Fungal Genomics

at Utrecht University

General Properties

Protein IDAgabiH97|040590
Gene name
Locationscaffold_2:559781..561393
Strand+
Gene length (bp)1612
Transcript length (bp)1269
Coding sequence length (bp)1269
Protein length (aa) 423

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PFAM Domains

PFAM Domain ID Short name Long name E-value Start End
PF03446 NAD_binding_2 NAD binding domain of 6-phosphogluconate dehydrogenase 1.0E-31 100 282
PF14833 NAD_binding_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 1.8E-24 287 407

Swissprot hits

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Swissprot ID Swissprot Description Start End E-value
sp|Q9XTI0|3HIDH_CAEEL Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Caenorhabditis elegans GN=B0250.5 PE=3 SV=1 101 413 2.0E-50
sp|P28811|MMSB_PSEAE 3-hydroxyisobutyrate dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=mmsB PE=2 SV=1 98 381 5.0E-48
sp|Q9SUC0|3HIDH_ARATH Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Arabidopsis thaliana GN=At4g20930 PE=2 SV=3 101 378 3.0E-42
sp|Q99L13|3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus musculus GN=Hibadh PE=1 SV=1 77 418 4.0E-42
sp|P31937|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=HIBADH PE=1 SV=2 98 384 4.0E-41
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Swissprot ID Swissprot Description Start End E-value
sp|Q9XTI0|3HIDH_CAEEL Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Caenorhabditis elegans GN=B0250.5 PE=3 SV=1 101 413 2.0E-50
sp|P28811|MMSB_PSEAE 3-hydroxyisobutyrate dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=mmsB PE=2 SV=1 98 381 5.0E-48
sp|Q9SUC0|3HIDH_ARATH Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Arabidopsis thaliana GN=At4g20930 PE=2 SV=3 101 378 3.0E-42
sp|Q99L13|3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Mus musculus GN=Hibadh PE=1 SV=1 77 418 4.0E-42
sp|P31937|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=HIBADH PE=1 SV=2 98 384 4.0E-41
sp|Q5R5E7|3HIDH_PONAB 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Pongo abelii GN=HIBADH PE=2 SV=1 98 384 4.0E-41
sp|Q54CX6|3HIDH_DICDI Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Dictyostelium discoideum GN=hibA PE=3 SV=1 101 413 6.0E-41
sp|P29266|3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Rattus norvegicus GN=Hibadh PE=1 SV=3 77 392 8.0E-41
sp|Q2HJD7|3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Bos taurus GN=HIBADH PE=2 SV=1 98 392 7.0E-40
sp|Q9V8M5|3HIDH_DROME Probable 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Drosophila melanogaster GN=CG15093 PE=2 SV=2 99 413 1.0E-38
sp|Q9I5I6|SERDH_PSEAE NAD-dependent L-serine dehydrogenase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=PA0743 PE=1 SV=1 102 370 7.0E-31
sp|Q0QLF5|HMGD_EUBBA 2-(hydroxymethyl)glutarate dehydrogenase OS=Eubacterium barkeri GN=Hgd PE=1 SV=1 100 382 8.0E-28
