Fungal Genomics

at Utrecht University

General Properties

Protein ID	Agabi119p4\|761400
Gene name
Location	scaffold_11:1659376..1663188
Strand	+
Gene length (bp)	3812
Transcript length (bp)	3081
Coding sequence length (bp)	3081
Protein length (aa)	1027

Overview

PFAM Domains

PFAM Domain ID	Short name	Long name	E-value	Start	End
PF16653	Sacchrp_dh_C	Saccharopine dehydrogenase C-terminal domain	1.2E-77	647	1003
PF03435	Sacchrp_dh_NADP	Saccharopine dehydrogenase NADP binding domain	4.4E-16	525	640
PF05222	AlaDh_PNT_N	Alanine dehydrogenase/PNT, N-terminal domain	5.6E-12	22	93

Swissprot hits

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9UDR5\|AASS_HUMAN	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Homo sapiens GN=AASS PE=1 SV=1	4	1003	1.0E-147
sp\|Q99K67\|AASS_MOUSE	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Mus musculus GN=Aass PE=1 SV=1	4	1003	1.0E-145
sp\|A2VCW9\|AASS_RAT	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Rattus norvegicus GN=Aass PE=2 SV=1	4	1003	6.0E-145
sp\|A8E657\|AASS_BOVIN	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Bos taurus GN=AASS PE=2 SV=1	4	1003	1.0E-144
sp\|Q54NG9\|SCPDH_DICDI	Probable saccharopine dehydrogenase [NADP(+), L-glutamate-forming] OS=Dictyostelium discoideum GN=sdh PE=2 SV=1	522	1008	1.0E-68

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Swissprot ID	Swissprot Description	Start	End	E-value
sp\|Q9UDR5\|AASS_HUMAN	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Homo sapiens GN=AASS PE=1 SV=1	4	1003	1.0E-147
sp\|Q99K67\|AASS_MOUSE	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Mus musculus GN=Aass PE=1 SV=1	4	1003	1.0E-145
sp\|A2VCW9\|AASS_RAT	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Rattus norvegicus GN=Aass PE=2 SV=1	4	1003	6.0E-145
sp\|A8E657\|AASS_BOVIN	Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Bos taurus GN=AASS PE=2 SV=1	4	1003	1.0E-144
sp\|Q54NG9\|SCPDH_DICDI	Probable saccharopine dehydrogenase [NADP(+), L-glutamate-forming] OS=Dictyostelium discoideum GN=sdh PE=2 SV=1	522	1008	1.0E-68
sp\|Q9SMZ4\|AASS_ARATH	Alpha-aminoadipic semialdehyde synthase OS=Arabidopsis thaliana GN=LKR/SDH PE=1 SV=1	519	1010	2.0E-64
sp\|P38999\|LYS9_YEAST	Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS9 PE=1 SV=1	522	1000	3.0E-63
sp\|Q9P4R4\|LYS9_MAGO7	Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=LYS3 PE=1 SV=2	522	1000	8.0E-63
sp\|O59711\|LYS9_SCHPO	Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lys9 PE=3 SV=1	524	1009	3.0E-61
sp\|Q9SMZ4\|AASS_ARATH	Alpha-aminoadipic semialdehyde synthase OS=Arabidopsis thaliana GN=LKR/SDH PE=1 SV=1	24	482	4.0E-59
sp\|Q6FU27\|LYS1_CANGA	Saccharopine dehydrogenase [NAD(+), L-lysine-forming] OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN=LYS1 PE=3 SV=1	10	272	1.0E-11
sp\|Q870G1\|LYS1_EMENI	Saccharopine dehydrogenase [NAD(+), L-lysine-forming] OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=lysA PE=3 SV=2	25	175	5.0E-09
sp\|P43065\|LYS1_CANAX	Saccharopine dehydrogenase [NAD(+), L-lysine-forming] OS=Candida albicans GN=LYS1 PE=3 SV=1	11	175	3.0E-08
sp\|P38998\|LYS1_YEAST	Saccharopine dehydrogenase [NAD(+), L-lysine-forming] OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LYS1 PE=1 SV=3	11	175	7.0E-08
sp\|Q09694\|LYS1_SCHPO	Saccharopine dehydrogenase [NAD(+), L-lysine-forming] OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=lys3 PE=1 SV=2	25	245	2.0E-07
sp\|P38997\|LYS1_YARLI	Saccharopine dehydrogenase [NAD(+), L-lysine-forming] OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=LYS5 PE=3 SV=1	11	175	1.0E-06

