Fungal Genomics

Agaricus bisporus var bisporus H39 Agaricus bisporus var bisporus H97 Agaricus bisporus var burnettii H119p4 Aspergillus niger CBS 112.32 Aspergillus niger CBS 113.50 Aspergillus niger CBS 115988 Aspergillus niger CBS 115989 Aspergillus niger CBS 118.52 Aspergillus niger CBS 124.48 Aspergillus niger CBS 131.52 Aspergillus niger CBS 133816 Aspergillus niger CBS 147320 Aspergillus niger CBS 147321 Aspergillus niger CBS 147322 Aspergillus niger CBS 147323 Aspergillus niger CBS 147324 Aspergillus niger CBS 147343 Aspergillus niger CBS 147344 Aspergillus niger CBS 147345 Aspergillus niger CBS 147346 Aspergillus niger CBS 147347 Aspergillus niger CBS 147352 Aspergillus niger CBS 147353 Aspergillus niger CBS 147371 Aspergillus niger CBS 147482 Aspergillus niger CBS 630.78 Aspergillus niger CBS 769.97 Niveomyces coronatus CBS 149186 Ophiocordyceps australis 1348a (Ghana) Ophiocordyceps australis map64 (Brazil) Ophiocordyceps camponoti-floridani Ophiocordyceps camponoti-rufipedis Ophiocordyceps kimflemingae Ophiocordyceps subramaniannii Penicillium roqueforti DTO002I6 Penicillium roqueforti DTO003C3 Penicillium roqueforti DTO003H1 (CBS 147308) Penicillium roqueforti DTO006G1 Penicillium roqueforti DTO006G7 Penicillium roqueforti DTO012A1 Penicillium roqueforti DTO012A2 (CBS 147309) Penicillium roqueforti DTO012A6 (CBS 147310) Penicillium roqueforti DTO012A7 Penicillium roqueforti DTO012A8 Penicillium roqueforti DTO012A9 Penicillium roqueforti DTO013E5 Penicillium roqueforti DTO013F2 Penicillium roqueforti DTO013F5 (CBS 147311) Penicillium roqueforti DTO027I6 Penicillium roqueforti DTO032C6 Penicillium roqueforti DTO039G3 Penicillium roqueforti DTO046C5 Penicillium roqueforti DTO070G2 (CBS 147317) Penicillium roqueforti DTO081F9 (CBS 147318) Penicillium roqueforti DTO101D6 (CBS 147325) Penicillium roqueforti DTO102I9 (CBS 147326) Penicillium roqueforti DTO126G2 (CBS 147330) Penicillium roqueforti DTO127F7 (CBS 147331) Penicillium roqueforti DTO127F9 (CBS 147332) Penicillium roqueforti DTO130C1 (CBS 147333) Penicillium roqueforti DTO163C3 (CBS 147337) Penicillium roqueforti DTO163F5 (CBS 147338) Penicillium roqueforti DTO163G4 (CBS 147339) Penicillium roqueforti DTO265D5 (CBS 147372) Penicillium roqueforti DTO369A1 (CBS 147354) Penicillium roqueforti DTO375B1 (CBS 147355) Penicillium roqueforti DTO377G2 (LCP 96.3914a) Penicillium roqueforti LCP96 04111 Rhodonia placenta FPRL280 Torrubiellomyces zombiae CBS 149187

General Properties

Protein ID	AgabiH97|019810
Gene name
Location	scaffold_10:1279024..1280850
Strand	-
Gene length (bp)	1826
Transcript length (bp)	1557
Coding sequence length (bp)	1557
Protein length (aa)	519

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PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF03807	F420_oxidored	NADP oxidoreductase coenzyme F420-dependent	4.9E-06	22	103

