Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	AgabiH97|065040
Gene name
Location	scaffold_3:3006399..3008027
Strand	-
Gene length (bp)	1628
Transcript length (bp)	1419
Coding sequence length (bp)	1419
Protein length (aa)	473

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF01328	Peroxidase_2	Peroxidase, family 2	1.1E-47	68	284

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|B9W4V6|APO1_AGRAE	Aromatic peroxygenase OS=Agrocybe aegerita GN=APO1 PE=1 SV=1	12	376	5.0E-131
sp|B9W4V8|APO1_COPRA	Aromatic peroxygenase (Fragments) OS=Coprinellus radians GN=APO PE=1 SV=2	50	282	4.0E-75
sp|Q00668|STCC_EMENI	Putative sterigmatocystin biosynthesis peroxidase stcC OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=stcC PE=3 SV=2	70	277	5.0E-21
sp|P04963|PRXC_LEPFU	Chloroperoxidase OS=Leptoxyphium fumago GN=CPO PE=1 SV=3	69	220	8.0E-07

GO

GO Term	Description	Terminal node
GO:0004601	peroxidase activity	Yes
GO:0003674	molecular_function	No
GO:0016491	oxidoreductase activity	No
GO:0016209	antioxidant activity	No
GO:0003824	catalytic activity	No
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
Yes	1 - 21	0.45

Transmembrane Domains

Domain #	Start	End	Length
1	2	24	22

Transcription Factor Class

(None)

Expression data

Analysis 1: Developmental stages of Agaricus bisporus (strain A15). Published in Pelkmans et al, Applied Microbiology and Biotechnology, 2016

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
Casing	Casing mycelium	98.77	58.08	139.47
Initials	Initials knots	111.37	65.64	157.10
Pileal_Stipeal_center	Stage I stipe center	105.57	53.07	158.06
Pileal_Stipeal_shell	Stage I stipe shell	9.48	4.71	14.24
DIF_stipe_center	Stage II stipe center	8.00	3.85	12.14
DIF_stipe_shell	Stage II stipe shell	10.58	5.34	15.82
DIF_stipe_skin	Stage II stipe skin	86.65	45.36	127.94
DIF_cap_skin	Stage II cap skin	9.36	4.63	14.09
DIF_cap_tissue	Stage II cap tissue	7.63	3.68	11.57
DIF_gill_tissue	Stage II gill tissue	8.10	3.92	12.27
YFB_stipe_center	Young fruiting body stipe center	68.66	31.62	105.69
YFB_stipe_shell	Young fruiting body stipe shell	19.29	9.83	28.75
YFB_stipe_skin	Young fruiting body stipe skin	41.56	21.24	61.89
YFB_cap_skin	Young fruiting body cap skin	8.79	4.30	13.27
YFB_cap_tissue	Young fruiting body cap tissue	7.91	3.82	11.99
YFB_gill_tissue	Young fruiting body gill tissue	12.65	6.45	18.84
YFB_veil	Young fruiting body veil	10.10	4.96	15.24

