Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	AgabiH97|057940
Gene name
Location	scaffold_3:1279917..1281731
Strand	-
Gene length (bp)	1814
Transcript length (bp)	1350
Coding sequence length (bp)	1350
Protein length (aa)	450

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF08635	ox_reductase_C	Putative oxidoreductase C terminal domain	2.2E-70	206	347
PF01408	GFO_IDH_MocA	Oxidoreductase family, NAD-binding Rossmann fold	3.2E-23	50	203
PF02894	GFO_IDH_MocA_C	Oxidoreductase family, C-terminal alpha/beta domain	2.0E-05	232	336

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|O14082|YEAH_SCHPO	Uncharacterized protein UNK4.17 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC2E11.17 PE=4 SV=2	47	424	6.0E-121
sp|Q09745|YB64_SCHPO	Uncharacterized protein C12C2.04 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC12C2.04 PE=4 SV=1	42	418	3.0E-112

GO

GO Term	Description	Terminal node
GO:0000166	nucleotide binding	Yes
GO:0003674	molecular_function	No
GO:0005488	binding	No
GO:0097159	organic cyclic compound binding	No
GO:1901363	heterocyclic compound binding	No
GO:0036094	small molecule binding	No
GO:1901265	nucleoside phosphate binding	No

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 14	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Developmental stages of Agaricus bisporus (strain A15). Published in Pelkmans et al, Applied Microbiology and Biotechnology, 2016

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
Casing	Casing mycelium	484.36	230.78	737.95
Initials	Initials knots	251.98	143.47	360.50
Pileal_Stipeal_center	Stage I stipe center	408.33	218.57	598.09
Pileal_Stipeal_shell	Stage I stipe shell	312.68	173.94	451.42
DIF_stipe_center	Stage II stipe center	515.86	263.52	768.20
DIF_stipe_shell	Stage II stipe shell	485.25	245.76	724.74
DIF_stipe_skin	Stage II stipe skin	398.31	213.23	583.38
DIF_cap_skin	Stage II cap skin	262.22	148.01	376.43
DIF_cap_tissue	Stage II cap tissue	300.12	166.31	433.94
DIF_gill_tissue	Stage II gill tissue	345.38	187.41	503.35
YFB_stipe_center	Young fruiting body stipe center	505.94	257.90	753.99
YFB_stipe_shell	Young fruiting body stipe shell	538.54	273.76	803.32
YFB_stipe_skin	Young fruiting body stipe skin	472.20	246.56	697.85