sp|P9WNY5|MMSB_MYCTU Probable 3-hydroxyisobutyrate dehydrogenase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=mmsB PE=1 SV=1 157 398 3.0E-22
sp|P9WNY4|MMSB_MYCTO Probable 3-hydroxyisobutyrate dehydrogenase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=mmsB PE=3 SV=1 157 398 3.0E-22
sp|P63936|MMSB_MYCBO Probable 3-hydroxyisobutyrate dehydrogenase OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) GN=mmsB PE=3 SV=1 157 398 3.0E-22
sp|P77161|GLXR_ECOLI 2-hydroxy-3-oxopropionate reductase OS=Escherichia coli (strain K12) GN=glxR PE=2 SV=1 100 382 1.0E-20
sp|F4I907|GLYR2_ARATH Glyoxylate/succinic semialdehyde reductase 2, chloroplastic OS=Arabidopsis thaliana GN=GLYR2 PE=1 SV=1 89 397 2.0E-16
sp|P0ABQ2|GARR_ECOLI 2-hydroxy-3-oxopropionate reductase OS=Escherichia coli (strain K12) GN=garR PE=1 SV=1 100 398 3.0E-16
sp|P0ABQ3|GARR_ECOL6 2-hydroxy-3-oxopropionate reductase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=garR PE=3 SV=1 100 398 3.0E-16
sp|O34948|YKWC_BACSU Uncharacterized oxidoreductase YkwC OS=Bacillus subtilis (strain 168) GN=ykwC PE=3 SV=1 100 376 6.0E-15
sp|Q55702|Y229_SYNY3 Uncharacterized oxidoreductase slr0229 OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=slr0229 PE=3 SV=1 104 376 2.0E-14
sp|P0A9V9|SQUU_SHIFL 3-sulfolactaldehyde reductase OS=Shigella flexneri GN=yihU PE=3 SV=1 100 404 5.0E-14
sp|P0A9V8|SQUU_ECOLI 3-sulfolactaldehyde reductase OS=Escherichia coli (strain K12) GN=yihU PE=1 SV=1 100 404 5.0E-14
sp|O33730|Y1503_SHEFN Uncharacterized oxidoreductase Sfri_1503 OS=Shewanella frigidimarina (strain NCIMB 400) GN=Sfri_1503 PE=3 SV=2 102 385 6.0E-14
sp|Q9L7S0|SQUU_SALTY 3-sulfolactaldehyde reductase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=yihU PE=3 SV=1 100 404 1.0E-13
sp|Q9SZE1|3HID1_ARATH Probable 3-hydroxyisobutyrate dehydrogenase-like 1, mitochondrial OS=Arabidopsis thaliana GN=At4g29120 PE=1 SV=1 87 382 4.0E-13
sp|Q9LSV0|GLYR1_ARATH Glyoxylate/succinic semialdehyde reductase 1 OS=Arabidopsis thaliana GN=GLYR1 PE=1 SV=1 99 395 2.0E-11
sp|P9WNY3|Y770_MYCTU Uncharacterized oxidoreductase Rv0770 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=Rv0770 PE=1 SV=1 100 400 3.0E-09
sp|P9WNY2|Y770_MYCTO Uncharacterized oxidoreductase MT0794 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) GN=MT0794 PE=3 SV=1 100 400 3.0E-09
sp|O34969|YFJR_BACSU Uncharacterized oxidoreductase YfjR OS=Bacillus subtilis (strain 168) GN=yfjR PE=3 SV=2 103 386 2.0E-08
sp|Q46888|YGBJ_ECOLI Uncharacterized oxidoreductase YgbJ OS=Escherichia coli (strain K12) GN=ygbJ PE=3 SV=1 101 422 7.0E-06
sp|Q5ZLS7|GLYR1_CHICK Putative oxidoreductase GLYR1 OS=Gallus gallus GN=GLYR1 PE=2 SV=1 97 395 7.0E-06
sp|A4FUF0|GLYR1_BOVIN Putative oxidoreductase GLYR1 OS=Bos taurus GN=GLYR1 PE=2 SV=1 94 395 8.0E-06
sp|Q5RKH0|GLYR1_RAT Putative oxidoreductase GLYR1 OS=Rattus norvegicus GN=Glyr1 PE=1 SV=1 97 395 9.0E-06
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GO