Swissprot hits

Swissprot ID	Swissprot Description	Start	End	E-value
sp|O60078|TYR1_SCHPO	Probable prephenate dehydrogenase [NADP(+)] OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=tyr1 PE=2 SV=1	23	501	2.0E-149
sp|P20049|TYR1_YEAST	Prephenate dehydrogenase [NADP(+)] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TYR1 PE=1 SV=2	22	510	3.0E-141
sp|Q58029|Y612_METJA	Probable arogenate/prephenate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) GN=MJ0612 PE=3 SV=1	22	271	1.0E-13

GO

(None)

SignalP

[Help with interpreting these statistics]

SignalP signal predicted	Location (based on Ymax)	D score (significance: > 0.45)
No	1 - 37	0.45

Transmembrane Domains

(None)

Transcription Factor Class

(None)

Expression data

Analysis 1: Developmental stages of Agaricus bisporus (strain A15). Published in Pelkmans et al, Applied Microbiology and Biotechnology, 2016

Expression values

Label	Description	Expression (RPKM)	Confidence interval (low)	Confidence interval (high)
Casing	Casing mycelium	38.46	21.15	55.78
Initials	Initials knots	32.88	19.11	46.64
Pileal_Stipeal_center	Stage I stipe center	19.12	10.36	27.88
Pileal_Stipeal_shell	Stage I stipe shell	18.83	10.25	27.40
DIF_stipe_center	Stage II stipe center	12.65	6.50	18.79
DIF_stipe_shell	Stage II stipe shell	12.47	6.47	18.46
DIF_stipe_skin	Stage II stipe skin	16.09	8.61	23.57
DIF_cap_skin	Stage II cap skin	21.23	11.79	30.67
DIF_cap_tissue	Stage II cap tissue	16.25	8.73	23.78
DIF_gill_tissue	Stage II gill tissue	17.11	9.23	25.00
YFB_stipe_center	Young fruiting body stipe center	12.86	6.63	19.08
YFB_stipe_shell	Young fruiting body stipe shell	10.20	5.11	15.30
YFB_stipe_skin	Young fruiting body stipe skin	16.98	9.13	24.82
YFB_cap_skin	Young fruiting body cap skin	33.26	19.25	47.26
YFB_cap_tissue	Young fruiting body cap tissue	16.95	9.06	24.84
YFB_gill_tissue	Young fruiting body gill tissue	27.84	14.83	40.85
YFB_veil	Young fruiting body veil	15.65	8.33	22.96