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GO

GO Term	Description	Terminal node
GO:0016491	oxidoreductase activity	Yes
GO:0003674	molecular_function	No
GO:0003824	catalytic activity	No

Deeploc

Deeploc data not available for this genome

SignalP

(None)

Transmembrane Domains

(None)

Transcription Factor Class

(None)

CAZymes

(None)

Secondary Metabolism

(None)

Expression data

No expression data available for this genome

Orthologs

Orthofinder run ID	5
Orthogroup	9117
Change Orthofinder run

Species	Protein ID
Agaricus bisporus var bisporus H39	AgabiH39\|027570
Agaricus bisporus var bisporus H97	AgabiH97\|027570
Agaricus bisporus var burnettii H119p4	Agabi119p4\|761400 (this protein)

Sequences

Type of sequence	Sequence
Locus	Download genbank file of locus Download genbank file of locus (reverse complement) The gene with 5 kb flanks (if sufficient flanking sequence is available). For use in cloning design programs. NOTE: features (genes or exons) that are only partially contained within the sequence are completely excluded.
Protein	>Agabi119p4\|761400 MKPSRSLLQNVVLAMRREDPARIWERRAPLTPDAVHHLVEKDGVEVLVEPCERRVFTAHEYEKAGAKITSSFDRA HVVIGIKENPMDALAGQRAPVANGNIPRTQVMFSHTAKGQTYNTGLLSQFVAPTDGVLAPSAAEFEKTLELWPRL IDYELLTDDKGKRTVGFGWYAGVAGVLESLSAMAHAHLELGIASPFLYTPRPHTLPCLERLRVALREVGQWISTQ GTPRALGPLVICVTGTGNVAQGCLSILEDLPLKKIDVRELESLVRSDGTSDLFTLAQLLTMNDQIYLVHAKPQDY LVRKDGKSYDRQDYYANPSEWQSLFGERIMPYVTLFLNGTGWASGFPSILTTQQLSNAIAKAQSLGIPSAVTRAR CIGDISCDIGGGLEFLERSTTISEPTYKFAVSDTSGDITMMSVDILPTALPLDASRHFSKEFFPYLRTLINQVGK SNNKGGGEELTRALERATIASNGKLKEKHEWLQPAVDQWHQEQRGVKGIQHMNDSVQVGGTGADRIRGVKKKKMV MFGSGMVAGPAVEEIAKRGDVELVIATNLLGEAQKLAIRYGQEHNNIKYRIVDVAKKETYEHLVNEADVVISLLP AAYHVDIAEMCISGKKHLVTASYISEPMRHLHDRALSADVLLLNEIGLDPGIDHCSAISLINDLKAKGKQVVSFT SFCGGLPAPDSIFDTSSSSSMMMKKRAVPLKYKFSWSPVGVLRAANQGVRYLLNDKVVKLPGMELLRSGFPRLPI LSGKEGDGDGVELEGMPNRDSLPYRETYGLRGEEGESLRTLVRGTLRYPGFCSLMQSFKDIGLLEDGRKIQIGEW NEFLRQVLAVRLGSSSSLGLDGSLESALRDVQGVGEKQYEETMGALEWLGLLSNSNGGGGKKMMVPMKEATPLEL FAMVLGNKLKYGPMERDMVVLSHEVIVRNNQNQQQPQQEEVHRSTLVAYGDESASAMAKTVGLPVAFAALDVLDG KVGMRGVCGPNEREIYESVLGRLEEVGLGMVESVDLVGREGLRTVEESLRG*