Differential expression

Label1	Label2	Q-value	Significant difference
Casing	DIF_gill_tissue	0.000613	yes
Casing	YFB_stipe_center	0.325695	no
Casing	YFB_stipe_shell	0.000613	yes
Casing	YFB_stipe_skin	0.001625	yes
Casing	YFB_cap_skin	0.000613	yes
Casing	YFB_cap_tissue	0.000613	yes
Casing	YFB_gill_tissue	0.000613	yes
Casing	YFB_veil	0.000613	yes
Casing	Initials	0.788689	no
Casing	Pileal_Stipeal_center	0.910118	no
Casing	Pileal_Stipeal_shell	0.000613	yes
Casing	DIF_stipe_center	0.000613	yes
Casing	DIF_stipe_shell	0.000613	yes
Casing	DIF_stipe_skin	0.786088	no
Casing	DIF_cap_skin	0.000613	yes
Casing	DIF_cap_tissue	0.000613	yes
DIF_gill_tissue	YFB_stipe_center	0.000613	yes
DIF_gill_tissue	YFB_stipe_shell	0.008457	yes
DIF_gill_tissue	YFB_stipe_skin	0.000613	yes
DIF_gill_tissue	YFB_cap_skin	0.898944	no
DIF_gill_tissue	YFB_cap_tissue	0.972803	no
DIF_gill_tissue	YFB_gill_tissue	0.255586	no
DIF_gill_tissue	YFB_veil	0.658176	no
YFB_stipe_center	YFB_stipe_shell	0.000613	yes
YFB_stipe_center	YFB_stipe_skin	0.172056	no
YFB_stipe_center	YFB_cap_skin	0.000613	yes
YFB_stipe_center	YFB_cap_tissue	0.000613	yes
YFB_stipe_center	YFB_gill_tissue	0.000613	yes
YFB_stipe_center	YFB_veil	0.000613	yes
YFB_stipe_shell	YFB_stipe_skin	0.010412	yes
YFB_stipe_shell	YFB_cap_skin	0.012274	yes
YFB_stipe_shell	YFB_cap_tissue	0.004548	yes
YFB_stipe_shell	YFB_gill_tissue	0.258084	no
YFB_stipe_shell	YFB_veil	0.050085	no
YFB_stipe_skin	YFB_cap_skin	0.000613	yes
YFB_stipe_skin	YFB_cap_tissue	0.000613	yes
YFB_stipe_skin	YFB_gill_tissue	0.000613	yes
YFB_stipe_skin	YFB_veil	0.000613	yes
YFB_cap_skin	YFB_cap_tissue	0.864735	no
YFB_cap_skin	YFB_gill_tissue	0.365159	no
YFB_cap_skin	YFB_veil	0.803877	no
YFB_cap_tissue	YFB_gill_tissue	0.224368	no
YFB_cap_tissue	YFB_veil	0.611141	no
YFB_gill_tissue	YFB_veil	0.646533	no
Initials	DIF_gill_tissue	0.000613	yes
Initials	YFB_stipe_center	0.153005	no
Initials	YFB_stipe_shell	0.000613	yes
Initials	YFB_stipe_skin	0.001140	yes
Initials	YFB_cap_skin	0.000613	yes
Initials	YFB_cap_tissue	0.000613	yes
Initials	YFB_gill_tissue	0.000613	yes
Initials	YFB_veil	0.000613	yes
Initials	Pileal_Stipeal_center	0.928527	no
Initials	Pileal_Stipeal_shell	0.000613	yes