YFB_cap_skin	Young fruiting body cap skin	265.18	150.19	380.16
YFB_cap_tissue	Young fruiting body cap tissue	295.91	165.57	426.26
YFB_gill_tissue	Young fruiting body gill tissue	246.64	139.26	354.01
YFB_veil	Young fruiting body veil	281.17	157.60	404.75

Differential expression

Label1	Label2	Q-value	Significant difference
Casing	DIF_gill_tissue	0.399688	no
Casing	YFB_stipe_center	0.950545	no
Casing	YFB_stipe_shell	0.863814	no
Casing	YFB_stipe_skin	0.969929	no
Casing	YFB_cap_skin	0.068830	no
Casing	YFB_cap_tissue	0.162633	no
Casing	YFB_gill_tissue	0.036228	yes
Casing	YFB_veil	0.116118	no
Casing	Initials	0.046536	yes
Casing	Pileal_Stipeal_center	0.745225	no
Casing	Pileal_Stipeal_shell	0.235601	no
Casing	DIF_stipe_center	0.926419	no
Casing	DIF_stipe_shell	0.997305	no
Casing	DIF_stipe_skin	0.692408	no
Casing	DIF_cap_skin	0.066956	no
Casing	DIF_cap_tissue	0.183689	no
DIF_gill_tissue	YFB_stipe_center	0.286505	no
DIF_gill_tissue	YFB_stipe_shell	0.194728	no
DIF_gill_tissue	YFB_stipe_skin	0.408132	no
DIF_gill_tissue	YFB_cap_skin	0.475154	no
DIF_gill_tissue	YFB_cap_tissue	0.736824	no
DIF_gill_tissue	YFB_gill_tissue	0.318785	no
DIF_gill_tissue	YFB_veil	0.628989	no
YFB_stipe_center	YFB_stipe_shell	0.923630	no
YFB_stipe_center	YFB_stipe_skin	0.910430	no
YFB_stipe_center	YFB_cap_skin	0.036228	yes
YFB_stipe_center	YFB_cap_tissue	0.095478	no
YFB_stipe_center	YFB_gill_tissue	0.017507	yes
YFB_stipe_center	YFB_veil	0.066207	no
YFB_stipe_shell	YFB_stipe_skin	0.806296	no
YFB_stipe_shell	YFB_cap_skin	0.018344	yes
YFB_stipe_shell	YFB_cap_tissue	0.057550	no
YFB_stipe_shell	YFB_gill_tissue	0.008791	yes
YFB_stipe_shell	YFB_veil	0.035309	yes
YFB_stipe_skin	YFB_cap_skin	0.062038	no
YFB_stipe_skin	YFB_cap_tissue	0.157303	no
YFB_stipe_skin	YFB_gill_tissue	0.035537	yes
YFB_stipe_skin	YFB_veil	0.111957	no
YFB_cap_skin	YFB_cap_tissue	0.827049	no
YFB_cap_skin	YFB_gill_tissue	0.889926	no
YFB_cap_skin	YFB_veil	0.917599	no
YFB_cap_tissue	YFB_gill_tissue	0.673351	no
YFB_cap_tissue	YFB_veil	0.929599	no
YFB_gill_tissue	YFB_veil	0.787717	no
Initials	DIF_gill_tissue	0.371565	no
Initials	YFB_stipe_center	0.020790	yes
Initials	YFB_stipe_shell	0.011968	yes
Initials	YFB_stipe_skin	0.033674	yes
Initials	YFB_cap_skin	0.927710	no