Coding	>Agabi119p4\|761400 ATGAAGCCCTCCCGATCACTGTTGCAGAATGTTGTCCTCGCCATGCGCAGAGAGGATCCAGCGAGGATCTGGGAA CGTCGCGCTCCTCTCACCCCCGACGCCGTCCACCATCTCGTCGAGAAGGACGGCGTCGAGGTCCTTGTCGAGCCC TGCGAACGACGTGTCTTTACAGCTCATGAATACGAAAAGGCTGGCGCAAAGATCACTTCCTCCTTTGACCGAGCA CACGTTGTGATAGGCATCAAAGAGAATCCAATGGACGCACTCGCAGGCCAGCGGGCTCCTGTTGCCAATGGAAAC ATACCCCGCACACAAGTCATGTTCTCACATACCGCCAAAGGCCAAACCTACAACACCGGTCTGCTATCTCAGTTT GTCGCCCCGACAGACGGCGTCCTCGCACCATCTGCAGCCGAATTTGAAAAGACGCTTGAGCTGTGGCCGCGGTTG ATTGATTATGAGCTTTTGACCGACGACAAAGGCAAGCGCACTGTAGGATTTGGATGGTATGCAGGTGTCGCCGGT GTCCTTGAATCCTTGTCCGCCATGGCTCACGCCCACCTCGAACTCGGCATCGCCTCTCCCTTTCTCTACACGCCC CGACCTCATACGCTTCCGTGTCTTGAACGCCTTCGTGTTGCATTGCGCGAGGTTGGACAATGGATTTCTACGCAG GGTACTCCAAGGGCCCTTGGTCCTTTGGTTATCTGCGTCACTGGAACGGGTAACGTTGCTCAGGGGTGCCTCTCC ATCCTCGAGGACCTGCCACTGAAGAAGATTGATGTACGTGAATTAGAGAGTCTCGTACGCTCAGACGGCACGTCG GACTTGTTCACACTCGCTCAACTACTGACAATGAATGACCAGATATACTTGGTGCACGCGAAACCACAAGATTAT TTAGTTCGGAAAGACGGCAAGTCATATGATCGCCAGGATTATTATGCAAACCCTAGCGAGTGGCAAAGTCTATTT GGCGAACGCATTATGCCCTATGTGACTCTTTTCCTCAATGGCACCGGGTGGGCATCCGGTTTCCCTTCCATCTTG ACTACCCAGCAACTTTCAAATGCTATTGCGAAAGCGCAGTCTCTTGGTATTCCTAGTGCTGTCACCAGAGCTAGA TGCATCGGTGATATCAGCTGCGATATTGGGGGAGGCCTTGAATTCCTGGAACGTTCAACTACGATCTCTGAACCG ACTTACAAATTTGCTGTTTCTGATACGAGTGGCGATATCACCATGATGTCAGTTGATATTCTCCCCACTGCACTT CCGTTAGACGCATCGCGACATTTTTCGAAAGAATTTTTCCCTTATCTTCGTACACTCATAAATCAAGTTGGGAAG AGTAATAATAAGGGTGGTGGTGAAGAGTTGACGAGAGCACTTGAGAGAGCGACGATTGCGTCTAATGGAAAATTG AAGGAGAAGCATGAATGGTTGCAGCCTGCGGTGGATCAATGGCATCAAGAACAAAGAGGTGTGAAAGGAATACAA CATATGAATGATTCTGTTCAAGTTGGTGGGACTGGTGCGGATAGGATTAGAGGTGTGAAGAAGAAGAAGATGGTG ATGTTTGGAAGTGGGATGGTTGCTGGACCTGCGGTTGAGGAGATTGCGAAAAGGGGGGATGTTGAACTTGTTATT GCGACGAATTTACTGGGAGAGGCTCAGAAGCTTGCGATACGATATGGACAGGAACATAATAATATCAAGTATCGG ATTGTGGATGTTGCGAAGAAGGAGACTTATGAGCATTTGGTTAATGAGGCGGATGTTGTCATCAGTTTGTTACCT GCGGCATATCATGTTGATATTGCGGAGATGTGTATTTCGGGAAAGAAACATCTCGTTACTGCATCTTACATCTCC GAACCCATGCGTCATCTCCATGATCGAGCCTTATCAGCTGATGTGTTGCTGCTTAATGAAATTGGACTTGATCCG