Initials	DIF_stipe_center	0.000613	yes
Initials	DIF_stipe_shell	0.000613	yes
Initials	DIF_stipe_skin	0.516552	no
Initials	DIF_cap_skin	0.000613	yes
Initials	DIF_cap_tissue	0.000613	yes
Pileal_Stipeal_center	DIF_gill_tissue	0.000613	yes
Pileal_Stipeal_center	YFB_stipe_center	0.278579	no
Pileal_Stipeal_center	YFB_stipe_shell	0.000613	yes
Pileal_Stipeal_center	YFB_stipe_skin	0.003365	yes
Pileal_Stipeal_center	YFB_cap_skin	0.000613	yes
Pileal_Stipeal_center	YFB_cap_tissue	0.000613	yes
Pileal_Stipeal_center	YFB_gill_tissue	0.000613	yes
Pileal_Stipeal_center	YFB_veil	0.000613	yes
Pileal_Stipeal_center	Pileal_Stipeal_shell	0.000613	yes
Pileal_Stipeal_center	DIF_stipe_center	0.000613	yes
Pileal_Stipeal_center	DIF_stipe_shell	0.000613	yes
Pileal_Stipeal_center	DIF_stipe_skin	0.684131	no
Pileal_Stipeal_center	DIF_cap_skin	0.000613	yes
Pileal_Stipeal_center	DIF_cap_tissue	0.000613	yes
Pileal_Stipeal_shell	DIF_gill_tissue	0.778030	no
Pileal_Stipeal_shell	YFB_stipe_center	0.000613	yes
Pileal_Stipeal_shell	YFB_stipe_shell	0.027205	yes
Pileal_Stipeal_shell	YFB_stipe_skin	0.000613	yes
Pileal_Stipeal_shell	YFB_cap_skin	0.904184	no
Pileal_Stipeal_shell	YFB_cap_tissue	0.731863	no
Pileal_Stipeal_shell	YFB_gill_tissue	0.512973	no
Pileal_Stipeal_shell	YFB_veil	0.921371	no
Pileal_Stipeal_shell	DIF_stipe_center	0.755051	no
Pileal_Stipeal_shell	DIF_stipe_shell	0.853558	no
Pileal_Stipeal_shell	DIF_stipe_skin	0.000613	yes
Pileal_Stipeal_shell	DIF_cap_skin	0.984924	no
Pileal_Stipeal_shell	DIF_cap_tissue	0.664517	no
DIF_stipe_center	DIF_gill_tissue	0.986511	no
DIF_stipe_center	YFB_stipe_center	0.000613	yes
DIF_stipe_center	YFB_stipe_shell	0.007439	yes
DIF_stipe_center	YFB_stipe_skin	0.000613	yes
DIF_stipe_center	YFB_cap_skin	0.880731	no
DIF_stipe_center	YFB_cap_tissue	0.986745	no
DIF_stipe_center	YFB_gill_tissue	0.235169	no
DIF_stipe_center	YFB_veil	0.637388	no
DIF_stipe_center	DIF_stipe_shell	0.549789	no
DIF_stipe_center	DIF_stipe_skin	0.000613	yes
DIF_stipe_center	DIF_cap_skin	0.777187	no
DIF_stipe_center	DIF_cap_tissue	0.947412	no
DIF_stipe_shell	DIF_gill_tissue	0.571499	no
DIF_stipe_shell	YFB_stipe_center	0.000613	yes
DIF_stipe_shell	YFB_stipe_shell	0.074478	no
DIF_stipe_shell	YFB_stipe_skin	0.000613	yes