Initials	YFB_cap_tissue	0.718454	no
Initials	YFB_gill_tissue	0.969405	no
Initials	YFB_veil	0.826764	no
Initials	Pileal_Stipeal_center	0.122322	no
Initials	Pileal_Stipeal_shell	0.589025	no
Initials	DIF_stipe_center	0.016386	yes
Initials	DIF_stipe_shell	0.037140	yes
Initials	DIF_stipe_skin	0.151656	no
Initials	DIF_cap_skin	0.943766	no
Initials	DIF_cap_tissue	0.685390	no
Pileal_Stipeal_center	DIF_gill_tissue	0.720059	no
Pileal_Stipeal_center	YFB_stipe_center	0.639062	no
Pileal_Stipeal_center	YFB_stipe_shell	0.508032	no
Pileal_Stipeal_center	YFB_stipe_skin	0.772330	no
Pileal_Stipeal_center	YFB_cap_skin	0.184709	no
Pileal_Stipeal_center	YFB_cap_tissue	0.378554	no
Pileal_Stipeal_center	YFB_gill_tissue	0.101059	no
Pileal_Stipeal_center	YFB_veil	0.287994	no
Pileal_Stipeal_center	Pileal_Stipeal_shell	0.496751	no
Pileal_Stipeal_center	DIF_stipe_center	0.600056	no
Pileal_Stipeal_center	DIF_stipe_shell	0.730130	no
Pileal_Stipeal_center	DIF_stipe_skin	0.968262	no
Pileal_Stipeal_center	DIF_cap_skin	0.168934	no
Pileal_Stipeal_center	DIF_cap_tissue	0.403148	no
Pileal_Stipeal_shell	DIF_gill_tissue	0.852098	no
Pileal_Stipeal_shell	YFB_stipe_center	0.150303	no
Pileal_Stipeal_shell	YFB_stipe_shell	0.093505	no
Pileal_Stipeal_shell	YFB_stipe_skin	0.228924	no
Pileal_Stipeal_shell	YFB_cap_skin	0.712234	no
Pileal_Stipeal_shell	YFB_cap_tissue	0.924163	no
Pileal_Stipeal_shell	YFB_gill_tissue	0.542093	no
Pileal_Stipeal_shell	YFB_veil	0.838772	no
Pileal_Stipeal_shell	DIF_stipe_center	0.134423	no
Pileal_Stipeal_shell	DIF_stipe_shell	0.202200	no
Pileal_Stipeal_shell	DIF_stipe_skin	0.550636	no
Pileal_Stipeal_shell	DIF_cap_skin	0.678844	no
Pileal_Stipeal_shell	DIF_cap_tissue	0.942929	no
DIF_stipe_center	DIF_gill_tissue	0.265454	no
DIF_stipe_center	YFB_stipe_center	0.977215	no
DIF_stipe_center	YFB_stipe_shell	0.950627	no
DIF_stipe_center	YFB_stipe_skin	0.879868	no
DIF_stipe_center	YFB_cap_skin	0.027451	yes
DIF_stipe_center	YFB_cap_tissue	0.086070	no
DIF_stipe_center	YFB_gill_tissue	0.012577	yes
DIF_stipe_center	YFB_veil	0.053765	no
DIF_stipe_center	DIF_stipe_shell	0.925104	no
DIF_stipe_center	DIF_stipe_skin	0.544686	no
DIF_stipe_center	DIF_cap_skin	0.027451	yes
DIF_stipe_center	DIF_cap_tissue	0.094657	no
DIF_stipe_shell	DIF_gill_tissue	0.370990	no