GGGATAGATCATTGTTCAGCGATTTCGTTGATCAATGATTTGAAAGCAAAGGGAAAACAAGTTGTTTCGTTTACG TCGTTTTGTGGAGGATTGCCTGCACCGGATTCGATATTCGATACGTCGTCGTCGTCGTCGATGATGATGAAGAAG AGGGCGGTACCGTTGAAGTATAAATTTAGTTGGAGTCCTGTGGGTGTTTTGAGAGCTGCGAATCAGGGGGTGAGG TATTTGCTAAATGACAAGGTTGTGAAACTTCCGGGGATGGAGTTACTTCGGTCTGGGTTTCCGAGGTTACCGATT TTGAGTGGGAAGGAGGGTGATGGTGATGGCGTAGAGTTGGAGGGGATGCCGAATAGAGATAGTTTGCCGTATAGG GAGACTTATGGATTACGAGGTGAGGAGGGTGAGAGTTTGAGGACGTTGGTGCGAGGTACACTTCGGTATCCGGGG TTTTGTTCTTTGATGCAGTCGTTTAAGGATATTGGGTTGCTTGAAGATGGGAGGAAAATTCAAATTGGGGAGTGG AATGAGTTTTTGAGGCAAGTGCTTGCTGTGAGACTTGGATCGTCATCGTCGTTGGGTTTGGATGGGAGTTTGGAA AGTGCTCTTAGGGATGTGCAAGGGGTCGGAGAGAAGCAGTATGAGGAGACGATGGGTGCGTTGGAGTGGTTGGGT TTGTTGTCGAATTCGAATGGAGGAGGAGGGAAGAAGATGATGGTTCCGATGAAGGAAGCTACGCCTTTAGAGTTG TTTGCTATGGTTTTGGGAAACAAGTTGAAGTATGGGCCGATGGAAAGGGATATGGTCGTACTCTCTCATGAAGTT ATCGTTCGCAACAACCAAAACCAACAACAACCTCAACAAGAAGAAGTTCATCGATCGACTCTAGTCGCATATGGA GATGAATCCGCATCTGCTATGGCGAAAACGGTTGGTCTTCCTGTGGCGTTTGCAGCGCTAGATGTGTTGGATGGG AAAGTGGGGATGAGAGGGGTGTGTGGACCGAATGAGAGGGAGATTTATGAGAGTGTTTTGGGGAGGTTGGAGGAG GTTGGGTTGGGGATGGTTGAGAGTGTGGATTTGGTTGGGAGGGAGGGGTTGAGGACTGTAGAGGAGAGTTTGAGG GGGTAA
Transcript	>Agabi119p4\|761400 ATGAAGCCCTCCCGATCACTGTTGCAGAATGTTGTCCTCGCCATGCGCAGAGAGGATCCAGCGAGGATCTGGGAA CGTCGCGCTCCTCTCACCCCCGACGCCGTCCACCATCTCGTCGAGAAGGACGGCGTCGAGGTCCTTGTCGAGCCC TGCGAACGACGTGTCTTTACAGCTCATGAATACGAAAAGGCTGGCGCAAAGATCACTTCCTCCTTTGACCGAGCA CACGTTGTGATAGGCATCAAAGAGAATCCAATGGACGCACTCGCAGGCCAGCGGGCTCCTGTTGCCAATGGAAAC ATACCCCGCACACAAGTCATGTTCTCACATACCGCCAAAGGCCAAACCTACAACACCGGTCTGCTATCTCAGTTT GTCGCCCCGACAGACGGCGTCCTCGCACCATCTGCAGCCGAATTTGAAAAGACGCTTGAGCTGTGGCCGCGGTTG ATTGATTATGAGCTTTTGACCGACGACAAAGGCAAGCGCACTGTAGGATTTGGATGGTATGCAGGTGTCGCCGGT GTCCTTGAATCCTTGTCCGCCATGGCTCACGCCCACCTCGAACTCGGCATCGCCTCTCCCTTTCTCTACACGCCC CGACCTCATACGCTTCCGTGTCTTGAACGCCTTCGTGTTGCATTGCGCGAGGTTGGACAATGGATTTCTACGCAG GGTACTCCAAGGGCCCTTGGTCCTTTGGTTATCTGCGTCACTGGAACGGGTAACGTTGCTCAGGGGTGCCTCTCC ATCCTCGAGGACCTGCCACTGAAGAAGATTGATGTACGTGAATTAGAGAGTCTCGTACGCTCAGACGGCACGTCG GACTTGTTCACACTCGCTCAACTACTGACAATGAATGACCAGATATACTTGGTGCACGCGAAACCACAAGATTAT