DIF_stipe_shell	YFB_cap_skin	0.721057	no
DIF_stipe_shell	YFB_cap_tissue	0.528989	no
DIF_stipe_shell	YFB_gill_tissue	0.737180	no
DIF_stipe_shell	YFB_veil	0.946823	no
DIF_stipe_shell	DIF_stipe_skin	0.000613	yes
DIF_stipe_shell	DIF_cap_skin	0.834315	no
DIF_stipe_shell	DIF_cap_tissue	0.454561	no
DIF_stipe_skin	DIF_gill_tissue	0.000613	yes
DIF_stipe_skin	YFB_stipe_center	0.618321	no
DIF_stipe_skin	YFB_stipe_shell	0.000613	yes
DIF_stipe_skin	YFB_stipe_skin	0.016669	yes
DIF_stipe_skin	YFB_cap_skin	0.000613	yes
DIF_stipe_skin	YFB_cap_tissue	0.000613	yes
DIF_stipe_skin	YFB_gill_tissue	0.000613	yes
DIF_stipe_skin	YFB_veil	0.000613	yes
DIF_stipe_skin	DIF_cap_skin	0.000613	yes
DIF_stipe_skin	DIF_cap_tissue	0.000613	yes
DIF_cap_skin	DIF_gill_tissue	0.802491	no
DIF_cap_skin	YFB_stipe_center	0.000613	yes
DIF_cap_skin	YFB_stipe_shell	0.024187	yes
DIF_cap_skin	YFB_stipe_skin	0.000613	yes
DIF_cap_skin	YFB_cap_skin	0.923188	no
DIF_cap_skin	YFB_cap_tissue	0.758620	no
DIF_cap_skin	YFB_gill_tissue	0.488847	no
DIF_cap_skin	YFB_veil	0.904845	no
DIF_cap_skin	DIF_cap_tissue	0.691736	no
DIF_cap_tissue	DIF_gill_tissue	0.932721	no
DIF_cap_tissue	YFB_stipe_center	0.000613	yes
DIF_cap_tissue	YFB_stipe_shell	0.003365	yes
DIF_cap_tissue	YFB_stipe_skin	0.000613	yes
DIF_cap_tissue	YFB_cap_skin	0.803810	no
DIF_cap_tissue	YFB_cap_tissue	0.959412	no
DIF_cap_tissue	YFB_gill_tissue	0.174757	no
DIF_cap_tissue	YFB_veil	0.537751	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>AgabiH97|065040 MVGFISFVVLAVALVAPAAAFPAHGSLAGLSRQELDDAMSAFGKYKRPPPPPGPLEYGGVKLVNDAEHPFKPPRK GDIRGPCPALNTLANHGYISRNGIESPSNIVRAAMEGFNMNNDLAKFTCYAAFIVNGNMVTDLVSIGEKSKKTGP DPKDQPATIGGLNTHNVFEGDSSMTRADFYDGGDVETFNETLFQGFLEYSYRFGGGRYNLTAAGEYRLKRTQDGI QNNPTFTIVAPRLFSAYSESVNPINLWVDGRQDDGQLRLDHARSFFEAARYPDDFHRAARPMSADNEAVVHAIHP LEPGANVAGVNTYTVDRNAPRLDDKCGIFEYHVNTTLRTLYPNPRGNLLDAIRANIHYFYTSIQARGCTEIFPYG RFEDGKNNAYYAYPDFPEVDLPEYGTFPFPPVDLPPYSDDLVPTSNATASDAPASSAAASSAPASSAAASPEASM AVSEASMAAPEASMAVPEASSA*