Differential expression

Label1	Label2	Q-value	Significant difference
Casing	DIF_gill_tissue	0.002951	yes
Casing	YFB_stipe_center	0.000613	yes
Casing	YFB_stipe_shell	0.000613	yes
Casing	YFB_stipe_skin	0.002525	yes
Casing	YFB_cap_skin	0.749518	no
Casing	YFB_cap_tissue	0.002951	yes
Casing	YFB_gill_tissue	0.373742	no
Casing	YFB_veil	0.002084	yes
Casing	Initials	0.721106	no
Casing	Pileal_Stipeal_center	0.016386	yes
Casing	Pileal_Stipeal_shell	0.014374	yes
Casing	DIF_stipe_center	0.000613	yes
Casing	DIF_stipe_shell	0.000613	yes
Casing	DIF_stipe_skin	0.002951	yes
Casing	DIF_cap_skin	0.046952	yes
Casing	DIF_cap_tissue	0.001140	yes
DIF_gill_tissue	YFB_stipe_center	0.495895	no
DIF_gill_tissue	YFB_stipe_shell	0.130818	no
DIF_gill_tissue	YFB_stipe_skin	0.988742	no
DIF_gill_tissue	YFB_cap_skin	0.018344	yes
DIF_gill_tissue	YFB_cap_tissue	0.987774	no
DIF_gill_tissue	YFB_gill_tissue	0.136034	no
DIF_gill_tissue	YFB_veil	0.881349	no
YFB_stipe_center	YFB_stipe_shell	0.621333	no
YFB_stipe_center	YFB_stipe_skin	0.500175	no
YFB_stipe_center	YFB_cap_skin	0.001140	yes
YFB_stipe_center	YFB_cap_tissue	0.505497	no
YFB_stipe_center	YFB_gill_tissue	0.010728	yes
YFB_stipe_center	YFB_veil	0.689049	no
YFB_stipe_shell	YFB_stipe_skin	0.135297	no
YFB_stipe_shell	YFB_cap_skin	0.000613	yes
YFB_stipe_shell	YFB_cap_tissue	0.135743	no
YFB_stipe_shell	YFB_gill_tissue	0.001625	yes
YFB_stipe_shell	YFB_veil	0.250684	no
YFB_stipe_skin	YFB_cap_skin	0.018624	yes
YFB_stipe_skin	YFB_cap_tissue	0.998164	no
YFB_stipe_skin	YFB_gill_tissue	0.128955	no
YFB_stipe_skin	YFB_veil	0.890234	no
YFB_cap_skin	YFB_cap_tissue	0.014668	yes
YFB_cap_skin	YFB_gill_tissue	0.680086	no
YFB_cap_skin	YFB_veil	0.012274	yes
YFB_cap_tissue	YFB_gill_tissue	0.125142	no
YFB_cap_tissue	YFB_veil	0.892077	no
YFB_gill_tissue	YFB_veil	0.070499	no
Initials	DIF_gill_tissue	0.020790	yes
Initials	YFB_stipe_center	0.002084	yes
Initials	YFB_stipe_shell	0.000613	yes
Initials	YFB_stipe_skin	0.019715	yes
Initials	YFB_cap_skin	0.983119	no
Initials	YFB_cap_tissue	0.016386	yes
Initials	YFB_gill_tissue	0.706780	no
Initials	YFB_veil	0.013782	yes
Initials	Pileal_Stipeal_center	0.062610	no
Initials	Pileal_Stipeal_shell	0.058926	no
Initials	DIF_stipe_center	0.001625	yes
Initials	DIF_stipe_shell	0.000613	yes
Initials	DIF_stipe_skin	0.013782	yes
Initials	DIF_cap_skin	0.161440	no
Initials	DIF_cap_tissue	0.010412	yes
Pileal_Stipeal_center	DIF_gill_tissue	0.838130	no
Pileal_Stipeal_center	YFB_stipe_center	0.279275	no
Pileal_Stipeal_center	YFB_stipe_shell	0.054170	no
Pileal_Stipeal_center	YFB_stipe_skin	0.820445	no
Pileal_Stipeal_center	YFB_cap_skin	0.061086	no
Pileal_Stipeal_center	YFB_cap_tissue	0.815664	no
Pileal_Stipeal_center	YFB_gill_tissue	0.287292	no
Pileal_Stipeal_center	YFB_veil	0.669256	no
Pileal_Stipeal_center	Pileal_Stipeal_shell	0.980761	no
Pileal_Stipeal_center	DIF_stipe_center	0.248876	no
Pileal_Stipeal_center	DIF_stipe_shell	0.228037	no