TTAGTTCGGAAAGACGGCAAGTCATATGATCGCCAGGATTATTATGCAAACCCTAGCGAGTGGCAAAGTCTATTT GGCGAACGCATTATGCCCTATGTGACTCTTTTCCTCAATGGCACCGGGTGGGCATCCGGTTTCCCTTCCATCTTG ACTACCCAGCAACTTTCAAATGCTATTGCGAAAGCGCAGTCTCTTGGTATTCCTAGTGCTGTCACCAGAGCTAGA TGCATCGGTGATATCAGCTGCGATATTGGGGGAGGCCTTGAATTCCTGGAACGTTCAACTACGATCTCTGAACCG ACTTACAAATTTGCTGTTTCTGATACGAGTGGCGATATCACCATGATGTCAGTTGATATTCTCCCCACTGCACTT CCGTTAGACGCATCGCGACATTTTTCGAAAGAATTTTTCCCTTATCTTCGTACACTCATAAATCAAGTTGGGAAG AGTAATAATAAGGGTGGTGGTGAAGAGTTGACGAGAGCACTTGAGAGAGCGACGATTGCGTCTAATGGAAAATTG AAGGAGAAGCATGAATGGTTGCAGCCTGCGGTGGATCAATGGCATCAAGAACAAAGAGGTGTGAAAGGAATACAA CATATGAATGATTCTGTTCAAGTTGGTGGGACTGGTGCGGATAGGATTAGAGGTGTGAAGAAGAAGAAGATGGTG ATGTTTGGAAGTGGGATGGTTGCTGGACCTGCGGTTGAGGAGATTGCGAAAAGGGGGGATGTTGAACTTGTTATT GCGACGAATTTACTGGGAGAGGCTCAGAAGCTTGCGATACGATATGGACAGGAACATAATAATATCAAGTATCGG ATTGTGGATGTTGCGAAGAAGGAGACTTATGAGCATTTGGTTAATGAGGCGGATGTTGTCATCAGTTTGTTACCT GCGGCATATCATGTTGATATTGCGGAGATGTGTATTTCGGGAAAGAAACATCTCGTTACTGCATCTTACATCTCC GAACCCATGCGTCATCTCCATGATCGAGCCTTATCAGCTGATGTGTTGCTGCTTAATGAAATTGGACTTGATCCG GGGATAGATCATTGTTCAGCGATTTCGTTGATCAATGATTTGAAAGCAAAGGGAAAACAAGTTGTTTCGTTTACG TCGTTTTGTGGAGGATTGCCTGCACCGGATTCGATATTCGATACGTCGTCGTCGTCGTCGATGATGATGAAGAAG AGGGCGGTACCGTTGAAGTATAAATTTAGTTGGAGTCCTGTGGGTGTTTTGAGAGCTGCGAATCAGGGGGTGAGG TATTTGCTAAATGACAAGGTTGTGAAACTTCCGGGGATGGAGTTACTTCGGTCTGGGTTTCCGAGGTTACCGATT TTGAGTGGGAAGGAGGGTGATGGTGATGGCGTAGAGTTGGAGGGGATGCCGAATAGAGATAGTTTGCCGTATAGG GAGACTTATGGATTACGAGGTGAGGAGGGTGAGAGTTTGAGGACGTTGGTGCGAGGTACACTTCGGTATCCGGGG TTTTGTTCTTTGATGCAGTCGTTTAAGGATATTGGGTTGCTTGAAGATGGGAGGAAAATTCAAATTGGGGAGTGG AATGAGTTTTTGAGGCAAGTGCTTGCTGTGAGACTTGGATCGTCATCGTCGTTGGGTTTGGATGGGAGTTTGGAA AGTGCTCTTAGGGATGTGCAAGGGGTCGGAGAGAAGCAGTATGAGGAGACGATGGGTGCGTTGGAGTGGTTGGGT TTGTTGTCGAATTCGAATGGAGGAGGAGGGAAGAAGATGATGGTTCCGATGAAGGAAGCTACGCCTTTAGAGTTG TTTGCTATGGTTTTGGGAAACAAGTTGAAGTATGGGCCGATGGAAAGGGATATGGTCGTACTCTCTCATGAAGTT ATCGTTCGCAACAACCAAAACCAACAACAACCTCAACAAGAAGAAGTTCATCGATCGACTCTAGTCGCATATGGA GATGAATCCGCATCTGCTATGGCGAAAACGGTTGGTCTTCCTGTGGCGTTTGCAGCGCTAGATGTGTTGGATGGG AAAGTGGGGATGAGAGGGGTGTGTGGACCGAATGAGAGGGAGATTTATGAGAGTGTTTTGGGGAGGTTGGAGGAG GTTGGGTTGGGGATGGTTGAGAGTGTGGATTTGGTTGGGAGGGAGGGGTTGAGGACTGTAGAGGAGAGTTTGAGG GGGTAA