Coding	>AgabiH97|065040 ATGGTTGGCTTCATCTCCTTCGTTGTGCTCGCAGTCGCTTTGGTCGCTCCCGCCGCCGCATTCCCAGCACATGGT TCATTAGCTGGATTGTCGAGGCAAGAATTGGATGATGCCATGAGTGCCTTCGGCAAATACAAGAGACCGCCACCA CCCCCAGGACCTCTCGAATATGGTGGTGTCAAGCTCGTCAACGATGCCGAACATCCTTTCAAGCCTCCGCGCAAA GGTGATATCCGTGGTCCTTGCCCGGCTTTGAACACTCTCGCCAACCATGGTTACATCAGCCGCAACGGTATTGAG TCACCTTCAAACATCGTCCGTGCCGCCATGGAAGGTTTCAACATGAACAACGACTTGGCCAAGTTCACCTGCTAC GCTGCCTTCATTGTCAACGGAAACATGGTCACCGACTTGGTCAGTATCGGTGAAAAGTCCAAGAAGACTGGACCC GACCCGAAAGATCAACCGGCGACTATTGGTGGTTTGAACACGCATAACGTGTTTGAGGGTGACAGCTCTATGACT CGAGCTGATTTCTATGATGGTGGCGATGTCGAGACCTTCAACGAGACCCTCTTCCAAGGATTCCTTGAATACAGC TACAGATTCGGTGGTGGAAGGTATAACCTTACCGCTGCTGGCGAGTACCGCCTCAAGCGTACTCAAGACGGTATC CAGAACAACCCCACCTTCACCATCGTCGCTCCCCGACTCTTCTCTGCTTACTCTGAATCCGTCAACCCTATCAAC TTGTGGGTCGATGGACGCCAAGACGATGGACAACTCAGGCTCGACCATGCCCGCAGCTTCTTCGAGGCCGCCCGT TACCCCGATGACTTCCACAGGGCTGCACGCCCCATGAGCGCTGATAACGAGGCCGTCGTGCATGCTATCCATCCC CTTGAGCCAGGAGCCAACGTCGCTGGTGTTAACACTTACACTGTGGACCGTAATGCACCCAGACTTGACGACAAG TGCGGTATCTTCGAGTACCACGTCAACACCACTCTGCGCACGCTCTACCCCAACCCGAGAGGCAACTTGTTGGAC GCGATCAGGGCCAACATCCACTACTTCTATACCTCGATCCAAGCTAGAGGTTGCACCGAAATCTTCCCCTACGGT CGATTCGAGGATGGGAAAAACAATGCTTACTACGCGTACCCTGATTTCCCCGAGGTCGATCTCCCCGAATACGGA ACTTTCCCCTTCCCCCCAGTCGACCTCCCTCCCTACTCTGACGACCTCGTCCCCACATCCAACGCCACTGCATCC GACGCCCCTGCATCCAGTGCTGCCGCATCCAGTGCCCCCGCATCCAGCGCCGCGGCATCACCTGAAGCATCGATG GCGGTTTCTGAAGCATCGATGGCGGCTCCTGAAGCATCGATGGCGGTTCCTGAAGCATCTAGCGCCTAA
Transcript	>AgabiH97|065040 ATGGTTGGCTTCATCTCCTTCGTTGTGCTCGCAGTCGCTTTGGTCGCTCCCGCCGCCGCATTCCCAGCACATGGT TCATTAGCTGGATTGTCGAGGCAAGAATTGGATGATGCCATGAGTGCCTTCGGCAAATACAAGAGACCGCCACCA CCCCCAGGACCTCTCGAATATGGTGGTGTCAAGCTCGTCAACGATGCCGAACATCCTTTCAAGCCTCCGCGCAAA GGTGATATCCGTGGTCCTTGCCCGGCTTTGAACACTCTCGCCAACCATGGTTACATCAGCCGCAACGGTATTGAG TCACCTTCAAACATCGTCCGTGCCGCCATGGAAGGTTTCAACATGAACAACGACTTGGCCAAGTTCACCTGCTAC GCTGCCTTCATTGTCAACGGAAACATGGTCACCGACTTGGTCAGTATCGGTGAAAAGTCCAAGAAGACTGGACCC GACCCGAAAGATCAACCGGCGACTATTGGTGGTTTGAACACGCATAACGTGTTTGAGGGTGACAGCTCTATGACT CGAGCTGATTTCTATGATGGTGGCGATGTCGAGACCTTCAACGAGACCCTCTTCCAAGGATTCCTTGAATACAGC TACAGATTCGGTGGTGGAAGGTATAACCTTACCGCTGCTGGCGAGTACCGCCTCAAGCGTACTCAAGACGGTATC CAGAACAACCCCACCTTCACCATCGTCGCTCCCCGACTCTTCTCTGCTTACTCTGAATCCGTCAACCCTATCAAC TTGTGGGTCGATGGACGCCAAGACGATGGACAACTCAGGCTCGACCATGCCCGCAGCTTCTTCGAGGCCGCCCGT TACCCCGATGACTTCCACAGGGCTGCACGCCCCATGAGCGCTGATAACGAGGCCGTCGTGCATGCTATCCATCCC