAATCTACCATTCTTCCTCTCTTTGACCTCGCTATGAAT GCTTCCCACGACCCCGATGCTGTCGCTACCACCACACCTCTTGCTAACCCTTATGAGCTCCTGAATCCCAGTGAC GGCACTGAAAGCCAGGATGATCCAGAGGTTGGGGGACTGGCCGAACTCGGGTCCCGGTTATTATCCCGCAACGCT GCCGAGCTGAGACCGGAGGAGACAGCACGGCTTCTTCTGAGCTTTGATTTTGTTGAAGTTCATTTCGTCGCGGGT GGAGCTGTTGGGCGCGTTGAACCCGATTCCGTTGCTCTTAACCCAGGGTGGAGAAAAGCTGTAGCCCTTGTACGT ACGGCAGGAAGTTGGGAAGAAGGAACTTCAGCCAAAGCCATCAACGGGATTCAGCAAGGTCTTGCACAAGATGTT AGAGCCTTGGATCACATATCTCCAGACTCAGCAACATACATGAATGAGGCATCGTTGCATGAGCCGGACTTCAAG AAGTCATTCTTTGGTAACCATTATGACAAATTAAAGGCCATTAAACGAAAGTATGATCCCCGCTCGCTATTTATT GTCGCTGAAGGTATAGCATCTGATGGATGGGATGATGCGTTGACGTGCCCCCGATGA
Transcript	>AgabiH97|065390 ATGAGATTGAAGGCTTTGCTTGATTTTGTCATACTCGTGTCTACCTGGTCGAAAGGGGACGGCAACTGCCGCTGT CTCTATAACGAACCTTGTTGGCCCACCAAACAAGACTTTGCTTCTCTCTCCTCCTATCTGTCCCAGCCCCTCCTC CGTCCCGTACCTCCCGCTTCGGCTTGTTATCCTATTCACAATCCGTCTGGCAACTGTTCCGACGTGCAGAGCCAT CGGCGTGACTCGATCTGGCGTACCGACCAACCTGGTGCATATGAAAATATCAATTTCGAATCTCACATATTCCAG AATGGTTCTATTAGTGCCTGTTACCTCAACACTACTTTCGGAATTCCATGTGAACAGGGAAATGTTCCTCCAGTT GGCGTCGATGCTAGGACGGTGGAAGATGTACAAGCAGCGGTGAAGTTTGCTGGCCAGCACAACCTCCGGCTCGTC GTCAAGAATACAGGTTCTGGACGGAACGCTTTCATGATTTGGACGCATCATCTCAAGAACATAACCTATAACGCC GGATTTATCCCAGAAGGCGGTTCGAGAAAACATGCTGTGCCTGGCTTGACTGTGGGCGCTGGTGTTCAATGGTAT GAAGCCTACACTGCTGCTGCGCAGAACAACCGCTTTGTCGTTGGCGGTATATCTACAACAGGGCGAGGAGTGGAC AACGCCGTCGAGTTTACTATTGTCAAACCGAATGGTGATTATGCCGTAGTCAACTCTCACCATAATCAAGACCTC TTCTGGGCGCTGAGAGGCGGCGGCCCAGGTTCTTGGGGAGTCCTCATCTCTGTGACTTACAAAACGCACGATTTA TTCCCACTTATCTTCTCTACTCTTAAAGTCACCTTCCCTACTCCGGATGCTGCGACTAGCGTCGTCACGGAGCTC GTCAGACTATCTCCCATACTTTCAGACTTGGGCTGGGGAGGTTACGGAGTATTTTCAAATATGAGCCTCTTCCTG GGATTTCCGTCCCCAAATGCCTCGTGGGGAGATGTCAAATCTACCATTCTTCCTCTCTTTGACCTCGCTATGAAT GCTTCCCACGACCCCGATGCTGTCGCTACCACCACACCTCTTGCTAACCCTTATGAGCTCCTGAATCCCAGTGAC GGCACTGAAAGCCAGGATGATCCAGAGGTTGGGGGACTGGCCGAACTCGGGTCCCGGTTATTATCCCGCAACGCT GCCGAGCTGAGACCGGAGGAGACAGCACGGCTTCTTCTGAGCTTTGATTTTGTTGAAGTTCATTTCGTCGCGGGT GGAGCTGTTGGGCGCGTTGAACCCGATTCCGTTGCTCTTAACCCAGGGTGGAGAAAAGCTGTAGCCCTTGTACGT ACGGCAGGAAGTTGGGAAGAAGGAACTTCAGCCAAAGCCATCAACGGGATTCAGCAAGGTCTTGCACAAGATGTT AGAGCCTTGGATCACATATCTCCAGACTCAGCAACATACATGAATGAGGCATCGTTGCATGAGCCGGACTTCAAG AAGTCATTCTTTGGTAACCATTATGACAAATTAAAGGCCATTAAACGAAAGTATGATCCCCGCTCGCTATTTATT GTCGCTGAAGGTATAGCATCTGATGGATGGGATGATGCGTTGACGTGCCCCCGATGA