GO Term Description Terminal node
GO:0051287 NAD binding Yes
GO:0050661 NADP binding Yes
GO:0000166 nucleotide binding No
GO:0003674 molecular_function No
GO:0005488 binding No
GO:0097159 organic cyclic compound binding No
GO:1901363 heterocyclic compound binding No
GO:0036094 small molecule binding No
GO:1901265 nucleoside phosphate binding No

SignalP

[Help with interpreting these statistics]
SignalP signal predicted Location
(based on Ymax)		 D score
(significance: > 0.45)
No 1 - 16 0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Developmental stages of Agaricus bisporus (strain A15). Published in Pelkmans et al, Applied Microbiology and Biotechnology, 2016

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Sequences

Type of sequenceSequence
Locus Download genbank file of locus
The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein >AgabiH97|040590
MVLRLNYCIVRSTCGIQHSDLTSKIWFGFVRPQQSGISIKCSHKAFRAPSHVTVNVPLRVSYVGQSQRESFEISA
LGLRSPGHFLKTMTSEELSSLPTDFGWVGLGAMGFPMAEQLRRKISRTCTLWVYDIDLAATEKFVKQELQYDIGR
DRQGARVKIATSSREVVDKSEFIVTIVPEGSHVKSVYLDENVGLLSASCTAGKHFVDCSTIDITTSLSVGNAVRL
SSEVNPPTFHDAPVSGGTAGASAATLTFMVGIEKDSRHFPLLRHVFSFMGKSIYAMGGPSLGLAAKLSNNYLSGM
IALATSEAMNLGMRLGLDPKTLSDCFSTSSGSSWVNNTVNPVPGVCPDAITSKGYEGGFKIELMKKDMTLAIAAA
REVNASLVLADAGLSAYTAASNDPRCHGRDSRVVYRWLGGVEPDVKN*
Coding >AgabiH97|040590
ATGGTGTTGCGACTCAACTATTGCATCGTCCGTAGCACCTGCGGTATCCAACATTCCGACTTGACGAGCAAGATA
TGGTTTGGCTTCGTAAGGCCCCAACAATCTGGGATCAGTATCAAATGCTCACACAAGGCCTTCCGCGCTCCTTCT
CATGTGACAGTCAATGTGCCCTTGAGGGTATCTTACGTGGGCCAGAGTCAACGTGAGAGTTTTGAGATCAGTGCT
TTGGGTTTGCGCAGCCCAGGCCATTTCCTCAAGACCATGACAAGCGAAGAACTCTCCTCTTTACCGACCGATTTC
GGTTGGGTTGGTCTTGGTGCTATGGGATTTCCAATGGCAGAGCAATTACGCAGGAAAATTTCGCGTACCTGTACA
CTATGGGTGTACGACATTGACCTTGCGGCCACGGAAAAATTTGTGAAACAAGAATTGCAATATGATATTGGGAGA
GATCGCCAGGGTGCTCGGGTTAAAATCGCAACTAGTTCCCGTGAGGTAGTTGACAAGAGCGAATTCATTGTCACC
ATTGTTCCTGAAGGATCTCATGTCAAGTCGGTATACCTGGATGAAAATGTAGGTTTATTGTCTGCCAGCTGTACG
GCTGGGAAGCATTTCGTGGACTGTTCTACAATCGACATTACCACCTCCCTCAGTGTGGGAAACGCTGTTCGGTTA
TCTAGCGAGGTCAATCCACCGACGTTTCATGATGCTCCAGTCTCGGGGGGAACTGCAGGCGCCTCCGCGGCGACG
TTGACGTTTATGGTTGGAATTGAGAAAGATTCGCGGCATTTCCCCCTCCTTCGGCACGTCTTCTCTTTTATGGGA
AAATCAATTTATGCCATGGGAGGGCCGTCACTTGGACTGGCGGCAAAATTGAGCAACAATTACCTTTCAGGGATG
ATAGCACTTGCTACCTCCGAAGCCATGAATCTTGGCATGCGACTTGGACTTGACCCTAAAACACTTTCCGACTGC
TTTTCTACCAGCTCAGGCAGCAGCTGGGTCAACAATACCGTAAATCCTGTGCCCGGAGTATGCCCCGATGCTATC
ACTAGCAAAGGATACGAAGGCGGTTTCAAGATAGAACTGATGAAGAAAGATATGACTTTGGCCATCGCTGCAGCT
CGCGAAGTCAACGCTTCCCTGGTTCTTGCAGATGCTGGACTCTCGGCGTACACAGCGGCGTCTAATGATCCTCGA
TGTCATGGAAGAGACTCACGAGTCGTTTATAGGTGGTTGGGAGGCGTGGAGCCGGATGTGAAGAACTAA
Transcript >AgabiH97|040590
ATGGTGTTGCGACTCAACTATTGCATCGTCCGTAGCACCTGCGGTATCCAACATTCCGACTTGACGAGCAAGATA
TGGTTTGGCTTCGTAAGGCCCCAACAATCTGGGATCAGTATCAAATGCTCACACAAGGCCTTCCGCGCTCCTTCT
CATGTGACAGTCAATGTGCCCTTGAGGGTATCTTACGTGGGCCAGAGTCAACGTGAGAGTTTTGAGATCAGTGCT