Pileal_Stipeal_center	DIF_stipe_skin	0.726627	no
Pileal_Stipeal_center	DIF_cap_skin	0.847105	no
Pileal_Stipeal_center	DIF_cap_tissue	0.736561	no
Pileal_Stipeal_shell	DIF_gill_tissue	0.864784	no
Pileal_Stipeal_shell	YFB_stipe_center	0.308255	no
Pileal_Stipeal_shell	YFB_stipe_shell	0.059318	no
Pileal_Stipeal_shell	YFB_stipe_skin	0.848502	no
Pileal_Stipeal_shell	YFB_cap_skin	0.051932	no
Pileal_Stipeal_shell	YFB_cap_tissue	0.843512	no
Pileal_Stipeal_shell	YFB_gill_tissue	0.263104	no
Pileal_Stipeal_shell	YFB_veil	0.701561	no
Pileal_Stipeal_shell	DIF_stipe_center	0.276817	no
Pileal_Stipeal_shell	DIF_stipe_shell	0.253995	no
Pileal_Stipeal_shell	DIF_stipe_skin	0.755783	no
Pileal_Stipeal_shell	DIF_cap_skin	0.818610	no
Pileal_Stipeal_shell	DIF_cap_tissue	0.765593	no
DIF_stipe_center	DIF_gill_tissue	0.459947	no
DIF_stipe_center	YFB_stipe_center	0.980135	no
DIF_stipe_center	YFB_stipe_shell	0.659145	no
DIF_stipe_center	YFB_stipe_skin	0.469557	no
DIF_stipe_center	YFB_cap_skin	0.000613	yes
DIF_stipe_center	YFB_cap_tissue	0.475436	no
DIF_stipe_center	YFB_gill_tissue	0.009446	yes
DIF_stipe_center	YFB_veil	0.659008	no
DIF_stipe_center	DIF_stipe_shell	0.982231	no
DIF_stipe_center	DIF_stipe_skin	0.594956	no
DIF_stipe_center	DIF_cap_skin	0.119761	no
DIF_stipe_center	DIF_cap_tissue	0.562858	no
DIF_stipe_shell	DIF_gill_tissue	0.423173	no
DIF_stipe_shell	YFB_stipe_center	0.963153	no
DIF_stipe_shell	YFB_stipe_shell	0.686379	no
DIF_stipe_shell	YFB_stipe_skin	0.434403	no
DIF_stipe_shell	YFB_cap_skin	0.000613	yes
DIF_stipe_shell	YFB_cap_tissue	0.437663	no
DIF_stipe_shell	YFB_gill_tissue	0.009446	yes
DIF_stipe_shell	YFB_veil	0.624182	no
DIF_stipe_shell	DIF_stipe_skin	0.559255	no
DIF_stipe_shell	DIF_cap_skin	0.099595	no
DIF_stipe_shell	DIF_cap_tissue	0.527297	no
DIF_stipe_skin	DIF_gill_tissue	0.921341	no
DIF_stipe_skin	YFB_stipe_center	0.625258	no
DIF_stipe_skin	YFB_stipe_shell	0.205053	no
DIF_stipe_skin	YFB_stipe_skin	0.930651	no
DIF_stipe_skin	YFB_cap_skin	0.013485	yes
DIF_stipe_skin	YFB_cap_tissue	0.931506	no
DIF_stipe_skin	YFB_gill_tissue	0.089469	no
DIF_stipe_skin	YFB_veil	0.966355	no
DIF_stipe_skin	DIF_cap_skin	0.487851	no
DIF_stipe_skin	DIF_cap_tissue	0.986433	no
DIF_cap_skin	DIF_gill_tissue	0.616287	no
DIF_cap_skin	YFB_stipe_center	0.130962	no
DIF_cap_skin	YFB_stipe_shell	0.021583	yes
DIF_cap_skin	YFB_stipe_skin	0.593299	no
DIF_cap_skin	YFB_cap_skin	0.150303	no
DIF_cap_skin	YFB_cap_tissue	0.590773	no
DIF_cap_skin	YFB_gill_tissue	0.487445	no
DIF_cap_skin	YFB_veil	0.432917	no
DIF_cap_skin	DIF_cap_tissue	0.499434	no
DIF_cap_tissue	DIF_gill_tissue	0.933586	no
DIF_cap_tissue	YFB_stipe_center	0.594282	no
DIF_cap_tissue	YFB_stipe_shell	0.183309	no
DIF_cap_tissue	YFB_stipe_skin	0.942888	no
DIF_cap_tissue	YFB_cap_skin	0.008457	yes
DIF_cap_tissue	YFB_cap_tissue	0.943786	no
DIF_cap_tissue	YFB_gill_tissue	0.086585	no
DIF_cap_tissue	YFB_veil	0.952375	no