Gene	>Agabi119p4\|761400 ATGAAGCCCTCCCGATCACTGTTGCAGAATGTTGTCCTCGCCATGCGCAGAGAGGATCCAGCGAGGATCTGGGAA CGTCGCGCTCCTCTCACCCCCGACGCCGTCCACCATCTCGTCGAGAAGGACGGCGTCGAGGTCCTTGTCGAGCCC TGCGAACGACGTGTCTTTACAGCTCATGAATACGAAAAGGTAAGAGCGATCCTTTGATAGTGTGGCATTGACATC TCATCCTCGACAGGCTGGCGCAAAGATCACTTCCTCCTTTGACCGAGCACACGTTGTGATAGGCATCAAAGAGAA TCCAATGGACGCACTCGCAGGCCAGCGGGCTCCTGTTGCCAATGGAAACATACCCCGCACACAAGTCATGTTCTC ACATACCGCCAAAGGCCAAACCTACAACACCGGTCTGCTATCTCAGTTTGTCGCCCCGACAGACGGCGTCCTCGC ACCATCTGCAGCCGAATTTGAAAAGACGCTTGAGCTGTGGCCGCGGTTGATTGATTATGAGCTTTTGACCGACGA CAAAGGCAAGCGCACTGTAGGATTTGGATGGTATGCAGGTGGTAAGTGGATCCTCCCACGCATACACTTAGGGGT TGCTAATGACGTCCTAGTCGCCGGTGTCCTTGAATCCTTGTCCGCCATGGCTCACGCCCACCTCGAACTCGGCAT CGCCTCTCCCTTTCTCGTGAGTATCCACCGCCAGCACAGAGACTATCTCACGCAAAGGCCGGAGACAATCTGGAC GACAACCCATAACCTGACTCTAATACTTTCCTTCCACTTAGTACACGCCCCGACCTCATACGCTTCCGTGTCTTG AACGCCTTCGTGTTGCATTGCGCGAGGTTGGACAATGGATTTCTACGCAGGGTACTCCAAGGGCCCTTGGTCCTT TGGTTATCTGCGTCACTGGGTGCGTCACTCGACATCCGCTCATCCCCATTTTAATGATATCCTATTTTTAGAACG GGTAACGTTGCTCAGGGGTGCCTCTCCATCCTCGAGGACCTGCCACTGAAGAAGATTGATGTACGTGAATTAGAG AGTCTCGTACGCTCAGACGGTGAGCAGCTTACTTTTTCACGCTCGTGCTTGCTGCTCACGAAGTGTAGATTATGA TAACTCCAAGGCACGTCGGACTTGTTCACACTCGCTCAACTACTGACAATGAATGACCAGATATACTTGGTGCAC GCGAAACCACAAGATTATTTAGTTCGGAAAGACGGCAAGTCATATGATCGCCAGGATTATTATGCAAACCCTAGC GAGTGGCAAAGTCTATTTGGCGAACGCGTACGTGTCGTTATTGTCCTAGCGAGTCCTGTCCCTCAACTCTTGCGA TTCAGATTATGCCCTATGTGACTCTTTTCCTCAATGGCACCGGGTGGGCATCCGGTTTCCCTTCCATCTTGACTA CCCAGCAACTTTCAAATGCTATTGCGAAAGCGCAGTCTCTTGGTATTCCTAGTGCTGTCACCAGAGCTAGATGCA TCGGTGATATCAGCTGCGATATTGGGGTATGTGAATGTTTTTGATTCATCGTTTCTTTCCCTCTGATACTCTGAT AGGGAGGCCTTGAATTCCTGGAACGTTCAACTACGATCTCTGAACCGACTTACAAATTTGCTGTTTCTGATACGA GTGGCGATATCACCATGATGTCAGTTGATATTCTCCCCACTGCACTTCCGTTAGACGCATCGCGACATTTTTCGA AAGAATTTTTCCCTTATCTTCGTACACTCATAAATCAAGTTGGGAAGAGTAATAATAAGGGTGGTGGTGAAGAGT