CTTGAGCCAGGAGCCAACGTCGCTGGTGTTAACACTTACACTGTGGACCGTAATGCACCCAGACTTGACGACAAG TGCGGTATCTTCGAGTACCACGTCAACACCACTCTGCGCACGCTCTACCCCAACCCGAGAGGCAACTTGTTGGAC GCGATCAGGGCCAACATCCACTACTTCTATACCTCGATCCAAGCTAGAGGTTGCACCGAAATCTTCCCCTACGGT CGATTCGAGGATGGGAAAAACAATGCTTACTACGCGTACCCTGATTTCCCCGAGGTCGATCTCCCCGAATACGGA ACTTTCCCCTTCCCCCCAGTCGACCTCCCTCCCTACTCTGACGACCTCGTCCCCACATCCAACGCCACTGCATCC GACGCCCCTGCATCCAGTGCTGCCGCATCCAGTGCCCCCGCATCCAGCGCCGCGGCATCACCTGAAGCATCGATG GCGGTTTCTGAAGCATCGATGGCGGCTCCTGAAGCATCGATGGCGGTTCCTGAAGCATCTAGCGCCTAA
Gene	>AgabiH97|065040 ATGGTTGGCTTCATCTCCTTCGTTGTGCTCGCAGTCGCTTTGGTCGCTCCCGCCGCCGCATTCCCAGCACATGGT TCATTAGCTGGATTGTCGAGGCAAGAATTGGATGATGCCATGAGTGCCTTCGGCAAATACAAGAGACCGCCACCA CCCCCAGGACCTCTCGAATATGGTGGTGTCAAGCTCGTCAACGATGCCGAACATCCTTTCAAGCCTCCGCGCAAA GGTGATATCCGTGGTCCTTGCCCGGCTTTGAACACTCTCGCCAACCATGGTGTACGTGCCATTCTTCGACCTTGC TTCTCGCTTTAATATCTGACCCAATTCACAGTACATCAGCCGCAACGGTATTGAGTCACCTTCAAACATCGTCCG TGCCGCCATGGAAGGTCAGTGCTTCAGCATTTCCTTCACGTTCATTCGCTGACTTTGCGCAGGTTTCAACATGAA CAACGACTTGGCCAAGTTCACCTGCTACGCTGCCTTCATTGTCAACGGAAACATGGTCACCGACTTGGTCAGTAT CGGTGAAAAGTCCAAGAAGACTGGACCCGACCCGAAAGATCAACCGGCGACTATTGGTGGTTTGAACACGCATAA CGTGTTTGAGGGTGACAGCTCTATGACTCGAGGTGAGTTTCGCGCATCGCCACAGTTATCCTAATCAAATGACTT ACTTTGCCTCTAGCTGATTTCTATGATGGTGGCGATGTCGAGACCTTCAACGAGACCCTCTTCCAAGGAGTATGT TGTTTTGTATATTTTGAAGCTTCCAGGATCTGATCACTTCACAGTTCCTTGAATACAGCTACAGATTCGGTGGTG GAAGGTATAACCTTACCGCTGCTGGCGAGTACCGCCTCAAGCGTACTCAAGACGGTATCCAGAACAACCCCACCT TCACCATCGTCGCTCCCCGACTCTTCTCTGCTTACTCTGAATCCGTCAACCCTATCAACTTGTGGGTCGATGGAC GCCAAGACGATGGACAACTCAGGCTCGACCATGCCCGCAGCTTCTTCGAGGCCGCCCGTTACCCCGATGACTTCC ACAGGGCTGCACGCCCCATGAGCGCTGATAACGAGGCCGTCGTGCATGCTATCCATCCCCTTGAGCCAGGAGCCA ACGTCGCTGGTGTTAACACTTACACTGTGGACCGTAATGCACCCAGACTTGACGACAAGTGCGGTATCTTCGAGT ACCACGTCAACACCACTCTGCGCACGCTCTACCCCAACCCGAGAGGCAACTTGTTGGACGCGATCAGGGCCAACA TCCACTACTTCTATACCTCGATCCAAGCTAGAGGTTGCACCGAAATCTTCCCCTACGGTCGATTCGAGGATGGGA AAAACAATGCTTACTACGCGTACCCTGATTTCCCCGAGGTCGATCTCCCCGAATACGGAACTTTCCCCTTCCCCC CAGTCGACCTCCCTCCCTACTCTGACGACCTCGTCCCCACATCCAACGCCACTGCATCCGACGCCCCTGCATCCA GTGCTGCCGCATCCAGTGCCCCCGCATCCAGCGCCGCGGCATCACCTGAAGCATCGATGGCGGTTTCTGAAGCAT CGATGGCGGCTCCTGAAGCATCGATGGCGGTTCCTGAAGCATCTAGCGCCTAA