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>AgabiH97|019810 MELPINVDPNVTPNAPEHDQPTIGLIGMGAMGRMYAKLFSQAGWKKIYVCDLPEKYERLKEEYANTPGVFPQPNG YAVSRSADYIVYSVEAEYIDRVVAQYGPSTKVNAIVAGQTSVKAPERAAFERHLPADVHILSCHSLHGPTVSPVG QPLVLIQHRSSKDALTLVENILRSFRSRFVYLSYEEHDSVTANTQAVTHAAFLSMGTAWASAESYPWEQGLYVGG IETAKVNLALRIYSNAWHVYAGLAILNPSARTQIHQYAKSASELFKLMLSGGSGSLEDRTKFKERVEWARKTVFS EWGTHNEIFEEDDNHMPTNSSPLSSRPPSPTRRKPILLSASILDKFSMGMPQTSTQNVVPASPTDPSPLQSSLAP PPNHRPNSHLSLIAMVDCWAHLGINPYTHLQLAATPIFRLFLGVAEHLFQSSTLLKSAIHSAIYDHWHRSDDLEF VVAARGWSQCVSFGSFEVYRKRFEETRGFFESRFEEAGKLGSEMIKAVMESEVRREKEEEERMRKMAV*
Coding	>AgabiH97|019810 ATGGAACTACCCATCAACGTAGATCCCAACGTCACCCCAAATGCCCCTGAACACGATCAGCCAACTATTGGGCTC ATCGGTATGGGCGCCATGGGTCGTATGTACGCTAAATTATTCAGCCAGGCCGGTTGGAAGAAGATTTACGTGTGT GATCTACCAGAAAAGTATGAAAGGCTAAAAGAGGAGTATGCTAATACACCTGGAGTCTTTCCTCAGCCAAATGGA TACGCCGTATCTAGGTCGGCAGACTATATCGTATATTCAGTCGAAGCGGAATATATCGATCGCGTGGTTGCACAG TATGGTCCTTCTACCAAAGTGAATGCGATTGTCGCTGGTCAAACTTCTGTCAAAGCCCCTGAAAGAGCTGCATTC GAAAGACATCTTCCTGCAGATGTACATATTCTTTCTTGTCACTCGCTACATGGACCTACAGTCAGTCCAGTCGGT CAACCTCTTGTTCTTATTCAACATAGATCTAGCAAGGATGCTCTAACACTAGTCGAAAACATCCTCCGTTCATTC CGCTCTCGCTTCGTTTATCTCTCCTACGAAGAGCACGACTCAGTCACTGCCAATACCCAAGCAGTAACACACGCA GCCTTTCTCAGTATGGGCACAGCATGGGCATCAGCCGAATCCTATCCATGGGAACAGGGTCTTTACGTCGGTGGA ATAGAAACAGCAAAAGTCAACCTCGCACTTCGGATTTACTCTAATGCGTGGCATGTTTATGCTGGCCTCGCAATT CTAAACCCAAGTGCTCGCACTCAAATCCATCAATACGCTAAAAGCGCTTCAGAGTTATTTAAACTCATGTTAAGT GGTGGTAGCGGTTCTTTAGAAGATCGCACCAAATTCAAAGAACGCGTTGAATGGGCTCGGAAAACCGTGTTTTCC GAATGGGGAACGCATAACGAGATATTCGAAGAGGACGATAACCATATGCCGACAAATTCTAGTCCACTTTCGTCG AGACCACCGTCTCCTACAAGACGAAAACCAATCTTACTCTCCGCTTCAATTTTAGATAAGTTTAGTATGGGAATG CCACAAACTTCAACACAAAACGTCGTACCAGCATCTCCTACCGATCCTTCACCTCTTCAAAGCTCTCTCGCACCA CCACCCAATCATCGTCCCAATTCTCATCTCTCTCTCATCGCCATGGTTGATTGTTGGGCCCACCTCGGTATAAAC CCTTACACCCACCTTCAACTCGCCGCAACACCCATATTCCGACTATTCCTCGGTGTAGCCGAACATCTATTTCAA