DIF_stipe_shell	YFB_stipe_center	0.950891	no
DIF_stipe_shell	YFB_stipe_shell	0.863469	no
DIF_stipe_shell	YFB_stipe_skin	0.966564	no
DIF_stipe_shell	YFB_cap_skin	0.055779	no
DIF_stipe_shell	YFB_cap_tissue	0.139851	no
DIF_stipe_shell	YFB_gill_tissue	0.030372	yes
DIF_stipe_shell	YFB_veil	0.101372	no
DIF_stipe_shell	DIF_stipe_skin	0.674054	no
DIF_stipe_shell	DIF_cap_skin	0.054170	no
DIF_stipe_shell	DIF_cap_tissue	0.157440	no
DIF_stipe_skin	DIF_gill_tissue	0.770699	no
DIF_stipe_skin	YFB_stipe_center	0.584067	no
DIF_stipe_skin	YFB_stipe_shell	0.454694	no
DIF_stipe_skin	YFB_stipe_skin	0.723620	no
DIF_stipe_skin	YFB_cap_skin	0.215960	no
DIF_stipe_skin	YFB_cap_tissue	0.429603	no
DIF_stipe_skin	YFB_gill_tissue	0.124559	no
DIF_stipe_skin	YFB_veil	0.333088	no
DIF_stipe_skin	DIF_cap_skin	0.199377	no
DIF_stipe_skin	DIF_cap_tissue	0.457774	no
DIF_cap_skin	DIF_gill_tissue	0.455495	no
DIF_cap_skin	YFB_stipe_center	0.033906	yes
DIF_cap_skin	YFB_stipe_shell	0.016669	yes
DIF_cap_skin	YFB_stipe_skin	0.054170	no
DIF_cap_skin	YFB_cap_skin	0.984130	no
DIF_cap_skin	YFB_cap_tissue	0.802856	no
DIF_cap_skin	YFB_gill_tissue	0.910838	no
DIF_cap_skin	YFB_veil	0.900393	no
DIF_cap_skin	DIF_cap_tissue	0.771042	no
DIF_cap_tissue	DIF_gill_tissue	0.768556	no
DIF_cap_tissue	YFB_stipe_center	0.118094	no
DIF_cap_tissue	YFB_stipe_shell	0.068830	no
DIF_cap_tissue	YFB_stipe_skin	0.172181	no
DIF_cap_tissue	YFB_cap_skin	0.799219	no
DIF_cap_tissue	YFB_cap_tissue	0.981057	no
DIF_cap_tissue	YFB_gill_tissue	0.639782	no
DIF_cap_tissue	YFB_veil	0.908153	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>AgabiH97|057940 MQSRRTSATAAVRRMSGRRGSGISSRRSSIDPTRLVPMDKVTHIGGGDDFNVVFIGAGNIMFGSDEGPWNHSFRL EHKLGRRLKVVALIDPAIDRATAVLQKKCDSFVVSAYQDTRVYKTLDDFVKNMTPKERPRAIIIGSPPMFRGSLQ PGRDVEMQILKHFPGVAMFVEKPIATGSYEHAQDGYVIAKMITDTKTICSVGYMLRYLKAVQLMKQVIEENNLTV MSTIARYAAAYEAIAKADWWDKSKSGGPIIEQGTHFCDLSRYFGGEVDLESVHAHSLEWDENAGQLSQMRIDESK IAPENRVPRATVATWKYDSGAVGSFTHVASLQGTDYSCEFEVYADGYLLKLVNPYVQPVLYVRTPDDDRERAYSF PDDDPFFSEVSHLIDVIEDIEEDPEAAQILSSYEDAVRTYEFTWAIRSASERSRAAKLKASRDGAKAQKENQTD*