TTGGGTTTGCGCAGCCCAGGCCATTTCCTCAAGACCATGACAAGCGAAGAACTCTCCTCTTTACCGACCGATTTC
GGTTGGGTTGGTCTTGGTGCTATGGGATTTCCAATGGCAGAGCAATTACGCAGGAAAATTTCGCGTACCTGTACA
CTATGGGTGTACGACATTGACCTTGCGGCCACGGAAAAATTTGTGAAACAAGAATTGCAATATGATATTGGGAGA
GATCGCCAGGGTGCTCGGGTTAAAATCGCAACTAGTTCCCGTGAGGTAGTTGACAAGAGCGAATTCATTGTCACC
ATTGTTCCTGAAGGATCTCATGTCAAGTCGGTATACCTGGATGAAAATGTAGGTTTATTGTCTGCCAGCTGTACG
GCTGGGAAGCATTTCGTGGACTGTTCTACAATCGACATTACCACCTCCCTCAGTGTGGGAAACGCTGTTCGGTTA
TCTAGCGAGGTCAATCCACCGACGTTTCATGATGCTCCAGTCTCGGGGGGAACTGCAGGCGCCTCCGCGGCGACG
TTGACGTTTATGGTTGGAATTGAGAAAGATTCGCGGCATTTCCCCCTCCTTCGGCACGTCTTCTCTTTTATGGGA
AAATCAATTTATGCCATGGGAGGGCCGTCACTTGGACTGGCGGCAAAATTGAGCAACAATTACCTTTCAGGGATG
ATAGCACTTGCTACCTCCGAAGCCATGAATCTTGGCATGCGACTTGGACTTGACCCTAAAACACTTTCCGACTGC
TTTTCTACCAGCTCAGGCAGCAGCTGGGTCAACAATACCGTAAATCCTGTGCCCGGAGTATGCCCCGATGCTATC
ACTAGCAAAGGATACGAAGGCGGTTTCAAGATAGAACTGATGAAGAAAGATATGACTTTGGCCATCGCTGCAGCT
CGCGAAGTCAACGCTTCCCTGGTTCTTGCAGATGCTGGACTCTCGGCGTACACAGCGGCGTCTAATGATCCTCGA
TGTCATGGAAGAGACTCACGAGTCGTTTATAGGTGGTTGGGAGGCGTGGAGCCGGATGTGAAGAACTAA
Gene >AgabiH97|040590
ATGGTGTTGCGACTCAACTATTGCATCGTCCGTAGCACCTGCGGTATCCAACATTCCGACTTGACGAGGTGCAAT
GATCAGAGATTAACAGTTGCTAGAGTTCCTTGGGTGTATCGCGTCTCTCAGCAAGGTAAAGTTCCTTAAAATGTA
TTCTGCTTGAATCTTCTAAGTACACTCAAATCATTCCCAGATATGGTTTGGCTTCGTAAGGCCCCAACAATCTGG
GATCAGTATCAAATGCTCACACAAGGCCTTCCGCGCTCCTTCTCATGTGACAGTCAATGTGCCCTTGAGGGTATC
TTACGTGGGCCAGAGTCAACGTGAGAGTTTTGAGATCAGTGCTTTGGGTTTGCGCAGCCCAGGCCATTTCCTCAA
GACCATGACAAGCGAAGAACTCTCCTCTTTACCGACCGATTTCGGTTGGGTTGGTCTTGGTGCTATGGGATTTCC
AATGGCAGAGCAATTACGCAGGAAAATTTCGCGTACCTGTACACTATGGGTGTACGACATTGACCTTGCGGCCAC
GGAAAAATTTGTGAAACAAGAATTGCAATATGATATTGGGAGAGATCGCCAGGGTGCTCGGGTTAAAATCGCAAC
TAGTTCCCGTGAGGTAGTTGACAAGAGCGTATGTATCTCAAAATACCCAAACTCACTTTTCTAATACTTAGCGTA
GGAATTCATTGTCACCATTGTTCCTGAAGGCAAGTAATACAAATCTTCGGTTATAAAATTCCAGTTGAAGCTGAA
GATTCTATTTCCGCTTGAAATCAGGATCTCATGTCAAGTCGGTATACCTGGATGAAAATGTAGGTTTATTGTCTG
CCAGCTGTACGGCTGGGAAGCATTTCGTGGACTGGTGCGTAGTCGCGTCTTGCCGTCAAAAGATGGATACTATCG
AGTCCCTCCAGTTCTACAATCGACATTACCACCTCCCTCAGTGTGGGAAACGCTGTTCGGTTATCTAGCGAGGTC
AATCCACCGACGTTTCATGATGCTCCAGTCTCGGGGGGAACTGCAGGCGCCTCCGCGGCGACGTTGACGTTTATG
GTTGGAATTGAGAAAGATTCGCGGCATTTCCCCCTCCTTCGGCACGTCTTCTCTTTTATGGGAAAATCAATTTAT
GCCATGGGAGGGCCGTCACTTGGACTGGCGGCAAAATTGAGCAACAATTACCTTTCAGGGATGATAGCACTTGCT
ACCTCCGAAGCCATGAATCTTGGCATGCGACTTGGACTTGACCCTAAAACACTTTCCGACTGCTTTTCTACCAGC
TCAGGCAGCAGCTGGGTCAACAATACCGTAAATCCTGTGCCCGGAGTATGCCCCGATGCTATCACTAGCAAAGGA
TACGAAGGCGGTTTCAAGATAGAACTGATGAAGAAAGATATGACTTTGGCCATCGCTGCAGCTCGCGAAGTCAAC
GCTTCCCTGGTTCTTGCAGATGCTGGACTCTCGGCGTACACAGCGGCGTCTAATGATCCTCGATGTCATGGAAGA
GACTCACGAGTCGTTTATAGGTGGTGCGTTTGTCATTCTATCAATATTTCTACAGTTGATAATTACTAAAAATGT
TAGGTTGGGAGGCGTGGAGCCGGATGTGAAGAACTAA

© 2022 - Robin Ohm - Utrecht University - The Netherlands

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