TCATCGACTTTATTGAAAAGTGCTATCCATTCGGCGATTTACGATCATTGGCATAGGTCTGATGATTTGGAATTT GTTGTTGCTGCGAGAGGTTGGAGTCAGTGTGTTAGTTTTGGAAGTTTTGAGGTTTATAGGAAGAGGTTTGAGGAG ACGAGAGGGTTTTTTGAGTCGAGGTTTGAGGAGGCTGGGAAATTGGGGAGTGAGATGATTAAAGCGGTGATGGAG AGTGAGGTTAGGAGGGAGAAGGAGGAGGAGGAGAGGATGCGTAAGATGGCGGTATGA
Transcript	>AgabiH97|019810 ATGGAACTACCCATCAACGTAGATCCCAACGTCACCCCAAATGCCCCTGAACACGATCAGCCAACTATTGGGCTC ATCGGTATGGGCGCCATGGGTCGTATGTACGCTAAATTATTCAGCCAGGCCGGTTGGAAGAAGATTTACGTGTGT GATCTACCAGAAAAGTATGAAAGGCTAAAAGAGGAGTATGCTAATACACCTGGAGTCTTTCCTCAGCCAAATGGA TACGCCGTATCTAGGTCGGCAGACTATATCGTATATTCAGTCGAAGCGGAATATATCGATCGCGTGGTTGCACAG TATGGTCCTTCTACCAAAGTGAATGCGATTGTCGCTGGTCAAACTTCTGTCAAAGCCCCTGAAAGAGCTGCATTC GAAAGACATCTTCCTGCAGATGTACATATTCTTTCTTGTCACTCGCTACATGGACCTACAGTCAGTCCAGTCGGT CAACCTCTTGTTCTTATTCAACATAGATCTAGCAAGGATGCTCTAACACTAGTCGAAAACATCCTCCGTTCATTC CGCTCTCGCTTCGTTTATCTCTCCTACGAAGAGCACGACTCAGTCACTGCCAATACCCAAGCAGTAACACACGCA GCCTTTCTCAGTATGGGCACAGCATGGGCATCAGCCGAATCCTATCCATGGGAACAGGGTCTTTACGTCGGTGGA ATAGAAACAGCAAAAGTCAACCTCGCACTTCGGATTTACTCTAATGCGTGGCATGTTTATGCTGGCCTCGCAATT CTAAACCCAAGTGCTCGCACTCAAATCCATCAATACGCTAAAAGCGCTTCAGAGTTATTTAAACTCATGTTAAGT GGTGGTAGCGGTTCTTTAGAAGATCGCACCAAATTCAAAGAACGCGTTGAATGGGCTCGGAAAACCGTGTTTTCC GAATGGGGAACGCATAACGAGATATTCGAAGAGGACGATAACCATATGCCGACAAATTCTAGTCCACTTTCGTCG AGACCACCGTCTCCTACAAGACGAAAACCAATCTTACTCTCCGCTTCAATTTTAGATAAGTTTAGTATGGGAATG CCACAAACTTCAACACAAAACGTCGTACCAGCATCTCCTACCGATCCTTCACCTCTTCAAAGCTCTCTCGCACCA CCACCCAATCATCGTCCCAATTCTCATCTCTCTCTCATCGCCATGGTTGATTGTTGGGCCCACCTCGGTATAAAC CCTTACACCCACCTTCAACTCGCCGCAACACCCATATTCCGACTATTCCTCGGTGTAGCCGAACATCTATTTCAA TCATCGACTTTATTGAAAAGTGCTATCCATTCGGCGATTTACGATCATTGGCATAGGTCTGATGATTTGGAATTT GTTGTTGCTGCGAGAGGTTGGAGTCAGTGTGTTAGTTTTGGAAGTTTTGAGGTTTATAGGAAGAGGTTTGAGGAG ACGAGAGGGTTTTTTGAGTCGAGGTTTGAGGAGGCTGGGAAATTGGGGAGTGAGATGATTAAAGCGGTGATGGAG AGTGAGGTTAGGAGGGAGAAGGAGGAGGAGGAGAGGATGCGTAAGATGGCGGTATGA