Coding	>AgabiH97|057940 ATGCAGAGCCGCAGAACTTCCGCTACTGCCGCTGTTCGTCGCATGTCCGGGCGACGTGGCTCGGGGATCTCATCG CGTCGCTCCTCGATCGACCCTACGCGGCTAGTTCCCATGGATAAAGTTACCCATATCGGGGGCGGCGACGACTTT AATGTCGTTTTCATAGGCGCAGGCAATATTATGTTTGGTTCTGACGAAGGTCCATGGAATCACTCCTTTCGTTTG GAGCACAAACTCGGCCGCCGCCTCAAAGTCGTAGCACTCATTGACCCTGCTATCGACCGTGCTACCGCGGTTCTC CAGAAAAAGTGCGATTCATTTGTCGTATCGGCCTATCAGGATACGCGCGTCTACAAGACCCTTGATGACTTTGTG AAAAATATGACCCCAAAAGAGAGGCCGCGTGCCATCATCATTGGATCTCCCCCTATGTTCCGGGGGTCTTTGCAA CCAGGTAGAGACGTTGAAATGCAGATCCTGAAACATTTCCCTGGTGTTGCCATGTTCGTCGAGAAACCGATTGCC ACGGGGTCGTACGAACATGCCCAGGATGGATATGTGATCGCAAAGATGATCACGGACACCAAGACCATTTGTTCT GTCGGGTACATGCTGCGTTACCTCAAGGCTGTTCAACTCATGAAACAAGTCATTGAGGAGAACAACTTGACTGTA ATGTCCACTATTGCCCGTTATGCCGCTGCATATGAGGCTATTGCTAAGGCAGATTGGTGGGACAAATCGAAAAGC GGGGGCCCTATAATTGAACAAGGCACCCACTTTTGCGATCTTTCGCGTTATTTCGGTGGTGAAGTCGACCTTGAG AGCGTCCATGCTCATTCACTCGAGTGGGATGAAAATGCTGGCCAGTTGTCGCAAATGCGTATTGATGAGAGCAAG ATAGCCCCGGAAAATAGGGTACCGCGTGCCACTGTAGCAACCTGGAAATACGACAGTGGAGCTGTTGGAAGTTTT ACACACGTTGCCTCTCTTCAAGGGACAGACTACAGTTGTGAATTCGAAGTCTACGCTGACGGATATCTTCTGAAA CTTGTCAACCCTTACGTCCAACCAGTCCTCTACGTTCGAACTCCCGATGATGATCGTGAACGTGCATATTCTTTC CCAGATGACGATCCGTTCTTCTCCGAAGTTTCTCATCTCATTGATGTAATCGAGGATATTGAAGAGGACCCTGAA GCTGCTCAAATCCTTAGCTCGTATGAAGATGCGGTAAGGACGTATGAATTCACTTGGGCTATCCGTTCAGCTAGT GAGCGGTCCCGGGCAGCCAAACTCAAGGCTAGCCGCGACGGAGCTAAGGCGCAAAAAGAAAATCAAACAGACTGA
Transcript	>AgabiH97|057940 ATGCAGAGCCGCAGAACTTCCGCTACTGCCGCTGTTCGTCGCATGTCCGGGCGACGTGGCTCGGGGATCTCATCG CGTCGCTCCTCGATCGACCCTACGCGGCTAGTTCCCATGGATAAAGTTACCCATATCGGGGGCGGCGACGACTTT AATGTCGTTTTCATAGGCGCAGGCAATATTATGTTTGGTTCTGACGAAGGTCCATGGAATCACTCCTTTCGTTTG GAGCACAAACTCGGCCGCCGCCTCAAAGTCGTAGCACTCATTGACCCTGCTATCGACCGTGCTACCGCGGTTCTC CAGAAAAAGTGCGATTCATTTGTCGTATCGGCCTATCAGGATACGCGCGTCTACAAGACCCTTGATGACTTTGTG AAAAATATGACCCCAAAAGAGAGGCCGCGTGCCATCATCATTGGATCTCCCCCTATGTTCCGGGGGTCTTTGCAA CCAGGTAGAGACGTTGAAATGCAGATCCTGAAACATTTCCCTGGTGTTGCCATGTTCGTCGAGAAACCGATTGCC ACGGGGTCGTACGAACATGCCCAGGATGGATATGTGATCGCAAAGATGATCACGGACACCAAGACCATTTGTTCT GTCGGGTACATGCTGCGTTACCTCAAGGCTGTTCAACTCATGAAACAAGTCATTGAGGAGAACAACTTGACTGTA ATGTCCACTATTGCCCGTTATGCCGCTGCATATGAGGCTATTGCTAAGGCAGATTGGTGGGACAAATCGAAAAGC GGGGGCCCTATAATTGAACAAGGCACCCACTTTTGCGATCTTTCGCGTTATTTCGGTGGTGAAGTCGACCTTGAG AGCGTCCATGCTCATTCACTCGAGTGGGATGAAAATGCTGGCCAGTTGTCGCAAATGCGTATTGATGAGAGCAAG ATAGCCCCGGAAAATAGGGTACCGCGTGCCACTGTAGCAACCTGGAAATACGACAGTGGAGCTGTTGGAAGTTTT