TGACGAGAGCACTTGAGAGAGCGACGATTGCGTCTAATGGAAAATTGAAGGAGAAGCATGAATGGTTGCAGCCTG CGGTGGATCAATGGCATCAAGAACAAAGAGGTGTGAAAGGAATACAACATATGAATGATTCTGTTCAAGTTGGTG GGACTGGTGCGGATAGGATTAGAGGTGTGAAGAAGAAGAAGATGGTGATGTTTGGAAGTGGGATGGTTGCTGGAC CTGCGGTTGAGGAGATTGCGAAAAGGGGGGATGTTGAACTTGTTATTGGTGAGAAGGTTATGCGCATATAATAGA GATCATTATCTCATTTGTTGTTGTTGTGTAGCGACGAATTTACTGGGAGAGGCTCAGAAGCTTGCGATACGATAT GGACAGGAACATAATAATATCAAGTATCGGATTGTGGATGTTGCGAAGAAGGAGACTTATGAGCATTTGGTTAAT GAGGCGGATGTTGTCATCAGGTATGATTCCGTTTGATAAAGTAATGTTTTGAGGTATTATTAACGCATTGATGTA GTTTGTTACCTGCGGCATATCATGTTGATATTGCGGAGATGTGTATTTCGGGAAAGAAACATCTCGTTACTGCAT CTTACATCTCCGAACCCATGCGTCATCTCCATGATCGGTATGTTTATGTTTTTTTTTTTTTTTTCCTTTTTCTCC TCCTCCTCCTCCTCACCTACTCATCTTTGTCTATATAATTAGAGCCTTATCAGCTGATGTGTTGCTGCTTAATGA AATTGGACTTGATCCGGGGATAGATCATTGTTCAGCGATTTCGTTGATCAATGATTTGAAAGCAAAGGGAAAACA AGTTGTTTCGTTTACGTCGTTTTGTGGAGGATTGCCTGCACCGGATTCGATATTCGATACGTCGTCGTCGTCGTC GATGATGATGAAGAAGAGGGCGGTACCGTTGAAGTATAAATTTAGTTGGAGTCCTGTGGGTGTTTTGAGAGCTGC GAATCAGGGGGTGAGGTATTTGCTAAATGACAAGGTGAATCTTTTGTCGTGATTTTGTTTTTTTTTTGTTGATTG GTTGTAGGTTGTGAAACTTCCGGGGATGGAGTTACTTCGGTCTGGGTTTCCGAGGTTACCGATTTTGAGTGGGAA GGAGGGTGATGGTGATGGCGTAGAGTTGGAGGGGATGCCGAATAGAGATAGTTTGCCGTATAGGGAGACTTATGG ATTACGAGGTGAGGAGGGTGAGAGTTTGAGGACGTTGGTGCGAGGTACACTTCGGTGAGTTCAACACAAACGAAA ATAACAACTTTTTTTTTTGGTTAATTGGTTGATTGGCGGTTGTTAGGTATCCGGGGTTTTGTTCTTTGATGCAGT CGTTTAAGGATATTGGGTTGCTTGAAGATGGGAGGAAAATTCAAATTGGGGAGTGGAATGAGTTTTTGAGGCAAG TGCTTGCTGTGAGACTTGGATCGTCATCGTCGTTGGGTTTGGATGGGAGTTTGGAAAGTGCTCTTAGGGATGTGC AAGGGGTCGGAGAGAAGCAGTATGAGGAGACGATGGGTGCGTTGGAGTGGTTGGGTTTGTTGTCGAATTCGAATG GAGGAGGAGGGAAGAAGATGATGGTTCCGATGAAGGAAGCTACGCCTTTAGAGTTGTTTGCTATGGTTTTGGGAA ACAAGTTGAAGTATGGGCCGATGGAAAGGGATATGGTCGTACTCTCTCATGAAGTTATCGTTCGCAACAACCAAA ACCAACAACAACCTCAACAAGAAGAAGTTCATCGATCGACTCTAGTCGCATATGGAGATGAATCCGCATCTGCTA TGGCGAAAACGGTTGGTCTTCCTGTGGCGTTTGCAGCGCTAGATGTGTTGGATGGGAAAGTGGGGATGAGAGGGG TGTGTGGACCGAATGAGAGGGAGATTTATGAGAGTGTTTTGGGGAGGTTGGAGGAGGTTGGGTTGGGGATGGTTG AGAGTGTGGATTTGGTTGGGAGGGAGGGGTTGAGGACTGTAGAGGAGAGTTTGAGGGGGTAA

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