Gene	>AgabiH97|019810 ATGGAACTACCCATCAACGTAGATCCCAACGTCACCCCAAATGCCCCTGAACACGATCAGCCAACTATTGGGCTC ATCGGTATGGGCGCCATGGGTCGTATGTACGCTAAATTATTCAGCCAGGCCGGTTGGAAGAAGTGCGTCATTCTC GTTGTATTCCTGTTGTGATCACCGACGCTGTTTTAGGATTTACGTGTGTGATCTACCAGAAAAGTATGAAAGGCT AAAAGAGGAGTATGCTAGTGCGCCTTTTATTGCGATCAGGGTCCGCGAGTTCAGGGTCTAACCACTCGTTCGCAG ATACACCTGGAGTCTTTCCTCAGCCAAATGGATACGCCGTATCTAGGTCGGCAGACTATATCGTATATTCAGTCG AAGCGGAATATATCGATCGCGTGGTTGCACAGTATGGTCCTTGTGAGTCAATTACTCACTCAATCCCTCAAATTA AAACTCTCCAATAGCTACCAAAGTGAATGCGATTGTCGCTGGTCAAACTTCTGTCAAAGCCCCTGAAAGAGCTGC ATTCGAAAGACATCTTCCTGCAGATGTACATATTCTTTCTTGTCACTCGCTACATGGACCTACAGTCAGTCCAGT CGGTCAACCTCTTGTGAGTTTCCTTCCCTTTTTCCTTCTGCGGGAAGTCCCTGATAGATAGACACTAGGTTCTTA TTCAACATAGATCTAGCAAGGATGCTCTAACACTAGTCGAAAACATCCTCCGTTCATTCCGCTCTCGCTTCGTTT ATCTCTCCTACGAAGAGCACGACTCAGTCACTGCCAATACCCAAGCAGTAACACACGCAGCCTTTCTCAGGTGTG AACGCCAAACTTTCTCTCACAAAGTTTAACACCGTACTGACCTGTAGTCAAACAGTATGGGCACAGCATGGGCAT CAGCCGAATCCTATCCATGGGAACAGGGTCTTTACGTCGGTGGAATAGAAACAGCAAAAGTCAACCTCGCACTTC GGATTTACTCTAATGCGTGGCATGTTTATGCTGGCCTCGCAATTCTAAACCCAAGTGCTCGCACTCAAATCCATC AATACGCTAAAAGCGCTTCAGAGTTATTTAAACTCATGTTAAGTGGTGGTAGCGGTTCTTTAGAAGATCGCACCA AATTCAAAGAACGCGTTGAATGGGCTCGGAAAACCGTGTTTTCCGAATGGGGAACGCATAACGAGATATTCGAAG AGGACGATAACCATATGCCGACAAATTCTAGTCCACTTTCGTCGAGACCACCGTCTCCTACAAGACGAAAACCAA TCTTACTCTCCGCTTCAATTTTAGATAAGTTTAGTATGGGAATGCCACAAACTTCAACACAAAACGTCGTACCAG CATCTCCTACCGATCCTTCACCTCTTCAAAGCTCTCTCGCACCACCACCCAATCATCGTCCCAATTCTCATCTCT CTCTCATCGCCATGGTTGATTGTTGGGCCCACCTCGGTATAAACCCTTACACCCACCTTCAACTCGCCGCAACAC CCATATTCCGACTATTCCTCGGTGTAGCCGAACATCTATTTCAATCATCGACTTTATTGAAAAGTGCTATCCATT CGGCGATTTACGATCATTGGCATAGGTCTGATGATTTGGAATTTGTTGTTGCTGCGAGAGGTTGGAGTCAGTGTG TTAGTTTTGGAAGTTTTGAGGTTTATAGGAAGAGGTTTGAGGAGACGAGAGGGTTTTTTGAGTCGAGGTTTGAGG AGGCTGGGAAATTGGGGAGTGAGATGATTAAAGCGGTGATGGAGAGTGAGGTTAGGAGGGAGAAGGAGGAGGAGG AGAGGATGCGTAAGATGGCGGTATGA