ACACACGTTGCCTCTCTTCAAGGGACAGACTACAGTTGTGAATTCGAAGTCTACGCTGACGGATATCTTCTGAAA CTTGTCAACCCTTACGTCCAACCAGTCCTCTACGTTCGAACTCCCGATGATGATCGTGAACGTGCATATTCTTTC CCAGATGACGATCCGTTCTTCTCCGAAGTTTCTCATCTCATTGATGTAATCGAGGATATTGAAGAGGACCCTGAA GCTGCTCAAATCCTTAGCTCGTATGAAGATGCGGTAAGGACGTATGAATTCACTTGGGCTATCCGTTCAGCTAGT GAGCGGTCCCGGGCAGCCAAACTCAAGGCTAGCCGCGACGGAGCTAAGGCGCAAAAAGAAAATCAAACAGACTGA
Gene	>AgabiH97|057940 ATGCAGGTATGTGTCCCTCCCAATCCCCCTCCTCGTGCTGTCTCCACGCCCAATTCAGAGCCGCAGAACTTCCGC TACTGCCGCTGTTCGTCGCATGTCCGGGCGACGTGGCTCGGGGATCTCATCGCGTCGCTCCTCGATCGACCCTAC GCGGCTAGTTCCCATGGATAAGTCAGTCCAAGCCATTGTTTCGCAATGCATTGTCTTAACCTCCTACTTGCCATA GAGTTACCCATATCGGGGGCGGCGACGACTTTAATGTCGTTTTCATAGGCGCAGGCAATATTATGTTTGGTCCTG CATATCGCCGCTTTATGTGCTTTCTGTTTGTTCTCATGTCATACAACAGGTTCTGACGAAGGTCCATGGAATCAC TCCTTTCGTTTGGAGCAGTAAGTGAATTCTAGGCTCTGCATATATGCACTTTCTCAAAGTGTACCCAGCAAACTC GGCCGCCGCCTCAAAGTCGTAGCACTCATTGACCCTGCTATCGACCGTGCTACCGCGGTTCTCCAGAAAAAGTGC GATTCATTTGTCGTATCGGCCTATCAGGATACGCGCGTCTACAAGACCCTTGATGACTTTGTGAAAAATATGACC CCAAAAGAGAGGCCGCGTGCCATCATCATTGGATCTCCCCCTATGTTCCGGGGGTCTTTGCAACCAGGTAGAGAC GTTGAAATGCAGATCCTGAAACATTTCCCTGGTGTTGCCATGTTCGTCGAGAAACCGATTGCCACGGGGTCGTAC GAACATGCCCAGGATGGATATGTGATCGCAAAGATGATCACGGACACCAAGACCATTTGTTCTGTCGGGTATGTG ATTTTACTACCTTTTTTTTTTGGGAAAGCTTATACAAAGAATCAGGTACATGCTGCGTTACCTCAAGGCTGTTCA ACTCATGAAACAAGTCATTGAGGAGAACAACTTGACTGTAATGTCCACTATTGCCCGTTATGCCGCTGCATATGA GGCTATTGCTAAGGCAGATTGGTGGGACAAATCGAAAAGGTTTTCGTTCTGTTTTTGGGGTTGATTATCTCTAAA TTTAACTTTACATCAAGCGGGGGCCCTATAATTGAACAAGGCACCCACTTTTGCGATCTTTCGCGTTATTTCGGT GGTGAAGTCGACCTTGAGAGCGTCCATGCTCATTCACTCGAGTGGGATGAAAATGCTGGCCAGTTGTCGCAAATG CGTATTGATGAGAGCAAGATAGCCCCGGAAAATAGGGTACCGCGTGCCACTGTAGCAACCTGGTAAGTTGAATAT GCGGTGATTGGATATTGATTTACCCTCCCATGTAGGAAATACGACAGTGGAGCTGTTGGAAGTTTTACACACGTT GCCTCTCTTCAAGGGACAGACTACAGTTGTGAATTCGAAGTCTACGCTGACGGATATCTTCTGAAGTATGCCCGT CAAAGCTCCCTGCGTGTACTTGCTAACTTCGGATAGACTTGTCAACCCTTACGTCCAACCAGTCCTCTACGTTCG AACTCCCGATGATGATCGTGAACGTGCATATTCTTTCCCAGATGACGATCCGTTCTTCTCCGAAGTTTCTCATCT CATTGATGTAATCGAGGATATTGAAGAGGACCCTGAAGCTGCTCAAATCCTTAGCTCGTATGAAGGTGGGTGCGA GCCACCAAATCACATGGCTAAGCAGGCTAACACATGGTGTAGATGCGGTAAGGACGTATGAATTCACTTGGGCTA TCCGTTCAGCTAGTGAGCGGTCCCGGGCAGCCAAACTCAAGGCTAGCCGCGACGGAGCTAAGGCGCAAAAAGAAA ATCAAACAGACTGA