Gene	>AgabiH97|065390 ATGAGATTGAAGGCTTTGCTTGATTTTGTCATACTCGTGTCTACCTGGTCGAAAGGGGACGGCAACTGCCGCTGT CTCTATAACGAACCTTGTTGGCCCACCAAACAAGACTTTGCTTCTCTCTCCTCCTATCTGTCCCAGCCCCTCCTC CGTCCCGTACCTCCCGCTTCGGCTTGTTATCCTATTCACAATCCGTCTGGCAACTGTTCCGACGTGCAGAGCCAT CGGCGTGACTCGATCTGGCGTACCGACCAACCTGGTGCATATGAAAATATCAATTTCGAATCTCACATATTCCAG AATGGTTCTATTAGTGCCTGTTACCTCAACACTACTTTCGGAATTCCATGTGAACAGGGAAATGTTCCTCCAGTT GGCGTCGATGCTAGGACGGTGGAAGATGTACAAGCAGCGGTGAAGTTTGCTGGCCAGCACAACCTCCGGCTCGTC GTCAAGAATACAGGGTAAGCTCATTTGGAGTATCTTCACTAAAAGTTGTTGACCCATAGACTTTATAAATCCACG GACATGATTATCTCGGCCGTAGTTCTGGACGGAACGCTTTCATGATTTGGACGCATCATCTCAAGAACATAACCT ATAACGCCGGATTTATCCCAGAAGGCGGTTCGAGAAAACATGCTGTGCCTGGTTCGTCTAAGACTAGCTCTCCTT AGCCCTAACGGTTGACCGTTCGACGATAAACAGGCTTGACTGTGGGCGCTGGTGTTCAATGGTATGAAGCCTACA CTGCTGCTGCGCAGAACAACCGCTTTGTCGTTGGCGGTATATCTACAACAGGGTCTAATGGAGCTGCAGGCGGTT GGATCATGGGTGGTGGTCACAGCGTATTTTCTCCAAAATTTGGCCTAGGCGAGGTCAGCACAAATGCCTTACTTA GATGCATCGCTGACTGGGGTTGTGCAGGAGTGGACAACGCCGTCGAGTTTACTATTGTCAAACCGAATGGTGATT ATGCCGTAGTCAACTCTCACCATAATCAAGACCTCTTCTGGGCGCTGAGAGGCGGCGGCCCAGGTTCTTGGGGAG TCCTCATCTCTGTGACTTACAAAACGCACGATTTATTCCCACTTATCTTCTCTACTCTTAAAGTCACCTTCCCTA CTCCGGATGCTGCGACTAGCGTCGTCACGGAGCTCGTCAGACTATCTCCCATACTTTCAGACTTGGGCTGGGGAG GTTACGGAGTATTTTCAAATATGAGCCTCTTCCTGGGATTTCCGTCCCCAAATGCCTCGTGGGGAGATGTCAAAT CTACCATTCTTCCTCTCTTTGACCTCGCTATGAATGCTTCCCACGACCCCGATGCTGTCGCTACCACCACACCTC TTGCTAACCCTTATGAGCTCCTGAATCCCAGTGACGGCACTGAAAGCCAGGATGATCCAGAGGTTGGGGGACTGG CCGAACTCGGGTCCCGGTTATTATCCCGCAACGCTGCCGAGCTGAGACCGGAGGAGACAGCACGGCTTCTTCTGA GCTTTGATTTTGTTGAAGTTCAGTACGTAAAATTCATCCTAGTACAGAAATATCTAACTGACTTGTCATAGTTTC GTCGCGGGTGGAGCTGTTGGGCGCGTTGAACCCGATTCCGTTGCTCTTAACCCAGGGTGGAGAAAAGCTGTAGCC CTTGTACGTACGGCAGGAAGTTGGGAAGAAGGAACTTCAGCCAAAGCCATCAACGGGATTCAGCAAGGTCTTGCA CAAGATGTTAGAGCCTTGGATCACATATCTCCAGACTCAGCAACATACATGAATGAGGTAGAGTGTTTTTCCTGT AGTAGTTAACGACGGTTTATAATTCTCATCACAGGCATCGTTGCATGAGCCGGACTTCAAGAAGTCATTCTTTGG TAACCATTATGACAAATTAAAGGCCATTAAACGAAAGTATGATCCCCGCTCGCTATTTATTGTCGCTGAAGGTAT AGCATCTGATGGATGGGATGATGCGTTGACGTGCCCCCGATGA